Colon Vacation Rentals

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Check prices for these dates

Tonight
Dec 28 - Dec 29
Tomorrow
Dec 29 - Dec 30
Next weekend
Jan 2 - Jan 4
In two weeks
Jan 9 - Jan 11

Our top choices for Colon vacation rentals

50-inch LED TV with satellite channels
Arcadia Condo Suites

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (175)
"Was a great buy. Beautiful views and spacious rooms. Great amenities. "
United States
Lesley
The price is P4,864
P8,065 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Arcadia Condo Suites
Lobby sitting area
San Francisco by Wynwood House

San Francisco by Wynwood House

San Francisco by Wynwood House
3.0 star property
San Francisco
9.2 out of 10, Wonderful, (56)
"Clean and walkable location"
United States
Tamera
The price is P7,006
P9,176 total
includes taxes & fees
Dec 29 - Dec 30
San Francisco by Wynwood House
Outdoor pool
Boutique Apartments Panama

Boutique Apartments Panama

Boutique Apartments Panama
3.5 star property
Bella Vista
7.6 out of 10, Good, (222)
"The view was amazing and the place was great could stay here again "
United States
Yonnette
Boutique Apartments Panama
Premium bedding, in-room safe, individually decorated
Las Clementinas

Las Clementinas

Las Clementinas
3.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (171)
"The front desk receptionist was extremely helpful! The room was clean and comfortable! We would definitely stay again!"
United States
april
The price is P8,898
P9,788 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Las Clementinas
Terrace/patio
La Isabela Suites

La Isabela Suites

La Isabela Suites
3.5 star property
Casco Viejo
10.0 out of 10, Exceptional, (171)
"Wonderful charming property in the heart of the historic district. "
United States
Angela
La Isabela Suites
Terrace/patio
Yoo Panamá by Boutique Apartments

Yoo Panamá by Boutique Apartments

Yoo Panamá by Boutique Apartments
3.5 star property
Bella Vista
8.2 out of 10, Very Good, (50)
"The hotel as well as the room exceeded our expectations. I would recommend staying at the Yoo via expedia. Thanks again... Reggie"
United States
Reginald
The price is P2,612
P11,039 total
includes taxes & fees
Dec 30 - Dec 31
Yoo Panamá by Boutique Apartments
Microwave, coffee/tea maker, cookware/dishes/utensils
La Palma Aparta Suite

La Palma Aparta Suite

La Palma Aparta Suite
3.0 star property
Amador
The price is P2,785
P4,825 total
includes taxes & fees
Dec 29 - Dec 30
La Palma Aparta Suite
Property grounds
Swette Love 10 Minutes From the Airport Tocumen

Swette Love 10 Minutes From the Airport Tocumen

Swette Love 10 Minutes From the Airport Tocumen
2.0 star property
Las Mañanitas
The price is P4,633
P5,788 total
includes taxes & fees
Jan 28 - Jan 29, 2026
Swette Love 10 Minutes From the Airport Tocumen
Outdoor pool
Boutique Apartments Atlapa

Boutique Apartments Atlapa

Boutique Apartments Atlapa
3.0 star property
San Francisco
8.0 out of 10, Very Good, (28)
"I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️"
United States
Shamia
Boutique Apartments Atlapa
Outdoor pool, free cabanas, sun loungers
Yoo Panama & Arts Tower

Yoo Panama & Arts Tower

Yoo Panama & Arts Tower
3.0 star property
Bella Vista
9.6 out of 10, Exceptional, (56)
"Ron was amazing and so was the property!"
United States
John
Yoo Panama & Arts Tower
Exterior
Centriqo by Wynwood house

Centriqo by Wynwood house

Centriqo by Wynwood house
3.0 star property
Veracruz
The price is P7,508
P10,197 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Centriqo by Wynwood house
Balcony
Casa Contemporanea by Wynwood House

