Mark Twain
St. Louis
Visit Mark Twain
Popular places to visit
St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.
Gateway Arch
Visit the Museum of Westward Expansion, then ascend to the top of the tallest man-made monument in the US for breathtaking views of St. Louis.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Enterprise Center
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.
Washington University in St. Louis
Enjoy the collegiate vibe at Washington University in St. Louis during your stay in St. Louis. Amble around the area's lush forest or attend a sporting event.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
Downtown St. Louis Smartphone Guided Audio Walking Tour App
St. Louis Premium Small Group Tour With Arch & River Cruise
Gateway Arch National Park Self Guided Audio Walking Tour
Top hotels in Mark Twain
21C Museum Hotel St Louis
Beautiful, unique hotel. Loved the esthetics and vibe of the entire building.
Reviewed on Feb 7, 2026
Clayton Plaza Hotel & Extended Stay
Cleanliness, staff nice
Reviewed on Feb 7, 2026
Pear Tree Inn St. Louis Airport
It was wonderful
Reviewed on Feb 7, 2026
Drury Plaza Hotel St. Louis at the Arch
Clean, spacious, amenities and location everything was on point. The FREE breakfast and complimentary evening snacks were all delicious! Friendly staff made us feel welcome
Reviewed on Feb 4, 2026
Hyatt Regency St. Louis at The Arch
Yes
Reviewed on Feb 6, 2026
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Nice clean rooms and friendly staff. Oh, the cookies were delicious 😋.
Reviewed on Feb 4, 2026
Other neighbourhoods around Mark Twain
Central West End
If you're looking for things to see and do in Central West End, abundant dining options and forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.
Midtown
While you're in Midtown, take in top sights like Chaifetz Arena and jump on the metro at Grand Station to see more of the city.
The Grove
The Grove might not have many top sights, but St. Louis Science Center and Missouri Botanical Gardens and Arboretum are two attractions nearby that you can check out.
Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.
The Gate
While there might not be top attractions in The Gate, you can explore the larger area and discover places like St. Louis Union Station and Busch Stadium.
University City
Noted for its shopping and restaurants, there's plenty to explore in University City. Top attractions like Museum of Transportation and Center of Creative Arts are major draws, and you can hop on the metro at Forsyth Station or U City Big Bend Station to see more of the city.
