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Hotels near Calle 50

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Our top choices for Calle 50 hotels

Hyatt Regency Panama City

Hyatt Regency Panama City
4.5 star property
Campo Alegre, 1.2 km from Calle 50
10.0 out of 10, Exceptional, (126)
"Great hotel fair price"
United States
Santiago
The price is P9,205
P10,125 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Hyatt Regency Panama City

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco, 1 km from Calle 50
9.6 out of 10, Exceptional, (1119)
"The hotel is in a great location in Panama. Great amenities excellent breakfast."
United States
Maria
The price is P5,750
P6,325 total
includes taxes & fees
Jan 10 - Jan 11, 2026
Ramada Plaza by Wyndham Panama Punta Pacifica

Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Campo Alegre, 1.1 km from Calle 50
9.4 out of 10, Exceptional, (1000)
"Great staff, super accommodating. Best place to stay in Panama!"
United States
Sebastian
The price is P11,780
P12,958 total
includes taxes & fees
Jan 14 - Jan 15, 2026
Bristol Panama, a Registry Collection Hotel

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
Punta Paitilla, 1.3 km from Calle 50
9.4 out of 10, Exceptional, (2136)
"Great location of the hotel with a lovely breakfast and friendly staff"
United States
fouad
The price is P6,339
P6,973 total
includes taxes & fees
Dec 25 - Dec 26
Plaza Paitilla Inn Hotel

The Executive Hotel

The Executive Hotel
3.5 star property
Campo Alegre, 1.2 km from Calle 50
9.2 out of 10, Wonderful, (1004)
"A nice hotel to stay great location"
United States
angela
The Executive Hotel

Novotel Panama City

Novotel Panama City
4.0 star property
El Cangrejo, 1.1 km from Calle 50
9.2 out of 10, Wonderful, (1031)
"Great service, big room, solid breakfasts.. all at good price."
Canada
Nicholas
The price is P6,236
P6,860 total
includes taxes & fees
Dec 23 - Dec 24
Novotel Panama City

Gran Evenia Panama

Gran Evenia Panama
4.5 star property
El Cangrejo, 1 km from Calle 50
9.2 out of 10, Wonderful, (195)
"The property was conveniently located near shops, restaurants and casinos. The food at breakfast was good. Although the pancakes could be better. "
United States
Nicole
Gran Evenia Panama

MARINN PLACE Financial District

MARINN PLACE Financial District
3.5 star property
Campo Alegre, 1.2 km from Calle 50
9.2 out of 10, Wonderful, (299)
"Second stay, very nice"
Canada
Xiaozhi
The price is P6,577
P7,235 total
includes taxes & fees
Dec 22 - Dec 23
MARINN PLACE Financial District

TRYP by Wyndham Panamá Centro

TRYP by Wyndham Panamá Centro
3.5 star property
El Cangrejo, 1.4 km from Calle 50
9.2 out of 10, Wonderful, (1001)
"Great staff and the room was very clean. "
United States
JOHNNY
The price is P5,740
P6,314 total
includes taxes & fees
Dec 22 - Dec 23
TRYP by Wyndham Panamá Centro

San Francisco by Wynwood House

San Francisco by Wynwood House
3.0 star property
San Francisco, 1.2 km from Calle 50
9.2 out of 10, Wonderful, (56)
"Clean and walkable location"
United States
Tamera
The price is P8,509
P10,828 total
includes taxes & fees
Dec 22 - Dec 23
San Francisco by Wynwood House

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 0.7 km from Calle 50
9.0 out of 10, Wonderful, (4697)
"Awesome great place to stay "
United States
Herbert
The price is P6,422
P7,064 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Hotel Riu Plaza Panama

Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
San Francisco, 0.4 km from Calle 50
9.0 out of 10, Wonderful, (1005)
"Staff was very helpful. Great location."
United States
John
The price is P5,441
P5,985 total
includes taxes & fees
Jan 10 - Jan 11, 2026
Courtyard by Marriott Panama Multiplaza Mall

Principe Hotel and Suites

Principe Hotel and Suites
3.0 star property
El Cangrejo, 0.9 km from Calle 50
9.0 out of 10, Wonderful, (1607)
"Friendly staff. "
United States
Thessely
The price is P2,995
P3,294 total
includes taxes & fees
Dec 24 - Dec 25
Principe Hotel and Suites

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
Punta Paitilla, 0.9 km from Calle 50
9.0 out of 10, Wonderful, (1003)
"I loved my stay! "
United States
Jenniffer Gonzalez De La
The price is P9,479
P10,427 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Las Americas Golden Tower Panama

