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Hotels near Mayo Clinic

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Our top choices for Mayo Clinic hotels

A swimming pool with a glass ceiling, a neon sign for the KAFFLER HOTEL, and a view of the city skyline at dusk.
A hotel entrance with a modern design, large windows, and a sign indicating it's a Grand Hotel.
A hotel room with a large bed, a desk, a chair, a microwave, and a framed picture on the wall.
A banquet hall with round tables, chairs, chandeliers, and a fireplace.

1. Kahler Grand Hotel

Kahler Grand Hotel
Downtown Rochester, 0.1 km from Mayo Clinic
United States
Heidi
P8,378
P9,645 total
includes taxes & fees
Oct 1 - Oct 2
Kahler Grand Hotel
A poolside area with wicker chairs and potted plants, a tiled floor, and a clear view of the pool.
A hotel room with a sofa, two beds, a large window, and a framed artwork on the wall.
A modern building with large windows and a parking lot.
A reception area with a wooden reception desk, a clock, and a wall-mounted display.

2. Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area
Downtown Rochester, 0.2 km from Mayo Clinic
United States
Dana
P8,940
P10,293 total
includes taxes & fees
Oct 3 - Oct 4
Kahler Inn and Suites - Mayo Clinic Area
A spacious outdoor dining area with modern furniture and large windows offering views of the city.
A modern hotel room with a large bed, a sofa, a small table, a desk, and a wardrobe.
A modern interior with a wooden ceiling, a large black shelving unit, and a refrigerator stocked with beverages.
A reception desk with a modern design, featuring a wooden panel and a wall adorned with framed botanical artwork.

3. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
Downtown Rochester, 0.4 km from Mayo Clinic
United States
thomas
P6,685
P7,696 total
includes taxes & fees
Oct 24 - Oct 25
Hotel Indigo Rochester – Mayo Clinic Area by IHG
An outdoor patio area with yellow umbrellas, wicker furniture, and a sign for Centerstone Plaza Hotel.
A garden with a water feature, rocks, and yellow umbrellas.
A modern reception area with a wooden reception desk, glass pendant lights, and a long hallway with seating.
A restaurant interior with wooden tables, chairs, and a stone wall.

4. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Historic Southwest, 0.6 km from Mayo Clinic
United States
Carrie
P6,738
P7,758 total
includes taxes & fees
Oct 2 - Oct 3
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
A modern living room with a flat-screen TV, a fireplace, comfortable seating, and a large window with a city view.
A spacious lobby with modern furniture, a spiral staircase, and large windows offering views of the outdoors.
A modern indoor swimming pool with seating areas and a city view.
A modern hotel entrance with a glass facade, illuminated signage, and a covered walkway.

5. Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
Downtown Rochester, 0.3 km from Mayo Clinic
United States
Raymond
P11,219
P12,916 total
includes taxes & fees
Oct 17 - Oct 18
Hilton Rochester Mayo Clinic Area
A modern indoor patio with a fire feature, seating, and large windows.
A modern living room with a fireplace, large windows, and a flat-screen TV mounted on the wall.
A modern interior with a seating area, a bookshelf, and a window with a view of trees.
A reception area with a curved reception desk, wooden shelving, and a green moss wall with the text "I ♥ EVEN".

6. EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
Kutzky Park, 1 km from Mayo Clinic
United States
Brooke
P7,622
P9,619 total
includes taxes & fees
Oct 2 - Oct 3
EVEN Hotel Rochester - Mayo Clinic Area by IHG
An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.
A modern Hyatt House hotel with a prominent 'Hyatt House' sign, multiple floors, and a parking garage.
A modern bar area with seating and a counter.
A modern dining area with round tables and chairs, a large painting on the wall, and a flat-screen TV mounted above a geometric-patterned wall.

7. Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
Downtown Rochester, 0.5 km from Mayo Clinic
United States
Kathy
P7,372
P8,487 total
includes taxes & fees
Oct 17 - Oct 18
Hyatt House Rochester/Mayo Clinic Area
A coffee shop interior with a wooden counter, menu boards, and seating area.
A hotel exterior with a 'Townplace Suites' sign, outdoor seating area, and 'OPEN' signage.
An outdoor seating area with tables and chairs, a neon sign, and flower arrangements.

8. TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
Kutzky Park, 0.4 km from Mayo Clinic
United States
Hafsa
P8,559
P9,854 total
includes taxes & fees
Oct 2 - Oct 3
TownePlace Suites by Marriott Rochester Mayo Clinic Area
A room with a fireplace, two leather armchairs, a sofa, and a large window providing a view of the outdoors.
A long, narrow hotel corridor with a carpeted floor, light fixtures along the walls, and a ceiling with recessed lighting.
A reception area with a curved counter, ceiling lights, and a potted plant.
A hotel room with a bed, a sink, a microwave, and a window with curtains.

