A historic stone fortress with a central dome and surrounding walls.

Luxury Hotels in Colon, Colón

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Check availability on Colon Luxury Hotels

Tonight
Oct 20 - Oct 21
Tomorrow
Oct 21 - Oct 22
This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1

Our top choices for Colon luxury hotels

A balcony with a table, chairs, and a view of a city skyline across a body of water.
A spacious lobby with high ceilings, modern furniture, and decorative lighting fixtures.
A hotel with a rooftop pool, lounge chairs, and a view of the sea.
A spacious living room with a high ceiling, large windows, and a decorative ceiling fan.

1. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
  • Indulge in colonial elegance at this Panama City gem featuring a full-service spa, outdoor pool, and gourmet dining.
P22,140
P24,354 total
includes taxes & fees
Nov 3 - Nov 4
Sofitel Legend Casco Viejo, Panama City
A poolside area with lounge chairs and a view of the ocean.
A modern hotel room with a large bed, a chair, a nightstand with a lamp, and a view of the cityscape at dusk.
A modern bathroom with a large bathtub, two sinks, and a glass-enclosed shower area with a city view.
A modern building with a symmetrical facade, multiple balconies, and a central atrium with lighting.

2. JW Marriott Panama

JW Marriott Panama
San Francisco
  • Unwind in opulent waterfront luxury with 4 pristine pools and ocean-view dining in Panama City.
P18,620
P20,482 total
includes taxes & fees
Nov 6 - Nov 7
JW Marriott Panama
A restaurant with multiple dining tables, chairs, and a central water feature.
A bar area with multiple seating options, a bar counter, and a fireplace.
A modern living room with a sofa, a coffee table, and a TV mounted on the wall.
A historic building with ornate stonework and a balcony with plants.

3. Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
Casco Viejo
  • Experience historic luxury in Panama's Casco Viejo district with 5 restaurants and a rooftop pool with spectacular views.
P16,542
P18,196 total
includes taxes & fees
Oct 21 - Oct 22
Hotel La Compañía Casco Antiguo
A hotel entrance with a central water feature, seating areas, and potted plants.
A pool with a central water feature, surrounded by seating areas and potted plants.
The entrance of The Santa Maria with a covered walkway and a view of the interior.
A spacious lobby with a wooden ceiling, a central wooden table surrounded by potted plants, and a marble wall with a large window in the background.

4. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
  • Elevate your Panama City escape with a Jack Nicklaus golf course, rejuvenating spa treatments, and poolside luxury at this 5-star retreat.
P19,671
P21,638 total
includes taxes & fees
Nov 8 - Nov 9
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
A modern hotel pool area with lounge chairs and a clear view of the ocean.
A spacious lobby with a large seating area, a glass display case with bottles, and a view of the city at night.
A modern bar area with seating and a view of the city.
A modern interior with a spiral staircase, a large window, and a seating area.

5. Hilton Panama

Hilton Panama
Bella Vista
  • Panama City sophistication meets relaxation with an attached winery, poolside dining, and a full-service spa offering couples' treatments.
P16,542
P18,196 total
includes taxes & fees
Nov 8 - Nov 9
Hilton Panama
A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.
A modern hotel room with a dining area, a TV, and a city view.
A hotel room with a bed, a TV, a desk, and a view of the cityscape through a window.
A spacious lobby with a central seating area, a chandelier, and a modern ceiling design.

6. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
Bella Vista
  • Exclusive Panama City escape offers lavish poolside retreats and gourmet dining experiences.
P7,548
P8,303 total
includes taxes & fees
Nov 3 - Nov 4
Hotel Riu Plaza Panama
A person seated at a bar with a drink, in a room with a teal accent wall and hanging lights.
An outdoor seating area with wicker chairs and tables, large windows offering a city view at dusk.
A modern interior with a decorative ceiling, a person in a white dress, and a blue-lit wall.
A modern building with a rooftop lounge area, large windows, and a balcony overlooking a cityscape.

7. Waldorf Astoria Panama

Waldorf Astoria Panama
Bella Vista
  • Panama City elegance at this Waldorf Astoria hotel with a full-service spa, outdoor pool, and refined dining in two upscale restaurants.
P16,542
P18,196 total
includes taxes & fees
Nov 7 - Nov 8
Waldorf Astoria Panama
A modern restaurant with large windows offering a city view, warm lighting, and contemporary furniture.
A modern hotel room with a large bed, a desk, a chair, and a view of the cityscape.
A high-rise building with a rooftop pool area, surrounded by other buildings.
A modern high-rise building with a prominent 'W' logo, surrounded by other buildings and a busy street at night.