Hotel Milan

Hotel Milan
3.0 star property
El Cangrejo, 1.3 km from Calle 50
9.0 out of 10, Wonderful, (429)
"It was a very pleasant experience the hotel is located in a great neighborhood, staff were friendly and competent, secure property and parking, clean and decent accommodations, especially at the room price point. "
Canada
Roger
The price is P2,349
P2,584 total
includes taxes & fees
Dec 22 - Dec 23
Hotel Milan

Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
4.0 star property
Punta Paitilla, 1 km from Calle 50
9.0 out of 10, Wonderful, (540)
"It's location is close to everything. "
United States
Sharon
The price is P9,434
P10,377 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Residence Inn by Marriott Panama City

Panama House Bed & Breakfast

Panama House Bed & Breakfast
2.5 star property
Bella Vista, 1 km from Calle 50
9.0 out of 10, Wonderful, (185)
"It was a great stay in a great neighborhood with many food and beverage options, fantastic hosts and an interesting mix of people "
Canada
Brad
The price is P2,426
P2,668 total
includes taxes & fees
Dec 22 - Dec 23
Panama House Bed & Breakfast

Hotel Coral Suites

Hotel Coral Suites
3.5 star property
El Cangrejo, 1.2 km from Calle 50
9.0 out of 10, Wonderful, (1001)
"The entire staff were amazing! Everyone exceeded my expectations including the front desk, cleaning team, bellhop and the restaurant next door was a plus. "
United States
Conchita
The price is P3,911
P4,302 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hotel Coral Suites

Best Western Plus Panama Zen Hotel

Best Western Plus Panama Zen Hotel
4.0 star property
El Cangrejo, 1.1 km from Calle 50
9.0 out of 10, Wonderful, (984)
"Great view Great buffet Breakfast was excellent "
Canada
Robert
The price is P5,333
P5,866 total
includes taxes & fees
Dec 22 - Dec 23
Best Western Plus Panama Zen Hotel

W Panama

W Panama
5.0 star property
Campo Alegre, 1.1 km from Calle 50
9.0 out of 10, Wonderful, (1005)
"Great vibes"
United States
Ashley
The price is P11,697
P12,867 total
includes taxes & fees
Jan 3 - Jan 4, 2026
W Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Calle 50 Hotel Reviews

Hotels near other Calle 50 attractions

Find out more about Calle 50

Top reasons to visit Calle 50

  • Vibrant Atmosphere: Calle 50 is alive with energy, featuring lively streets filled with modern architecture and bustling cafés.
  • Cultural Experiences: The area offers a rich cultural tapestry, perfect for immersing oneself in local traditions and events.
  • Scenic Bike Rides: Enjoy delightful bike rides along the thoroughfare, taking in the stunning sights at your own pace.
  • Accommodation Variety: From luxurious hotels to budget-friendly hostels, Calle 50 caters to all types of travellers.
  • Proximity to the Pacific: Just moments away from the ocean, enjoy breathtaking views and relaxation opportunities.

Find great hotels near Calle 50

Calle 50 in Panama City offers a diverse selection of accommodation options, from luxurious hotels to budget-friendly hostels. Ideal for both business travellers and families, the area features popular establishments such as W Panama, Panama Zen Hotel, and Megapolis Hotel Panama. Many hotels provide essential amenities, including free parking, ensuring a comfortable and convenient stay as you explore the vibrant surroundings of this bustling metropolis.

  • Hotel Riu Plaza Panama: Experience a blend of modern elegance and eco-conscious living at the Hotel Riu Plaza Panama, a 4-star establishment located 966m from Calle 50. Ideal for business travellers and eco-friendly guests, this city-themed hotel boasts a central location that makes it easy to explore Panama City. With its eco-certification, you can rest assured that your stay contributes to sustainable tourism. Guests appreciate the hotel’s contemporary design, spacious rooms, and a variety of on-site amenities, including restaurants and meeting facilities tailored for corporate needs.
  • Novotel Panama City: Perfect for families and business travellers alike, Novotel Panama City is situated 1.3km from Calle 50. This 4-star hotel offers a welcoming atmosphere with a focus on family-friendly amenities. Children can enjoy free cribs, a dedicated kids' club, and a shared playground, ensuring that younger guests feel right at home. The hotel features comfortable, modern rooms and a variety of dining options, making it a fantastic choice for both leisure and business trips in a vibrant urban setting.
  • Plaza Paitilla Inn Hotel: Embrace romance and relaxation at the Plaza Paitilla Inn Hotel, a charming 3.5-star venue located 1.4km from Calle 50. This hotel caters to couples seeking a romantic getaway, offering special romance packages and limited-hour room service for intimate dining experiences. Guests can unwind together with spa services that include Swedish massages and body treatments, as well as access to a pool for a refreshing dip. Its inviting atmosphere makes it a perfect choice for those looking to mix business with pleasure.

