Midtown
St. Louis
Popular places to visit
St. Louis University
Explore the campus of St. Louis University as part of your travels around St. Louis. Wander around the area's picturesque gardens or experience its fascinating museums.
Scott Joplin House State Historic Site
Learn about the local history of St. Louis when you spend time at Scott Joplin House State Historic Site. Experience the area's great live music or attend a baseball game.
St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed theater scene or attend a baseball game.
Gateway Arch
Visit the Museum of Westward Expansion, then ascend to the top of the tallest man-made monument in the US for breathtaking views of St. Louis.
Enterprise Center
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
Downtown St. Louis Smartphone Guided Audio Walking Tour App
Lemp Haunted Neighborhood Walking Tour
St. Louis Premium Small Group Tour With Arch & River Cruise
Gateway Arch National Park Self Guided Audio Walking Tour
Top hotels in Midtown
Element St. Louis Midtown
Consistently clean, and staff are friendly.
Reviewed on Mar 18, 2026
Residence Inn by Marriott St Louis Downtown
Pulled out the sofa bed and stains all over. Third person (that I paid for was not able to sleep on the mattress). Took pictures showed to front desk and they took the pictures from my phone and said “ok” . Absolutely disgusting.
Reviewed on Mar 9, 2026
Drury Plaza Hotel St. Louis at the Arch
Great location and breakfast
Reviewed on Mar 21, 2026
Pear Tree Inn St. Louis Near Union Station
Good breakfast
Reviewed on Mar 21, 2026
Clayton Plaza Hotel & Extended Stay
Stay was wonderful. Would definitely recommend.
Reviewed on Mar 23, 2026
21C Museum Hotel St Louis
The room definitely needs to be updated. There were a lot of cracks, stains and the mattresses need to be replaced.
Reviewed on Mar 22, 2026
Other neighbourhoods around Midtown
The Gate
While there might not be top attractions in The Gate, you can explore the larger area and discover places like St. Louis Union Station and Enterprise Center.
Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and Enterprise Center are top sights worth seeing.
Lafayette Square
The restaurants and shopping are a few reasons travelers visit Lafayette Square. Though there aren't many top sights in the neighborhood, you can visit St. Louis Union Station and Enterprise Center, a few notable attractions nearby.
The Grove
The Grove might not have many top sights, but St. Louis Science Center and Missouri Botanical Gardens and Arboretum are two attractions nearby that you can check out.
Shaw
While there might not be top attractions in Shaw, you can explore the larger area and discover places like Missouri Botanical Gardens and Arboretum and St. Louis Science Center.
Central West End
If you're looking for things to see and do in Central West End, abundant dining options and forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.
