Mark Twain Hotels near St. Louis

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Our top choices for Mark Twain hotels

Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis
2.5 star property
25.3 km from Mark Twain
8.6 out of 10, Excellent, (684 reviews)
"Room was great,staff friendly! All together a great stay."
United States
Zachary
The price is P8,417
P9,678 total
includes taxes & fees
Apr 8 - Apr 9
Country Hearth Inn & Suites Edwardsville St. Louis

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
12.6 km from Mark Twain
9.4 out of 10, Exceptional, (2,891 reviews)
"Great stay, super clean and friendly staff."
United States
Edmarie
The price is P5,465
P6,434 total
includes taxes & fees
Apr 14 - Apr 15
Pear Tree Inn St. Louis Airport

Hampton Inn O'Fallon

Hampton Inn O'Fallon
2.5 star property
29.5 km from Mark Twain
9.2 out of 10, Wonderful, (831 reviews)
"We had a peaceful, clean and friendly stay. Very nice location. "
United States
Carl
The price is P6,663
P7,728 total
includes taxes & fees
Apr 3 - Apr 4
Hampton Inn O'Fallon

Holiday Inn Express Troy by IHG

Holiday Inn Express Troy by IHG
2.5 star property
28.8 km from Mark Twain
9.4 out of 10, Exceptional, (746 reviews)
"Shower was amazing, clean room, nice staff, decent breakfast"
United States
Paula
The price is P7,409
P8,223 total
includes taxes & fees
Apr 5 - Apr 6
Holiday Inn Express Troy by IHG

Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
2.5 star property
11.2 km from Mark Twain
9.2 out of 10, Wonderful, (1,003 reviews)
"The staff was friendly, pool hours were great and breakfast was satisfying "
United States
Charles
The price is P6,661
P8,192 total
includes taxes & fees
Apr 8 - Apr 9
Hyatt Select St. Louis Airport

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
25.5 km from Mark Twain
8.0 out of 10, Very Good, (1,174 reviews)
"Everything was great for overnight stay. "
United States
Regina
The price is P5,420
P6,260 total
includes taxes & fees
Apr 5 - Apr 6
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
17.8 km from Mark Twain
9.0 out of 10, Wonderful, (1,507 reviews)
"Great place with lots of restaurants "
United States
Dennis
The price is P6,558
P8,519 total
includes taxes & fees
Apr 2 - Apr 3
River City Casino & Hotel

Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
2.5 star property
12.6 km from Mark Twain
9.2 out of 10, Wonderful, (1,570 reviews)
"Great location room was nice and clean "
United States
Gabriela
The price is P6,614
P7,787 total
includes taxes & fees
Apr 5 - Apr 6
Wingate by Wyndham St. Louis Airport

Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites Southwest St. Louis
3.0 star property
27.9 km from Mark Twain
9.6 out of 10, Exceptional, (1,002 reviews)
"Very clean place with great food and friendly staff. "
Canada
Kara
The price is P7,206
P8,430 total
includes taxes & fees
Apr 19 - Apr 20
Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport
3.0 star property
11.9 km from Mark Twain
9.2 out of 10, Wonderful, (1,165 reviews)
"Great stay! Clean and food was great "
United States
Mary
The price is P6,983
P8,194 total
includes taxes & fees
Apr 5 - Apr 6
Drury Inn & Suites St. Louis Airport

Super 8 by Wyndham Troy IL/St. Louis Area

Super 8 by Wyndham Troy IL/St. Louis Area
2.0 star property
28.6 km from Mark Twain
8.0 out of 10, Very Good, (1,006 reviews)
"Was good for the night! "
United States
Bryce
The price is P4,375
P4,856 total
includes taxes & fees
Apr 8 - Apr 9
Super 8 by Wyndham Troy IL/St. Louis Area

Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield
3.0 star property
28.1 km from Mark Twain
9.8 out of 10, Exceptional, (1,117 reviews)
"It’s a great place very happy!"
United States
Chris
The price is P7,894
P9,156 total
includes taxes & fees
Apr 4 - Apr 5
Drury Plaza Hotel St. Louis Chesterfield

Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold
2.5 star property
29.7 km from Mark Twain
9.4 out of 10, Exceptional, (1,000 reviews)
"Will definitely stay here again! "
United States
Sharon
The price is P5,449
P6,300 total
includes taxes & fees
Apr 19 - Apr 20
Pear Tree Inn St. Louis Arnold

Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG
2.5 star property
25.5 km from Mark Twain
9.2 out of 10, Wonderful, (855 reviews)
"Very pleasant and accommodating. "
United States
Diana
The price is P8,720
P10,026 total
includes taxes & fees
Apr 19 - Apr 20
Holiday Inn Express & Suites Edwardsville by IHG

Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO
2.0 star property
15.8 km from Mark Twain
8.6 out of 10, Excellent, (1,896 reviews)
"Great place to stay"
United States
Kerry
The price is P3,943
P4,820 total
includes taxes & fees
Apr 19 - Apr 20
Motel 6 Hazelwood, MO

The Principal Hotel

The Principal Hotel
3.5 star property
27.7 km from Mark Twain
9.8 out of 10, Exceptional, (222 reviews)
"I love staying here whenever i come to town."
United States
bonnie
The price is P6,831
P7,582 total
includes taxes & fees
Apr 9 - Apr 10
The Principal Hotel

Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters
2.5 star property
29.8 km from Mark Twain
8.0 out of 10, Very Good, (1,004 reviews)
"Everything was great as always at this location as i have stayed here many times"
United States
Gregory
The price is P6,424
P7,383 total
includes taxes & fees
Apr 12 - Apr 13
Hampton Inn St. Charles St. Peters

Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
Berkeley, 10.3 km from Mark Twain
8.4 out of 10, Very Good, (1,069 reviews)
"Great place to stay "
United States
Timothy
The price is P8,441
P9,876 total
includes taxes & fees
Apr 14 - Apr 15
Renaissance St. Louis Airport Hotel

Drury Plaza Hotel St. Louis Creve Coeur

Drury Plaza Hotel St. Louis Creve Coeur
3.0 star property
Creve Coeur, 18 km from Mark Twain
9.2 out of 10, Wonderful, (1,009 reviews)
"Great stay! "
United States
Amy
The price is P7,206
P8,376 total
includes taxes & fees
Apr 5 - Apr 6
Drury Plaza Hotel St. Louis Creve Coeur

Best Western Plus Fenton

Best Western Plus Fenton
2.5 star property
24.3 km from Mark Twain
9.2 out of 10, Wonderful, (245 reviews)
"Easy parking, friendly staff, clean and comfy rooms. "
United States
Jan
The price is P6,533
P7,545 total
includes taxes & fees
Apr 16 - Apr 17
Best Western Plus Fenton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mark Twain

Find the best Mark Twain areas and neighborhoods for the activities you enjoy most.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and Enterprise Center are top sights worth seeing.

Berkeley

Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

Top Mark Twain Hotel Reviews

Frequently asked questions

What's it like in Mark Twain?
Travelers will be sure to find plenty to entertain them in St. Louis's Mark Twain neighborhood.
If I need to cancel my hotel reservation in Mark Twain, will I receive a refund?
Yes, you'll find most room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get the best deals available in Mark Twain.
What is there to do around this St. Louis neighborhood?
Bellefontaine Cemetery, Calvary Cemetery, and Julia Davis Branch Library are just a few of the places to visit in and around Mark Twain. Shelley House and The Ville Monument are also worth a visit when you're out sightseeing in St. Louis.