Where to stay near Calle 50

Calle 50 in Panama City offers an exciting blend of business and leisure, perfect for any traveller. Explore the vibrant business district, where modern skyscrapers meet charming cafés, and enjoy the warm hospitality of the locals. Just a stone's throw away lies the stunning Pacific Ocean, ideal for relaxation and scenic views. Discover Marbella, a trendy neighbourhood with a mix of luxury and budget options, making it an excellent base for exploring the rich history of South America.

  • Panama City: As the vibrant capital of Panama, Panama City is a bustling metropolis that offers a rich blend of cultural experiences and modern conveniences. Calle 50, a major thoroughfare, is located within this dynamic city. Visitors can enjoy a variety of activities, including shopping at numerous malls and centres, exploring local parks, or relaxing at nearby beaches. The city's visitor numbers remain consistently high, particularly in January, July, and September, making it a popular destination for family, business, and city-themed experiences. With its diverse attractions, Panama City is sure to offer an unforgettable travel experience.
  • Obarrio: Just 483m from Calle 50, Obarrio is a trendy neighbourhood known for its upscale vibe and vibrant commercial scene. The area attracts visitors year-round, with peak times in February, April, and September. Obarrio is ideal for those seeking family-friendly activities, business opportunities, or a lively city atmosphere. Shoppers will delight in the variety of shopping areas and centres available. The neighbourhood is also home to lovely parks and streets that invite leisurely strolls, making it a charming spot to explore during your stay.
  • Bella Vista: Encompassing Calle 50, Bella Vista is a lively neighbourhood that boasts a mix of residential and commercial spaces. This area sees a steady flow of tourists, particularly from February to March and in December. Visitors are drawn to Bella Vista for its family-oriented atmosphere, business facilities, and endless city-themed experiences. The neighbourhood features shopping centres and areas, along with parks and tourist precincts that provide ample leisure opportunities. Bella Vista is perfect for those looking to immerse themselves in the local culture while enjoying the conveniences of urban living.

Things to do near Calle 50

In Calle 50, Panama City, you can enjoy a delightful bike ride along the vibrant streets, taking in the stunning architecture and lively atmosphere. This area is known for its modern developments and offers a great opportunity to explore local cafés and shops at your own pace. Don't miss the chance to experience the city's dynamic culture while cycling through one of its busiest thoroughfares.

Shopping

In Calle 50, enjoy shopping at Multiplaza Pacific Mall, just 322m away, and Soho City Center, 644m away, both offering a vibrant mix of entertainment and family-friendly vibes. For a unique experience, Pacific Center is also nearby at 966m.

Recreation

Experience the energetic atmosphere at Estadio Rommel Fernandez, where you can enjoy various sports events. Alternatively, immerse yourself in the vibrant sports vibes at Estadio Nacional Rod Carew and Maracana Stadium, both offering engaging activities just a short distance from Calle 50.

Adventure

The Honeycreeper Ridge Trail offers a stunning hiking experience, located 38.6km from Calle 50. Experience the breathtaking scenery and immerse yourself in nature's beauty. For thrill-seekers, Gatun Eco Adventures features an exhilarating zipline ropes course, situated 46.7km away, perfect for an adrenaline-filled adventure amidst lush landscapes.

Nightlife

The nightlife in Calle 50 is vibrant, with cultural experiences awaiting at the National Theatre and Anita Villalaz Theatre, both offering romance and entertainment just 4.8km away. For a closer option, enjoy the Theatre Circle, located 1.6km from Calle 50, perfect for an engaging night out.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Calle 50

To save money during your visit to Calle 50, consider travelling between September and November when hotel prices are lower, particularly on Tuesdays. Avoid Saturdays for accommodation, as they tend to be pricier. Use Expedia's search tool to find budget-friendly options and filter for eco-certified hotels. Take advantage of package deals that combine flights, hotels, and activities for additional savings. For transport, utilise the affordable local bus services, and explore the area on foot to enjoy free attractions while immersing yourself in the vibrant surroundings.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Calle 50 are September to November, where the prices are slightly lower. This is in comparison to January and March to April, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Calle 50 is Tuesday. The most expensive day to stay around Calle 50 is Saturday.
  • Find cheap hotels on Expedia: Expedia’s search tool enables you to specify your budget and preferred location, among other options. You can arrange your search results to display prices from lowest to highest, ensuring you see the most affordable hotels first. Additionally, you have the option to refine your choices by hotel type; for instance, by selecting the Eco-certified filter, you’ll discover sustainable and environmentally-friendly hotels ready for booking.
  • Consider bundling your trip: You can enjoy savings by combining your Calle 50 hotel reservation with your flights and activities through an Expedia package.

