Top 10 Hotels Near Roswell Park Cancer Institute in Buffalo for 2026

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Our top choices for Roswell Park Cancer Institute hotels

A grand staircase with ornate woodwork and a chandelier, leading to a room with a large wooden door and a stained glass window.

A grand room with a chandelier, a fireplace, and ornate furniture.

A spacious room with a wooden floor, a fireplace, a dining area with a table and chairs, and a large rug.

A room with a red patterned sofa, wooden bookshelves, a chandelier, and a traditional wooden coffee table.

1. InnBuffalo off Elmwood

Elmwood Village, 2.5 km from Roswell Park Cancer Institute

Terese

P8,647

P9,923 total

includes taxes & fees

Nov 9 - Nov 10

A spacious room with a wooden floor, a fireplace, a dining table, and several chairs.

A room with a textured ceiling, a chandelier, and walls painted in a two-tone color scheme.

A historic building with a prominent tower and a traditional brick facade.

A grand hallway with a wooden staircase, a chandelier, and a patterned floor.

2. Buffalo Harmony House

Allentown, 1.2 km from Roswell Park Cancer Institute

John

P20,460

P23,792 total

includes taxes & fees

Oct 13 - Oct 14

A spacious dining area with a long table, multiple chairs, a chandelier, and a fireplace.

A grand staircase with a wooden handrail and a leopard print carpet, leading to a room with a large window and a door with frosted glass panels.

A living room with a fireplace, two leather armchairs, a coffee table, and a chandelier.

A spacious room with a large wooden table, several chairs, a sofa, and two chandeliers.

3. The Edward Hotel

Elmwood Village, 2.3 km from Roswell Park Cancer Institute

Grace

P8,104

P11,159 total

includes taxes & fees

Oct 13 - Oct 14

A modern hotel room with a large window, a sofa, a coffee table, and a TV.

A hotel lobby with a seating area, dining tables, and large windows offering views of the cityscape.

A modern kitchen with a central island, bar stools, and built-in appliances.

A spacious bedroom with a large bed, a comfortable armchair, and a view of a body of water through floor-to-ceiling windows.

4. Buffalo Marriott at LECOM HARBORCENTER

Downtown Buffalo, 2.6 km from Roswell Park Cancer Institute

Michael

P14,644

P17,096 total

includes taxes & fees

Oct 18 - Oct 19

A grand entrance with a staircase leading to a door, surrounded by lush greenery and a well-maintained garden.

A living room with a red wall, white furniture, a fireplace, and a large abstract painting.

A pool table in a room with dark walls, large windows, and green upholstered chairs.

A bar area with wooden furniture, a large wooden cabinet, and a clock on the wall.

5. The Mansion On Delaware Ave

Allentown, 0.8 km from Roswell Park Cancer Institute

Marilyn

P12,382

P14,208 total

includes taxes & fees

Oct 18 - Oct 19

A two-story building with a white exterior, a red door, and large windows.

A hot tub with a wooden fence and a brick building in the background.

A living room with a fireplace, leather sofa, and a television mounted on the wall.

A living room with a fireplace, a chandelier, leather sofas, and a glass coffee table.

6. Buffalo Guesthouse

Allentown, 0.5 km from Roswell Park Cancer Institute

Jan

P10,931

P12,543 total

includes taxes & fees

Oct 13 - Oct 14

A breakfast buffet with various food items and beverages, a large window with a view of buildings, and a patterned floor.

A heated outdoor swimming pool with lounge chairs and a bar area, surrounded by brick walls and a balcony with decorative lighting.

A circular fire pit with a metal railing, surrounded by a stone base, set on a tiled patio with a city skyline in the background.

7. Curtiss Hotel, an Ascend Collection Hotel

Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute

John

P16,500

P19,264 total

includes taxes & fees

Nov 11 - Nov 12

A spacious lobby with a large sofa, a coffee table, and potted plants. There is a decorative wall with a painting and a large window providing natural light.

A hotel dining area with multiple tables and chairs, a reception desk, and framed pictures on the walls.

A multi-story hotel with a modern facade, large windows, and a covered entrance area.

A modern lobby with a sofa set, coffee table, potted plants, and a large window providing natural light.

