Hotels near South Texas Medical Center

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 30 - Dec 31
Tomorrow
Dec 31 - Jan 1
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Filter by

Guest rating
Guest rating
Star rating

Our top choices for South Texas Medical Center hotels

Pool
Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center
2.5 star property
Medical Center District, 1 km from South Texas Medical Center
9.0 out of 10, Wonderful, (1009)
"Everything was great, staff really kind ..."
United States
traci
The price is P5,405
P6,310 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Fairfield Inn & Suites by Marriott San Antonio Medical Center
Exterior
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District, 1.3 km from South Texas Medical Center
8.8 out of 10, Excellent, (1008)
"Clean room, very close to medical center, and personnel at check in were very friendly."
United States
Melinda
The price is P5,228
P6,181 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Courtyard by Marriott Medical Center San Antonio
Lobby
Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District, 2.9 km from South Texas Medical Center
9.2 out of 10, Wonderful, (1292)
"Great place to stay and visit "
United States
Harry
The price is P5,287
P6,249 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Drury Inn & Suites San Antonio Northwest Medical Center
Front of property
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District, 2.4 km from South Texas Medical Center
8.4 out of 10, Very Good, (3144)
"Great place "
United States
Amado
The price is P5,217
P6,166 total
includes taxes & fees
Dec 31 - Jan 1, 2026
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Premium bedding, pillowtop beds, in-room safe, desk
SpringHill Suites by Marriott San Antonio Medical Center/NW

SpringHill Suites by Marriott San Antonio Medical Center/NW

SpringHill Suites by Marriott San Antonio Medical Center/NW
3.0 star property
Medical Center District, 3.2 km from South Texas Medical Center
8.8 out of 10, Excellent, (1001)
"good staff. good stay"
United States
Divya
The price is P5,933
P7,014 total
includes taxes & fees
Jan 2 - Jan 3, 2026
SpringHill Suites by Marriott San Antonio Medical Center/NW
Indoor pool, outdoor pool
The Westin San Antonio North

The Westin San Antonio North

The Westin San Antonio North
4.0 star property
3.2 km from South Texas Medical Center
8.6 out of 10, Excellent, (1235)
"Love this hotel!"
United States
Nora
The price is P4,855
P5,827 total
includes taxes & fees
Jan 9 - Jan 10, 2026
The Westin San Antonio North
Reception
Park Inn by Radisson

Park Inn by Radisson

Park Inn by Radisson
2.0 star property
Medical Center District, 0.9 km from South Texas Medical Center
7.2 out of 10, Good, (1003)
"Staff were amazing, and everything else was great too. "
United States
Maximilian
The price is P3,545
P4,139 total
includes taxes & fees
Jan 23 - Jan 24, 2026
Park Inn by Radisson
Front of property
Atria Inn & Suites

Atria Inn & Suites

Atria Inn & Suites
2.0 star property
Medical Center District, 2.2 km from South Texas Medical Center
7.4 out of 10, Good, (275)
"Nice, comfortable space for a reasonable price. "
United States
Cynthia
Atria Inn & Suites
Desk, laptop workspace, blackout drapes, free WiFi
Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center
2.0 star property
Medical Center District, 2.7 km from South Texas Medical Center
7.2 out of 10, Good, (223)
"Good stay and safe area"
United States
Mario
The price is P2,868
P3,348 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Studio 6 San Antonio, Tx - Northwest Medical Center
Exterior
OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio
2.0 star property
Medical Center District, 3.1 km from South Texas Medical Center
7.2 out of 10, Good, (228)
"Staff was courteous and professional and the room is nice."
United States
Thomas
The price is P3,172
P3,909 total
includes taxes & fees
Jan 14 - Jan 15, 2026
OYO Inn & Suites Medical Center San Antonio
Free daily on-the-go breakfast
Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Country Inn & Suites by Radisson, San Antonio Medical Center, TX
3.0 star property
Medical Center District, 2.6 km from South Texas Medical Center
6.8 out of 10, (1005)
"Clean room and great customer service "
United States
roel
The price is P3,446
P4,023 total
includes taxes & fees
Jan 28 - Jan 29, 2026
Country Inn & Suites by Radisson, San Antonio Medical Center, TX
Desk, laptop workspace, free WiFi, bed sheets
Studio 6 San Antonio, TX - Medical Center

Studio 6 San Antonio, TX - Medical Center

Studio 6 San Antonio, TX - Medical Center
2.0 star property
Medical Center District, 1.3 km from South Texas Medical Center
6.6 out of 10, (796)
"Staff and amenities "
United States
Keyshia
The price is P2,799
P3,427 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Studio 6 San Antonio, TX - Medical Center
Lounge
Motel 6 San Antonio, TX - Fiesta Trails