9. Brentwood Inn & Suites

Brentwood Inn & Suites
Downtown Rochester, 0.3 km from Mayo Clinic
United States
Daniel
P5,857
P6,743 total
includes taxes & fees
Oct 1 - Oct 2
Brentwood Inn & Suites
A spacious hotel lobby with multiple seating areas, including sofas and round tables, and a large dining area with yellow chairs.
A reception area with two counters, a patterned wall, and a wooden floor.
A hotel room with a blue sofa, a wooden bench, a small table with a lamp, a painting of a flower, and a kitchenette in the background.
A grocery store with refrigerated and frozen sections, shelves stocked with snacks, and a variety of beverages.

10. Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN
Downtown Rochester, 0.3 km from Mayo Clinic
United States
John
P7,121
P8,198 total
includes taxes & fees
Oct 23 - Oct 24
Hilton Garden Inn Rochester Downtown, MN
A spacious living area with a modern staircase, leather sofas, and contemporary lighting.
A modern pool table in a spacious, well-lit room with large windows and a bar area.
An outdoor seating area with blue sofas and wicker chairs, a wooden table, and green ottomans on a tiled patio.
A modern interior with a large dining table, sofas, and a kitchen area.

11. The Berkman

The Berkman
Folwell, 1.4 km from Mayo Clinic
United States
Kathleen
P11,246
P13,076 total
includes taxes & fees
Oct 2 - Oct 3
The Berkman
A modern building with large glass windows and indoor plants.
A spacious indoor area with multiple seating arrangements and a pool.
A clean, well-lit food service area with a 'Market To Go!' sign, refrigerated display cases, and a variety of packaged goods.
A modern hotel lobby with a large dining table, wicker chairs, a sofa, and a hanging green plant.

12. Marriott Rochester Mayo Clinic

Marriott Rochester Mayo Clinic
Downtown Rochester, 0.2 km from Mayo Clinic
United States
Jeff
P14,932
P17,190 total
includes taxes & fees
Oct 10 - Oct 11
Marriott Rochester Mayo Clinic
An indoor swimming pool with clear water, wooden flooring, and a ceiling with wooden beams and lights.
A café with multiple tables and chairs, a kitchen area with appliances, and a clock on the wall.
A room with a TV mounted on the wall, a wooden table, and two patterned armchairs.
A gym with treadmills, an elliptical, and a water station.

13. Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area
Kutzky Park, 1.6 km from Mayo Clinic
United States
Rick
P4,461
P5,135 total
includes taxes & fees
Sep 28 - Sep 29
Med City Inn & Suites - Mayo Clinic Area
An outdoor terrace with tables and chairs, a large umbrella, and a view of a modern building with string lights.
A modern kitchen with stainless steel appliances, a built-in oven, and a variety of food items on the counter.
A modern hotel room with a fireplace, a sofa, a TV, and a large window with curtains.

14. Residence Inn by Marriott Rochester Mayo Clinic Area

Residence Inn by Marriott Rochester Mayo Clinic Area
Downtown Rochester, 0.2 km from Mayo Clinic
United States
Greg
P10,558
P12,156 total
includes taxes & fees
Oct 11 - Oct 12
Residence Inn by Marriott Rochester Mayo Clinic Area
A modern outdoor seating area with a built-in fireplace, two wooden chairs, a table, and a sofa.
A hotel room with a kitchenette, a bed, a sofa, a small table, and a window with curtains.
A modern kitchen with a central island, bar stools, and pendant lighting. A living area with a sofa, ottoman, and a view of the outdoors is visible.
A modern interior with a dining area, a kitchen, and a pantry stocked with snacks.

15. Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG
Kutzky Park, 1 km from Mayo Clinic
United States
Sheri
P6,685
P7,821 total
includes taxes & fees
Oct 25 - Oct 26
Staybridge Suites Rochester - Mayo Clinic Area by IHG
A hotel entrance with a stone facade, a glass door, and a metal roof structure.
A spa area with a hot tub, exercise equipment, and a seating area with chairs and a table.
An outdoor patio area with brick walls, a large arched window, and outdoor seating.
A hotel lobby with striped armchairs, a sofa, a fireplace, and a clock on the wall.

16. Aspen Suites

Aspen Suites
1.2 km from Mayo Clinic
United States
Dana
P8,857
P10,706 total
includes taxes & fees
Oct 2 - Oct 3
Aspen Suites
A lobby with leather chairs, a reception desk, a TV, and a coffee station.
A hotel with a modern building featuring a prominent sign, a covered entrance, and a parking area.
An outdoor patio with tables and chairs, a sign for Aspen Suites, and a building in the background.

17. Aspen Select

Aspen Select
Kutzky Park, 1.2 km from Mayo Clinic
United States
Sue
P8,059
P9,742 total
includes taxes & fees
Oct 2 - Oct 3
Aspen Select
A modern hotel lobby with multiple seating areas, including a central dining table with chairs, a bar area, and a seating section with cushioned chairs.
A hotel reception desk with a modern design, a clock, and a digital screen.
A modern lounge area with a curved sofa, a round table, and a seating area with chairs.
A modern hotel room with a large bed, two bedside tables, and built-in lighting.

18. SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
Kutzky Park, 1.1 km from Mayo Clinic
United States
Jackie
P7,253
P8,350 total
includes taxes & fees
Oct 4 - Oct 5
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
An outdoor patio with a brick floor, stone fireplace, and wooden pergola.
A modern hotel lobby with a stone wall fireplace, comfortable seating, and a chandelier.
A gym with exercise equipment, a clock, and a window with blinds.
An indoor swimming pool with clear pool rules posted on the wall, a lifeguard chair, and a pool lift sign.

19. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
Kutzky Park, 1.4 km from Mayo Clinic
United States
Lin
P7,121
P8,198 total
includes taxes & fees
Oct 24 - Oct 25
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
View all properties

Compare popular hotels close to Mayo Clinic

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A coffee shop interior with a wooden counter, menu boards, and seating area.
TownePlace Suites by Marriott Rochester Mayo Clinic Area
9.6
Exceptional
562 reviews
View
An outdoor patio area with a concrete floor, wooden fence, and string lights.
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
9.6
Exceptional
740 reviews
View
An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.
Home2 Suites by Hilton Rochester Mayo Clinic Area
9.6
Exceptional
1,004 reviews
View
A swimming pool with clear blue water, surrounded by lounge chairs and a view of residential buildings through large windows.
Residence Inn by Marriott Rochester Mayo Clinic Area South
9.6
Exceptional
311 reviews
View
A spacious living area with a modern staircase, leather sofas, and contemporary lighting.
The Berkman
9.6
Exceptional
441 reviews
View

Top Mayo Clinic Hotel Reviews

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

8/10 Good
"Great price, my child enjoyed the pool area, room was comfortable, staff was great!"
Jamia 1-night trip
Posted 3 hours ago
AmericInn by Wyndham Rochester Near Mayo Clinic
Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG

10/10 Excellent
".,mb;jkb;kjbn.,m vktydel;u6yf;iuhg"
Eric 2-night trip
Posted 3 hours ago
Staybridge Suites Rochester - Mayo Clinic Area by IHG
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

8/10 Good
"Quiet and comfortable."
Jean 1-night trip
Posted 7 hours ago
Med City Inn & Suites - Mayo Clinic Area
Brentwood Inn & Suites

Brentwood Inn & Suites

10/10 Excellent
"Got in pretty late, but the front desk staff were very friendly and accommodating. My room was clean, bed was very comfortable. I also enjoyed the continental breakfast and coffee in the morning."
Maria 1-night trip
Posted 7 hours ago
Brentwood Inn & Suites
Kahler Grand Hotel

Kahler Grand Hotel

10/10 Excellent
"Staff very helpful. Essex restaurant very good. Rooms small. Overall good."
Kay 2-night trip
Posted 15 hours ago
Kahler Grand Hotel
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

10/10 Excellent
"Na"
Badri 3-night trip
Posted 16 hours ago
Hyatt House Rochester/Mayo Clinic Area
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

8/10 Good
"The hotel is clean, comfortable, and offers easy parking. Mayo Clinic is within walking distance (half mile). The staff is helpful and friendly. Bonus: the pool and hot tub area is very relaxing!"
Rachel 1-night trip
Posted 1 day ago
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

10/10 Excellent
"We had a great night of sleep after a long day at Mayo. The bed was comfortable. Hotel was clean and staff was helpful and very friendly. The breakfast was good with many options."
Naomi 1-night trip
Posted 2 days ago
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

8/10 Good
"Staff at check in,close to mayo"
Bernice 1-night trip
Posted 2 days ago
Kahler Inn and Suites - Mayo Clinic Area

Frequently asked questions

What's the area like around Mayo Clinic?
Mayo Clinic is located in a welcoming area of Rochester known for its major shopping area. If you're looking for a convenient place to stay, check out the 152 hotels and other accommodations you'll find within a mile.
What's the best place to stay close to Mayo Clinic?
Adjacent to Mayo Clinic, Kahler Grand Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers 2 restaurants and an indoor pool. Other good options close by include Kahler Inn and Suites - Mayo Clinic Area and Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area.
How many hotels will I be able to find near Mayo Clinic?
Expedia has 152 hotels and other accommodations within a mile from Mayo Clinic.
If I need to cancel the hotel reservation for my stay near Mayo Clinic, will I receive a refund?
Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best deals near Mayo Clinic.
What can I see and do near Mayo Clinic?
You'll want to browse the exhibits at Mayowood Mansion and History Center of Olmsted County. Learn about local history at Plummer House and Assisi Heights. You can enjoy live performances at Rochester Civic Theater and Marcus Rochester Cinema.