The entrance to the Kentucky Science Center with a large circular structure in the foreground.

West Main Historic District Hotels near Louisville

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Next weekend
Oct 16 - Oct 18
In two weeks
Oct 23 - Oct 25

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Our top choices for West Main Historic District hotels

A modern interior with large windows offering a city view, a circular light fixture, and leather seating.

1. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (4,355 reviews)
"Great place to stay at"
United States
Saud
The price is P9,118
P10,728 total
includes taxes & fees
Oct 25 - Oct 26
Galt House Hotel Trademark Collection by Wyndham
A modern building with a restaurant on the ground floor, featuring large windows and outdoor seating.

2. Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (1,002 reviews)
"The room was clean and the hotel was in a great location."
United States
Veronica
The price is P13,993
P16,464 total
includes taxes & fees
Nov 7 - Nov 8
Louisville Marriott Downtown
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.

3. Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (2,177 reviews)
"This was the perfect location and wonderful place to stay"
United States
Samantha
The price is P15,957
P18,774 total
includes taxes & fees
Oct 30 - Oct 31
Omni Louisville Hotel
A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.

4. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (1,378 reviews)
"Excellent stay"
United States
Frances
The price is P9,221
P10,849 total
includes taxes & fees
Oct 29 - Oct 30
Embassy Suites Louisville Downtown
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.

5. Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,002 reviews)
"Nice hotel"
United States
Kelly
The price is P7,792
P9,168 total
includes taxes & fees
Oct 29 - Oct 30
Homewood Suites by Hilton Louisville Downtown, KY
A modern interior with a curved wall featuring vertical lines and geometric patterns.

6. Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
West Main Historic District
8.8 out of 10, Excellent, (1,832 reviews)
"Great place"
United States
Kenneth
The price is P7,162
P8,426 total
includes taxes & fees
Oct 30 - Oct 31
Holiday Inn Express & Suites Louisville Downtown by IHG
A spacious lobby with a central escalator, comfortable seating areas, and modern lighting fixtures.

7. Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
West Main Historic District
8.8 out of 10, Excellent, (1,008 reviews)
"Friendly staff, great location, easy parking, breakfast was good, clean"
United States
Lester
The price is P10,114
P11,900 total
includes taxes & fees
Oct 29 - Oct 30
Hyatt Regency Louisville
A classical gold statue in front of a multi-story building with large windows and a brick facade.

8. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,002 reviews)
"It was a great stay! The room and location were perfect, and the staff were very accommodating!"
United States
Matt
The price is P10,092
P12,189 total
includes taxes & fees
Nov 8 - Nov 9
21c Museum Hotel Louisville
A modern bar area with a circular bar, multiple seating options, and a large screen.

9. Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,004 reviews)
"Great hotel!"
United States
Gordon
The price is P6,785
P7,983 total
includes taxes & fees
Nov 9 - Nov 10
Cambria Hotel Louisville Downtown-Whiskey Row
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

10. The Grady

The Grady
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,004 reviews)
"I really enjoyed my stay and hope to return soon."
United States
Donna
The price is P11,647
P13,704 total
includes taxes & fees
Oct 18 - Oct 19
The Grady
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.

11. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
West Main Historic District
9.6 out of 10, Exceptional, (508 reviews)
"Great hotel, right in the middle of the city."
United States
Anthony
The price is P14,888
P17,517 total
includes taxes & fees
Oct 29 - Oct 30
Hotel Distil, Autograph Collection
An indoor dining area with wooden tables and chairs, a bar area, and a view of the street outside.

12. Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (1,004 reviews)
"We always enjoy our stay"
United States
Dolores
The price is P8,514
P10,017 total
includes taxes & fees
Nov 8 - Nov 9
Aloft by Marriott Louisville Downtown
A modern restaurant with hanging light fixtures, a bar area, and various seating options.

13. Hilton Garden Inn Louisville Downtown

Hilton Garden Inn Louisville Downtown
3.5 star property
West Main Historic District
8.4 out of 10, Very good, (1,000 reviews)
"This property is very conveniently located right around the corner from the Louisville palace theatre and very close to so many great restaurants. We enjoyed dinner and drinks at the rooftop restaurant as well as breakfast the next morning."
United States
Mike
The price is P6,645
P7,819 total
includes taxes & fees
Oct 25 - Oct 26
Hilton Garden Inn Louisville Downtown
An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.

14. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (162 reviews)
"Incredibly lovely location"
United States
Cameron
The price is P11,281
P13,274 total
includes taxes & fees
Oct 18 - Oct 19
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
A bar area with a neon 'CHECK IN' sign, a variety of liquor bottles, and a modern seating arrangement.

15. Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
West Main Historic District
9.2 out of 10, Wonderful, (848 reviews)
"Was a great place and great experience with the staff. Highly recommend this place"
United States
Bryan
The price is P8,041
P9,461 total
includes taxes & fees
Oct 25 - Oct 26
Moxy Louisville Downtown
An outdoor seating area with wicker furniture and a fire pit.

16. Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (797 reviews)
"Comfortable rooms within walking distance to breweries. Nice breakfast and friendly staff."
United States
Barbara
The price is P6,910
P8,131 total
includes taxes & fees
Oct 25 - Oct 26
Towneplace Suites By Marriott Louisville Downtown
A historic hotel with ornate architecture, a grand entrance, and a red carpet leading to the doors.

17. Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
West Main Historic District
8.8 out of 10, Excellent, (1,005 reviews)
"Great experience."
United States
DAVID
The price is P10,345
P12,172 total
includes taxes & fees
Oct 29 - Oct 30
Seelbach Hilton Louisville Downtown
A Courtyard by Marriott hotel with a modern brick facade, multiple floors, and a prominent sign.

18. Courtyard by Marriott Louisville Downtown

Courtyard by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.6 out of 10, Excellent, (1,002 reviews)
"Close to whiskey row."
United States
Patrick
The price is P8,127
P9,562 total
includes taxes & fees
Oct 25 - Oct 26
Courtyard by Marriott Louisville Downtown
A modern kitchen with wooden cabinets, a long countertop, and a variety of food items displayed.

19. SpringHill Suites by Marriott Louisville Downtown

SpringHill Suites by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.6 out of 10, Excellent, (1,002 reviews)
"The staff was super friendly and helpful. By far the best staff. Rooms were clean and showers were amazing"
United States
Beau
The price is P6,888
P8,105 total
includes taxes & fees
Nov 8 - Nov 9
SpringHill Suites by Marriott Louisville Downtown
A lobby with a reception desk, seating area, and a fireplace.

20. Fairfield Inn & Suites by Marriott Louisville Downtown

Fairfield Inn & Suites by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.4 out of 10, Very good, (1,003 reviews)
"Would stay again clean, affordable and located within walking distance to many restaurants."
United States
Natasha
The price is P6,354
P7,477 total
includes taxes & fees
Oct 25 - Oct 26
Fairfield Inn & Suites by Marriott Louisville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in West Main Historic District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.
Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
9.4
Exceptional
1,002 reviews
View
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.
Hotel Distil, Autograph Collection
4.0 star property
9.6
Exceptional
508 reviews
View
A modern bar area with a circular bar, multiple seating options, and a large screen.
Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
9.4
Exceptional
1,004 reviews
View
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.
The Grady
4.0 star property
9.4
Exceptional
1,004 reviews
View
A classical gold statue in front of a multi-story building with large windows and a brick facade.
21c Museum Hotel Louisville
4.5 star property
9.4
Exceptional
1,002 reviews
View

Where to stay in West Main Historic District

Find the best West Main Historic District areas and neighborhoods for the activities you enjoy most.
A steamboat docked at a pier with a bridge in the background.

Downtown Louisville

The cultural heart of the city beats with baseball, boxing and music, with sporting fields, live bands and a center for Muhammad Ali, the city’s most famous son.

A nighttime cityscape with a brightly lit bridge and a skyline featuring a prominent dome-shaped building.

St. Matthews

St. Matthews is noteworthy for its shopping, and you can make a stop at top attractions like Mall St. Matthews and Saint Matthews Pavilion Shopping Center.

A nighttime hot air balloon festival with colorful balloons, including one labeled "OLIVER WINERY."
Photo by Hyelsinta
Open Photo by Hyelsinta

Fairgrounds

While visiting Fairgrounds, you might make a stop by sights like Freedom Hall and Kentucky Kingdom.

A city skyline at dusk with illuminated buildings reflecting on the water.

Jeffersontown

Jeffersontown is known for its abundant dining options, and you can plan a trip to Jeffersontown Commons Shopping Center and Bluegrass Indoor Karting while you're in town.

A historical marker for the Conrad-Caldwell House, detailing its architectural style and history.

Old Louisville

Old Louisville is known for its abundant dining options, and you can plan a trip to Ohio River Valley and Asia Institute Crane House while you're in town.

Top West Main Historic District Hotel Reviews

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

10/10 Excellent
"Great place"
Phillip 2-night trip
Posted less than an hour ago
Galt House Hotel Trademark Collection by Wyndham

Frequently asked questions

What's it like in West Main Historic District?
Travelers love the West Main Historic District neighborhood for its beautiful river views, array of dining options, and sporting events. Are you looking for West Main Historic District travel tips? Be sure to check out Frazier International History Museum and Louisville Slugger Museum while you're in the neighborhood.
Where is the best hotel for a stay in West Main Historic District?
Based on our traveler data, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay in West Main Historic District. This hotel is a short 4-minute walk from KFC Yum Center, and it offers a full-service spa and 4 restaurants. Other good choices for your stay in the area include Holiday Inn Express & Suites Louisville Downtown by IHG and Omni Louisville Hotel.
How many hotels will I find in the West Main Historic District area?
If you're searching for places to stay in Louisville, Expedia has something to meet your needs with 234 West Main Historic District hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in West Main Historic District, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to get the best options available in West Main Historic District.
What is there to do around this Louisville neighborhood?
For cultural attractions in West Main Historic District, head to Flame Run Glass Studio and Gallery, Frazier International History Museum, and Louisville Slugger Museum. 21c Museum Hotel and Muhammad Ali Center are also a couple of places to visit in the neighborhood. Kentucky Peerless Distilling Co., Louisville Glassworks, and SAR Genealogical Research Library: NSSAR Library are just a few of the places to visit in and around West Main Historic District. While you're out sightseeing, Louisville Science Center and Kentucky Museum of Art and Craft are a couple of additional sights to visit in Louisville.