Hotels near Buffalo Museum of Science

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Dec 28 - Dec 29
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Our top choices for Buffalo Museum of Science hotels

Interior
InnBuffalo off Elmwood

InnBuffalo off Elmwood

InnBuffalo off Elmwood
2.5 star property
Elmwood Village, 3 km from Buffalo Museum of Science
10.0 out of 10, Exceptional, (190)
"Our favorite inn!! Beautifully and lovingly restored — wonderful staff, rooms, fresh breakfasts…a gem, to be sure."
United States
katherine
The price is P6,932
P7,954 total
includes taxes & fees
Jan 7 - Jan 8, 2026
InnBuffalo off Elmwood
Staircase
The Edward Hotel

The Edward Hotel

The Edward Hotel
3.0 star property
Elmwood Village, 2.4 km from Buffalo Museum of Science
9.6 out of 10, Exceptional, (219)
"Great location in Elmwood Village area. Clean room with gas fireplace. Self check- in was easy with staff provided instructions. Many food options within walking distance. "
United States
Jon
The Edward Hotel
Exterior
The Mansion On Delaware Ave

The Mansion On Delaware Ave

The Mansion On Delaware Ave
4.0 star property
Allentown, 3 km from Buffalo Museum of Science
9.4 out of 10, Exceptional, (1002)
"Fantastic place!"
Canada
Geneviève
The Mansion On Delaware Ave
Lobby
Wyndham Garden Buffalo Downtown

Wyndham Garden Buffalo Downtown

Wyndham Garden Buffalo Downtown
3.0 star property
Downtown Buffalo, 2 km from Buffalo Museum of Science
9.0 out of 10, Wonderful, (1720)
"Great hotel!"
United States
Donovan
The price is P7,265
P8,482 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Wyndham Garden Buffalo Downtown
Exterior
Buffalo Guesthouse

Buffalo Guesthouse

Buffalo Guesthouse
3.0 star property
Allentown, 2.4 km from Buffalo Museum of Science
9.0 out of 10, Wonderful, (119)
"Fantastic stay at the Buffalo Guesthouse. It has a real home feeling. Lovely staff( real friendly atmosphere where you actually engage with other people staying there. Clean, well located and secure. "
Australia
Benjamin
The price is P5,774
P6,625 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Buffalo Guesthouse
Restaurant
Residence Inn by Marriott Buffalo Downtown

Residence Inn by Marriott Buffalo Downtown

Residence Inn by Marriott Buffalo Downtown
3.0 star property
Allentown, 2.6 km from Buffalo Museum of Science
9.0 out of 10, Wonderful, (336)
"Very comfortable, pleasant staff, great breakfast Clean, convenient, easy safe parking . Exceptional "
United States
Raymond
The price is P12,866
P15,021 total
includes taxes & fees
Dec 29 - Dec 30
Residence Inn by Marriott Buffalo Downtown
Desk, laptop workspace, blackout drapes, iron/ironing board
Best Western on the Avenue

Best Western on the Avenue

Best Western on the Avenue
2.5 star property
Allentown, 2.8 km from Buffalo Museum of Science
8.6 out of 10, Excellent, (1000)
"The rooms were great. The staff was friendly and professional. Breakfast was awesome. Allentown location was ideal. I would stay here for my next visit."
United States
DAVID
The price is P7,879
P9,198 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Best Western on the Avenue
In-room safe, blackout drapes, free cribs/infant beds, free WiFi
Aloft Buffalo Downtown

Aloft Buffalo Downtown

Aloft Buffalo Downtown
3.0 star property
Buffalo Theater District, 3 km from Buffalo Museum of Science
8.2 out of 10, Very Good, (347)
"Clean room. Easy access to parking garage. "
United States
Clay
The price is P12,454
P14,540 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Aloft Buffalo Downtown
Reception
Buffalo Harmony House

Buffalo Harmony House

Buffalo Harmony House
4.5 star property
Allentown, 3.2 km from Buffalo Museum of Science
10.0 out of 10, Exceptional, (47)
"Amazing breakfasts!"
United States
David
Buffalo Harmony House
Private kitchen
Summer Street Guest House

