Santa Cruz Vacation Rentals

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Check prices for these dates

Tonight
Jan 5 - Jan 6
Tomorrow
Jan 6 - Jan 7
This weekend
Jan 9 - Jan 11
Next weekend
Jan 16 - Jan 18

Our top choices for Santa Cruz vacation rentals

Private kitchen
Lofts by Verticca

Lofts by Verticca

Lofts by Verticca
3.5 star property
Ojo de Agua
8.2 out of 10, Very Good, (13)
"This was absolutely wonderful they were kind and friendly the loft was very clean and spacious only thing I didn’t like was the tv’s weren’t smart tv’s they only had local cable channels "
United States
Berline
The price is P4,189
P5,027 total
includes taxes & fees
Jan 6 - Jan 7
Lofts by Verticca
Business center
Downtown Treasure Place

Downtown Treasure Place

Downtown Treasure Place
2.5 star property
Downtown Mexico City
8.8 out of 10, Excellent, (744)
"Always been my go to when i visit mexico ciyy! everything is close by too! Staff was super helpful and very nice! "
United States
Guadalupe
The price is P1,811
P2,164 total
includes taxes & fees
Jan 6 - Jan 7
Downtown Treasure Place
Dining room
Capitalia Antara Polanco

Capitalia Antara Polanco

Capitalia Antara Polanco
4.5 star property
Polanco
9.2 out of 10, Wonderful, (191)
"Amazing stay and perfect location"
United Kingdom
mehul
Capitalia Antara Polanco
City view
UTOPIC Polanco by ULIV

UTOPIC Polanco by ULIV

UTOPIC Polanco by ULIV
4.5 star property
Miguel Hidalgo
9.0 out of 10, Wonderful, (763)
"Everything was great about this Hotel! We were close to things and easy access "
United States
Geovana
UTOPIC Polanco by ULIV
Exterior
Casa Chopo

Casa Chopo

Casa Chopo
3.5 star property
Downtown Mexico City
9.4 out of 10, Exceptional, (110)
"Gorgeous property. "
United States
Jeff
The price is P2,600
P3,107 total
includes taxes & fees
Jan 6 - Jan 7
Casa Chopo
Rooftop terrace
Capitalia Aristoteles Polanco

Capitalia Aristoteles Polanco

Capitalia Aristoteles Polanco
4.0 star property
Polanco
9.2 out of 10, Wonderful, (120)
"Great location and a nice apartment "
United States
Luis F
The price is P9,771
P11,676 total
includes taxes & fees
Feb 3 - Feb 4
Capitalia Aristoteles Polanco
Living area
Bright & sweet unit in middle Polanco

Bright & sweet unit in middle Polanco

Bright & sweet unit in middle Polanco
3.0 star property
Polanco
9.8 out of 10, Exceptional, (49)
"This was my most pleasant stay in CDMX"
Canada
Bahman
The price is P3,008
P5,066 total
includes taxes & fees
Jan 8 - Jan 9
Bright & sweet unit in middle Polanco
Hypo-allergenic bedding, in-room safe, individually decorated
Kukun Homero Polanco

Kukun Homero Polanco

Kukun Homero Polanco
4.0 star property
Polanco
9.4 out of 10, Exceptional, (225)
"Amazing room accommodations, happy with our stay. Great neighborhood and close to the heart of Mexico City. Would stay there again! "
United States
Mariah
The price is P5,962
P7,125 total
includes taxes & fees
Jan 6 - Jan 7
Kukun Homero Polanco
In-room safe, blackout drapes, free WiFi, bed sheets
Hotel Monaco

Hotel Monaco

Hotel Monaco
3.5 star property
Historic Center
8.0 out of 10, Very Good, (813)
"Hotel was nice and the staff was friendly "
United States
Fidencio
The price is P3,399
P4,061 total
includes taxes & fees
Jan 6 - Jan 7
Hotel Monaco
Living area
Santa Maria Apartments by VH

Santa Maria Apartments by VH

Santa Maria Apartments by VH
3.5 star property
Downtown Mexico City
6.6 out of 10, (20)
"Good place enough room comfy and good for the price ! "
Canada
Josue Ignacio
Santa Maria Apartments by VH
Terrace/patio
Capitalia Nuevo Polanco

Capitalia Nuevo Polanco

Capitalia Nuevo Polanco
4.0 star property
Miguel Hidalgo
9.2 out of 10, Wonderful, (38)
"Awesome place and really good costumer service. For sure I will be back there "
Canada
Kevin
The price is P4,532
P6,005 total
includes taxes & fees
Jan 7 - Jan 8
Capitalia Nuevo Polanco
City view
Kukun Sócrates Polanco

