San Francisco
Panama City
Visit San Francisco
Stay near popular San Francisco attractions
Things to do
Panama City Visit an Indian town Embera and waterfall with lunch
P2,681
per adult
96% of travellers recommend
All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City
P6,019
per adult
94% of travellers recommend
Panama City: POIN Swing Experience
P1,951
per adult
100% of travellers recommend
Half day of Panama city and canal tour: shared and private
P4,053
per adult
98% of travellers recommend
Panama City: Poin Glass Observation Deck Ticket with VR Tour
P1,951
per adult
100% of travellers recommend
Top hotels in San Francisco
Megapolis Hotel Panamá
Avenida Balboa Panama City
The price is P8,075 per night from Aug 4 to Aug 5
P8,075
P8,883 total
Aug 4 - Aug 5
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.4/10 Very Good! (1,579 reviews)
"The rooftop wasn’t open unfortunately, otherwise this was a stay with an an amazing view of the screw building. The room was huge and it felt safe."
Reviewed on Jul 4, 2026
JW Marriott Panama
Calle Punta Colon, Punta Pacifica Panama City Panama
The price is P17,642 per night from Aug 1 to Aug 2
P17,642
P19,406 total
Aug 1 - Aug 2
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (1,000 reviews)
"The Marriott was a beautiful hotel. Helpful staff. Recommended"
Reviewed on Jun 29, 2026
Las Americas Golden Tower Panama
Av. Balboa con Calle 53 Panama City Panama
The price is P7,924 per night from Aug 2 to Aug 3
P7,924
P8,717 total
Aug 2 - Aug 3
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in ...
9/10 Wonderful! (1,049 reviews)
"Great location! Breakfast was good Overall nice stay"
Reviewed on Jul 4, 2026
Aloft by Marriott Panama
Via Israel & Calle 76 Panama City Panama
The price is P7,519 per night from Jul 25 to Jul 26
P7,519
P8,271 total
Jul 25 - Jul 26
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a nightclub. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (1,004 reviews)
"The property was beautiful and comforting. The staff was helping and pleasant. I love it. I definitely will be back there."
Reviewed on Jul 4, 2026
Courtyard by Marriott Panama Multiplaza Mall
Via Israel Multiplaza Pacific Mall Panama City Panama
The price is P6,736 per night from Jul 25 to Jul 26
P6,736
P7,409 total
Jul 25 - Jul 26
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
9/10 Wonderful! (1,003 reviews)
"Great service Wonderfull location Amenities like swimming pool, little downside."
Reviewed on Jul 4, 2026
Sheraton Grand Panama
Via Israel And 77th Street Panama City Panama
The price is P8,569 per night from Jul 24 to Jul 25
P8,569
P9,426 total
Jul 24 - Jul 25
includes taxes & fees
Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,003 reviews)
"Bathroom needs some updates, especially the faucets."
Reviewed on Jun 19, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in San Francisco
Find the best San Francisco areas and neighborhoods for the activities you enjoy most.
Casco Viejo
Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
Photo by My World
Open Photo by My World
Bella Vista
Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.
El Cangrejo
The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.
Calidonia
You might enjoy the shopping while in Calidonia. Via Espana is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city.
Punta Paitilla
Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Pacific Center while you're in town.