Summer Street Guest House

Summer Street Guest House
3.0 star property
Bryant, 3 km from Buffalo Museum of Science
10.0 out of 10, Exceptional, (2)
"Beautiful old mansion lovingly restored with so much charm! This was a fantastic location for our needs. We were able to walk past estates and cute cottages with beautiful gardens to shops and restaurants for breakfast and lunch. Close to the Buffalo History Museum and other local attractions and about 20 minutes from Niagara Falls. Our host was able to let us have an early check in time and he gave us a tour of the house with some interesting background info. He lives quietly on the third...
United States
Anonymous traveler
The price is P21,096
P30,949 total
includes taxes & fees
Dec 29 - Dec 30
Summer Street Guest House
Exterior
Buffalo Marriott at LECOM HARBORCENTER

Buffalo Marriott at LECOM HARBORCENTER

Buffalo Marriott at LECOM HARBORCENTER
3.5 star property
Downtown Buffalo, 4.4 km from Buffalo Museum of Science
9.4 out of 10, Exceptional, (891)
"Our stay was amazing! The staff at the front desk was very helpful. "
United States
Bobbi Jo
The price is P14,628
P17,078 total
includes taxes & fees
Dec 29 - Dec 30
Buffalo Marriott at LECOM HARBORCENTER
American cuisine
Reikart House, Buffalo, a Tribute Portfolio Hotel

Reikart House, Buffalo, a Tribute Portfolio Hotel

Reikart House, Buffalo, a Tribute Portfolio Hotel
4.0 star property
8.3 km from Buffalo Museum of Science
9.6 out of 10, Exceptional, (683)
"Very nice hotel, well maintained, clean and high class. "
United States
Brian
The price is P15,274
P17,374 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Reikart House, Buffalo, a Tribute Portfolio Hotel
Hallway
The Richardson Hotel

The Richardson Hotel

The Richardson Hotel
3.5 star property
Elmwood Bidwell, 4.1 km from Buffalo Museum of Science
9.0 out of 10, Wonderful, (1005)
"Rhe property is amazing and the staff are too. Jessica made our stay special"
United States
Cindy
The price is P7,400
P8,639 total
includes taxes & fees
Jan 6 - Jan 7, 2026
The Richardson Hotel
Exterior
Courtyard Buffalo Downtown / Canalside

Courtyard Buffalo Downtown / Canalside

Courtyard Buffalo Downtown / Canalside
3.0 star property
Downtown Buffalo, 4.3 km from Buffalo Museum of Science
9.0 out of 10, Wonderful, (960)
"Very clean room, nice pool with lots of towels, good breakfast selection. "
United States
Jessica
The price is P10,187
P11,893 total
includes taxes & fees
Jan 26 - Jan 27, 2026
Courtyard Buffalo Downtown / Canalside
Couples treatment rooms, body treatments, hot stone massages
The Mosey Buffalo Williamsville, Tapestry Collection by Hilton

The Mosey Buffalo Williamsville, Tapestry Collection by Hilton

The Mosey Buffalo Williamsville, Tapestry Collection by Hilton
4.0 star property
9 km from Buffalo Museum of Science
9.4 out of 10, Exceptional, (1001)
"Very clean and modern rooms. Great bar in the hotel. Overall great stay. "
United States
Rich
The price is P8,382
P9,535 total
includes taxes & fees
Jan 8 - Jan 9, 2026
The Mosey Buffalo Williamsville, Tapestry Collection by Hilton
Exterior
Hampton Inn & Suites Buffalo Downtown

Hampton Inn & Suites Buffalo Downtown

Hampton Inn & Suites Buffalo Downtown
2.5 star property
Buffalo Theater District, 3.4 km from Buffalo Museum of Science
8.8 out of 10, Excellent, (1002)
"Great location "
United States
Oscar
The price is P7,852
P9,167 total
includes taxes & fees
Jan 21 - Jan 22, 2026
Hampton Inn & Suites Buffalo Downtown
Terrace/patio
Home2 Suites by Hilton Buffalo Airport / Galleria Mall

