Calle 50

A cityscape with modern skyscrapers and lush green trees.
A cityscape with modern skyscrapers, including a distinctive twisting tower.
A modern, spiraling skyscraper with a unique design, surrounded by other buildings in an urban setting.
A harbor with several boats docked in the foreground and a city skyline in the background.
A city skyline with tall buildings and palm trees.

Tours & day trips

See all 473 activities
City Sightseeing Panama City Hop-On Hop-Off Bus Tour

City Sightseeing Panama City Hop-On Hop-Off Bus Tour

Activity duration is 1 day
8.0 out of 10 with 177 reviews
Free cancellation available
Price is P 1,822 per adult
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Private & custom tours

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Embera Village Excursion plus Waterfalls experience private Tour

Embera Village Excursion plus Waterfalls experience private Tour

Activity duration is 5 hours
9.4 out of 10 with 17 reviews
Free cancellation available
Price is P 7,290 per adult
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Adventure & outdoor

See all 118 activities
Visit San Blas Paradise: Day Tour to 4 Islands with Lunch & Drink

Visit San Blas Paradise: Day Tour to 4 Islands with Lunch & Drink

Activity duration is 14 hours
8.8 out of 10 with 65 reviews
Free cancellation available
Price is P 6,378 per adult
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Wildlife & nature

See all 54 activities
From Panama City: Monkey Islands Tour on Gatun Lake

From Panama City: Monkey Islands Tour on Gatun Lake

Activity duration is 4 hours and 30 minutes
9.4 out of 10 with 66 reviews
Free cancellation available
Price is P 1,822 per adult
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Classes & workshops

See all 25 activities
Learn about Panama cocoa and create your own chocolate bar

Learn about Panama cocoa and create your own chocolate bar

Activity duration is 1 hour and 15 minutes
9.4 out of 10 with 192 reviews
Free cancellation available
Price is P 2,734 per adult
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Stay near popular Calle 50 attractions

Calle 50

You can find out about the history of Panama City with a trip to Calle 50. Discover the area's shops, or seek out its local tours.
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Top Hotel Deals

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Hotel Riu Plaza Panama
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
Megapolis Hotel Panamá
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4 out of 5
Via Israel Multiplaza Pacific Mall Panama City Panama
Courtyard by Marriott Panama Multiplaza Mall
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina Panama City Panama
Principe Hotel and Suites
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi Panama City
Waymore Hotel Spa & Casino
Hospedium Princess Hotel Panama

Hospedium Princess Hotel Panama

3.5 out of 5
Calle 53 Marbella y Avenida 5a B sur Panama City Panama
Hospedium Princess Hotel Panama
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro Panama City Panama
Decapolis Hotel Panama City
The District Hotel Panama

The District Hotel Panama

3 out of 5
C. Eusebio A. Morales Panama City Provincia de Panamá
The District Hotel Panama
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
Las Americas Golden Tower Panama
See all 1,771 properties in Calle 50
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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