San Francisco
Panama City
Visit San Francisco
Stay near popular San Francisco attractions
Things to do
Half day of Panama city and canal tour: shared and private
P4,102
per adult
98% of travellers recommend
Panama Canal: The Most Complete Wildlife Experience
P2,916
per adult
96% of travellers recommend
All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City
P6,092
per adult
94% of travellers recommend
Panama City: Poin Glass Observation Deck Ticket with VR Tour
P1,975
per adult
100% of travellers recommend
Top hotels in San Francisco
Megapolis Hotel Panamá
Avenida Balboa Panama City
The price is P12,115 per night from Sep 7 to Sep 8
P12,115
P13,327 total
Sep 7 - Sep 8
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.4/10 Very Good! (1,680 reviews)
"Room was clean. Hotel smells amazing.breakfast great. All amenities are close by. Will definitely stay here again. Ubers to wherever you need to go was cheap as hotel is centrally close to attractions and old Panama."
Reviewed on Aug 19, 2026
Aloft by Marriott Panama
Via Israel & Calle 76 Panama City Panama
The price is P8,175 per night from Aug 28 to Aug 29
P8,175
P8,992 total
Aug 28 - Aug 29
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a nightclub. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (1,006 reviews)
"Nice hotel, rooms are comfortable and clean. Breakfast is ok with some alternatives"
Reviewed on Aug 19, 2026
Courtyard by Marriott Panama Multiplaza Mall
Via Israel Multiplaza Pacific Mall Panama City Panama
The price is P7,300 per night from Sep 6 to Sep 7
P7,300
P8,030 total
Sep 6 - Sep 7
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
9/10 Wonderful! (1,015 reviews)
"Love it"
Reviewed on Aug 19, 2026
JW Marriott Panama
Calle Punta Colon, Punta Pacifica Panama City Panama
The price is P16,757 per night from Sep 19 to Sep 20
P16,757
P18,433 total
Sep 19 - Sep 20
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (1,004 reviews)
"The employees were friendly and effective. Also, the gym was well equipped. Given my satisfaction, I plan to return. One thing that will make the hotel more family friendly is to have an indoor play area and ball pit for the small children of guests."
Reviewed on Aug 16, 2026
Decapolis Hotel Panama City
Avenida Balboa Con Multicentro Panama City Panama
The price is P6,866 per night from Sep 17 to Sep 18
P6,866
P7,553 total
Sep 17 - Sep 18
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,708 reviews)
"Good environment , stuff etc and the location very close to the malls , and other restaurants"
Reviewed on Aug 17, 2026
Las Americas Golden Tower Panama
Av. Balboa con Calle 53 Panama City Panama
The price is P10,005 per night from Aug 30 to Aug 31
P10,005
P11,005 total
Aug 30 - Aug 31
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in ...
9/10 Wonderful! (1,088 reviews)
"It’s a beautiful resort but it’s old and well kept"
Reviewed on Aug 18, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in San Francisco
Find the best San Francisco areas and neighborhoods for the activities you enjoy most.
Casco Viejo
Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
Photo by My World
Open Photo by My World
Bella Vista
Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station.
El Cangrejo
The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.
Punta Paitilla
Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.
San Felipe
If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.
