A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

Panama City 5 Stars Hotels

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Check availability on Panama City 5 Star Hotels

Tonight
Oct 26 - Oct 27
Tomorrow
Oct 27 - Oct 28
This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

Our top choices for Panama City 5-star hotels

A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.
A spacious lobby with a central seating area, a chandelier, and a modern ceiling design.
A modern living room with a sofa set, a coffee table, and a dining area with chairs and a table.
A modern hotel room with a dining area, a TV, and a city view.

1. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
Bella Vista
Canada
Sean
P7,610
P8,371 total
includes taxes & fees
Nov 22 - Nov 23
Hotel Riu Plaza Panama
A modern building with a rooftop lounge area, large windows, and a balcony overlooking a cityscape.
A modern interior with a decorative ceiling, a person in a white dress, and a blue-lit wall.
A tall, modern building with a prominent logo at the top, surrounded by other high-rise buildings in a cityscape.
An outdoor seating area with wicker chairs and tables, large windows offering a city view at dusk.

2. Waldorf Astoria Panama

Waldorf Astoria Panama
Bella Vista
United States
Aysha
P17,245
P18,969 total
includes taxes & fees
Nov 14 - Nov 15
Waldorf Astoria Panama
A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.
A modern interior with a central seating area, potted plants, and a staircase.
A spacious lobby with a curved ceiling, a central staircase, and a reception desk.
A modern building with a sign reading 'HYATT REGENCY.'

3. Hyatt Regency Panama City

Hyatt Regency Panama City
Bella Vista
United States
Mariah
P11,893
P13,082 total
includes taxes & fees
Nov 1 - Nov 2
Hyatt Regency Panama City
A poolside area with lounge chairs and a view of the ocean.
A modern hotel room with a large bed, a chair, a nightstand with a lamp, and a view of the cityscape at dusk.
A terrace with seating and a view of the ocean.
A modern bathroom with a large bathtub, two sinks, and a glass-enclosed shower area with a city view.

4. JW Marriott Panama

JW Marriott Panama
San Francisco
United States
GIORIA
P18,774
P20,652 total
includes taxes & fees
Nov 21 - Nov 22
JW Marriott Panama
A balcony with a table, chairs, and a view of a city skyline across a body of water.
A spacious lobby with high ceilings, modern furniture, and decorative lighting fixtures.
A spacious lobby with a round coffee table, seating areas, and a large wall clock.
A spacious living room with a high ceiling, large windows, and a decorative ceiling fan.

5. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
United States
Jose
P26,902
P29,593 total
includes taxes & fees
Nov 1 - Nov 2
Sofitel Legend Casco Viejo, Panama City
A hotel entrance with a central water feature, seating areas, and potted plants.
A hotel entrance with a sign reading 'THE SANTA MARIA' and a covered entrance area with columns and potted plants.
A lobby with a central table, potted plants, and a modern ceiling design.
An outdoor dining area with wicker chairs and tables, a bar with bottles, and a pool in the background.

6. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
United States
Carmen
P19,864
P21,850 total
includes taxes & fees
Nov 8 - Nov 9
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
A high-rise building with a rooftop pool area, surrounded by other buildings.
A modern hotel room with a large bed, a desk, a chair, and a view of the cityscape.
A modern living room with a city view, featuring a purple accent wall, a white sofa, and a glass table.
A modern high-rise building with a prominent 'W' logo, surrounded by other buildings and a busy street at night.

7. W Panama

W Panama
Bella Vista
United States
Naomi
P15,623
P17,185 total
includes taxes & fees
Nov 1 - Nov 2
W Panama
A modern hotel room with a sofa, a coffee table, a TV mounted on the wall, and a dining area with a table and chairs.
The exterior of the Renaissance Hotel with a modern design, featuring a prominent 'R' logo, a geometric ceiling design, and a well-lit entrance area.
An indoor swimming pool with lounge chairs and red chairs, surrounded by lush greenery and a modern interior design.
A modern lobby with a staircase, marble flooring, and large windows with tropical plants.

8. Renaissance Panama City Hotel

Renaissance Panama City Hotel
Bella Vista
United States
Carlos
P8,077
P8,885 total
includes taxes & fees
Nov 15 - Nov 16
Renaissance Panama City Hotel
A hotel courtyard with a central lawn, surrounded by buildings with balconies and outdoor seating areas.
A modern living room with a sofa, a coffee table, and a TV mounted on the wall.
A rooftop terrace with tables and chairs, a view of two white towers, and a building with a large window.
A restaurant with multiple dining tables, chairs, and a central water feature.

9. Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
Casco Viejo
United States
Carlos A
P19,029
P20,932 total
includes taxes & fees
Nov 1 - Nov 2
Hotel La Compañía Casco Antiguo
A modern living room with a sofa, round black ottomans, and a vase of flowers. A cityscape is visible through the window.
A person performing a yoga pose in a living room with a large window and a sofa.
A bar area with a long counter, multiple bar stools, and a television screen. There are large windows providing natural light and a view of the outdoors.
A cozy outdoor seating area with a wooden bench and white tables, surrounded by lush greenery and potted plants.

10. Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
Bella Vista
United States
Juliet
P13,461
P14,807 total
includes taxes & fees
Nov 13 - Nov 14
Bristol Panama, a Registry Collection Hotel
A modern hotel pool area with lounge chairs and a clear view of the ocean.
A spacious lobby with a large seating area, a glass display case with bottles, and a view of the city at night.
A modern interior with a spiral staircase, a large window, and a seating area.
A modern bar area with seating and a view of the city.

11. Hilton Panama

Hilton Panama
Bella Vista
United States
Simon
P16,704
P18,375 total
includes taxes & fees
Nov 20 - Nov 21
Hilton Panama
A hotel with a pool, beach, and palm trees.
A large hotel with multiple towers, a central courtyard with a swimming pool, and surrounding landscaped areas.
A beachfront hotel with a large building, a beach, and a clear sky.
A spacious lobby with a modern design, featuring a central seating area with sofas and ottomans, surrounded by large, open spaces and natural light.

12. The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
Veracruz
United States
Lyman
P13,108
P14,419 total
includes taxes & fees
Nov 10 - Nov 11
The Westin Playa Bonita Panama
Lobby
Breakfast area
Outdoor pool
A hotel room with two beds, a desk with a lamp, a chair, and a large window.

13. Waymore Hotel Spa and Casino

Waymore Hotel Spa and Casino
Bella Vista
United States
Mathe
Waymore Hotel Spa and Casino
Outdoor pool
Room
Terrace/patio
A modern hotel room with a sofa, armchair, and a television.

14. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
United States
MARVIN
P16,693
P18,438 total
includes taxes & fees
Nov 18 - Nov 19
Megapolis Hotel Panamá
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama City.
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Via Espana 111 Panama City Panama
P8,071
P8,878 total
Nov 23 - Nov 24
includes taxes & fees
7.8/10 Good! (1,008 reviews)
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama
P8,586
P9,864 total
Nov 3 - Nov 4
includes taxes & fees
8.6/10 Excellent! (2,788 reviews)
Crowne Plaza Panama Airport by IHG
Megapolis Hotel Panamá

Megapolis Hotel Panamá

Avenida Balboa Panama City
P10,160
P11,176 total
Oct 31 - Nov 1
includes taxes & fees
8.6/10 Excellent! (1,829 reviews)
Megapolis Hotel Panamá
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Panama City

The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch.

See all hotels in Panama City
A city skyline with high-rise buildings, a calm waterfront, and a sunset sky.

Top Panama City Hotel Reviews

Hyatt Regency Panama City

Hyatt Regency Panama City

10/10 Excellent
"Nice hotel. The restaurants have good food. We paid to have access to the club room, it was convenient and it offered a variety of food and drinks. I would recommend letting the front desk know if you plan to leave the hotel for the day to ensure your room gets cleaned."
Greg 10-night trip
Posted 2 hours ago
Hyatt Regency Panama City
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

8/10 Good
"Lindo lugar me volvería a hospedar"
nestor 2-night trip
Posted 8 hours ago
Hotel Riu Plaza Panama

Find out more about Panama City

Stay in Luxury: 5 Star Hotels in Panama City

There's nothing wrong with enjoying the finer things in life. Indulge your every desire on your upcoming leisure time. Treat yourself with a stay in a 5-star hotel during your Panama City trip. You'll join the multitudes of holidaymakers who have made Panama City so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Reserve one of our 5-star hotels in Panama City and indulge in the finer things in life for a while.

5-Star Hotels in Panama City

You'll have a wonderful time at one of these 5-star hotels. Exceptional customer care, luxurious bedding, and deeply relaxing spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What kind of amenities will make your stay a wonderful one? 24-hour room service, so you can order that berry tart in the wee hours of the morning? A body scrub that will leave you feeling refreshed and alive? Butler services? Whatever it is your heart desires, you're bound to find it here. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs. 

But you aren't going to spend your entire holiday in your room, of course. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Panama City are waiting for you to relax after an exciting day.

Make Your Escape

The results are in, and Panama City 5-star hotels are the place to be when you book your next holiday. If you've been dreaming about a holiday set here, then go ahead and book it. It's time to plan your next great escape -- this is a great time to find 5-star hotel deals in Panama City! Choose one of our Panama City 5-star hotels today and soothe yourself in luxe surroundings at your convenience.

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Frequently asked questions

What are the best 5-star hotels in Panama City?
Bristol Panama, a Registry Collection Hotel, W Panama and Waldorf Astoria Panama are some of the top 5-star hotels in Panama City, based on our guest reviews. These deluxe hotels rate highly for things such as their location, amenities and service standards. Pick your favorite and enjoy the best of it all.
How much does it cost to stay in a 5-star hotel in Panama City?
The amount you pay for a 5-star hotel in Panama City can vary according to when you prefer to travel and how long you plan to be away, among a range of factors. Use our price per night filter and other search tools to find the best rate on a plush stay.
  • Search for the lowest price per night from P8,878
What makes a hotel 5 stars in Panama City?
In Panama City, a hotel needs to offer a certain level of high-end conveniences to earn 5 stars. These can include gourmet restaurants, on-site gyms, saunas and spas, luxury toiletries, premium bedding and more. What also sets 5-star hotels apart is their exceptional standard of service. You can look forward to things like concierge services, in-room massages and nightly turn-down services. Some may even offer extra touches like a welcome gift.

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