Home2 Suites by Hilton Buffalo Airport / Galleria Mall

Home2 Suites by Hilton Buffalo Airport / Galleria Mall
3.0 star property
6.3 km from Buffalo Museum of Science
9.0 out of 10, Wonderful, (1001)
"Good size rooms, and comfortable beds too! Good location with restaurants and shopping close by! Would recommend this hotel. "
Canada
Ann
The price is P7,708
P8,767 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Home2 Suites by Hilton Buffalo Airport / Galleria Mall
Exterior
Hampton Inn Buffalo - Amherst, NY

Hampton Inn Buffalo - Amherst, NY

Hampton Inn Buffalo - Amherst, NY
2.5 star property
10.6 km from Buffalo Museum of Science
9.4 out of 10, Exceptional, (1996)
"Great room, staff, breakfast, and pool- would definitely stay here again!"
United States
Madison
The price is P6,214
P7,069 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Hampton Inn Buffalo - Amherst, NY
Exterior detail
Hilton Garden Inn Buffalo Downtown

Hilton Garden Inn Buffalo Downtown

Hilton Garden Inn Buffalo Downtown
3.0 star property
Buffalo Theater District, 3.5 km from Buffalo Museum of Science
8.6 out of 10, Excellent, (1002)
"Everything was amazing even the front desk very helpful and very knowledgeable about the area. Thanks for the hospitality "
United States
Omar
The price is P5,609
P6,549 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Hilton Garden Inn Buffalo Downtown
Lobby
Hotel at the Lafayette Trademark Collection by Wyndham

Hotel at the Lafayette Trademark Collection by Wyndham

Hotel at the Lafayette Trademark Collection by Wyndham
3.5 star property
Buffalo Theater District, 3.6 km from Buffalo Museum of Science
8.6 out of 10, Excellent, (1003)
"I love the history in the hotel "
United States
Dylan
The price is P6,342
P7,404 total
includes taxes & fees
Jan 26 - Jan 27, 2026
Hotel at the Lafayette Trademark Collection by Wyndham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Buffalo Museum of Science Hotel Reviews

Wyndham Garden Buffalo Downtown

Wyndham Garden Buffalo Downtown

10/10 Excellent
"Best breakfast around. Better than the slop I had at Cracker Barrel. Your staff is sooooo amazingly friendly and helpful. That is why I stay here. "
Ruth 1-night trip
Posted 20 hours ago
Wyndham Garden Buffalo Downtown

Hotels near other Buffalo Museum of Science attractions

Buffalo Central Terminal

You can find out about the history of Buffalo when you stop by Buffalo Central Terminal. Experience the great live music and entertainment choices in this vibrant area.
See properties

War Memorial Stadium

Explore the great outdoors at War Memorial Stadium, a lovely green space in Buffalo. Experience the area's entertainment choices and acclaimed theater scene.
See properties

Frequently asked questions

What's the area like around Buffalo Museum of Science?
Buffalo Museum of Science is located in a historic area of Buffalo known for its great live music scene. If you're looking for a convenient place to stay, check out the 10 hotels and other accommodations you'll find within a mile.
What's the best hotel to stay near Buffalo Museum of Science?
Hyatt Regency Buffalo / Hotel and Conference Center is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an indoor pool. It's located 2.1 mi (3.4 km) from Buffalo Museum of Science. Other good choices within 5 miles include Wyndham Garden Buffalo Downtown and Buffalo Guesthouse.
How many hotels will I be able to find close to Buffalo Museum of Science?
Expedia has 10 hotels and other accommodations within a mile from Buffalo Museum of Science.
If I need to cancel the hotel reservation for my stay near Buffalo Museum of Science, will I receive a refund?
Yes, most hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the top deals on offer near Buffalo Museum of Science.
What can I see and do near Buffalo Museum of Science?
Study the collections at Buffalo AKG Art Museum, Buffalo History Museum, or Buffalo and Erie County Naval and Military Park. Some landmarks that you won't want to miss include Buffalo Central Terminal, Statler Tower, and Peace Bridge. You can watch performances at Shea's Performing Arts Center, Kleinhans Music Hall, and Road Less Traveled Theater if you're interested in local theater.