Photo by Ryan Watts

Upstate South Carolina Hotels

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Upstate South Carolina hotels

Inn on the Square, an Ascend Collection Hotel

Inn on the Square, an Ascend Collection Hotel
3.0 star property
Uptown Greenwood
9.2 out of 10, Wonderful, (710)
"It was a very clean and beautiful lace to stay. We were there for our honeymoon "
United States
Tracy
The price is P6,131
P6,805 total
includes taxes & fees
Jan 25 - Jan 26
Inn on the Square, an Ascend Collection Hotel

Hampton Inn Easley

Hampton Inn Easley
2.5 star property
Easley
9.2 out of 10, Wonderful, (687)
"Clean room and convenient location."
United States
Gable
The price is P8,157
P9,054 total
includes taxes & fees
Jan 31 - Feb 1
Hampton Inn Easley

Four Points by Sheraton Spartanburg

Four Points by Sheraton Spartanburg
3.0 star property
Spartanburg
9.4 out of 10, Exceptional, (442)
"Friendly staff, clean rooms, excellent food! "
United States
Ashley
The price is P7,299
P8,102 total
includes taxes & fees
Feb 1 - Feb 2
Four Points by Sheraton Spartanburg

Comfort Inn & Suites Greer - Greenville

Comfort Inn & Suites Greer - Greenville
2.5 star property
Greer
8.6 out of 10, Excellent, (738)
"this is the best hotel friendly clean rooms, quiet and the staff is great."
United States
pamela
The price is P5,246
P5,718 total
includes taxes & fees
Jan 18 - Jan 19
Comfort Inn & Suites Greer - Greenville

Hampton Inn Greer Greenville, SC

Hampton Inn Greer Greenville, SC
2.5 star property
Greer
9.6 out of 10, Exceptional, (420)
"Very nice hotel! Clean! "
United States
Eric
The price is P8,182
P8,918 total
includes taxes & fees
Jan 4 - Jan 5
Hampton Inn Greer Greenville, SC

Inn @ Clemson

Inn @ Clemson
2.5 star property
Clemson
8.0 out of 10, Very Good, (1002)
"Staff and hotel was amazing "
United States
Keren
Inn @ Clemson

The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
Clemson
9.8 out of 10, Exceptional, (786)
"Everything was clean staff was courteous and accommodating. "
United States
Stewart
The price is P8,773
P9,737 total
includes taxes & fees
Jan 11 - Jan 12
The Inn at Patrick Square

The Abernathy of Clemson

The Abernathy of Clemson
4.0 star property
Clemson
9.6 out of 10, Exceptional, (559)
"location is amazing! "
United States
colleen
The Abernathy of Clemson

Woodspring Suites Greenville Airport

Woodspring Suites Greenville Airport
2.5 star property
Greenville
8.4 out of 10, Very Good, (316)
"All my stays have been good! No complaints "
United States
Sheila
The price is P4,650
P5,115 total
includes taxes & fees
Feb 2 - Feb 3
Woodspring Suites Greenville Airport

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
Clemson
8.2 out of 10, Very Good, (1001)
"Great area behind the hotel to walk my dog!!"
United States
Connie
The price is P6,039
P6,704 total
includes taxes & fees
Jan 13 - Jan 14
Comfort Inn & Suites Clemson - University Area

Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
Clemson
9.6 out of 10, Exceptional, (961)
"Great place to stay!"
United States
Mindi
The price is P8,770
P9,735 total
includes taxes & fees
Feb 1 - Feb 2
Clemson University's James F. Martin Inn

Hilton Garden Inn Spartanburg

Hilton Garden Inn Spartanburg
3.0 star property
Spartanburg
9.4 out of 10, Exceptional, (494)
"Very nice lady at check in"
United States
James
The price is P6,950
P7,715 total
includes taxes & fees
Jan 11 - Jan 12
Hilton Garden Inn Spartanburg

stayAPT Suites Greenville Greer BMW

stayAPT Suites Greenville Greer BMW
3.0 star property
Greer
8.8 out of 10, Excellent, (98)
"Very nice"
United States
Gitta
The price is P7,006
P7,917 total
includes taxes & fees
Jan 6 - Jan 7
stayAPT Suites Greenville Greer BMW

Courtyard Marriott Clemson

Courtyard Marriott Clemson
3.0 star property
Clemson
9.2 out of 10, Wonderful, (525)
"Overall, great stay!"
United States
Lynn
The price is P6,955
P7,720 total
includes taxes & fees
Jan 7 - Jan 8
Courtyard Marriott Clemson

Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG
3.5 star property
Greer
8.2 out of 10, Very Good, (816)
"Clean room, decent breakfast "
United States
Lorena
The price is P5,705
P6,276 total
includes taxes & fees
Jan 4 - Jan 5
Holiday Inn Express & Suites Greenville Airport by IHG

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
4.0 star property
Clemson
9.8 out of 10, Exceptional, (745)
"Staff was amazing and our room was clean and comfortable. "
United States
Amanda R
The price is P10,536
P11,695 total
includes taxes & fees
Jan 18 - Jan 19
The Shepherd Hotel Downtown Clemson

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
Clemson
8.2 out of 10, Very Good, (1001)
"Clean room and staff were great’"
United States
Audrey
The price is P5,455
P6,055 total
includes taxes & fees
Jan 5 - Jan 6
Best Western Plus Clemson Hotel & Conference Center

AC Hotel by Marriott Spartanburg

AC Hotel by Marriott Spartanburg
3.5 star property
Spartanburg
9.2 out of 10, Wonderful, (591)
"The gentleman at the front desk when I checked in made me feel very comfortable. He was so chill. It was a great stay"
United States
robert
The price is P7,955
P8,830 total
includes taxes & fees
Jan 18 - Jan 19
AC Hotel by Marriott Spartanburg

Comfort Suites Greenville Airport

Comfort Suites Greenville Airport
2.5 star property
Greenville
9.2 out of 10, Wonderful, (1009)
"We stayed here based on proximity to GSP airport. It was clean, parking lot was well lit, room was spacious and comfortable. Would stay here again."
United States
Lawrence
The price is P5,800
P6,554 total
includes taxes & fees
Jan 25 - Jan 26
Comfort Suites Greenville Airport

Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall
2.5 star property
Spartanburg
8.2 out of 10, Very Good, (1005)
"The room was great."
United States
Lacy
The price is P5,511
P6,117 total
includes taxes & fees
Jan 11 - Jan 12
Comfort Suites At WestGate Mall
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Showing deals for:Jan 16 - Jan 18
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Southeastern United States attractions

Learn more about Upstate South Carolina

Venture to sights like Discovery Island Water Park and Heritage Park as you discover Upstate South Carolina.

It is only a 1 mile hike to this beauty.  View a video about it here:  https://www.hdcarolina.com/episode/riley-moore-falls

#Waterfall
Photo by Ryan Watts
Open Photo by Ryan Watts

Top Upstate South Carolina Hotel Reviews

More cheap stays in Upstate South Carolina

Explore a world of travel with Expedia