Motel 6 San Antonio, TX - Fiesta Trails

Motel 6 San Antonio, TX - Fiesta Trails
2.0 star property
2.9 km from South Texas Medical Center
6.6 out of 10, (981)
"Our stay was very pleasant. TY ANNA FOR OUR CHECK-IN"
United States
Joben
The price is P2,805
P3,275 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Motel 6 San Antonio, TX - Fiesta Trails
Desk, iron/ironing board, free WiFi, bed sheets
Flex Studios

Flex Studios

Flex Studios
2.5 star property
Medical Center District, 2.7 km from South Texas Medical Center
6.0 out of 10, (498)
"heb is nearby. "
United States
Sayeed
The price is P2,432
P2,875 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Flex Studios
Free WiFi, bed sheets
Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center
2.0 star property
Medical Center District, 2.8 km from South Texas Medical Center
6.0 out of 10, (1001)
"Great experience "
United States
John
The price is P2,511
P2,969 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Motel 6 San Antonio, TX - Northwest Medical Center
Lobby
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District, 3.3 km from South Texas Medical Center
8.6 out of 10, Excellent, (1007)
"Best hotel!"
United States
Valeria
The price is P6,442
P7,655 total
includes taxes & fees
Jan 2 - Jan 3, 2026
San Antonio Marriott Northwest Medical Center
Outdoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, sun loungers
Homewood Suites by Hilton San Antonio Northwest

Homewood Suites by Hilton San Antonio Northwest

Homewood Suites by Hilton San Antonio Northwest
3.0 star property
3.3 km from South Texas Medical Center
8.4 out of 10, Very Good, (1002)
"Everything was great. Close to the zoo and Riverwalk. "
United States
Elizabeth
The price is P4,287
P5,068 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Homewood Suites by Hilton San Antonio Northwest
Lobby sitting area
Hyatt Place San Antonio-Northwest/Medical Center

Hyatt Place San Antonio-Northwest/Medical Center

Hyatt Place San Antonio-Northwest/Medical Center
3.0 star property
3.4 km from South Texas Medical Center
8.2 out of 10, Very Good, (1010)
"Really enjoyed our stay. "
United States
Juan
The price is P4,447
P5,329 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Hyatt Place San Antonio-Northwest/Medical Center
Exterior
Sonesta ES Suites San Antonio Northwest - Medical Center

Sonesta ES Suites San Antonio Northwest - Medical Center

Sonesta ES Suites San Antonio Northwest - Medical Center
3.0 star property
3.3 km from South Texas Medical Center
8.2 out of 10, Very Good, (1003)
"Very good value. Clean, respectful staff, nice breakfast "
United States
Mary Jo
The price is P3,936
P4,653 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Sonesta ES Suites San Antonio Northwest - Medical Center
Porch
TownePlace Suites by Marriott San Antonio Northwest

TownePlace Suites by Marriott San Antonio Northwest

TownePlace Suites by Marriott San Antonio Northwest
3.0 star property
3.7 km from South Texas Medical Center
8.2 out of 10, Very Good, (1002)
"It is a good stay. We enjoyed a lot..."
United States
ARUNKUMAR
The price is P4,700
P5,654 total
includes taxes & fees
Jan 1 - Jan 2, 2026
TownePlace Suites by Marriott San Antonio Northwest
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top South Texas Medical Center Hotel Reviews

San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

10/10 Excellent
"It was a great stay nothing to complain about. Liked the service, cleanliness."
Biswapratap 2-night trip
Posted 22 hours ago
San Antonio Marriott Northwest Medical Center

Hotels near other South Texas Medical Center attractions

Cinemark San Antonio 16

You can take time to visit Cinemark San Antonio 16 during your travels to San Antonio.
See properties

USAA Corporate Office Headquarters

USAA Corporate Office Headquarters is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Stroll along the riverfront or attend a sporting event in this family-friendly area.
See properties

Frequently asked questions

What's the area like around South Texas Medical Center?
South Texas Medical Center is located in a walkable area of San Antonio known for its beautiful river views and biking. If you're looking for a convenient place to stay, check out the 40 hotels and other accommodations you'll find within a mile.
What's the best place to stay close to South Texas Medical Center?
Fairfield Inn & Suites by Marriott San Antonio Medical Center is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located just a short 0.6 mi (1 km) from South Texas Medical Center. Other good options close by include Park Inn by Radisson and Courtyard by Marriott Medical Center San Antonio.
How many hotels will I find close to South Texas Medical Center?
Expedia has 40 hotels and other accommodations within a mile from South Texas Medical Center.
If I need to cancel the hotel reservation for my stay near South Texas Medical Center, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within 24 hours of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to view the best options available near South Texas Medical Center.
What can I see and do near South Texas Medical Center?
You can enjoy live performances at Woodlawn Theater and Sheldon Vexler Theatre. Create some family memories at Crystal Ice Palace and Monster Mini Golf. Looking for a little shopping break? A trip to Huebner Oaks, Ingram Park Mall, and Wonderland of the Americas Mall might be just the ticket while you're in the area around South Texas Medical Center.