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Santee Trips (flight + hotel)
Plan, book, travel with confidence
Better together
Save up to P 3,500 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Top hotels in Santee
![Lewis and Clark Resort](https://images.trvl-media.com/lodging/12000000/11270000/11268000/11267995/58d56b10_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Lewis and Clark Resort
43496 Shore Drive, Yankton, SD
8.6/10 Excellent! (165 reviews)
"Old fashioned"
Reviewed on May 25, 2024
![Spacious, Scenic Wagner Haven w/ River Access](https://images.trvl-media.com/lodging/95000000/94960000/94957500/94957470/cf86a64d_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Spacious, Scenic Wagner Haven w/ River Access
Wagner
![Crofton Cabin w/ Tiki Hut & Water Views!](https://images.trvl-media.com/lodging/94000000/93550000/93545800/93545783/a7bdad81_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Popular places to visit
Niobrara State Park
Take photos of the iconic old railroad bridge and camp in the cabins at the confluence of the Niobrara and Missouri rivers.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.