Hotels near Roswell Park Cancer Institute

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Our top choices for Roswell Park Cancer Institute hotels

Buffalo Harmony House

Buffalo Harmony House
4.5 star property
Allentown, 1.2 km from Roswell Park Cancer Institute
10.0 out of 10, Exceptional, (47)
"Amazing breakfasts!"
United States
David
Buffalo Harmony House

InnBuffalo off Elmwood

InnBuffalo off Elmwood
2.5 star property
Elmwood Village, 2.5 km from Roswell Park Cancer Institute
10.0 out of 10, Exceptional, (190)
"Our favorite inn!! Beautifully and lovingly restored — wonderful staff, rooms, fresh breakfasts…a gem, to be sure."
United States
katherine
The price is P7,314
P8,394 total
includes taxes & fees
Jan 8 - Jan 9, 2026
InnBuffalo off Elmwood

The Mansion On Delaware Ave

The Mansion On Delaware Ave
4.0 star property
Allentown, 0.8 km from Roswell Park Cancer Institute
9.4 out of 10, Exceptional, (1000)
"Fantastic place!"
Canada
Geneviève
The Mansion On Delaware Ave

Wyndham Garden Buffalo Downtown

Wyndham Garden Buffalo Downtown
3.0 star property
Downtown Buffalo, 0.2 km from Roswell Park Cancer Institute
9.0 out of 10, Wonderful, (1717)
"Great hotel!"
United States
Donovan
The price is P7,263
P8,480 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Wyndham Garden Buffalo Downtown

Curtiss Hotel, an Ascend Collection Hotel

Curtiss Hotel, an Ascend Collection Hotel
5.0 star property
Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute
9.4 out of 10, Exceptional, (1000)
"Beautiful hotel, beautiful room, outside hot tub and excellent restaurant "
United States
valerie
The price is P12,219
P14,266 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Curtiss Hotel, an Ascend Collection Hotel

The Edward Hotel

The Edward Hotel
3.0 star property
Elmwood Village, 2.3 km from Roswell Park Cancer Institute
9.6 out of 10, Exceptional, (219)
"Great location in Elmwood Village area. Clean room with gas fireplace. Self check- in was easy with staff provided instructions. Many food options within walking distance. "
United States
Jon
The Edward Hotel

Buffalo Guesthouse

Buffalo Guesthouse
3.0 star property
Allentown, 0.5 km from Roswell Park Cancer Institute
9.0 out of 10, Wonderful, (119)
"Fantastic stay at the Buffalo Guesthouse. It has a real home feeling. Lovely staff( real friendly atmosphere where you actually engage with other people staying there. Clean, well located and secure. "
Australia
Benjamin
The price is P5,772
P6,624 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Buffalo Guesthouse

The Westin Buffalo

The Westin Buffalo
4.0 star property
Buffalo Theater District, 1.2 km from Roswell Park Cancer Institute
9.2 out of 10, Wonderful, (401)
"Our go-to in Buffalo ,,"
Canada
Sarah
The price is P17,972
P20,982 total
includes taxes & fees
Jan 5 - Jan 6, 2026
The Westin Buffalo

Residence Inn by Marriott Buffalo Downtown

Residence Inn by Marriott Buffalo Downtown
3.0 star property
Allentown, 0.7 km from Roswell Park Cancer Institute
9.0 out of 10, Wonderful, (335)
"This property was above and beyond awesome! We definitely will stay there again if we ever travel around the area again!!"
United States
Chauntel
The price is P12,887
P15,046 total
includes taxes & fees
Dec 29 - Dec 30
Residence Inn by Marriott Buffalo Downtown

Buffalo Marriott at LECOM HARBORCENTER

Buffalo Marriott at LECOM HARBORCENTER
3.5 star property
Downtown Buffalo, 2.6 km from Roswell Park Cancer Institute
9.4 out of 10, Exceptional, (891)
"Our stay was amazing! The staff at the front desk was very helpful. "
United States
Bobbi Jo
The price is P13,187
P15,396 total
includes taxes & fees
Dec 29 - Dec 30
Buffalo Marriott at LECOM HARBORCENTER

Hampton Inn & Suites Buffalo Downtown

Hampton Inn & Suites Buffalo Downtown
2.5 star property
Buffalo Theater District, 1.2 km from Roswell Park Cancer Institute
8.8 out of 10, Excellent, (1006)
"Hotel was very clean and the staff was friendly. My room was larger than expected. Breakfast was well stocked and had good variety. Great location also!"
United States
Holly
The price is P7,802
P9,109 total
includes taxes & fees
Jan 20 - Jan 21, 2026
Hampton Inn & Suites Buffalo Downtown

Best Western on the Avenue

Best Western on the Avenue
2.5 star property
Allentown, 0.7 km from Roswell Park Cancer Institute
8.6 out of 10, Excellent, (1002)
"The rooms were great. The staff was friendly and professional. Breakfast was awesome. Allentown location was ideal. I would stay here for my next visit."
United States
DAVID
The price is P7,877
P9,196 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Best Western on the Avenue