Kukun Sócrates Polanco

Kukun Sócrates Polanco
2.0 star property
Polanco
8.6 out of 10, Excellent, (152)
"Nice place and good location "
United States
ifeka
The price is P6,436
P7,691 total
includes taxes & fees
Jan 8 - Jan 9
Kukun Sócrates Polanco
Front of property - evening/night
Grand Polanco Residencial

Grand Polanco Residencial

Grand Polanco Residencial
4.0 star property
Polanco
9.4 out of 10, Exceptional, (583)
"Amazing staff , great area and nice amenities.."
United States
Ariana
Grand Polanco Residencial
Cribs/infant beds, free WiFi, bed sheets
Park Life Masaryk

Park Life Masaryk

Park Life Masaryk
3.0 star property
Polanco
9.0 out of 10, Wonderful, (517)
"Loved it will stay here again "
United States
Valerie
Park Life Masaryk
Terrace/patio
A08 SUPER CITY SUITES AT PLAZA ACEQUIA

A08 SUPER CITY SUITES AT PLAZA ACEQUIA

A08 SUPER CITY SUITES AT PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
10.0 out of 10, Exceptional, (3)
"Limpio y cómodo "
Mexico
Caleb
A08 SUPER CITY SUITES AT PLAZA ACEQUIA
Living area
Mar Mediterraneo

Mar Mediterraneo

Mar Mediterraneo
3.5 star property
Miguel Hidalgo
The price is P2,119
P3,415 total
includes taxes & fees
Jan 6 - Jan 7
Mar Mediterraneo
Terrace/patio
Cerca de ti Residencia

Cerca de ti Residencia

Cerca de ti Residencia
3.0 star property
Polanco
8.0 out of 10, Very Good, (92)
"Super clean place, bigger than I expected, great location"
United States
jesus angel
The price is P3,281
P3,921 total
includes taxes & fees
Jan 6 - Jan 7
Cerca de ti Residencia
Exterior
Moderna, Cómoda Suite Nube en Tepotzotlán centro

Moderna, Cómoda Suite Nube en Tepotzotlán centro

Moderna, Cómoda Suite Nube en Tepotzotlán centro
4.0 star property
Tepotzotlán
9.8 out of 10, Exceptional, (6)
"El lugar es maravilloso"
Mexico
Karen Lizeth
The price is P3,205
P3,847 total
includes taxes & fees
Jan 6 - Jan 7
Moderna, Cómoda Suite Nube en Tepotzotlán centro
Interior detail
Residence L'heritage Aristóteles 140 by Bluebay

Residence L'heritage Aristóteles 140 by Bluebay

Residence L'heritage Aristóteles 140 by Bluebay
3.5 star property
Polanco
7.4 out of 10, Good, (427)
"Excelente todo "
Mexico
Edith
The price is P3,329
P3,978 total
includes taxes & fees
Feb 1 - Feb 2
Residence L'heritage Aristóteles 140 by Bluebay
Exterior
Moderna, Comoda Suite Palma en Tepotzotlán centro

Moderna, Comoda Suite Palma en Tepotzotlán centro

Moderna, Comoda Suite Palma en Tepotzotlán centro
3.0 star property
Tepotzotlán
10.0 out of 10, Exceptional, (2)
"Excelente lugar "
Mexico
Teodoro
The price is P3,847
P4,616 total
includes taxes & fees
Jan 13 - Jan 14
Moderna, Comoda Suite Palma en Tepotzotlán centro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG

Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG

10/10 Excellent
"Clean room staff "
An 1-night trip
Posted 2 days ago
Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG

Find out more about Santa Cruz

Search for holiday rentals in Santa Cruz on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Cruz using one of the methods below:

  • View our selection of featured holiday rentals in Santa Cruz
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Look no further and take a look at our great range of rental properties in Santa Cruz!

Frequently asked questions

Are there vacation rentals in Santa Cruz?

Yes, you can find vacation rentals near popular points of interest in Santa Cruz, or you can go with a secluded option if you want a relaxing place to stay.

What’s there to see and do in Santa Cruz?

Explore the area and family-friendly sights such as Perimagico, or get out into nature at a spot like Hacienda La Concepcion. Temple of San Francisco Javier and National Museum of the Viceroyalty are a couple of places you'll find in the larger area.

What’s a vacation rental in Santa Cruz like?

Vacation rentals are private properties you can book for a long or short time in Santa Cruz. Vacation rentals feature extras such as patios, hot tubs, and fire pits so you'll feel just like you're at home. If you're concerned about a clean environment, vacation rentals can provide a sense of seclusion away from public hotel elevators and busy front desks while still allowing you the enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for family trips.