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Santa Cruz Vacation Rentals

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Check prices for these dates

In two weeks
Oct 30 - Nov 1
In two months
Dec 11 - Dec 13
In three months
Jan 8 - Jan 10
In four months
Feb 5 - Feb 7

Our top choices for Santa Cruz vacation rentals

A modern hotel corridor with a glass wall displaying multilingual greetings, a staircase, and a clean, tiled floor.

1. A30 Plaza Acequia Suite Black Plus

A30 Plaza Acequia Suite Black Plus
4.0 star property
Cuautitlán Izcalli
10.0 out of 10, Exceptional, (1 review)
"Todo un ambiente acogedor"
Mexico
GENER KEINER
The price is P4,153
P6,214 total
includes taxes & fees
Oct 18 - Oct 19
A30 Plaza Acequia Suite Black Plus
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

2. A08 SUPER CITY SUITES AT PLAZA ACEQUIA

A08 SUPER CITY SUITES AT PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
10.0 out of 10, Exceptional, (3 reviews)
"Limpio y cómodo "
Mexico
Caleb
The price is P3,552
P5,493 total
includes taxes & fees
Oct 16 - Oct 17
A08 SUPER CITY SUITES AT PLAZA ACEQUIA
A bedroom with a bed, wooden headboard, bedside tables, and built-in wardrobe.

3. Moderna, Comoda Suite Palma en Tepotzotlán centro

Moderna, Comoda Suite Palma en Tepotzotlán centro
3.0 star property
Tepotzotlán
10.0 out of 10, Exceptional, (3 reviews)
"Friendly host who was very helpful in recommending things to do and places to eat. Located just a few blocks from the historical district. On your way there, you'll pass wonderful restaurants, coffee shops, gyms, and convient stores. This place is in a great location and having garage parking was a real plus. Absolutely a beautiful room and very clean. I was very impressed and highly recommend staying here."
United States
Nathan
The price is P4,599
P5,519 total
includes taxes & fees
Nov 14 - Nov 15
Moderna, Comoda Suite Palma en Tepotzotlán centro
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

4. A10 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

A10 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
9.4 out of 10, Exceptional, (6 reviews)
"Muy buena experiencia, todo muy claro y es diferente a lo convencional, tal vez digan que por el precio serán instalaciones no muy agradables, pero en verdad hay sorpresas recomendado ampliamente, la persona encargada de cuidar es muy amable y atento!!! "
Mexico
Jorge
The price is P3,552
P5,493 total
includes taxes & fees
Nov 13 - Nov 14
A10 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
A modern hotel corridor with a glass wall displaying multilingual greetings, a staircase, and a clean, tiled floor.

5. A05 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

A05 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
10.0 out of 10, Exceptional, (2 reviews)
"Lo único que me disgusta es que no hay agua caliente )): Pero sin duda iré todos los 12 de cada mes "
Mexico
Jeik
The price is P3,552
P5,493 total
includes taxes & fees
Oct 16 - Oct 17
A05 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
A modern hotel corridor with a glass wall displaying multilingual greetings, a staircase, and a clean, tiled floor.

6. A04 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

A04 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
9.4 out of 10, Exceptional, (3 reviews)
"Buenas instalaciones y ubicación para mis desplazamientos"
Mexico
ANGEL
The price is P3,552
P5,493 total
includes taxes & fees
Oct 18 - Oct 19
A04 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

7. A25 Full Suite MiniDept at Plaza Acequia

A25 Full Suite MiniDept at Plaza Acequia
3.5 star property
Cuautitlan Izcalli
10.0 out of 10, Exceptional, (1 review)
The price is P3,279
P6,361 total
includes taxes & fees
Nov 13 - Nov 14
A25 Full Suite MiniDept at Plaza Acequia
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

8. A07 SUPER CITY SUITES AT PLAZA ACEQUIA

A07 SUPER CITY SUITES AT PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
10.0 out of 10, Exceptional, (2 reviews)
"Buen lugar tranquilo "
Mexico
Valeria
The price is P3,279
P3,934 total
includes taxes & fees
Nov 13 - Nov 14
A07 SUPER CITY SUITES AT PLAZA ACEQUIA
Balcony

9. S09 PREMIUM SUITE Full Service WiFi

S09 PREMIUM SUITE Full Service WiFi
4.0 star property
Ciudad López Mateos
9.6 out of 10, Exceptional, (4 reviews)
"Excelente"
United States
Yulissa Rubi
The price is P3,330
P5,226 total
includes taxes & fees
Oct 16 - Oct 17
S09 PREMIUM SUITE Full Service WiFi
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

10. A02 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

A02 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
The price is P3,199
P5,035 total
includes taxes & fees
Nov 13 - Nov 14
A02 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

11. A14 SUPER PREMIUM SUITE AT PLAZA ACEQUIA

A14 SUPER PREMIUM SUITE AT PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
9.4 out of 10, Exceptional, (8 reviews)
"Buena la estancia "
Mexico
Héctor
The price is P3,552
P5,493 total
includes taxes & fees
Nov 14 - Nov 15
A14 SUPER PREMIUM SUITE AT PLAZA ACEQUIA
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

12. A24 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

A24 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
The price is P3,279
P5,130 total
includes taxes & fees
Oct 16 - Oct 17
A24 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
A hotel entrance with a modern design, featuring a glass door and a sign with multilingual greetings.

