Santa María Vacation Rentals

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
Jan 23 - Jan 25
In two months
Mar 6 - Mar 8
In three months
Apr 3 - Apr 5
In four months
May 1 - May 3

Our top choices for Santa María vacation rentals

Outdoor pool
Oceani Towers 1006

Oceani Towers 1006

Oceani Towers 1006
2.5 star property
La Boquilla
10.0 out of 10, Exceptional, (1)
"Todo estaba muy limpio, muy cómodo y el personal del edificio demasiado amigable."
United States
Nicolas Morantes
The price is P5,706
P5,706 total
Jan 11 - Jan 12
Oceani Towers 1006
Garden
Cabaña De Descanso, Isla De Barú - Cartagena - Rest Cabin, Baru Island -bolivar

Cabaña De Descanso, Isla De Barú - Cartagena - Rest Cabin, Baru Island -bolivar

Cabaña De Descanso, Isla De Barú - Cartagena - Rest Cabin, Baru Island -bolivar
2.0 star property
Cartagena
The price is P4,119
P4,119 total
Jan 12 - Jan 13
Cabaña De Descanso, Isla De Barú - Cartagena - Rest Cabin, Baru Island -bolivar
Outdoor pool
Apartamento premium en Baia Kristal

Apartamento premium en Baia Kristal

Apartamento premium en Baia Kristal
2.0 star property
Zona Norte
The price is P7,463
P8,737 total
Jan 19 - Jan 20
Apartamento premium en Baia Kristal
Terrace/patio
EcoHotel Hector

EcoHotel Hector

EcoHotel Hector
2.0 star property
Cartagena
10.0 out of 10, Exceptional, (4)
"Sin duda la mejor cabaña, la atenciòn excelente"
Colombia
Belkis
The price is P3,566
P3,566 total
Jan 15 - Jan 16
EcoHotel Hector
2 outdoor pools
Palmetto Resort BeachView

Palmetto Resort BeachView

Palmetto Resort BeachView
3.0 star property
Bocagrande
The price is P4,755
P14,266 total
Feb 7 - Feb 8
Palmetto Resort BeachView
43-inch Smart TV with digital channels, Netflix, streaming services
Bondo Estudio

Bondo Estudio

Bondo Estudio
3.5 star property
Marbella
9.2 out of 10, Wonderful, (640)
"Great Staff, and clean room."
United States
Michael
Bondo Estudio
Iron/ironing board, free WiFi
by Calamari Homes - Altamar Building

by Calamari Homes - Altamar Building

by Calamari Homes - Altamar Building
3.0 star property
Marbella
10.0 out of 10, Exceptional, (2)
"Great with room with ocean view and city view from the hallway."
United States
Ruth
The price is P9,192
P11,582 total
Jan 12 - Jan 13
by Calamari Homes - Altamar Building
Living area
Soy Local Centro Historico

Soy Local Centro Historico

Soy Local Centro Historico
3.0 star property
Cartagena Walled City
8.8 out of 10, Excellent, (136)
"Nice hotel that is very close to everything and accommodating"
United States
Jerron
Soy Local Centro Historico
3 outdoor pools
Premium Cartagena

Premium Cartagena

Premium Cartagena
3.0 star property
Bocagrande
The price is P7,809
P8,207 total
Jan 12 - Jan 13
Premium Cartagena
Free WiFi
Playa Mar Beach

Playa Mar Beach

Playa Mar Beach
2.0 star property
Bocagrande
The price is P3,963
P11,888 total
Jan 9 - Jan 10
Playa Mar Beach
Exterior
SUNSET BEACH

SUNSET BEACH

SUNSET BEACH
2.5 star property
Cartagena
8.0 out of 10, Very Good, (14)
"Hotel and the beach were amazing. The staff was very helpful and nice. "
United States
Xiomara
SUNSET BEACH
Pool
1404 Suite Frente al Mar en Cartagena

1404 Suite Frente al Mar en Cartagena

1404 Suite Frente al Mar en Cartagena
2.0 star property
Marbella
The price is P3,804
P5,706 total
Feb 8 - Feb 9
1404 Suite Frente al Mar en Cartagena
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santa María Hotel Reviews

Estelar Cartagena de Indias Hotel

Estelar Cartagena de Indias Hotel

10/10 Excellent
"This is probably one of the best properties to vacation in Cartagena. The staff is very friendly and courteous. I honestly wish I could have stayed longer than a week with them."
Ricardo 5-night trip
Posted 3 days ago
Estelar Cartagena de Indias Hotel

Find out more about Santa María

Search for holiday rentals in Santa María on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa María using one of the methods below:

  • View our selection of featured holiday rentals in Santa María
  • Use the map to find apartments and other holiday homes in the Santa María neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santa María while they last

Look no further and take a look at our great range of rental properties in Santa María!

Frequently asked questions

Are there vacation rentals in Santa María?

Yes, we have vacation rentals near well known attractions in Santa María, or you can choose a secluded option if you're looking for relaxation.

What are some of the best vacation home rentals that Santa María has to offer?

Casa Cascabel by Soho: Located near Santa María, this vacation home rental is located in the historical district and has an outdoor pool, a rooftop terrace, and air-conditioning to put you at ease in your new surroundings.

What’s there to see and do in Santa María?

While exploring the area, visit family-friendly sights like Caribbean Naval Museum, or get outside and enjoy nature at Marbella Beach. Las Americas International Convention Center and La Boquilla Beach are a couple of places you'll find in the larger area.

What’s a vacation rental in Santa María like?

Vacation rentals are privately owned properties you can book for short or long periods in Santa María. Vacation rentals offer amenities like kitchens and laundry facilities so you'll feel just like you're staying in your own home. If you're concerned about a clean environment, a vacation rental can offer a sense of security away from public hotel elevators and busy front desks while still allowing you a great travel experience. You'll also find more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a great choice for family trips or small group gatherings.