Hotels near Mayo Clinic

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Our top choices for Mayo Clinic hotels

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Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
3.5 star property
Downtown Rochester, 0.3 km from Mayo Clinic
9.6 out of 10, Exceptional, (547)
"Very courteous staff, loved the valet guy!"
United States
Jean
The price is P10,068
P11,591 total
includes taxes & fees
Jan 10 - Jan 11, 2026
Hilton Rochester Mayo Clinic Area
Property amenity
TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
Downtown Rochester, 0.4 km from Mayo Clinic
9.6 out of 10, Exceptional, (483)
"Room was large, clean, beds were comfortable. Downstairs cafe and seating areas were very comfortable."
United States
Ann
The price is P7,461
P8,589 total
includes taxes & fees
Jan 2 - Jan 3, 2026
TownePlace Suites by Marriott Rochester Mayo Clinic Area
View from property
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
2.5 star property
Kutzky Park, 1.8 km from Mayo Clinic
9.6 out of 10, Exceptional, (680)
"Good place to stay when traveling to Mayo apots"
United States
Carolyn
The price is P5,757
P6,628 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Terrace/patio
The Berkman

The Berkman

The Berkman
3.0 star property
Folwell, 1.4 km from Mayo Clinic
9.6 out of 10, Exceptional, (372)
"Staff was great, as was the room."
United States
Scott
The price is P9,829
P11,428 total
includes taxes & fees
Dec 31 - Jan 1, 2026
The Berkman
Courtyard
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
4.0 star property
Kutzky Park, 1 km from Mayo Clinic
9.4 out of 10, Exceptional, (968)
"Room was amazing and the staff was very courteous. "
United States
Jennifer
The price is P6,697
P7,828 total
includes taxes & fees
Jan 2 - Jan 3, 2026
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Terrace/patio
Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
2.6 km from Mayo Clinic
9.6 out of 10, Exceptional, (887)
"Great stay,clean and friendly"
United States
Janet
The price is P7,178
P8,263 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Home2 Suites by Hilton Rochester Mayo Clinic Area
Terrace/patio
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
3.0 star property
Downtown Rochester, 0.5 km from Mayo Clinic
9.2 out of 10, Wonderful, (1006)
"Quick and easy check-in, walkable area and nice breakfast and accomodations. Would stay again!"
United States
Elizabeth
The price is P7,578
P8,725 total
includes taxes & fees
Dec 30 - Dec 31
Hyatt House Rochester/Mayo Clinic Area
BBQ/picnic area
Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South
3.0 star property
2.6 km from Mayo Clinic
9.6 out of 10, Exceptional, (254)
"Rooms were clean staff was courteous. "
United States
Michael
The price is P7,520
P8,657 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Residence Inn by Marriott Rochester Mayo Clinic Area South
Courtyard
Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG
3.0 star property
Kutzky Park, 1 km from Mayo Clinic
9.4 out of 10, Exceptional, (425)
"This was an amazing find in Rochester. Looking forward to staying here again. "
United States
Kellie
The price is P7,578
P8,842 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Staybridge Suites Rochester - Mayo Clinic Area by IHG
Fridge, microwave, oven, stovetop
Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham
3.0 star property
Downtown Rochester, 0.3 km from Mayo Clinic
9.2 out of 10, Wonderful, (168)
"Great staff, clean room, spacious kitchen and living room."
United States
silvia
The price is P9,254
P10,653 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Broadway Plaza, Trademark Collection by Wyndham
Exterior
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
Kutzky Park, 1.4 km from Mayo Clinic
9.2 out of 10, Wonderful, (773)
"Clean room and housekeeping service was excellent"
United States
Dawn
The price is P4,935
P5,681 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Terrace/patio
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
3.0 star property
Kutzky Park, 1.4 km from Mayo Clinic
9.2 out of 10, Wonderful, (478)
"Everything was exceptional as usual!"
United States
Colin
The price is P6,600
P7,598 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
Desk, iron/ironing board, free WiFi, bed sheets
Brentwood Inn & Suites

