Mark Twain

St. Louis


Popular places to visit

Things to do


Top hotels in Mark Twain

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
The price is P7,817 per night from May 25 to May 26
P7,817
P9,219 total
May 25 - May 26
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (4,052 reviews)
Everything seemed more like a cheap motel. Room service came in a cardboard box. No one knew how to cast to the TV. All Apps and no service. No cash excepted. The valet did call a cab for us that was helpful everything else seemed sub-par.

Reviewed on May 17, 2026

Hyatt Regency St. Louis at The Arch
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
The price is P6,017 per night from Jun 1 to Jun 2
P6,017
P7,916 total
Jun 1 - Jun 2
includes taxes & fees
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.4/10 Very Good! (2,223 reviews)
Well I’m not a complainer, but we thought the casino was not the cleanest, empty beer cans full ashtrays and not sure when the last time a machine was wiped off. We went to the sports bar for a quick dinner and a couple of drinks the waitress was ok but they can’t answer a question. Never got the ...

Reviewed on May 17, 2026

Hollywood Casino & Hotel St. Louis
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
The price is P5,509 per night from May 24 to May 25
P5,509
P6,362 total
May 24 - May 25
includes taxes & fees
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,282 reviews)
Overall bad experience. Arrived for weekend stay on Friday at 330pm. Got in room and turned AC down low to get room cold. Put some perishables away in fridge for later. Then, left for evening plans and returned around midnight. Upon return room temp was 76 degrees, the AC had been turned off. Room ...

Reviewed on May 18, 2026

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
The price is P6,079 per night from Jun 7 to Jun 8
P6,079
P7,096 total
Jun 7 - Jun 8
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,201 reviews)
An event was occurring in the ballroom right above our room. It was after 9 pm and the room was bouncing and creaking with the dancing and hopping up and down, enough to feel like motion sickness. We requested to be moved and the staff person said they were fully booked, and was rude about the situation. ...

Reviewed on May 18, 2026

Clayton Plaza Hotel & Extended Stay
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
The price is P8,332 per night from May 21 to May 22
P8,332
P9,742 total
May 21 - May 22
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.8/10 Excellent! (1,967 reviews)
Good breakfast!

Reviewed on May 17, 2026

Pear Tree Inn St. Louis Near Union Station
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
The price is P9,197 per night from May 21 to May 22
P9,197
P10,759 total
May 21 - May 22
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.4/10 Very Good! (1,086 reviews)
I like this hotel but the air was out in the entire hotel my entire stay. A funny old folks home smell to it but overall it’s cool.

Reviewed on May 18, 2026

Renaissance St. Louis Airport Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Mark Twain

Central West End

Central West End

If you're looking for things to see and do in Central West End, abundant dining options and forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.

Central West End
St. Louis, Missouri - 08.22.2021 - Brookings Hall on the Danforth Campus of Washington University in St. Louis.

Midtown

While you're in Midtown, take in top sights like Chaifetz Arena and jump on the metro at Grand Station to see more of the city.

Midtown
The Grove

The Grove

The Grove might not have many top sights, but St. Louis Zoo and St. Louis Science Center are two attractions nearby that you can check out.

The Grove
Downtown West

Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

Downtown West
Default Image

The Gate

While there might not be top attractions in The Gate, you can explore the larger area and discover places like St. Louis Union Station and Busch Stadium.

The Gate
University City

University City

Noted for its shopping and restaurants, there's plenty to explore in University City. Top attractions like Heman Park Tennis Center and Museum of Transportation are major draws, and you can hop on the metro at Forsyth Station or U City Big Bend Station to see more of the city.

University City


Mark Twain