8. Wyndham Garden Buffalo Downtown

Downtown Buffalo, 0.2 km from Roswell Park Cancer Institute

Julian

P9,896

P11,553 total

includes taxes & fees

Oct 14 - Oct 15

A spacious lobby with modern furniture, large windows, and a high ceiling with exposed beams.

An outdoor patio area with seating, a fire feature, and a glass-enclosed space with greenery.

A gym with treadmills and a rowing machine, large windows, and a city view.

The Westin hotel entrance with a glass facade and a sign indicating it's now open.

9. The Westin Buffalo

Buffalo Theater District, 1.2 km from Roswell Park Cancer Institute

Sarah

P14,889

P17,382 total

includes taxes & fees

Oct 18 - Oct 19

A modern outdoor patio with stone walls, a fire feature, and outdoor furniture.

A modern lobby with a wooden reception desk, comfortable seating, and a decorative wall with shelves.

A modern lobby with a seating area, a fireplace, and a large window offering a view of the city.

A multi-story hotel with a modern design, featuring a prominent entrance with a covered walkway and a courtyard.

10. Courtyard Buffalo Downtown / Canalside

Downtown Buffalo, 2.4 km from Roswell Park Cancer Institute

Diana

P12,762

P14,900 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with a bed, desk, chair, TV, and a bathroom with a sink and mirror.

A modern gym with cardio machines, a mirrored wall, and a blue accent wall.

A modern hotel lobby with a round coffee table, two grey armchairs, a TV, and a reception desk.

A hotel lobby with a curved reception desk, a chandelier, a seating area with leather chairs, and a tiled floor.

11. Best Western on the Avenue

Allentown, 0.7 km from Roswell Park Cancer Institute

John

P9,556

P11,156 total

includes taxes & fees

Oct 18 - Oct 19

A hotel with a prominent red sign, large windows, and a parking lot with multiple cars.

A breakfast buffet with various pastries, fruits, and bread.

A modern living room with a fireplace, comfortable seating, and a herringbone-patterned wall.

A hotel room with a sofa, a desk, a chair, a television, and a large mirror.

12. Hampton Inn & Suites Buffalo Downtown

Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute

Gerald D

P10,626

P12,406 total

includes taxes & fees

Oct 18 - Oct 19

An indoor swimming pool with tiled walls, a lifeguard chair, and a pool ladder.

A hotel room with a bed, a desk, a chair, and a view of a cityscape through large windows.

The exterior of the Hilton Garden Inn, featuring a prominent entrance with a large sign, a flag, and a well-maintained sidewalk.

A modern lobby with a leather sofa, a fireplace, and a television mounted on the wall.

13. Hilton Garden Inn Buffalo Downtown

Buffalo Theater District, 1.5 km from Roswell Park Cancer Institute

Mercedes

P9,985

P11,658 total

includes taxes & fees

Oct 25 - Oct 26

A long, ornate hallway with marble walls and a patterned floor, leading to a set of double doors.

A modern hotel room with a fireplace, a flat-screen TV, a sofa, and a bed.

A spacious indoor area with wooden flooring, multiple tables and chairs, a central bar area, and large windows allowing natural light.

A spacious lobby with a central seating area, large columns, and a chandelier.

14. Hotel at the Lafayette Trademark Collection by Wyndham

Buffalo Theater District, 1.6 km from Roswell Park Cancer Institute

Angela

P9,719

P11,347 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with a bed, a TV, a desk, a chair, and a sofa.

A buffet with various food items, including omelets and other dishes, served in metal trays.

A modern hotel room with a wooden dresser, a flat-screen TV, a kitchenette, a blue sofa, and a small table.

A coffee station with two coffee makers, a coffee dispenser, and various coffee cups and containers.

15. Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Buffalo Theater District, 1.1 km from Roswell Park Cancer Institute

Charles

P9,360

P10,928 total

includes taxes & fees

Oct 18 - Oct 19

An indoor swimming pool with clear glass walls, a wooden wall, and a view of buildings outside.

A restaurant with multiple tables and chairs, large windows with curtains, and a chandelier.

A hotel room with a sofa set, a small coffee table, a TV, and a lamp.

A Hyatt Regency hotel with a large entrance, a statue of a bull, and a landscaped garden with various plants.

16. Hyatt Regency Buffalo / Hotel and Conference Center

Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute

Joseph

P8,602

P10,043 total

includes taxes & fees

Oct 25 - Oct 26

A modern hotel with a curved glass facade, a central staircase, and a well-lit interior.