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG
2.5 star property
Buffalo Theater District, 1.1 km from Roswell Park Cancer Institute
8.6 out of 10, Excellent, (1006)
"Staff was pleasant, our suite was clean and well kept. Great breakfast! "
United States
Tricia
The price is P6,930
P8,092 total
includes taxes & fees
Dec 30 - Dec 31
Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Courtyard Buffalo Downtown / Canalside

Courtyard Buffalo Downtown / Canalside
3.0 star property
Downtown Buffalo, 2.4 km from Roswell Park Cancer Institute
9.0 out of 10, Wonderful, (959)
"Nice rooms, great location "
United States
Ellen
The price is P9,954
P11,621 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Courtyard Buffalo Downtown / Canalside

Hilton Garden Inn Buffalo Downtown

Hilton Garden Inn Buffalo Downtown
3.0 star property
Buffalo Theater District, 1.5 km from Roswell Park Cancer Institute
8.6 out of 10, Excellent, (1004)
"Everything was great! Thank you for the stay"
Canada
Sydney
The price is P5,608
P6,547 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Hilton Garden Inn Buffalo Downtown

Hotel at the Lafayette Trademark Collection by Wyndham

Hotel at the Lafayette Trademark Collection by Wyndham
3.5 star property
Buffalo Theater District, 1.6 km from Roswell Park Cancer Institute
8.6 out of 10, Excellent, (1001)
"I love the history in the hotel "
United States
Dylan
The price is P6,789
P7,927 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Hotel at the Lafayette Trademark Collection by Wyndham

Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center
3.5 star property
Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute
8.2 out of 10, Very Good, (1684)
"Checkin staff very helpful, efficient and pleasant. "
Canada
Carole
The price is P7,144
P8,340 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Hyatt Regency Buffalo / Hotel and Conference Center

Aloft Buffalo Downtown

Aloft Buffalo Downtown
3.0 star property
Buffalo Theater District, 0.8 km from Roswell Park Cancer Institute
8.2 out of 10, Very Good, (347)
"Clean room. Easy access to parking garage. "
United States
Clay
The price is P11,923
P13,920 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Aloft Buffalo Downtown

Embassy Suites Buffalo

Embassy Suites Buffalo
3.5 star property
Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute
8.2 out of 10, Very Good, (1001)
"Excellent breakfast and dinner onsite. Efficient valet parking"
United States
Delos
The price is P9,584
P11,189 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Embassy Suites Buffalo

Summer Street Guest House

Summer Street Guest House
3.0 star property
Bryant, 1.3 km from Roswell Park Cancer Institute
10.0 out of 10, Exceptional, (2)
"Beautiful old mansion lovingly restored with so much charm! This was a fantastic location for our needs. We were able to walk past estates and cute cottages with beautiful gardens to shops and restaurants for breakfast and lunch. Close to the Buffalo History Museum and other local attractions and about 20 minutes from Niagara Falls. Our host was able to let us have an early check in time and he gave us a tour of the house with some interesting background info. He lives quietly on the third...
United States
Anonymous traveler
The price is P21,091
P30,941 total
includes taxes & fees
Dec 29 - Dec 30
Summer Street Guest House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Roswell Park Cancer Institute Hotel Reviews

Hotels near other Roswell Park Cancer Institute attractions

Frequently asked questions

What's the area like around Roswell Park Cancer Institute?
Roswell Park Cancer Institute is located in a historic area of Buffalo known for its popular theater scene. If you're looking for a convenient place to stay, check out the 67 hotels and other accommodations you'll find within a mile.
What's the best hotel to stay close to Roswell Park Cancer Institute?
Adjacent to Roswell Park Cancer Institute, Wyndham Garden Buffalo Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a 24-hour fitness center. Other good choices close by include Hyatt Regency Buffalo / Hotel and Conference Center and Buffalo Guesthouse.
How many hotels will I find near Roswell Park Cancer Institute?
Expedia has 67 hotels and other accommodations within a mile from Roswell Park Cancer Institute.
If I need to cancel the hotel reservation for my stay near Roswell Park Cancer Institute, will I receive a refund?
Yes! Most hotel reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, it may still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then you can use the "fully refundable" filter to review the top deals on offer near Roswell Park Cancer Institute.
What can I see and do near Roswell Park Cancer Institute?
You might want to spend some time browsing the exhibits at Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site, Buffalo Museum of Science, or Buffalo and Erie County Naval and Military Park. Statler Tower, Ellicott Square Building, and Peace Bridge are monuments to see when you're exploring the area around Roswell Park Cancer Institute. You can catch a show at Shea's Performing Arts Center, Kleinhans Music Hall, and Road Less Traveled Theater.
How can I get to Roswell Park Cancer Institute?
With so many transportation options, seeing all of the area near Roswell Park Cancer Institute is easy. Take advantage of metro transit at Fountain Plaza Station, Lafayette Square Station, and Church Station. If you're taking a train into town, Buffalo-Exchange Street Station is the closest stop to Downtown Buffalo.