Santee Vacation Rentals

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Check prices for these dates

In two weeks
Dec 5 - Dec 7
In two months
Jan 16 - Jan 18
In three months
Feb 13 - Feb 15
In four months
Mar 13 - Mar 15

Vacation Rentals in Santee

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Top Santee Hotel Reviews

Lewis and Clark Resort

Lewis and Clark Resort

10/10 Excellent
"Beautiful view, easy check in, and spacious accommodations! We loved our stay and can’t wait to come back!"
Jessica 1-night trip
Posted 7 days ago
Lewis and Clark Resort

Find out more about Santee

Search for holiday rentals in Santee on Expedia! You can easily find your home rentals, villas, holiday apartments in Santee using one of the methods below:

  • View our selection of featured holiday rentals in Santee
  • Use the map to find apartments and other holiday homes in the Santee neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santee while they last

Look no further and take a look at our great range of rental properties in Santee!

Frequently asked questions

Can I find a vacation rental in Santee?

Yes, we give you a choice of vacation rentals near top points of interest in Santee, or you can select a more remote option if you'd like a relaxing place to stay.

What’s there to see and do in Santee?

While you're exploring the area, Lewis and Clark Lake and Lewis and Clark Recreation Area are a couple of picturesque spots to get outside and enjoy nature. Niobrara State Park and Lesterville Recreation Area are a couple of places you'll find in the larger area.

What’s a vacation rental in Santee like?

A vacation rental is a private property you can book for a few weeks or just a few days in Santee. Vacation rentals offer amenities like WiFi and washers and dryers so you'll have all the comforts of home. If you're concerned about a clean environment, a vacation rental can offer a sense of privacy away from public hotel elevators and busy front desks while still allowing you the enjoyment of travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a great choice for a family getaway.