What is Midtown like?

Travelers are sure to enjoy a stay in St. Louis's Midtown neighborhood. Be sure to check out Chaifetz Arena and Washington Avenue Historic District as part of your Midtown travel plans.

Where is the best place to stay in Midtown?

Based on our traveler data, Element by Marriott St. Louis Midtown is one of the top choices for your stay in Midtown. This hotel is a short 6-minute walk from St. Louis University, and it offers free breakfast and an indoor pool.

How many hotels will I be able to find in the Midtown area?

If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 35 Midtown hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in Midtown, will I receive a refund?

Yes, most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and get a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get the best options available in Midtown.

What are the top things to see and do in Midtown?

Sights like Red Flag, Museum of Contemporary Religious Art, and Scott Joplin House State Historic Site can be part of your cultural tour of Midtown. Chaifetz Arena and Washington Avenue Historic District are also a couple of places to visit in the neighborhood. St. Louis Union Station and Enterprise Center are some favorite places to visit in the area around Midtown. While you're out sightseeing, Hermann Stadium and .ZACK Theater are a couple of additional sights to visit in St. Louis.

How can I get around Midtown and the greater St. Louis area?

Ready to get out and explore the city? Grand Station is the closest metro station.

Midtown Hotels, St. Louis

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for Midtown hotels

An outdoor patio area with seating, planters, and a grill.

1. Element by Marriott St. Louis Midtown

Midtown

Heather

P9,643 total

includes taxes & fees

Oct 4 - Oct 5

An outdoor patio area with seating, a fire pit, and a grill.

2. Residence Inn by Marriott St Louis Downtown

Midtown

Patrick

P8,173 total

includes taxes & fees

Oct 25 - Oct 26

A modern bar area with a wooden bar counter, black bar stools, and a large wall with city names.

3. Fairfield Inn & Suites by Marriott St. Louis Downtown

Downtown West, 1.3 km from Midtown

James

P9,311 total

includes taxes & fees

Oct 4 - Oct 5

An indoor swimming pool with a hot tub, lounge chairs, and a brick wall with artwork.

4. Pear Tree Inn St. Louis Near Union Station

Downtown West, 1.2 km from Midtown

Michael

P8,546 total

includes taxes & fees

Oct 1 - Oct 2

An indoor pool area with a hot tub, seating, and a stone wall.

5. Drury Plaza Hotel St. Louis Union Station

Downtown West, 1.5 km from Midtown

Robert

P10,030 total

includes taxes & fees

Oct 1 - Oct 2

A rooftop terrace with outdoor seating, string lights, and a city skyline view.

6. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

0.8 km from Midtown

Timothy

P8,700 total

includes taxes & fees

Oct 5 - Oct 6

A rooftop terrace with wicker furniture, offering a city view.

7. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis, 3.4 km from Midtown

Salvatore

P9,861 total

includes taxes & fees

Oct 1 - Oct 2

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

8. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 4.8 km from Midtown

Jennifer

P10,210 total

includes taxes & fees

Oct 4 - Oct 5

A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.

9. Embassy Suites by Hilton St. Louis Downtown

Downtown St. Louis, 3.1 km from Midtown

Karen

P8,469 total

includes taxes & fees

Oct 11 - Oct 12

A lobby with a sofa, two armchairs, a coffee table, and a staircase.

10. Hyatt Regency St. Louis at The Arch

Downtown St. Louis, 3.4 km from Midtown

David

P9,880 total

includes taxes & fees

Oct 2 - Oct 3

A modern outdoor seating area with a fire pit, surrounded by wicker furniture and a landscaped garden.

11. Courtyard by Marriott St. Louis Downtown West

Downtown West, 1.1 km from Midtown

Jonathan

P8,481 total

includes taxes & fees

Oct 11 - Oct 12

An outdoor dining area with a table and chairs, a neon sign, and a glass railing overlooking a cityscape.

12. Aloft by Marriott St Louis Central West End

Central West End, 2.2 km from Midtown

Jacob

P8,321 total

includes taxes & fees

Oct 4 - Oct 5

A modern outdoor lounge area with seating, a bar, and a view of a cityscape.

13. Live by Loews - St.Louis

Downtown St. Louis, 3 km from Midtown

Frank

P11,814 total

includes taxes & fees

Sep 27 - Sep 28

A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.

14. 21C Museum Hotel St Louis

Downtown West, 2.1 km from Midtown

Zane

P10,806 total

includes taxes & fees

Oct 18 - Oct 19

A modern kitchen with a hexagonal tile backsplash, built-in appliances, and a central island.

