San Francisco
Panama City
Visit San Francisco
Stay near popular San Francisco attractions
Things to do
Panama City: All-Inclusive Catamaran Cruise to Taboga Island
P6,177
per adult
94% of travellers recommend
From Panama City: San Blas Island Hopping Day Tour
P9,047
per adult
98% of travellers recommend
Half day of Panama city and canal tour: shared and private
P4,168
per adult
96% of travellers recommend
Panama City Visit an Indian town Embera and waterfall with lunch
P2,876
per adult
96% of travellers recommend
Panama Canal: The Most Complete Wildlife Experience
P3,001
per adult
98% of travellers recommend
Top hotels in San Francisco
Megapolis Hotel Panamá
Avenida Balboa Panama City
The price is P10,047 per night from Oct 26 to Oct 27
P10,047
P11,052 total
Oct 26 - Oct 27
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Ramada Plaza by Wyndham Panama Punta Pacifica
Via Israel y Calle 71, San Francisco Panama City Panama
The price is P6,540 per night from Nov 1 to Nov 2
P6,540
P7,194 total
Nov 1 - Nov 2
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,367 reviews)
"Todo bien"
Reviewed on Oct 3, 2026
Decapolis Hotel Panama City
Avenida Balboa Con Multicentro Panama City Panama
The price is P5,935 per night from Oct 31 to Nov 1
P5,935
P6,529 total
Oct 31 - Nov 1
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,732 reviews)
"Excellent hotel with a convenient price with the breakfast included."
Reviewed on Oct 2, 2026
Courtyard by Marriott Panama Multiplaza Mall
Via Israel Multiplaza Pacific Mall Panama City Panama
The price is P7,101 per night from Oct 31 to Nov 1
P7,101
P7,811 total
Oct 31 - Nov 1
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
9/10 Wonderful! (1,007 reviews)
"Good place close to shipping"
Reviewed on Oct 4, 2026
Aloft by Marriott Panama
Via Israel & Calle 76 Panama City Panama
The price is P8,276 per night from Oct 10 to Oct 11
P8,276
P9,103 total
Oct 10 - Oct 11
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a nightclub. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (1,000 reviews)
"The bar and the cleanliness of the room were great. Breakfast selection options was also good."
Reviewed on Sep 28, 2026
Las Americas Golden Tower Panama
Av. Balboa con Calle 53 Panama City Panama
The price is P9,503 per night from Oct 11 to Oct 12
P9,503
P10,453 total
Oct 11 - Oct 12
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in San Francisco
Find the best San Francisco areas and neighborhoods for the activities you enjoy most.
Casco Viejo
Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
Photo by Journey Of A Nomadic Family
Open Photo by Journey Of A Nomadic Family
Bella Vista
Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station.
El Cangrejo
The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.
San Felipe
If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.
Calidonia
You might enjoy the shopping while in Calidonia. Via Espana is a notable sight, and you can get around town at Lotería Station or Santo Tomás Station to see more of the city.