8. W Panama

W Panama
Bella Vista
  • Lavish urban retreat offers 3 hot tubs, poolside luxury, and concierge services in Panama city.
P14,561
P16,017 total
includes taxes & fees
Nov 7 - Nov 8
W Panama
A spacious indoor area with high ceilings, large windows, and multiple dining tables.
A restaurant with brick walls, arched windows, and a variety of seating arrangements including tables and chairs.
A multi-story hotel with a central courtyard, balconies, and a view of the city skyline.
A white building with multiple balconies, large windows, and decorative railings.

9. American Trade Hotel

American Trade Hotel
Casco Viejo
  • A colonial gem in Panama City offering luxurious comfort, exquisite dining, and personalized service in a historic district.
P15,471
P17,018 total
includes taxes & fees
Nov 8 - Nov 9
American Trade Hotel
A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.
A spacious hotel lobby with modern furniture, large windows, and a city view.
A modern interior with a central seating area, potted plants, and a staircase.
A modern building with a sign reading 'HYATT REGENCY.'

10. Hyatt Regency Panama City

Hyatt Regency Panama City
Bella Vista
  • Indulgence awaits in this 4.5-star Panama City sanctuary featuring a full-service spa, outdoor pool, and elegant dining near Via Espana.
P11,777
P12,955 total
includes taxes & fees
Oct 31 - Nov 1
Hyatt Regency Panama City
View all properties

Top Colon Hotel Reviews

Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

8/10 Good
"Me encanta quedarme en este hotel es como mi segundo hogar hace años cada vez que visito Panama, es céntrico, mall es muy conveniente para mi."
CYNTHIA 1-night trip
Posted 6 hours ago
Courtyard by Marriott Panama Multiplaza Mall
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Food , staff very nice and helpful, clean room"
Rosa 3-night trip
Posted 8 hours ago
Hotel Riu Plaza Panama
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

10/10 Excellent
"Muy limpio y bonito, pero la limpieza tarda y se supone que cambian de toalla todos los días y un fia me dejaron la misma toalla húmeda."
Delia Janeth 3-night trip
Posted 10 hours ago
Las Americas Golden Tower Panama
Decapolis Hotel Panama City

Decapolis Hotel Panama City

10/10 Excellent
"Super"
Aleksandr 1-night trip
Posted 11 hours ago
Decapolis Hotel Panama City
Hotel Ojos del Rio

Hotel Ojos del Rio

10/10 Excellent
"Fueron vacaciones para mis padres, me comentaron que todo era excelente 👌"
Pedro Marcelo 3-night trip
Posted 12 hours ago
Hotel Ojos del Rio

Frequently asked questions

Are you looking for a luxury hotel for your Colon vacation?
Use Expedia to arrange your flight to Panama City (PAC-Marcos A. Gelabert Intl.) airport or Balboa (BLB-Panama Pacifico Intl.) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to find what you'd like to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Colon offers. Colon has some interesting things to see and do including Colon 2000 and Colon Free Zone, so you might want to take in the local sights during your visit.
What's the best high-end hotel in Colon?
Sand Diamond Hotel is a luxury hotel with ski-in/ski-out access and a casino, and it's a popular choice for Expedia travelers looking for an elegant place to stay.
When can I expect good weather in Colon?
Planning for the weather is an important factor for making your trip to Colon a success, especially when you're splurging. The hottest months are usually May and September with an average temp of 80°F, while the coldest months are January and February with an average of 79°F. The rainiest months in Colon are November, July, August, and October, with each month seeing an average of 14 inches of rainfall.
What's there to see and do in Colon?
Take in the sights and attractions that Colon offers with a visit to Colon 2000, Colon Free Zone, and Gamboa Rainforest Resort. If you have extra time while you're in the area, you might want to see Fantastic Casino | Colón 2000 and Fort San Lorenzo.
How can I get around Colon?
It's easier to get around town in style when you know your options. To see more of the larger area, ride aboard one of the trains from Colon Atlantic Passenger Station.