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Business Hotels in Southeast Missouri, Missouri
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Top Southeast Missouri Business Hotels

Echo Bluff State Park
Eminence
9.6 out of 10, Exceptional, (214)
The price is P9,390
P9,927 total
includes taxes & fees
Nov 17 - Nov 18

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
9.6 out of 10, Exceptional, (1005)
The price is P5,314
P5,995 total
includes taxes & fees
Dec 1 - Dec 2

Drury Inn & Suites Sikeston, MO
Sikeston
9.4 out of 10, Exceptional, (1003)
The price is P5,669
P6,518 total
includes taxes & fees
Nov 20 - Nov 21

Holiday Inn Express & Suites Perryville by IHG
Perryville
9.2 out of 10, Wonderful, (529)
The price is P5,610
P6,422 total
includes taxes & fees
Nov 23 - Nov 24

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Jackson
8.8 out of 10, Excellent, (650)
The price is P4,969
P5,378 total
includes taxes & fees
Nov 17 - Nov 18

Drury Inn & Suites Poplar Bluff
Poplar Bluff
9.2 out of 10, Wonderful, (945)
The price is P5,551
P6,270 total
includes taxes & fees
Nov 23 - Nov 24

Fairfield Inn & Suites by Marriott Poplar Bluff
Poplar Bluff
9.4 out of 10, Exceptional, (837)
The price is P6,142
P6,939 total
includes taxes & fees
Dec 1 - Dec 2

Holiday Inn Poplar Bluff by IHG
Poplar Bluff
8.8 out of 10, Excellent, (686)
The price is P5,965
P6,738 total
includes taxes & fees
Nov 23 - Nov 24
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Southeast Missouri Hotel Reviews
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
10/10 Excellent
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Hotel Theme
- Budget Hotels in Southeast Missouri
- Casino Hotels in Southeast Missouri
- Family friendly Hotels in Southeast Missouri
- Golf Hotels in Southeast Missouri
- Hotels near Shopping Areas in Southeast Missouri
- Hotels with Air Conditioning in Southeast Missouri
- Hotels with Balcony in Southeast Missouri
- Hotels with Bars / Lounges in Southeast Missouri
- Hotels with Breakfast in Southeast Missouri
- Hotels with Entertainment in Southeast Missouri
- Hotels with Gyms in Southeast Missouri
- Hotels with Hot Tubs in Southeast Missouri
- Hotels with Internet in Southeast Missouri
- Hotels with Restaurants in Southeast Missouri
- Hotels with Spa in Southeast Missouri
- Hotels with Swimming Pool in Southeast Missouri
- Hotels with Views in Southeast Missouri
- Hotels with WiFi in Southeast Missouri
- Hotels with connecting rooms in Southeast Missouri
- Hotels with free Internet in Southeast Missouri
- Hotels with free breakfast in Southeast Missouri
- Hotels with free parking in Southeast Missouri
- Hotels with free wifi in Southeast Missouri
- Hotels with indoor pool in Southeast Missouri
- Hotels with parking in Southeast Missouri
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- Hotels with smoking rooms in Southeast Missouri
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- Pet friendly Hotels in Southeast Missouri
- Romantic Hotels in Southeast Missouri
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Most Popular Hotels in Southeast Missouri
- Tru By Hilton Cape Girardeau
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
- Days Inn and Suites by Wyndham Sikeston
- Fairfield Inn & Suites by Marriott Poplar Bluff
- Drury Inn & Suites Cape Girardeau
- Fairfield Inn & Suites by Marriott Cape Girardeau
- Drury Inn & Suites Hayti Caruthersville
- Hampton Inn Poplar Bluff



































