San Francisco

Panama City

Photo by Hideki Yamagata
Photo by ‎James Barrow
Photo by Adrian Damian
Photo by Nóra Széll
Photo by Panama Roadrunner

Popular places to visit

Things to do


Top hotels in San Francisco

Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street, Panama City, Panama
The price is P7,800 per night from Aug 10 to Aug 11
P7,800
P8,580 total
Aug 10 - Aug 11
includes taxes & fees
Stay at this 4-star spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.4/10 Very Good! (914 reviews)
"Me and my husband loved staying there! Superb hotel beyond international standards! The staff was so friendly and attentive. The hotel is gorgeous! The pool is amazing and so is the spa. The breakfast buffet is excellent. I only have the best words to describe this place! I hope to stay there when ..."

Reviewed on Jul 26, 2025

Sheraton Grand Panama
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
The price is P12,310 per night from Aug 16 to Aug 17
P12,310
P13,541 total
Aug 16 - Aug 17
includes taxes & fees
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
8.8/10 Excellent! (1,000 reviews)
"Always an exceptional stay."

Reviewed on Jul 30, 2025

JW Marriott Panama
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa, Panama City
The price is P7,388 per night from Aug 24 to Aug 25
P7,388
P8,127 total
Aug 24 - Aug 25
includes taxes & fees
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.2/10 Very Good! (989 reviews)
"Lovely hotel"

Reviewed on Aug 1, 2025

Megapolis Hotel Panamá
Ramada Plaza By Wyndham Panama Punta Pacífica

Ramada Plaza By Wyndham Panama Punta Pacífica

4 out of 5
Via Israel y Calle 71, San Francisco, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is P6,392 per night from Aug 11 to Aug 12
P6,392
P7,031 total
Aug 11 - Aug 12
includes taxes & fees
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,004 reviews)
"Very clean and spacious room. We were surprised upon check in. Great value!"

Reviewed on Aug 3, 2025

Ramada Plaza By Wyndham Panama Punta Pacífica
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro, Panama City, Panama
The price is P5,527 per night from Aug 8 to Aug 9
P5,527
P6,080 total
Aug 8 - Aug 9
includes taxes & fees
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,263 reviews)
"Safe and walkable"

Reviewed on Aug 1, 2025

Decapolis Hotel Panama City
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53, Paitilla, Panama City, Panama
The price is P10,210 per night from Aug 18 to Aug 19
P10,210
P11,230 total
Aug 18 - Aug 19
includes taxes & fees
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,002 reviews)
"The breakfast was very good with an ample array of options everyday. The staff was very friendly, always looking out for their guest and providing great tips. The view was very neat and perfect for Instagram! The hotel was impecable and the gym was bigger than I expected. The room is modern, very ..."

Reviewed on Aug 2, 2025

Las Americas Golden Tower Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around San Francisco

Default Image

Obarrio

Unique features of Obarrio include the casinos and coffeehouses. Make a stop by Calle 50 or Soho City Center while you're exploring the area.

Obarrio
Default Image

Punta Pacifica

Notable for its seaside views, restaurants, and casinos, Punta Pacifica is a sought-after destination for many travelers visiting Panama City. If you want to see some sights in the area, check out Pacific Center or Avenida Balboa.

Punta Pacifica
Default Image

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

Punta Paitilla
Default Image

Campo Alegre

If you're spending some time in Campo Alegre, Uruguay Street and Calle 50 are top sights worth seeing.

Campo Alegre
Default Image

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

El Cangrejo
Default Image

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

Bella Vista

San Francisco