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Mark Twain Hotels near St. Louis

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Check prices for these dates

This weekend
Oct 16 - Oct 18
Next weekend
Oct 23 - Oct 25

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Our top choices for Mark Twain hotels

An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

1. Home2 Suites by Hilton St. Louis/Forest Park

Home2 Suites by Hilton St. Louis/Forest Park
3.0 star property
The Grove, 6.6 km from Mark Twain
8.6 out of 10, Excellent, (1,002 reviews)
"Staff was nice and helpful food was great and room was amazing!!! "
United States
paullita jeanne
The price is P9,758
P11,410 total
includes taxes & fees
Oct 18 - Oct 19
Home2 Suites by Hilton St. Louis/Forest Park
An indoor swimming pool with clear glass walls, blue lounge chairs, and a lifeguard stand.

2. Hampton Inn By Hilton St Louis Airport

Hampton Inn By Hilton St Louis Airport
2.5 star property
11.6 km from Mark Twain
9.0 out of 10, Wonderful, (241 reviews)
"Friendly staff, convenient location, quiet room, comfortable bed."
United States
Leia
The price is P8,083
P9,727 total
includes taxes & fees
Oct 29 - Oct 30
Hampton Inn By Hilton St Louis Airport
An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

3. Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park
3.5 star property
Dogtown, 7.4 km from Mark Twain
9.4 out of 10, Exceptional, (1,005 reviews)
The price is P8,697
P10,256 total
includes taxes & fees
Nov 9 - Nov 10
Hampton Inn & Suites St. Louis at Forest Park
A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

4. Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
2.5 star property
11.2 km from Mark Twain
9.2 out of 10, Wonderful, (1,006 reviews)
"This is a great place to stay at !"
United States
Daisy
The price is P6,903
P8,559 total
includes taxes & fees
Oct 19 - Oct 20
Hyatt Select St. Louis Airport
A modern bar area with a wooden bar counter, black bar stools, and a large wall with city names.

5. Fairfield Inn & Suites by Marriott St. Louis Downtown

Fairfield Inn & Suites by Marriott St. Louis Downtown
3.0 star property
Downtown West, 7.1 km from Mark Twain
9.2 out of 10, Wonderful, (1,006 reviews)
"Great central location for our desired attractions"
United States
Vicky
The price is P7,286
P8,687 total
includes taxes & fees
Nov 1 - Nov 2
Fairfield Inn & Suites by Marriott St. Louis Downtown
A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

6. Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
3.0 star property
12.6 km from Mark Twain
9.2 out of 10, Wonderful, (1,713 reviews)
"Staff was wonderful..great location with BBQ restaurant next door"
United States
Mary
The price is P6,075
P7,213 total
includes taxes & fees
Oct 19 - Oct 20
Wingate by Wyndham St. Louis Airport
A rooftop restaurant with round tables, chairs, and a view of the city.

7. Moonrise Hotel

Moonrise Hotel
4.0 star property
6.3 km from Mark Twain
9.0 out of 10, Wonderful, (2,042 reviews)
"Such a cute place to stay, and convenient to a music venue and restaurants."
United States
Jessie
The price is P9,192
P10,932 total
includes taxes & fees
Oct 19 - Oct 20
Moonrise Hotel
A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.

8. Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport
3.0 star property
11.9 km from Mark Twain
9.2 out of 10, Wonderful, (1,440 reviews)
"Excellent place to stay, highly recommend."
United States
Ethan
The price is P7,217
P8,540 total
includes taxes & fees
Oct 18 - Oct 19
Drury Inn & Suites St. Louis Airport
A courtyard with outdoor seating, a central fountain, and a view of a tower.

9. The Knight Center at Washington University

The Knight Center at Washington University
2.5 star property
7.5 km from Mark Twain
9.4 out of 10, Exceptional, (704 reviews)
The price is P9,554
P10,986 total
includes taxes & fees
Nov 1 - Nov 2
The Knight Center at Washington University
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

10. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End, 5.4 km from Mark Twain
9.2 out of 10, Wonderful, (1,008 reviews)
"The Sonesta is a lovely hotel with a beautiful pool. Our stay was a relaxing getaway and pleasant in every way."
United States
Kristina
The price is P10,104
P13,766 total
includes taxes & fees
Nov 1 - Nov 2
The Royal Sonesta Chase Park Plaza St. Louis
A modern hotel lobby with a reception desk, seating area, and a refreshment bar.

11. SpringHill Suites St. Louis Brentwood

SpringHill Suites St. Louis Brentwood
3.0 star property
11 km from Mark Twain
9.0 out of 10, Wonderful, (1,005 reviews)
"Staff was very friendly and rooms were clean."
United States
Aaron
The price is P7,851
P9,263 total
includes taxes & fees
Nov 1 - Nov 2
SpringHill Suites St. Louis Brentwood
A buffet with fruits, pastries, and beverages.

12. Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
10.3 km from Mark Twain
8.4 out of 10, Very good, (1,177 reviews)
"Great stay"
United States
Anthony
The price is P7,415
P8,675 total
includes taxes & fees
Oct 29 - Oct 30
Renaissance St. Louis Airport Hotel
The Clayton Plaza Hotel sign with a stone wall and plants in front.

13. Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
9.4 km from Mark Twain
8.8 out of 10, Excellent, (3,487 reviews)
"Great location, lots of things to do in the area and the staff was amazing!"
United States
Daniele
The price is P5,589
P6,525 total
includes taxes & fees
Oct 25 - Oct 26
Clayton Plaza Hotel & Extended Stay
A modern hotel room with a large bed, a desk with a chair, a blue armchair, a sofa, a TV, and a large window offering a city view.

14. DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park
4.0 star property
Central West End, 5.9 km from Mark Twain
8.4 out of 10, Very good, (1,000 reviews)
"Everything was good"
United States
may
The price is P9,334
P11,007 total
includes taxes & fees
Nov 1 - Nov 2
DoubleTree by Hilton St. Louis Forest Park
A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

15. Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
12.6 km from Mark Twain
9.2 out of 10, Wonderful, (3,288 reviews)
"Excellent stay"
United States
Murphy
The price is P5,648
P6,706 total
includes taxes & fees
Oct 18 - Oct 19
Pear Tree Inn St. Louis Airport
An outdoor patio with a fire pit, seating, and a building in the background.

16. Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
10.4 km from Mark Twain
9.4 out of 10, Exceptional, (910 reviews)
The price is P7,415
P9,044 total
includes taxes & fees
Oct 25 - Oct 26
Courtyard by Marriott St. Louis Brentwood
A snack kiosk with a variety of packaged foods and beverages, a cash register, and a sign reading 'The Shop.'

17. Hilton Garden Inn St. Louis Airport

Hilton Garden Inn St. Louis Airport
3.0 star property
7.8 km from Mark Twain
8.4 out of 10, Very good, (1,001 reviews)
"Great stay for being stranded to due weather conditions"
United States
Darryl
The price is P8,372
P9,794 total
includes taxes & fees
Oct 18 - Oct 19
Hilton Garden Inn St. Louis Airport
A rooftop terrace with outdoor seating, string lights, and a city skyline view.

18. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
5.6 km from Mark Twain
8.8 out of 10, Excellent, (1,176 reviews)
"Always our top pick to stay when in town for travel. Great people, Great vibes and a Great distance from alot of downtown hot spots ☺️"
United States
Skylee
The price is P7,925
P9,346 total
includes taxes & fees
Oct 18 - Oct 19
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.

19. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West, 7.2 km from Mark Twain
9.0 out of 10, Wonderful, (2,131 reviews)
"Great place to stay!"
United States
Zane
The price is P9,546
P11,475 total
includes taxes & fees
Oct 25 - Oct 26
21C Museum Hotel St Louis
A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

20. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
11.3 km from Mark Twain
9.6 out of 10, Exceptional, (1,003 reviews)
"Excellent place to stay. Beautiful hotel, amazing friendly and attentive staff. Would highly recommend!!"
United States
Janell
The price is P8,033
P9,540 total
includes taxes & fees
Nov 1 - Nov 2
Drury Plaza Hotel St. Louis Brentwood
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Mark Twain

Find the best Mark Twain areas and neighborhoods for the activities you enjoy most.
The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Old Courthouse or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

A historic building with a green dome and adjacent modern high-rise buildings.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

St. Charles Historic District is known for its abundant dining options, and you can plan a trip to Historic Main Street and Missouri River while you're in town.

Top Mark Twain Hotel Reviews

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

10/10 Excellent
"This hotel is located in a great location, close to the Gateway Arch and the ballpark where the Cardinals play. There were numerous fun restaurants within walking distance, and we felt safe except down by the Old Spaghetti Factory. I would stay in this hotel again and recommend it to others."
JAMES 2-night trip
Posted less than an hour ago
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Frequently asked questions

What's it like in Mark Twain?
Travelers will be sure to find plenty to entertain them in St. Louis's Mark Twain neighborhood.
If I need to cancel my hotel reservation in Mark Twain, will I receive a refund?
Yes, you'll find most room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get the best deals available in Mark Twain.
What is there to do around this St. Louis neighborhood?
Bellefontaine Cemetery, Calvary Cemetery, and Julia Davis Branch Library are just a few of the places to visit in and around Mark Twain. Shelley House and The Ville Monument are also worth a visit when you're out sightseeing in St. Louis.