15. Tru By Hilton St. Louis Downtown

Downtown West, 2.5 km from Midtown

Shonda

P7,128 total

includes taxes & fees

Oct 4 - Oct 5

A hot tub with a wooden deck, surrounded by a bamboo fence, and string lights.

16. The West End

Central West End, 2.2 km from Midtown

Deborah

P7,028 total

includes taxes & fees

Sep 27 - Sep 28

A multi-story building with a classic architectural style, featuring numerous windows and a brick facade.

17. Courtyard by Marriott St. Louis Downtown/Convention Center

Downtown St. Louis, 2.9 km from Midtown

Kristy

P7,200 total

includes taxes & fees

Oct 25 - Oct 26

An indoor swimming pool with clear glass ceilings, large windows, and a sunlit area with umbrellas.

18. Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Downtown St. Louis, 3.5 km from Midtown

Andy

P7,727 total

includes taxes & fees

Oct 26 - Oct 27

A modern interior with hanging chairs and ottomans, large windows with a view of the street.

19. Home2 Suites by Hilton St. Louis Downtown

Downtown West, 2.5 km from Midtown

Erik

P7,128 total

includes taxes & fees

Oct 13 - Oct 14

A modern hotel room with a large bed, a nightstand, a mirror, and a view of the city through arched windows.

20. The Westin St. Louis

Downtown St. Louis, 2.9 km from Midtown

Joanne

P9,579 total

includes taxes & fees

Oct 18 - Oct 19

View all properties

Where to stay in Midtown

Find the best Midtown areas and neighborhoods for the activities you enjoy most.

The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch National Park or Kiener Plaza might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

See properties

A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

See properties

A fountain in front of a red brick building with green roofs and white trim.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

See properties

A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

St. Charles Historic District is known for its abundant dining options, and you can plan a trip to Historic Main Street and Missouri River while you're in town.

See properties

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

See properties

Top Midtown Hotel Reviews

Hollywood Casino & Hotel St. Louis

10/10 Excellent

"Staff was helpful. Clean rooms. Very accommodating."

Hyatt Regency St. Louis at The Arch

10/10 Excellent

"Upon check-in, unable to obtain our room key due to a hotel technology problem. An employee walked us to our room and later keys were finally delivered to us. We used the valet parking option which worked very well. The breakfast buffet had many good items, but some of the hot foods were cold. Overall staff was good."

Home2 Suites by Hilton St. Louis Downtown

8/10 Good

"Overall I had a positive experience because of the event occuring duriong the time of my visit. The staff was friendly, helpful and professtional. I was grateful after a long travel trip to be greeted by kind staff - reception, valet, security. Each very different and very helpful. Breakfast was fine both dayss. The surrounding area is was not desirable. We felt safe because our stay was during the Beatification of Archbishop Fulton Sheen so there was alot of traffic, cars and people everywhere. The condition of the front desk, lobby and rooms are very good. Disappointing was the hallway, up near the rooms. Unfortunately, the location is the only thing that would kept me from rebooking."

Midtown Hotels near St. Louis

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Midtown hotels

1. Element by Marriott St. Louis Midtown

2. Residence Inn by Marriott St Louis Downtown

3. Fairfield Inn & Suites by Marriott St. Louis Downtown

4. Pear Tree Inn St. Louis Near Union Station

5. Drury Plaza Hotel St. Louis Union Station

6. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

7. Drury Plaza Hotel St. Louis at the Arch

8. Hampton Inn & Suites St. Louis at Forest Park

9. Embassy Suites by Hilton St. Louis Downtown

10. Hyatt Regency St. Louis at The Arch

11. Courtyard by Marriott St. Louis Downtown West

12. Aloft by Marriott St Louis Central West End

13. Live by Loews - St.Louis

14. 21C Museum Hotel St Louis

15. Tru By Hilton St. Louis Downtown

16. The West End

17. Courtyard by Marriott St. Louis Downtown/Convention Center

18. Hampton Inn St. Louis-Downtown (At the Gateway Arch)

19. Home2 Suites by Hilton St. Louis Downtown

20. The Westin St. Louis

Where to stay in Midtown

Downtown St. Louis

Clayton

Central West End

St. Charles Historic District

Creve Coeur

Top Midtown Hotel Reviews

Hollywood Casino & Hotel St. Louis

Frequently asked questions

Explore a world of travel with Expedia