Casa Contemporanea by Wynwood House

Casa Contemporanea by Wynwood House
4.0 star property
Casco Viejo
8.2 out of 10, Very Good, (20)
"Great place!"
United States
Jad
The price is P8,988
P11,356 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Casa Contemporanea by Wynwood House
Living area
Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (485)
"Room was clean, neat great staff"
United States
Alfredo
Torres de Alba Hotel & Suites
Outdoor pool
Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments
4.0 star property
San Francisco
10.0 out of 10, Exceptional, (1)
"I will go again thank you so much"
United States
GISY ITZEL
The price is P9,667
P19,617 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Wanders Panama by Boutique Apartments
Private beach
Habitación Privada en Playa Dorada + Kitchenette

Habitación Privada en Playa Dorada + Kitchenette

Habitación Privada en Playa Dorada + Kitchenette
3.0 star property
Vacamonte
The price is P1,410
P2,171 total
includes taxes & fees
Dec 29 - Dec 30
Habitación Privada en Playa Dorada + Kitchenette
Outdoor pool
Yoo by Wynwood House

Yoo by Wynwood House

Yoo by Wynwood House
4.0 star property
Calidonia
9.2 out of 10, Wonderful, (5)
"I will be back!"
United States
Jeffrey
The price is P7,878
P10,734 total
includes taxes & fees
Dec 29 - Dec 30
Yoo by Wynwood House
Living area
Casa Lefevre By Wynwood House

Casa Lefevre By Wynwood House

Casa Lefevre By Wynwood House
3.5 star property
Casco Viejo
8.8 out of 10, Excellent, (3)
"Once I remembered the email about access to the hotel it was all great from then on. A great surprise when I opened the door and saw this huge open space room. I loved it. "
United States
Jeff
The price is P9,292
P11,837 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Casa Lefevre By Wynwood House
Children's area
Charming 3 Bedroom Apartment in San Miguelito, Panama City

Charming 3 Bedroom Apartment in San Miguelito, Panama City

Charming 3 Bedroom Apartment in San Miguelito, Panama City
2.0 star property
José Domingo Espinar
The price is P4,232
P4,656 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Charming 3 Bedroom Apartment in San Miguelito, Panama City
2 bedrooms
Relaxing 2BR Apt at Coco del mar

Relaxing 2BR Apt at Coco del mar

Relaxing 2BR Apt at Coco del mar
2.0 star property
San Francisco
The price is P14,743
P16,217 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Relaxing 2BR Apt at Coco del mar
Living area
Edificio Doña Raquel

Edificio Doña Raquel

Edificio Doña Raquel
2.0 star property
Calidonia
Edificio Doña Raquel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Colon Hotel Reviews

JW Marriott Panama

JW Marriott Panama

10/10 Excellent
"All of it Fantastic "
Farhad 7-night trip
Posted 11 hours ago
JW Marriott Panama

Find out more about Colon

Search for holiday rentals in Colon on Expedia! You can easily find your home rentals, villas, holiday apartments in Colon using one of the methods below:

  • View our selection of featured holiday rentals in Colon
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  • Enter your travel dates to view the best deals on holiday rentals in Colon while they last

Look no further and take a look at our great range of rental properties in Colon!

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Frequently asked questions

Can I find a vacation rental in Colon?

Yes, we give you a choice of vacation rentals close to top local attractions in Colon, or you can go with a secluded option if you want a relaxing place to stay. Discover why Colon is known for its shops and lakeside.

How many vacation rentals are there in Colon?

With 3 Expedia vacation rentals, you're sure to find just the right place for your Colon stay.

What’s there to see and do in Colon?

Gamboa Rainforest Resort and Limon Bay are a couple of scenic spots to enjoy the outdoors, whereas Colón Art and Culture Center is one of the cultural attractions. Colon 2000 and Colon Free Zone are other places to visit while you're in town.

What’s a vacation rental in Colon like?

Vacation rentals are privately owned properties you can stay in for a couple of days or more in Colon. Vacation rentals feature extras like WiFi and washers and dryers so you'll have everything you want. If you're concerned about a sanitized environment, vacation rentals can offer a sense of privacy away from public hotel elevators and busy reception areas while still allowing you the enjoyment of travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive choice for a small group gathering.