Mark Twain Hotels near St. Louis

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Our top choices for Mark Twain hotels

Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
2.5 star property
11.2 km from Mark Twain
9.2 out of 10, Wonderful, (1,005 reviews)
"Great stay."
United States
Marty
The price is P7,283
P8,939 total
includes taxes & fees
Jun 1 - Jun 2
Hyatt Select St. Louis Airport

Holiday Inn Express Troy by IHG

Holiday Inn Express Troy by IHG
2.5 star property
28.8 km from Mark Twain
9.2 out of 10, Wonderful, (772 reviews)
"Great place to stay and get good sleep and an excellent breakfast."
United States
debbie
The price is P7,530
P8,357 total
includes taxes & fees
May 24 - May 25
Holiday Inn Express Troy by IHG

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 8.5 km from Mark Twain
9.4 out of 10, Exceptional, (3,420 reviews)
"Nice hotel, helpful staff, and excellent location."
United States
JEFF
The price is P10,492
P12,268 total
includes taxes & fees
May 22 - May 23
Drury Plaza Hotel St. Louis at the Arch

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
12.6 km from Mark Twain
9.4 out of 10, Exceptional, (2,999 reviews)
"Great room, staff, breakfast and location. "
United States
Elesia
The price is P6,357
P7,484 total
includes taxes & fees
Jun 18 - Jun 19
Pear Tree Inn St. Louis Airport

Super 8 by Wyndham Troy IL/St. Louis Area

Super 8 by Wyndham Troy IL/St. Louis Area
2.0 star property
28.6 km from Mark Twain
8.0 out of 10, Very Good, (1,002 reviews)
"Everything was great. We actually came here from walking out at a different hotel. This was a great place to stay with the family. "
United States
Virgil
The price is P4,459
P4,949 total
includes taxes & fees
May 28 - May 29
Super 8 by Wyndham Troy IL/St. Louis Area

The Principal Hotel

The Principal Hotel
3.5 star property
27.7 km from Mark Twain
9.8 out of 10, Exceptional, (266 reviews)
"Highly recommend will stay again!"
United States
Mark
The price is P6,963
P7,728 total
includes taxes & fees
May 19 - May 20
The Principal Hotel

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
25.5 km from Mark Twain
8.0 out of 10, Very Good, (1,280 reviews)
"Would stay here again."
United States
Randy
The price is P5,509
P6,362 total
includes taxes & fees
May 24 - May 25
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
3.0 star property
12.6 km from Mark Twain
9.2 out of 10, Wonderful, (1,600 reviews)
"Great room, breakfast, and staff. Would stay again! "
United States
Lilia
The price is P6,789
P7,994 total
includes taxes & fees
May 25 - May 26
Wingate by Wyndham St. Louis Airport

Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis
2.5 star property
22.1 km from Mark Twain
8.4 out of 10, Very Good, (849 reviews)
"Great place"
United States
Rogelio
The price is P6,506
P7,480 total
includes taxes & fees
May 24 - May 25
Comfort Inn Edwardsville - St. Louis

Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport
3.0 star property
11.9 km from Mark Twain
9.2 out of 10, Wonderful, (1,240 reviews)
"Clean room staff was great and the food was actually good."
United States
Benjamin
The price is P7,715
P9,052 total
includes taxes & fees
May 31 - Jun 1
Drury Inn & Suites St. Louis Airport

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
17.8 km from Mark Twain
9.0 out of 10, Wonderful, (1,555 reviews)
"Great place to stay!"
United States
Cassady
The price is P4,814
P6,497 total
includes taxes & fees
Jun 3 - Jun 4
River City Casino & Hotel

Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL
3.0 star property
29.9 km from Mark Twain
9.6 out of 10, Exceptional, (1,007 reviews)
"Rooms are clean and the staff is helpful and efficient."
United States
Mary
The price is P6,542
P7,587 total
includes taxes & fees
May 24 - May 25
Drury Inn & Suites St. Louis O'Fallon, IL

Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters
2.5 star property
29.8 km from Mark Twain
8.0 out of 10, Very Good, (1,005 reviews)
"Friendly staff. Comfy bed. Good breakfast. "
United States
Melanie
The price is P7,035
P8,085 total
includes taxes & fees
May 28 - May 29
Hampton Inn St. Charles St. Peters

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station
3.0 star property
Downtown West, 7 km from Mark Twain
8.8 out of 10, Excellent, (1,967 reviews)
"Stay here often always great "
United States
Laurie
The price is P7,529
P8,804 total
includes taxes & fees
May 31 - Jun 1
Pear Tree Inn St. Louis Near Union Station

Super 8 by Wyndham St Charles

Super 8 by Wyndham St Charles
2.0 star property
27.8 km from Mark Twain
8.0 out of 10, Very Good, (1,013 reviews)
"Great staff and great coffee."
United States
Kim
The price is P4,932
P5,668 total
includes taxes & fees
May 31 - Jun 1
Super 8 by Wyndham St Charles

Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG
2.5 star property
25.5 km from Mark Twain
9.2 out of 10, Wonderful, (869 reviews)
"Clean and very nice staff"
United States
Khanh
The price is P9,382
P10,787 total
includes taxes & fees
May 25 - May 26
Holiday Inn Express & Suites Edwardsville by IHG

Hilton St. Louis Airport

Hilton St. Louis Airport
3.5 star property
11.5 km from Mark Twain
7.6 out of 10, Good, (1,007 reviews)
"Great stay "
United States
Austin
The price is P8,866
P10,581 total
includes taxes & fees
May 29 - May 30
Hilton St. Louis Airport

Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66
3.0 star property
25.7 km from Mark Twain
7.8 out of 10, Good, (1,217 reviews)
"Clean and a safe place to stay"
United States
Cindy
The price is P5,246
P6,059 total
includes taxes & fees
May 19 - May 20
Wingate by Wyndham St. Louis/Fenton Route 66

Best Western St. Louis Inn

Best Western St. Louis Inn
2.5 star property
27.6 km from Mark Twain
8.2 out of 10, Very Good, (1,005 reviews)
"Nice clean economical place to stay with a very good breakfast "
United States
Henry
The price is P5,011
P5,762 total
includes taxes & fees
May 31 - Jun 1
Best Western St. Louis Inn

Drury Inn & Suites St. Louis Collinsville

Drury Inn & Suites St. Louis Collinsville
3.0 star property
20 km from Mark Twain
9.6 out of 10, Exceptional, (1,004 reviews)
"Hotel was welcoming, pool was nice for kids, meals were provided and access to highway was very good. Staff was excellent and helpful"
United States
Rick
The price is P6,851
P7,877 total
includes taxes & fees
May 28 - May 29
Drury Inn & Suites St. Louis Collinsville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mark Twain

Find the best Mark Twain areas and neighborhoods for the activities you enjoy most.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

Top Mark Twain Hotel Reviews

Frequently asked questions

What's it like in Mark Twain?
Travelers will be sure to find plenty to entertain them in St. Louis's Mark Twain neighborhood.
If I need to cancel my hotel reservation in Mark Twain, will I receive a refund?
Yes, you'll find most room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get the best deals available in Mark Twain.
What is there to do around this St. Louis neighborhood?
Bellefontaine Cemetery, Calvary Cemetery, and Julia Davis Branch Library are just a few of the places to visit in and around Mark Twain. Shelley House and The Ville Monument are also worth a visit when you're out sightseeing in St. Louis.