Serra Mesa

San Diego

A residential area with houses, roads, and a hilly landscape.

Stay near popular Serra Mesa attractions

Civita Dog Park

After visiting Civita Dog Park, make a plan to see the other sights and activities in San Diego.
See properties

Things to do

San Diego Old Town Trolley Hop-On Hop-Off Tour

San Diego Old Town Trolley Hop-On Hop-Off Tour

P3,557
per adult
94% of travellers recommend
San Diego Old Town Trolley Hop-On Hop-Off Tour
Oceanside Whale and Dolphin Watching Adventures

Oceanside Whale and Dolphin Watching Adventures

P3,564
per adult
90% of travellers recommend
Oceanside Whale and Dolphin Watching Adventures
San Diego: Luggage Storage in Marina

San Diego: Luggage Storage in Marina

P696
per adult
San Diego: Luggage Storage in Marina
San Diego Premier Dinner Cruise

City Cruises San Diego: Premier Dinner Cruise

P7,982
per adult
90% of travellers recommend
City Cruises San Diego: Premier Dinner Cruise
San Diego Best of the Bay Harbor Tour

City Cruises San Diego: Best of the Bay Harbor Tour

P1,928
per adult
100% of travellers recommend
City Cruises San Diego: Best of the Bay Harbor Tour
San Diego: 3 Hour Whale Watching Cruise

San Diego: 3 Hour Whale Watch Cruise with Legacy Whale Watch

P2,121
per adult
92% of travellers recommend
San Diego: 3 Hour Whale Watch Cruise with Legacy Whale Watch
See all activities in San Diego

Top hotels in Serra Mesa

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
The price is P11,742 per night from Oct 31 to Nov 1
P11,742
P16,809 total
Oct 31 - Nov 1
includes taxes & fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
Paradise Point Resort & Spa
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
The price is P5,573 per night from Oct 1 to Oct 2
P5,573
P6,406 total
Oct 1 - Oct 2
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the restaurant in our ...
Best Western Seven Seas
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
The price is P9,522 per night from Oct 25 to Oct 26
P9,522
P13,218 total
Oct 25 - Oct 26
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
Wyndham San Diego Bayside
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
The price is P6,458 per night from Oct 5 to Oct 6
P6,458
P7,424 total
Oct 5 - Oct 6
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...
8.4/10 Very Good! (2,978 reviews)
"I had a good stay at the Handlery Hotel. The room was clean, comfortable, and well maintained. There wasn’t much of a view, but overall, it was a good place to stay for the night and felt better than some of the cheaper hotels I’ve stayed at. Unfortunately, I wasn’t able to use the pool during my ..."

Reviewed on Sep 30, 2026

Handlery Hotel
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
The price is P14,331 per night from Oct 25 to Oct 26
P14,331
P20,026 total
Oct 25 - Oct 26
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy 6 restaurants, 3 bars/lounges, and breakfast (surcharge). Our guests praise the pool and the ...
Manchester Grand Hyatt San Diego
California Suites Hotel

California Suites Hotel

2 out of 5
5415 Clairemont Mesa Blvd San Diego CA
The price is P5,573 per night from Oct 11 to Oct 12
P5,573
P6,395 total
Oct 11 - Oct 12
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...
California Suites Hotel
See all 9,158 properties in Serra Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Serra Mesa

Find the best Serra Mesa areas and neighborhoods for the activities you enjoy most.
A large stadium with the sign "Cobo Park" and palm trees around it.

Downtown San Diego

Petco Park and Port of San Diego are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.

A pier at sunset with people sitting and standing, waves crashing below.

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.

A coastal cityscape with a long sandy beach, a pier, and dense urban buildings.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

A theater marquee with ornate designs and the name "Gaslamp Quarter".

Gaslamp Quarter

Fantastic nightlife and popular shops are a few of the things travelers enjoy most about Gaslamp Quarter. A visit to Gaslamp Museum at the Davis-Horton House or Nova SD is also recommended, and you can jump aboard the metro at Gaslamp Quarter Station to get around town.

An aerial view of a coastal city with a marina, a large body of water, and a peninsula with buildings.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.

Serra Mesa