A bench, a bicycle, and a lake surrounded by trees.

Upstate South Carolina 4 Stars Hotels

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Our top choices for Upstate South Carolina 4-star hotels

1. Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection
4.0 star property
Greenville Downtown
9.6 out of 10, Exceptional, (570 reviews)
"Wonderful"
United States
colleen
The price is P22,266
P25,227 total
includes taxes & fees
Nov 29 - Nov 30
Grand Bohemian Lodge Greenville, Autograph Collection

2. Hotel Hartness

Hotel Hartness
4.0 star property
Greenville
9.8 out of 10, Exceptional, (881 reviews)
"Beautiful property and very friendly staff! Highly recommend!"
United States
Nicole
The price is P10,456
P13,946 total
includes taxes & fees
Nov 22 - Nov 23
Hotel Hartness

3. The Westin Poinsett Greenville

The Westin Poinsett Greenville
4.0 star property
Greenville Downtown
9.4 out of 10, Exceptional, (1,001 reviews)
"This was our first stay and we were very impressed. Great location and helpful staff. Very nice room and comfy beds. Good restaurants within walking distance. Highly recommend."
United States
Mary C
The price is P10,115
P11,651 total
includes taxes & fees
Nov 22 - Nov 23
The Westin Poinsett Greenville

4. Mint House Greenville Downtown by Kasa

Mint House Greenville Downtown by Kasa
4.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (935 reviews)
"Great location, convenient!"
United States
Michelle
The price is P6,012
P6,613 total
includes taxes & fees
Dec 1 - Dec 2
Mint House Greenville Downtown by Kasa

5. The Abernathy of Clemson

The Abernathy of Clemson
4.0 star property
Clemson
9.6 out of 10, Exceptional, (657 reviews)
"Great place."
United States
John
The price is P9,676
P10,740 total
includes taxes & fees
Nov 15 - Nov 16
The Abernathy of Clemson

6. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
4.0 star property
Clemson
9.8 out of 10, Exceptional, (906 reviews)
"Always a wonderful stay!"
United States
Laurrie
The price is P13,296
P14,758 total
includes taxes & fees
Nov 4 - Nov 5
The Shepherd Hotel Downtown Clemson

7. Greenville Marriott

Greenville Marriott
4.0 star property
Greenville
8.6 out of 10, Excellent, (714 reviews)
"We had a great stay! Rooms were very clean and beds very comfortable!!"
United States
John
The price is P7,252
P8,217 total
includes taxes & fees
Nov 29 - Nov 30
Greenville Marriott

8. Doubletree By Hilton Greenville Airport

Doubletree By Hilton Greenville Airport
4.0 star property
Greer
9.4 out of 10, Exceptional, (33 reviews)
"Great stay"
United States
Brittany
The price is P7,773
P8,806 total
includes taxes & fees
Nov 19 - Nov 20
Doubletree By Hilton Greenville Airport

9. The Station by Compo Hotels

The Station by Compo Hotels
4.0 star property
Travelers Rest
10.0 out of 10, Exceptional, (24 reviews)
"great place perfect for more privacy vs. a standard hotel"
United States
John
The price is P13,939
P20,581 total
includes taxes & fees
Nov 29 - Nov 30
The Station by Compo Hotels

10. Hotel Domestique

Hotel Domestique
4.0 star property
Travelers Rest
9.8 out of 10, Exceptional, (37 reviews)
"Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away."
United States
Chuck
The price is P26,707
P29,378 total
includes taxes & fees
Nov 15 - Nov 16
Hotel Domestique

11. Landing Apartments Greer - Sugar Creek

Landing Apartments Greer - Sugar Creek
4.0 star property
Greer
9.2 out of 10, Wonderful, (5 reviews)
"The apartment was clean. Excellent value for stay. Amenities were great. Will book again!"
United States
Amanda
Landing Apartments Greer - Sugar Creek

12. Landing Furnished Apartments - Spartanburg, SC

Landing Furnished Apartments - Spartanburg, SC
4.0 star property
Spartanburg
Landing Furnished Apartments - Spartanburg, SC

13. Designer Retreat w/ Pool, Golf + Beach Access!

Designer Retreat w/ Pool, Golf + Beach Access!
4.0 star property
Salem
10.0 out of 10, Exceptional, (1 review)
"Property is in a great community, and it was very clean and beautifully decorated."
United States
Anonymous traveler
Designer Retreat w/ Pool, Golf + Beach Access!

14. Wooded Keowee Key Retreat Near Golf & Trails

Wooded Keowee Key Retreat Near Golf & Trails
4.0 star property
Salem
Wooded Keowee Key Retreat Near Golf & Trails

15. Lake Keowee Condo: Resort Pools & Lake Access!

Lake Keowee Condo: Resort Pools & Lake Access!
4.0 star property
Salem
10.0 out of 10, Exceptional, (2 reviews)
"Wow!! Absolutely beautiful property. Recent remodel with beautiful and very tasteful design. Amazingly clean, organized and tidy. We are from Denver and did not have exposure to Lake Keowee. The lake was beautiful with great walking trails on the property. Special and spectacular spot! We will definitely go back. This is a gated community. Super comfortable king beds and nice linens."
United States
Shawn
Lake Keowee Condo: Resort Pools & Lake Access!

16. Keowee Key Condo w/ Lake Access & Community Pools!

Keowee Key Condo w/ Lake Access & Community Pools!
4.0 star property
Salem
Keowee Key Condo w/ Lake Access & Community Pools!

17. Salem Vacation Rental w/ Lake Keowee Access!

Salem Vacation Rental w/ Lake Keowee Access!
4.0 star property
Salem
Salem Vacation Rental w/ Lake Keowee Access!

18. Views, Pools & Marina: Lake Keowee Condo!

Views, Pools & Marina: Lake Keowee Condo!
4.0 star property
Salem
Views, Pools & Marina: Lake Keowee Condo!

19. Tee Times & Lake Days! Luxe Keowee Key Living

Tee Times & Lake Days! Luxe Keowee Key Living
4.0 star property
Salem
Tee Times & Lake Days! Luxe Keowee Key Living

20. Lake Keowee Condo w/ Balcony & Resort Amenities!

Lake Keowee Condo w/ Balcony & Resort Amenities!
4.0 star property
Salem
10.0 out of 10, Exceptional, (1 review)
"This is a beautiful property in a beautiful location. Amenities are excellent. Beds are comfortable and there are plenty of towels and extra blankets. Kitchen is well stocked either basics for cooking. It took us about 25 minutes to get to Clemson- where we were visiting- but it is well worth the drive!"
United States
Kathleen
Lake Keowee Condo w/ Balcony & Resort Amenities!
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Learn more about Upstate South Carolina

Venture to sights like Discovery Island Water Park and Heritage Park as you discover Upstate South Carolina.

A multi-tiered waterfall cascading over rocks in a forested area.
Photo by Ryan Watts
Open Photo by Ryan Watts

Top Upstate South Carolina Hotel Reviews

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