Serra Mesa
San Diego
Visit Serra Mesa
Popular places to visit
San Diego Zoo
One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.
San Diego Convention Center
During your trip, find out what's happening at San Diego Convention Center, a top convention center in San Diego. Experience the area's acclaimed art scene and entertainment choices.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
Petco Park
Purchase a hot dog and watch the San Diego Padres, California’s southernmost Major League Baseball team, play on their home field.
Mission Beach
A seaside village and a popular spot for holiday-makers for over a century, which today still retains its antique charm.
SeaWorld
A fun family favourite, where you can get up close to the local marine life, enjoy fun rides and be wowed by the performances.
Things to do
San Diego Whale Watching & Dolphin Cruise
San Diego Old Town Trolley Hop-On Hop-Off Tour
San Diego Sunset Cruise from Mission Bay
San Diego Whale Watching Cruise
Haunted San Diego: The Only Ghost Tour with Exclusive Entry
Top hotels in Serra Mesa
Hilton San Diego Mission Valley
Amazing!
Reviewed on Nov 3, 2025
Hampton Inn & Suites by Hilton San Diego SeaWorld
Very clean room. Front desk was excellent.
Reviewed on Nov 2, 2025
Pendry San Diego
Great room and great staff! They really made our stay with their hospitality and efficiency.
Reviewed on Nov 2, 2025
Hard Rock Hotel San Diego
The room and service was excellent.
Reviewed on Nov 3, 2025
Courtyard by Marriott San Diego Downtown Little Italy
Staff is amazing 3 time staying here for a reason really. Great place
Reviewed on Oct 28, 2025
InterContinental San Diego by IHG
The staff was very nice. Our room was amazing ! We got a corner room and it was so spacious !
Reviewed on Nov 2, 2025
Other neighbourhoods around Serra Mesa
Mission Valley
Known for its stunning beaches and popular shops, there's plenty to explore in Mission Valley. Check out top attractions like Fashion Valley Mall and Snapdragon Stadium, and jump on the metro at Hazard Center Station or Mission Valley Center Station to see more of the city.
North Park
North Park is well-liked for its restaurants. You can also take some time to explore sights in the surrounding area like San Diego Zoo and San Diego Natural History Museum.
Hillcrest
Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.
Del Cerro
Del Cerro might not have many top sights, but Cal Coast Credit Union Open Air Theater and Viejas Arena are two attractions nearby that you can check out.
Old Town San Diego
The ample dining options and beautiful seaside views are top of the list for many visitors to Old Town San Diego. A stop by Old Town San Diego State Park or Whaley House Museum might round out your trip.
Mid-City
If you're spending time in Mid-City, check out sights like Cal Coast Credit Union Open Air Theater or Viejas Arena and hop on the metro to see more the city at SDSU Transit Center Station or Alvarado Station.