13. A03 SUPER CITY SUITE AT PLAZA ACEQUIA

A03 SUPER CITY SUITE AT PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
The price is P3,279
P6,771 total
includes taxes & fees
Oct 16 - Oct 17
A03 SUPER CITY SUITE AT PLAZA ACEQUIA
A palm tree in front of a building with arched windows and a brick facade.

14. cabañas en arcos del sitio

cabañas en arcos del sitio
3.0 star property
Nicolás Romero
The price is P7,690
P11,074 total
includes taxes & fees
Nov 1 - Nov 2
cabañas en arcos del sitio
A modern hotel corridor with a glass wall displaying multilingual greetings, a staircase, and a clean, tiled floor.

15. A13 SUPER CITY SUITE PLAZA ACEQUIA

A13 SUPER CITY SUITE PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
10.0 out of 10, Exceptional, (1 review)
"Buen servicio "
Mexico
Ruben
The price is P3,552
P5,459 total
includes taxes & fees
Nov 13 - Nov 14
A13 SUPER CITY SUITE PLAZA ACEQUIA
A modern bedroom with a large bed, a nightstand, a desk, and a view through large windows.

16. S10 PREMIUM SUITE Full Service WiFi

S10 PREMIUM SUITE Full Service WiFi
4.0 star property
Ciudad López Mateos
8.0 out of 10, Very good, (1 review)
"Habitacion limpia"
Mexico
Yolanda Sandoval
The price is P3,330
P5,226 total
includes taxes & fees
Oct 19 - Oct 20
S10 PREMIUM SUITE Full Service WiFi
A balcony with a blue chair, a table with a book, a water bottle, and a potted plant.

17. S08 PREMIUM SUITE Full Service WiFi

S08 PREMIUM SUITE Full Service WiFi
4.0 star property
Ciudad López Mateos
The price is P3,059
P4,896 total
includes taxes & fees
Oct 17 - Oct 18
S08 PREMIUM SUITE Full Service WiFi
Living area

18. Lofts by Verticca San Francisco

Lofts by Verticca San Francisco
3.5 star property
Ojo de Agua
8.6 out of 10, Excellent, (45 reviews)
"Nice place! "
Canada
erick
The price is P3,578
P4,293 total
includes taxes & fees
Oct 21 - Oct 22
Lofts by Verticca San Francisco
A modern living room with a sofa, a glass coffee table, a dining table with chairs, a painting on the wall, and a ceiling light.

19. Lofts by Verticca Héroes

Lofts by Verticca Héroes
2.0 star property
Ojo de Agua
10.0 out of 10, Exceptional, (1 review)
The price is P3,922
P4,707 total
includes taxes & fees
Oct 16 - Oct 17
Lofts by Verticca Héroes
A spacious indoor area with a high ceiling, metal beams, and a staircase. There are multiple seating areas with tables and chairs, and a variety of plants are visible.

20. Downtown Treasure Place

Downtown Treasure Place
2.5 star property
Cuauhtémoc
8.8 out of 10, Excellent, (916 reviews)
"Very good place , clean and pleasant place, I like it too much and it has the best morning breakfast"
United States
demetrio quintana
The price is P1,849
P2,209 total
includes taxes & fees
Oct 16 - Oct 17
Downtown Treasure Place
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Holiday Inn Express Mexico Basilica by IHG

Holiday Inn Express Mexico Basilica by IHG

10/10 Excellent
"Everything was very good,!! However I would really appreciate a mini fridge in the room."
Laura 3-night trip
Posted 7 hours ago
Holiday Inn Express Mexico Basilica by IHG

Find out more about Santa Cruz

Search for holiday rentals in Santa Cruz on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Cruz using one of the methods below:

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Look no further and take a look at our great range of rental properties in Santa Cruz!

Frequently asked questions

Are there vacation rentals in Santa Cruz?

Yes, you can find vacation rentals near popular points of interest in Santa Cruz, or you can go with a secluded option if you want a relaxing place to stay.

What’s there to see and do in Santa Cruz?

Explore the area and family-friendly sights such as Parque Acuatico Vito Spa, or get out into nature at a spot like Hacienda La Concepcion. Temple of San Francisco Javier and National Museum of the Viceroyalty are a couple of places you'll find in the larger area.

What’s a vacation rental in Santa Cruz like?

Vacation rentals are private properties you can book for a long or short time in Santa Cruz. Vacation rentals feature extras such as patios, hot tubs, and fire pits so you'll feel just like you're at home. If you're concerned about a clean environment, vacation rentals can provide a sense of seclusion away from public hotel elevators and busy front desks while still allowing you the enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for family trips.