Serra Mesa
San Diego
Visit Serra Mesa
Popular places to visit

San Diego Zoo
One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.

San Diego Convention Center
During your trip, find out what's happening at San Diego Convention Center, a top convention center in San Diego. Experience the area's fascinating museums and acclaimed art scene.

Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.

Petco Park
Purchase a hot dog and watch the San Diego Padres, California’s southernmost Major League Baseball team, play on their home field.

Mission Beach
A seaside village and a popular spot for holiday-makers for over a century, which today still retains its antique charm.

SeaWorld
A fun family favourite, where you can get up close to the local marine life, enjoy fun rides and be wowed by the performances.
Things to do

San Diego City Lights Night Tour

San Diego Sunset Cruise from Mission Bay

San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway

San Diego Whale Watching Tour

Crossing Borders: Tijuana Day Trip from San Diego

Coronado: San Diego Bay Jetski Rental
Top hotels in Serra Mesa

Wyndham San Diego Bayside
Reviewed on Sep 15, 2025

Hotel del Coronado, Curio Collection by Hilton
Reviewed on Sep 16, 2025

The DEXTRO Little Italy, BW Premier Collection
Reviewed on Sep 15, 2025

Palihotel San Diego Gaslamp Quarter
Reviewed on Sep 15, 2025

Bay Club Hotel & Marina
Reviewed on Sep 16, 2025

Hard Rock Hotel San Diego
Reviewed on Sep 16, 2025
Other neighbourhoods around Serra Mesa

Mission Valley
Known for its stunning beaches and popular shops, there's plenty to explore in Mission Valley. Check out top attractions like Fashion Valley Mall and Snapdragon Stadium, and jump on the metro at Hazard Center Station or Mission Valley Center Station to see more of the city.

North Park
North Park is well-liked for its restaurants. You can also take some time to explore sights in the surrounding area like San Diego Zoo and San Diego Natural History Museum.

Hillcrest
Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.

Del Cerro
Del Cerro might not have many top sights, but Cal Coast Credit Union Open Air Theater and Viejas Arena are two attractions nearby that you can check out.

Old Town San Diego
The ample dining options and beautiful seaside views are top of the list for many visitors to Old Town San Diego. A stop by Old Town San Diego State Park or Whaley House Museum might round out your trip.

Little Italy
Little Italy is popular for its captivating waterfront views. Explore top sights like Maritime Museum of San Diego and San Diego Bay, and you can get around town on the metro at County Center - Little Italy Station.