Photo by Liza Buban-Tantuco
Business Hotels in Santa Mesa, Manila
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Santa Mesa Business Hotels
Our top choices for Santa Mesa business-friendly hotels
9.0 out of 10, Wonderful, (830)
"Great place to stay and closest to everything."
Sharon F
The price is P4,656
P5,250 total
includes taxes & fees
Dec 17 - Dec 18
8.4 out of 10, Very Good, (975)
"Clean room and friendly staff. "
Larry
The price is P2,288
P2,562 total
includes taxes & fees
Jan 2 - Jan 3, 2026
8.2 out of 10, Very Good, (2510)
"Great location "
Shaun
The price is P2,692
P3,150 total
includes taxes & fees
Dec 17 - Dec 18
8.2 out of 10, Very Good, (1003)
"Happy with the room and staff."
Muhammad Amer
The price is P3,275
P4,035 total
includes taxes & fees
Jan 15 - Jan 16, 2026
Holiday Inn Express Manila Newport City by IHG
Holiday Inn Express Manila Newport City by IHGNewport City
8.6 out of 10, Excellent, (1393)
"Excellent hotel, room, staff, facilities and breakfast."
Joseph
The price is P4,603
P5,616 total
includes taxes & fees
Jan 7 - Jan 8, 2026
8.4 out of 10, Very Good, (1003)
"Satisfied guest"
Edwin Leo
The price is P2,244
P2,513 total
includes taxes & fees
Dec 21 - Dec 22
8.8 out of 10, Excellent, (3253)
"Clean room and friendly staff. I had a great stay. "
Mark
The price is P3,867
P4,749 total
includes taxes & fees
Jan 2 - Jan 3, 2026
9.2 out of 10, Wonderful, (1638)
"Love this hotel, great location, staff are wonderful and it feels like home. "
Gavin
The price is P3,695
P4,138 total
includes taxes & fees
Dec 29 - Dec 30
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Santa Mesa Hotel Reviews
The Peninsula Manila
10/10 Excellent
Explore a world of travel with Expedia
Nearby Cities
More accommodations in Santa Mesa
- Condo Rentals in Manila
- Apartments in Manila
- Aparthotels in Manila
- Guest Houses in Manila
- Hostels in Manila
- Condo Resorts in Manila
- B&B in Manila
- Motels in Manila
- Residences in Manila
- Inns in Manila
- Vacation Homes in Manila
- Resorts in Manila
- Capsule Hotels in Manila
- Lodges in Manila
- RV Parks in Manila
- Pensions in Manila
Hotels near other Attractions
- Hotels near Doña Elena Tower
- Hotels near Polytechnic University of the Philippines
- Hotels near SM Mall of Asia
- Hotels near SM North EDSA
- Hotels near Newport World Resorts
- Hotels near U.S. Embassy
- Hotels near Venice Grand Canal Mall
- Hotels near Fort Bonifacio
- Hotels near Manila Ocean Park
- Hotels near City of Dreams Manila
Most Popular Hotels in Santa Mesa
- Seda BGC (Bonifacio Global City)
- Kabayan Hotel
- Conrad Manila
- City Garden Hotel Makati
- Hotel 101 - Manila
- Hilton Manila Newport World Resorts
- Ascott Makati
- Holiday Inn Express Manila Newport City by IHG
- Fairmont Makati
- Coro Hotel
- Sheraton Manila Hotel at Newport World Resorts
- TRYP by Wyndham Mall of Asia Manila
- Solaire Resort Entertainment City
- Shangri-La The Fort, Manila
- Red Planet Manila Binondo
- I’M Hotel
- Hyatt Regency Manila, City of Dreams
- Manila Marriott Hotel at Newport World Resorts
- The Sphere Serviced Residences Managed by HII
- Seda Residences Makati