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Business Hotels in Southeast Missouri, Missouri

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Check availability on Southeast Missouri Business Hotels

Tonight
Sep 28 - Sep 29
Tomorrow
Sep 29 - Sep 30
This weekend
Oct 2 - Oct 4
Next weekend
Oct 9 - Oct 11

Our top choices for Southeast Missouri business-friendly hotels

A motel with a covered entrance, a flag, and a phone number.
A hotel room with two beds, a desk, a chair, a TV, and a bathroom.
A spacious kitchen with a dining area, featuring a ceiling fan, a TV mounted on the wall, and a large rug in the center.
A reception desk with a wooden finish, a framed black and white cityscape, and a large framed Eiffel Tower picture.

1. Madison Inn Lodge

Madison Inn Lodge
Fredericktown
United States
Bawan
P5,467
P5,972 total
includes taxes & fees
Oct 21 - Oct 22
Madison Inn Lodge
A kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, a stove, and a granite countertop.
A hotel room with two beds, a lamp, and a painting on the wall.
A building with a red awning labeled "Shepherd Mountain Inn."
A bathroom with a white sink, a large mirror, a hairdryer, a coffee maker, and a microwave.

2. Shepherd Mountain Inn

Shepherd Mountain Inn
Ironton
United States
Michael
P7,703
P8,414 total
includes taxes & fees
Oct 6 - Oct 7
Shepherd Mountain Inn
A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.
A hotel room with two beds, a brick wall, and a wooden headboard.
An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.
A restaurant with a brick wall, a flat-screen TV, and a bar area.

3. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
Jackson
United States
Thomas
P5,247
P5,548 total
includes taxes & fees
Oct 11 - Oct 12
Drury Inn & Suites Jackson MO
A dining area with tables and chairs, a kitchen area, and a TV mounted on the wall.
A hotel reception area with a glass partition, a reception desk, and a digital kiosk.
A parking lot with a tree in bloom, a red fire hydrant, and a building in the background.
A gym with cardio equipment, a bench press, and a squat rack.

4. Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
Farmington
United States
Joseph
P3,549
P3,863 total
includes taxes & fees
Oct 25 - Oct 26
Baymont Inn and Suites by Wyndham Farmington, MO
A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.
Snack bar
Pool
Exterior

5. Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
Poplar Bluff
United States
Rhonda
P5,488
P6,145 total
includes taxes & fees
Oct 18 - Oct 19
Hampton Inn Poplar Bluff
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

6. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
United States
Sandra
P6,247
P7,047 total
includes taxes & fees
Oct 7 - Oct 8
Drury Plaza Hotel Cape Girardeau Conference Center
A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.
A hotel room with two beds, a nightstand, a lamp, and a chair.
A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.
A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

7. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Jackson
United States
Elaine
P5,257
P5,690 total
includes taxes & fees
Oct 1 - Oct 2
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
A hotel room with a bed, a sofa, a desk, and a chair.
A hotel lobby with a central reception desk, multiple seating areas, and a tiled floor.
A modern living room with a sofa, armchairs, a coffee table, and a painting on the wall.
An indoor swimming pool with a tiled edge, surrounded by lounge chairs and potted plants.

8. Holiday Inn Express & Suites Farmington by IHG

Holiday Inn Express & Suites Farmington by IHG
Farmington
United States
Sheila
P7,372
P8,024 total
includes taxes & fees
Oct 4 - Oct 5
Holiday Inn Express & Suites Farmington by IHG
An indoor swimming pool with a brick border, wooden walls, and a view of the outdoors.
A spacious hotel lobby with a dining area, kitchen, and large windows.
A modern bathroom with a bathtub, a window with curtains, and a view of a green landscape.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

9. Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection
Farmington
United States
Susan
P6,850
P7,457 total
includes taxes & fees
Oct 14 - Oct 15
Crown Pointe Lodge, BW Signature Collection
A spacious lobby with a curved staircase, large windows, and a seating area with a rug.
A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.
A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.
A modern outdoor seating area with a fire feature, a stone wall, and a view of the sunset.

