New Madrid County Hotels: Find & Book Cheap Hotel Deals in New Madrid County

Top Cities in New Madrid County

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A cannon on a brick platform by a river, with a steamboat in the background.

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Our top choices for New Madrid County hotels

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

1. Drury Inn & Suites Sikeston, MO

Sikeston

Scott

P6,789 total

includes taxes & fees

Oct 18 - Oct 19

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

2. Hampton Inn Sikeston

Sikeston

Carolyn

P7,530 total

includes taxes & fees

Oct 18 - Oct 19

A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

3. Best Western Plus Sikeston I-55

Sikeston

Shelley

P6,071 total

includes taxes & fees

Nov 1 - Nov 2

A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

4. Days Inn and Suites by Wyndham Sikeston

Sikeston

David

P4,747 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.

5. Super 8 by Wyndham Sikeston/Miner Area

Sikeston

Marcia

P4,090 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.

6. Holiday Inn Express & Suites Sikeston Southwest by IHG

Sikeston

Melissa

P6,501 total

includes taxes & fees

Nov 8 - Nov 9

An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

7. Fairfield Inn & Suites by Marriott Sikeston

Sikeston

Allen

P7,216 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

8. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Sikeston

Craig

P4,976 total

includes taxes & fees

Oct 12 - Oct 13

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

9. Country Yard Inn and Suite

Sikeston

William

P4,367 total

includes taxes & fees

Oct 12 - Oct 13

A modern hotel room with a large bed, bedside tables, a nightstand, a wall-mounted lamp, a window with a view of a road, and a wall-mounted air conditioner.

10. Super 8 By Wyndham Marston

Marston

Brenda

P4,022 total

includes taxes & fees

Oct 21 - Oct 22

A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.

11. Comfort Inn & Suites Sikeston I-55

Sikeston

Kathryn

P6,619 total

includes taxes & fees

Nov 11 - Nov 12

12. TownePlace Suites by Marriott Sikeston

Sikeston

Rubin

P7,226 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with two beds, a television, a desk, and a mirror.

13. Travel Inn Marston I-55 by Hotel O

Marston

Frank

P3,428 total

includes taxes & fees

Nov 9 - Nov 10

A bedroom with a bed, bedside table, lamp, and a view of the bathroom.

14. OYO Malden Airport Inn

Malden

James

A hotel room with a dark wooden desk, a television, a lamp, a chair, and a mirror on the wall.

15. Reelfoot Lake Inn

Tiptonville

Danny

P4,397 total

includes taxes & fees

Nov 1 - Nov 2

A cozy cabin-style room with a large L-shaped sectional sofa, a wooden ceiling, and a ladder leading to an upper level.

16. Close to Reelfoot Lake! Dog-friendly Retreat

Tiptonville

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Top New Madrid County Hotel Reviews

Hampton Inn Sikeston

10/10 Excellent

"Great place"

Days Inn and Suites by Wyndham Sikeston

8/10 Good

"We were traveling through and wanted a quiet clean place to sleep. This was quiet clean although it is a bit dated. Only issue with maintenance was the outlet in the bathroom did not work which did not bother us but it should be attended to. We actually had a suite so it was very spacious. It was about $30 less than other rooms that were available in the area so it was quite a value in my opinion."

The Farmstead Hotel

8/10 Good

"I was in town for a high school class reunion, and the property was conveniently located, and the room rate was very competitive with other hotels in the area. On the positive side, the front desk staff was superb. Friendly and extremely helpful throughout my stay. The only negative? Checking out on Sunday morning, I had to go across the street to the "main" hotel and drop off my key. After check-out time, there should be a desk clerk at the Farmstead as well. My only complaint came during check-in on Friday afternoon. The front desk handed me my key and I went to the room. It looked fine, except for the pile of dirty towels behind the door. So, they sent me to another room--same thing. The third room proved to be the charm; clean, comfortable and no dirty towels behind the door. Overall, I was pleased with the stay. It more than met my needs, despite a few glitches."

Room 1

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Top Cities in New Madrid County

Sikeston

New Madrid

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Our top choices for New Madrid County hotels

1. Drury Inn & Suites Sikeston, MO

2. Hampton Inn Sikeston

3. Best Western Plus Sikeston I-55

4. Days Inn and Suites by Wyndham Sikeston

5. Super 8 by Wyndham Sikeston/Miner Area

6. Holiday Inn Express & Suites Sikeston Southwest by IHG

7. Fairfield Inn & Suites by Marriott Sikeston

8. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

9. Country Yard Inn and Suite

10. Super 8 By Wyndham Marston

11. Comfort Inn & Suites Sikeston I-55

12. TownePlace Suites by Marriott Sikeston

13. Travel Inn Marston I-55 by Hotel O

14. OYO Malden Airport Inn

15. Reelfoot Lake Inn

16. Close to Reelfoot Lake! Dog-friendly Retreat

Top New Madrid County Hotel Reviews

Hampton Inn Sikeston

Century Casino & Hotel Caruthersville

Drury Inn & Suites Sikeston, MO

Reelfoot Lake Inn

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Holiday Inn Express & Suites Sikeston Southwest by IHG

Hampton Inn By Hilton Dexter

Days Inn and Suites by Wyndham Sikeston

The Farmstead Hotel

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Search New Madrid County Hotels

Change your mind

Treat yourself

Be picky

Top Cities in New Madrid County

Sikeston

New Madrid

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for New Madrid County hotels

1. Drury Inn & Suites Sikeston, MO

2. Hampton Inn Sikeston

3. Best Western Plus Sikeston I-55

4. Days Inn and Suites by Wyndham Sikeston

5. Super 8 by Wyndham Sikeston/Miner Area

6. Holiday Inn Express & Suites Sikeston Southwest by IHG

7. Fairfield Inn & Suites by Marriott Sikeston

8. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

9. Country Yard Inn and Suite

10. Super 8 By Wyndham Marston

11. Comfort Inn & Suites Sikeston I-55

12. TownePlace Suites by Marriott Sikeston

13. Travel Inn Marston I-55 by Hotel O

14. OYO Malden Airport Inn

15. Reelfoot Lake Inn

16. Close to Reelfoot Lake! Dog-friendly Retreat

Top New Madrid County Hotel Reviews

Hampton Inn Sikeston

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