A conference room with two chairs and a table, large windows with a city view, and a patterned carpet.

A modern hotel room with a dining area, a large bed, and a view of the city.

A modern bar area with seating, a counter with bottles, and a large window.

17. Embassy Suites Buffalo

Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute

Michelle

P11,160

P13,029 total

includes taxes & fees

Oct 25 - Oct 26

A lobby with a staircase, seating area, and a view of the outdoors.

A bathroom with a toilet, sink, and shower curtain.

A hotel room with two beds, a desk, a television, and a window.

A hotel with a classic brick facade, a glass entrance, and flags.

18. Lenox Hotel and Suites

Allentown, 0.8 km from Roswell Park Cancer Institute

Thomas

P6,920

P7,941 total

includes taxes & fees

Oct 26 - Oct 27

A rooftop terrace with wicker furniture, a bar area, and a view of the cityscape.

A modern living room with a large window, a flat-screen TV, a sofa, a coffee table, and a patterned rug.

A bar area with a circular bar counter, multiple hanging light fixtures, and bar stools.

A modern cafe with round tables and chairs, a bar area, and a neon sign.

19. Aloft by Marriott Buffalo Downtown

Buffalo Theater District, 0.8 km from Roswell Park Cancer Institute

Anthony T

P13,770

P16,077 total

includes taxes & fees

Nov 8 - Nov 9

A dining area with a wooden table set for four, surrounded by chairs. There is a kitchen area with cabinets and appliances in the background.

A kitchen with wooden cabinets, a dishwasher, and a dining area with a table and chairs.

A bedroom with a bed, bedside lamps, a nightstand, a window with curtains, and wall art.

A kitchen with wooden cabinets, stainless steel appliances, and a red toaster.

20. 4 Mi to Dtwn: Family Home in Buffalo

Masten Park, 1.6 km from Roswell Park Cancer Institute

P18,658

P33,050 total

includes taxes & fees

Oct 13 - Oct 14

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Compare popular hotels close to Roswell Park Cancer Institute

Property	Property class	Guest rating
InnBuffalo off Elmwood	10.0 Exceptional 224 reviews	View
Buffalo Harmony House	10.0 Exceptional 56 reviews	View
The Edward Hotel	9.6 Exceptional 268 reviews	View
Buffalo Marriott at LECOM HARBORCENTER	9.4 Exceptional 984 reviews	View
The Mansion On Delaware Ave	9.4 Exceptional 1,005 reviews	View

Top Roswell Park Cancer Institute Hotel Reviews

The Mansion On Delaware Ave

8/10 Good

"Wonderful staff and wonderful building. My wife felt the breakfasts were some of the best breakfast dishes she’s had at any hotel or cafe. The reason I rated 4 instead of 5 stars is because the mattress wasn’t particularly comfortable and the soap/shampoo didn’t feel like it totally cleaned. Location gave excellent walking, running, and driving access, and free parking made having a car in the city very easy. I would stay here again without second thought!"

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

10/10 Excellent

"The room was very clean and nice. Walking distance to just about most of the places we wanted to visit a good place to stay."

Buffalo Guesthouse

10/10 Excellent

"Comfy beds and friendly environment."

Wyndham Garden Buffalo Downtown

8/10 Good

"Breakfast was fine. They tried to give variety throughout the week. Room was clean but could use a little more detail. Staff was very helpful when I couldn't find my reservation. With their help, they finally found it without it being a bother. Prentiss was also very courteous at breakfast. He was willing to please. Rooms were quiet depending on jour neighbors."

Lenox Hotel and Suites

10/10 Excellent

"Enjoyed our stay"

Hilton Garden Inn Buffalo Downtown

8/10 Good

"I didn't like that it was cashless. Also the lobby coffee, while cheap, was not good."

Hampton Inn & Suites Buffalo Downtown

10/10 Excellent

"Clean Comfortable Good breakfast"

The Westin Buffalo

10/10 Excellent

"."

Curtiss Hotel, an Ascend Collection Hotel

10/10 Excellent

"Loved it, we actually rerouted our return trip home to stay here again :)"

Other attractions near Roswell Park Cancer Institute

Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site

8.2/10 (144 reviews)

You can browse the exhibits at Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site, a museum with a storied past, during your trip to Buffalo. Experience the area's entertainment choices and acclaimed theater scene.