10. The Riverview

The Riverview
Cape Girardeau
United States
Alyssa
P7,141
P8,056 total
includes taxes & fees
Sep 30 - Oct 1
The Riverview
View all properties

Top Southeast Missouri Hotel Reviews

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

8/10 Good
"Staff was friendly, especially in the dining area. Breakfast included was good, but limited selection. Central location with easy access and parking."
Raymond 4-night trip
Posted 2 hours ago
Pear Tree Inn Cape Girardeau West
Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

10/10 Excellent
"Staff were helpful."
Joseph 1-night trip
Posted 1 day ago
Baymont Inn and Suites by Wyndham Farmington, MO
Drury Inn & Suites Hayti Caruthersville

Drury Inn & Suites Hayti Caruthersville

10/10 Excellent
"Great experience. Staff was welcoming. Rooms were clean."
yolanda 2-night trip
Posted 1 day ago
Drury Inn & Suites Hayti Caruthersville
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"Clean room and perfect stay. We have come to consistently appreciate Drury brand for a quality stay. We would definitely recommend this location for clean comfortable accommodations."
Hiram 1-night trip
Posted 6 days ago
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

10/10 Excellent
"Clean room, staff"
Lavonne 2-night trip
Posted 6 days ago
Drury Inn & Suites Poplar Bluff
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent
"This was a very good value. It has been the best hotel I've stayed at in awhile."
David 1-night trip
Posted 7 days ago
Days Inn and Suites by Wyndham Sikeston

Frequently asked questions

How much do business-friendly hotels in Southeast Missouri cost?
Rates for business hotels in Southeast Missouri range between P3,863 and P8,414 per night. No matter your budget, Expedia is here to help you find the perfect place to get the job done. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Southeast Missouri?
Southeast Missouri has multiple business-friendly hotels with a total average guest review rating of 8.8. Attending a work-related event in Cape Girardeau? Hampton Inn Cape Girardeau I 55 East is a 2.5-stars stay that comes highly recommended by corporate travelers and includes a dining venue and a terrace. Another excellent choice for a business trip is Drury Plaza Hotel Cape Girardeau Conference Center. Also in Cape Girardeau, it has a 3-stars rating and amenities such as a swimming pool and a restaurant.
How many business-friendly hotels are there in Southeast Missouri?
Southeast Missouri has 50 business-friendly hotels to pick from. Whether you're meeting with new clients or working remotely, these stays come with the services and amenities you need to be productive.
What are the best cheap business-friendly hotels in Southeast Missouri?
When you're on the road for work in Southeast Missouri, Expedia will help you find the ideal business-friendly hotel. Hampton Inn Cape Girardeau I 55 East is a budget pick in Cape Girardeau. A dining venue and a swimming pool are some of its many amenities. Seeking affordable stays in Sikeston? Pear Tree Inn Sikeston is recommended by many corporate travelers. It offers conveniences that make it easy to both work and play, such as a swimming pool and a spa tub. Business-friendly hotels in Southeast Missouri start at just P3,863 a night. You'll find tons of fabulous and free attractions wherever you're off to in Southeast Missouri. If you're meeting with clients in Cape Girardeau, try to make time in your schedule for Hunter Valley Winery. You can also see the sights without spending a penny in Sikeston. Sikeston Depot Museum is one of the most popular free things to do here. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Are there any family-friendly hotels in Southeast Missouri that are also business friendly?
There sure are. Whether you're searching for a stay in Southeast Missouri with a conference room or a quiet space to work alone, con espacio para trabajar Expedia's got you sorted. Drury Plaza Hotel Cape Girardeau Conference Center in Cape Girardeau is a fantastic choice. This 3-stars business and family-friendly option comes with all the necessary conveniences, like complimentary breakfast and housekeeping services. Pear Tree Inn Cape Girardeau West is another option in Cape Girardeau where corporate travelers can get some work done with the family in tow. Complimentary breakfast and a laundry service are among the many amenities at this 2.5-stars hotel. When you've finished work, it's time to discover Cape Girardeau with the kids. Popular family-friendly attractions include Cape Splash Family Aquatic Center and Lazy L Safari Park.
Why book your business-friendly hotel in Southeast Missouri with Expedia?
Expedia is here to help you find an ideal business-friendly hotel when work takes you away from home. From meeting rooms and conference spaces to gyms and on-site restaurants, our stays have all the amenities you'll need to settle that big contract.
How can I find cheap business-friendly hotels in Southeast Missouri?
Select the "business friendly" filter, located under the "traveler experience" heading, to find cheap business-friendly hotels in Southeast Missouri. Then fine-tune your search by your per-night budget. Basing yourself outside the city center is another easy way to save.
What is there to do in Southeast Missouri near my business-friendly hotel?
The most important accessory for your Southeast Missouri work visit is an epic itinerary for your downtime! Isle Casino Cape Girardeau, Show Me Center and Riverfront Park are among the top sights if you're headed to Cape Girardeau. Sikeston is also home to terrific attractions, such as Sikeston Depot Museum, Central Park and The Book Bug.

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