OYO Inn & Suites Medical Center San Antonio

Property class: 2

Choose dates to view prices

Located close to Wonderland of the Americas Mall and South Texas Medical Center, OYO Inn & Suites Medical Center San Antonio has plenty to offer. Guests can connect to free WiFi in public areas.

Reviews

7.4 out of 10
Good

Popular amenities

  • Parking included
  • Air conditioning
  • Room service
  • Housekeeping
  • 24/7 front desk

Room options

Available filters for rooms
Showing 4 of 4 rooms

View all photos for Room, 2 Queen Beds

A hotel room with two beds, a television, and a window with a view of the outside.

Room, 2 Queen Beds

  • 22 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 1 King Bed

A hotel room with a large bed, a desk with a microwave, a window with a view of the street, and a door.

Room, 1 King Bed

9.4 out of 10
Exceptional
(14 reviews)
  • 22 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Premium Room, 1 King Bed

A hotel room with a bed, a nightstand, a desk, a TV, and a window with a view of trees.

Premium Room, 1 King Bed

  • 21 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 1 King Bed, Smoking

A hotel room with a large bed, two bedside lamps, a small table with chairs, and a framed picture on the wall.

Room, 1 King Bed, Smoking

7.0 out of 10
Good
(2 reviews)
  • 20 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

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About the neighborhood

Located in Medical Center District, a neighborhood in San Antonio, OYO Inn & Suites Medical Center San Antonio is in the entertainment district and near the airport. Wonderland of the Americas Mall is worth checking out if shopping is on the agenda, while those wishing to experience the area's popular attractions can visit San Antonio Zoo and Aquarium and San Antonio Botanical Gardens. Don't miss out on a visit to Six Flags Fiesta Texas. Visit our San Antonio travel guide
View more Motels in San Antonio
Map
3782 NW Loop 410, San Antonio, TX, 78229

What's nearby

  • A river with a stone bridge, trees with colorful lights, and a restaurant with flags.
    River Walk
    11 min drive - 15.4 km
  • An amusement park with roller coasters, a Ferris wheel, and various rides.
    Six Flags Fiesta Texas
    13 min drive - 18.8 km
  • Wonderland of the Americas Mall
    7 min walk - 0.6 km
  • First Unitarian Universalist Church
    1 min drive - 1.9 km
  • Oak Hills Country Club
    4 min drive - 1.9 km

Getting around

  • San Antonio Station
    17 min drive
  • Victoria, TX (VCT-Victoria Regional)
    156 min drive

Restaurants

  • QuikTrip
    7 min walk
  • Chick-fil-A
    11 min walk
  • Goomba's Pizzeria
    7 min walk
  • Whataburger
    10 min walk
  • Dave & Buster's
    13 min walk

About this property

OYO Inn & Suites Medical Center San Antonio

  • Motel near South Texas Medical Center
  • Located close to Wonderland of the Americas Mall and San Antonio Zoo and Aquarium, OYO Inn & Suites Medical Center San Antonio has plenty to offer. Guests can connect to free WiFi in public areas.
  • You'll also enjoy the following perks during your stay:
    • Free self parking
    • A vending machine and a 24-hour front desk
  • Room features
  • All guestrooms at OYO Inn & Suites Medical Center San Antonio boast comforts such as air conditioning, as well as amenities like high-speed internet.
  • Other conveniences in all rooms include:
    • Bathrooms with showers and free toiletries
    • 32-inch flat-screen TVs with cable channels
    • Mini fridges, microwaves, and daily housekeeping

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Frequently asked questions

Is OYO Inn & Suites Medical Center San Antonio pet-friendly?

No, only service animals are welcome at the property.

How much is parking?

Self parking is free at this property.

What time is check-in at OYO Inn & Suites Medical Center San Antonio?

Check-in begins at 3:00 PM. A fee applies for early check-in (subject to availability).

What time is check-out at OYO Inn & Suites Medical Center San Antonio?

Check-out is at 11 AM. Late check-out is available for a fee (subject to availability).

Where is OYO Inn & Suites Medical Center San Antonio located?

Located in Medical Center District, this motel is 0.3 mi (0.5 km) from Wonderland of the Americas Mall and 2.7 mi (4.4 km) from South Texas Medical Center. San Antonio Zoo and Aquarium and River Walk are also within 9 mi (15 km).

Can I cancel my reservation for free and receive a full refund?

Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.

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Reviews

OYO Inn & Suites Medical Center San Antonio Reviews

7.4

Good

7.2

Cleanliness

7.4

Location

7.8

Staff & service

6.8

Property conditions & facilities
Rating 10 - Excellent. 101 out of 251 reviews
Rating 8 - Good. 54 out of 251 reviews
Rating 6 - Okay. 31 out of 251 reviews
Rating 4 - Poor. 26 out of 251 reviews
Rating 2 - Terrible. 39 out of 251 reviews

Reviews

Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It was quiet and clean and the staff was very friendly
Stayed 1 night in May 2026
Verified review

8/10 Good

Liked: Cleanliness, staff & service, property conditions & facilities
Staff was courteous and professional and the room is nice.
Stayed 1 night in Dec 2025
Verified review

8/10 Good

Liked: Cleanliness, amenities, property conditions & facilities
The staff was courteous, and professional and the room was very good.
Stayed 2 nights in Dec 2025
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities
Excellent property!! Staff were very kind.
Stayed 1 night in Aug 2025
Verified review

10/10 Excellent

Liked: Cleanliness, amenities, property conditions & facilities
Staff was friendly and helpful, with no issues checking-in.
Stayed 1 night in Oct 2025
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Quiet area
Stayed 7 nights in Apr 2025
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, property conditions & facilities
Safe quite easily accessible
Stayed 1 night in Oct 2023
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, property conditions & facilities
Quite and comfortable
Stayed 1 night in Oct 2023
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
My husband and son had a great stay it was close to the UT HOSPITAL so it was great for my family to come see me during my stay. The floor was a little dingy but it's expected with an older hotel.
Stayed 2 nights in Nov 2023
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
It was comfortable
Stayed 1 night in Oct 2024
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The gentleman at front was pleasant, caring, friendly. Rooms clean! Great experience will return when in area
Stayed 1 night in Sep 2023
Verified review

6/10 Okay

Ok. The manager seemed understated, quiet, easy going. When he ran my card tho, he listed hotel as Country Hearth or some such and my card auto declined having nothing to do with me. Used my debit card. Area appeared safe off 410. Room was so so. Holes in bedspread, holes in curtain. Cracks in granite sink. My drink froze in fridge overnite.teied to thaw in microwave, but then it was too watery. Tub had what appeared to be cigarette burns on edge. But major problem was that the towels and washcloths were dingy and not fluffy. Past Time to replace these!!
Verified review

6/10 Okay

Liked: Staff & service
Disliked: Property conditions & facilities
Here is the positive before the negative. I give 3 out of 5 stars due to: 1. The staff was friendly 2. Was a quick check-in 3. The water was hot 4. The bed & pillows were comfort 5. TV, fridge, microwave worked 6. Ice maker worked. Negative was the towels had stains on them,we had to ask for clean ones. The shower curtain had stains on them as well. The toilet seat was not secure. Needed fixing. The grounds need cleaning, the doors have pealing paint as well the rest of the building and stairs need paint. The cost per room was very cheap so I guess you get what you pay for. If your staying a night in San Antonio and on a budget, this place would be fine for you. Next time for me I will pay more for more cleanliness elsewhere.
Stayed 2 nights in Mar 2024
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
great place to stay close to the hospital. Would stay there again
Stayed 1 night in Jun 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very clean, respectful staff hotel room was very beautiful cleaned most definitely will be returning
Stayed 1 night in Apr 2026
Verified review

6/10 Okay

Good
Stayed 2 nights in Aug 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Always great stay
Stayed 1 night in Jul 2025
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Beautiful place to stay love it
Stayed 1 night in Feb 2025
Verified review

10/10 Excellent

Liked: Staff & service, amenities, property conditions & facilities
Nice place to stay lovely
Stayed 1 night in Feb 2025
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
It was a wonderful stay.
Stayed 1 night in Jan 2023
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This is a beautiful place to stay lovely 😍
Stayed 1 night in Feb 2025
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This is a beautiful place to stay ❀️ πŸ’–
Stayed 1 night in Mar 2025
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Was good last minute trip thanks
Stayed 1 night in Jun 2025
Verified review

10/10 Excellent

Liked: Cleanliness
Was a great little place
Stayed 1 night in Oct 2024
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
The location is great the staff were very nice the room was very agreeable thanks
Stayed 1 night in Aug 2025