Brentwood Inn & Suites

Brentwood Inn & Suites
2.5 star property
Downtown Rochester, 0.3 km from Mayo Clinic
8.8 out of 10, Excellent, (1004)
"Convenient, clean location and friendly staff"
United States
Kaushika
The price is P6,609
P7,608 total
includes taxes & fees
Dec 30 - Dec 31
Brentwood Inn & Suites
Exterior
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
Downtown Rochester, 0.3 km from Mayo Clinic
8.8 out of 10, Excellent, (893)
"Room was clean and comfortable Staff courteous Comfortable beds Great restaurant"
United States
Matney
The price is P4,700
P5,411 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Breakfast served
Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN
3.0 star property
Downtown Rochester, 0.3 km from Mayo Clinic
8.8 out of 10, Excellent, (854)
"Everything was wonderful! Helpful, friendly staff, great location, nice amenities."
United States
kristi
The price is P6,288
P7,239 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hilton Garden Inn Rochester Downtown, MN
Front of property
Aspen Suites

Aspen Suites

Aspen Suites
3.0 star property
1.2 km from Mayo Clinic
9.0 out of 10, Wonderful, (695)
"Room was clean and inviting and staff always willing to help"
United States
Maria del Carmen
The price is P9,693
P11,717 total
includes taxes & fees
Jan 16 - Jan 17, 2026
Aspen Suites
Exterior
Candlewood Suites Rochester Mayo Clinic Area by IHG

Candlewood Suites Rochester Mayo Clinic Area by IHG

Candlewood Suites Rochester Mayo Clinic Area by IHG
2.5 star property
2.6 km from Mayo Clinic
9.2 out of 10, Wonderful, (455)
"The staff checking in and out were helpful and friendly. The room was clean, comfortable, and quiet. "
United States
Allison
The price is P5,698
P6,560 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Candlewood Suites Rochester Mayo Clinic Area by IHG
Terrace/patio
Hampton Inn Rochester-South

Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.5 star property
2.9 km from Mayo Clinic
9.0 out of 10, Wonderful, (1004)
"We had a wonderful stay!"
United States
Sarah
The price is P4,744
P5,461 total
includes taxes & fees
Jan 24 - Jan 25, 2026
Hampton Inn Rochester-South
Free daily full breakfast
Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
2.0 star property
3 km from Mayo Clinic
9.0 out of 10, Wonderful, (906)
"Staff was great. Great value for the cost. "
United States
Damon
The price is P4,062
P4,677 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Econo Lodge Mayo Clinic Area
Exterior
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
2.5 star property
Kutzky Park, 1.6 km from Mayo Clinic
8.8 out of 10, Excellent, (765)
"Clean room, friendly staff. The only minus is the lighting in the bathroom, way too dim. "
United States
Stacy
The price is P5,581
P6,425 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Mayo Clinic Hotel Reviews

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

10/10 Excellent
"Everyone was so friendly and accommodating. Clean and quiet place."
Kimie 6-night trip
Posted 1 day ago
EVEN Hotel Rochester - Mayo Clinic Area by IHG

Hotels near other Mayo Clinic attractions

Soldiers Field Veterans Memorial

4.5/5 (30 reviews)
You can learn about the history of Rochester with a visit to Soldiers Field Veterans Memorial. Attend a sporting event or simply visit the area's shops.
See properties

Plummer Building

You can find out about the history of Rochester when you stop by Plummer Building.
See properties

Frequently asked questions

What's the area like around Mayo Clinic?
Mayo Clinic is located in a welcoming area of Rochester known for its major shopping area. If you're looking for a convenient place to stay, check out the 159 hotels and other accommodations you'll find within a mile.
What's the best place to stay close to Mayo Clinic?
Adjacent to Mayo Clinic, Kahler Grand Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers 2 restaurants and an indoor pool. Other good options close by include Kahler Inn and Suites - Mayo Clinic Area and Hotel Indigo Rochester – Mayo Clinic Area by IHG.
How many hotels will I be able to find near Mayo Clinic?
Expedia has 159 hotels and other accommodations within a mile from Mayo Clinic.
If I need to cancel the hotel reservation for my stay near Mayo Clinic, will I receive a refund?
Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best deals near Mayo Clinic.
What can I see and do near Mayo Clinic?
You'll want to browse the exhibits at Mayowood Mansion and History Center of Olmsted County. Learn about local history at Assisi Heights and Plummer House. You can enjoy live performances at Rochester Civic Theater and Marcus Rochester Cinema.