Find the best attractions near Calle 50

Calle 50 in Panama City boasts a vibrant mix of attractions, including lively streets, urban parks, and event venues, catering to tourists seeking cultural experiences and family-friendly activities. This bustling area offers a variety of points of interest, perfect for immersing oneself in the local atmosphere and exploring the rich urban landscape.

  • ATLAPA Conventions Center: Located 1.4km from Calle 50, this venue is known for its vibrant business atmosphere, hosting a variety of conferences and exhibitions. The architectural design is striking, making it a hub for professionals from around the world.
  • Megapolis Convention Center: Situated 1.3km away, this modern conference venue is another key player in Panama City’s business scene. It features state-of-the-art facilities and often hosts industry events, attracting attendees with its sleek design.
  • Cinta Costera: About 3.2km from Calle 50, this beautiful urban park offers a refreshing outdoor experience. Ideal for families, it features scenic pathways, recreational areas, and stunning views of the city skyline, perfect for relaxation or a leisurely stroll.

Best time to go to Calle 50

The best time to visit Calle 50 can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around Calle 50 falls in April, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature around Calle 50 falls in November, visitor numbers are average and weather is mostly cloudy with frequent rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January78.8°F (26.0°C)No RainMostly SunnyAverageSlightly High
February79.2°F (26.2°C)No RainMostly SunnySlightly HighAverage
March79.7°F (26.5°C)No RainMostly SunnySlightly HighSlightly High
April80.4°F (26.9°C)Light RainMostly SunnyAverageSlightly High
May80.2°F (26.8°C)Frequent RainMostly CloudySlightly LowAverage
June79.9°F (26.6°C)Frequent RainMostly CloudySlightly LowAverage
July79.3°F (26.3°C)Frequent RainMostly CloudyAverageAverage
August79.2°F (26.2°C)Frequent RainMostly CloudyAverageAverage
September79.3°F (26.3°C)Frequent RainMostly CloudySlightly LowSlightly Low
October78.6°F (25.9°C)Frequent RainMostly CloudyAverageSlightly Low
November78.3°F (25.7°C)Frequent RainMostly CloudyAverageSlightly Low
December78.6°F (25.9°C)Light RainMostly CloudySlightly HighAverage

The nearest major airports for your trip to Calle 50

Accessing Calle 50 in Panama City is convenient with three major airports nearby. Panama City’s Marcos A. Gelabert International Airport (PAC) is situated 4.8km away, with notable hotels like the 5-star W Panama, just 3.2km from the airport. Balboa's Panama Pacifico International Airport (BLB) is 11.3km from Calle 50, offering excellent accommodation options such as the elegant Sofitel Legend Casco Viejo, 8.0km away. Finally, Tocumen International Airport (PTY) lies 16.1km from Calle 50, with luxurious stays like The Santa Maria, 8.0km distant. Each hotel provides various transport services to their respective airports, ensuring a seamless travel experience.

Frequently asked questions

What's the area like around Calle 50?
Calle 50 is located in Panama City. This welcoming area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, check out the 471 hotels and other accommodations you'll find within a mile.
What's the best place to stay near Calle 50?
Adjacent to Calle 50, Courtyard by Marriott Panama Multiplaza Mall is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good options close by include Hotel Riu Plaza Panama and Las Americas Golden Tower Panama.
How many hotels will I be able to find near Calle 50?
Expedia has 471 hotels and other accommodations within a mile from Calle 50.
If I need to cancel the hotel reservation for my stay near Calle 50, will I receive a refund?
Yes! Most hotel bookings are fully refundable provided that you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of your booking. Add dates, click "Search", then use the "fully refundable" filter to view the best deals available near Calle 50.
What can I see and do near Calle 50?
You'll want to browse the collections at Interoceanic Canal Museum, Biomuseo, and Colonial Religious Art Museum. Iglesia del Carmen, Panama Viejo, and Panama Canal Railway are notable landmarks to explore if you're in the area. You can catch a show at National Theater, Theater Circle, and Anita Villalaz Theater.
How can I get to Calle 50?
Local metro stations include Iglesia del Carmen Station and Vía Argentina. If you'd like to explore around the surrounding area, you may want a car rental for your journey.

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