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Studio Arena Theater

Enjoy a performance at Studio Arena Theater, a storied theater in Buffalo. Experience the area's great live music and entertainment choices.

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Shea's 710 Theatre

You can enjoy a show at Shea's 710 Theatre during your stay in Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Town Ballroom

You can make plans for a show at Town Ballroom during your trip to Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Trinity Episcopal Church

You can learn about the history of Buffalo with a stop at Trinity Episcopal Church. Experience the great live music or attend a sporting event in this family-friendly area.

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Alleyway Theatre

You can make plans for a show at Alleyway Theatre during your stay in Buffalo. Experience the acclaimed theater scene and great live music in this family-friendly area.

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The 9th Ward

You can make plans for a show at The 9th Ward during your trip to Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Asbury Hall at Babeville

You can make plans for a show at Asbury Hall at Babeville during your stay in Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Frequently asked questions

What's the area like around Roswell Park Cancer Institute?

Roswell Park Cancer Institute is located in a historic area of Buffalo known for its popular theater scene. If you're looking for a convenient place to stay, check out the 71 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay close to Roswell Park Cancer Institute?

Adjacent to Roswell Park Cancer Institute, Wyndham Garden Buffalo Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a 24-hour fitness center. Other good choices close by include Hyatt Regency Buffalo / Hotel and Conference Center and Buffalo Guesthouse.

How many hotels will I find near Roswell Park Cancer Institute?

Expedia has 71 hotels and other accommodations within a mile from Roswell Park Cancer Institute.

If I need to cancel the hotel reservation for my stay near Roswell Park Cancer Institute, will I receive a refund?

Yes! Most hotel reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, it may still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then you can use the "fully refundable" filter to review the top deals on offer near Roswell Park Cancer Institute.

What can I see and do near Roswell Park Cancer Institute?

You might want to spend some time browsing the exhibits at Buffalo Museum of Science, Buffalo and Erie County Naval and Military Park, or Buffalo AKG Art Museum. Statler Tower, Buffalo Central Terminal, and Peace Bridge are monuments to see when you're exploring the area around Roswell Park Cancer Institute. You can catch a show at Kleinhans Music Hall, Town Ballroom, and Road Less Traveled Productions.

How can I get to Roswell Park Cancer Institute?

With so many transportation options, seeing all of the area near Roswell Park Cancer Institute is easy. Take advantage of metro transit at Fountain Plaza Station, Lafayette Square Station, and Church Station. If you're taking a train into town, Buffalo-Exchange Street Station is the closest stop to Downtown Buffalo.

Hotels near Roswell Park Cancer Institute

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for Roswell Park Cancer Institute hotels

1. InnBuffalo off Elmwood

2. Buffalo Harmony House

3. The Edward Hotel

4. Buffalo Marriott at LECOM HARBORCENTER

5. The Mansion On Delaware Ave

6. Buffalo Guesthouse

7. Curtiss Hotel, an Ascend Collection Hotel

8. Wyndham Garden Buffalo Downtown

9. The Westin Buffalo

10. Courtyard Buffalo Downtown / Canalside

11. Best Western on the Avenue

12. Hampton Inn & Suites Buffalo Downtown

13. Hilton Garden Inn Buffalo Downtown

14. Hotel at the Lafayette Trademark Collection by Wyndham

15. Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

16. Hyatt Regency Buffalo / Hotel and Conference Center

17. Embassy Suites Buffalo

18. Lenox Hotel and Suites

19. Aloft by Marriott Buffalo Downtown

20. 4 Mi to Dtwn: Family Home in Buffalo

Compare popular hotels close to Roswell Park Cancer Institute

Top Roswell Park Cancer Institute Hotel Reviews

The Mansion On Delaware Ave

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Buffalo Guesthouse

Wyndham Garden Buffalo Downtown

Lenox Hotel and Suites

Hilton Garden Inn Buffalo Downtown

Hampton Inn & Suites Buffalo Downtown

The Westin Buffalo

Curtiss Hotel, an Ascend Collection Hotel

Other attractions near Roswell Park Cancer Institute

Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site

Studio Arena Theater

Shea's 710 Theatre

Town Ballroom

Trinity Episcopal Church

Alleyway Theatre

The 9th Ward

Asbury Hall at Babeville

Frequently asked questions