Santa Cruz Trips (flight + hotel)

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    Save up to P 3,118 when you book a flight and hotel together*
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Top hotels in Santa Cruz

InterContinental Presidente Mexico City by IHG
InterContinental Presidente Mexico City by IHG
4 out of 5
Campos Eliseos 218, Mexico City
Fully refundableReserve now, pay when you stay
The price is P11,287 per night from Jul 25 to Jul 26
P11,287
P13,488 total
Jul 25 - Jul 26
includes taxes & fees
9.2/10 Wonderful! (1,754 reviews)
"A 5 star hotel, with many amenities, restaurants and excellent service. Request a room overlooking the city."

Reviewed on Jun 27, 2025

InterContinental Presidente Mexico City by IHG
Casa Olea
Casa Olea
3 out of 5
C. de Francisco Díaz Covarrubias, 76, Mexico City, CDMX
Fully refundableReserve now, pay when you stay
The price is P4,021 per night from Jul 7 to Jul 8
P4,021
P4,805 total
Jul 7 - Jul 8
includes taxes & fees
9.2/10 Wonderful! (328 reviews)
"Very friendly stuff abd services Very clean 👌"

Reviewed on Jul 3, 2025

Casa Olea
Hyatt Regency Mexico City
Hyatt Regency Mexico City
5 out of 5
Campos Eliseos No. 204 Polanco, Chapultepec, Mexico City
The price is P9,028 per night from Jul 26 to Jul 27
P9,028
P10,789 total
Jul 26 - Jul 27
includes taxes & fees
9.2/10 Wonderful! (1,079 reviews)
"Great service, location and breakfast. Good gym and pool. Great value in my opinion."

Reviewed on Jun 11, 2025

Hyatt Regency Mexico City
See all 1,789 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Hacienda La Concepcion

You can take time to visit Hacienda La Concepcion during your travels to Tepotzotlán. Amble around the area's parks or experience its museums.

Hacienda La Concepcion

St. Peter the Apostle Church

Learn about the local history of Tepotzotlán when you take a trip to St. Peter the Apostle Church.

St. Peter the Apostle Church

La Concepción Dam

You can find out about the history of Tepotzotlán with a visit to La Concepción Dam. Amble around the area's parks or experience its museums.

La Concepción Dam

What to do in Santa Cruz

Xochimilco, Frida Kahlo Museum, Coyoacan & UNAM Tour

Xochimilco, Coyoacan, Frida Kahlo Museum (Optional Visit) & Art Murals

P2,753
per adult
84% of travellers recommend
Xochimilco, Coyoacan, Frida Kahlo Museum (Optional Visit) & Art Murals
ATV Adventure

Private Jeep & ATV Tour to Jade Cavern in Cozumel: All-Inclusive

P7,303
per adult
Private Jeep & ATV Tour to Jade Cavern in Cozumel: All-Inclusive
Steer route: Tour of the ruins and tasting in Mazatan

Steer route: Tour of the ruins and tasting in Mazatan

P9,880
per adult
Steer route: Tour of the ruins and tasting in Mazatan
See all activities in Santa Cruz

Frequently asked questions

How much does a Santa Cruz vacation package cost?
Offering excellent value package deals on Expedia, you'll be pleasantly surprised at how much a vacation to Santa Cruz costs! Our packages make travel planning easier and save you more.
What are the cheapest months to go to Santa Cruz?
You can usually find reduced prices and better availability in January, February and June. Explore our cheap Santa Cruz vacation packages and you could score some great off-season discounts.
How many days is enough for Santa Cruz?
The ideal duration for your Santa Cruz vacation depends on what you'd like to see. Typically, a few days to a week will give you time to hit all the top attractions and discover some hidden treasures along the way.
How to find the best Santa Cruz package deals?
Bagging a cheap Santa Cruz package deal is a breeze with Expedia. Once you've entered your destination and travel dates under our "Packages" tab, set your budget, add some filters and browse what's available. You can personalize your search by "Amenities," "Property type," "Popular locations" and more. Sort the results by "Price: low to high" to discover the most wallet-friendly Santa Cruz package deals. Want a simple trick to score even more savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are often lower.
Is it cheaper to book a Santa Cruz vacation as a package?
Expedia vacation packages are designed to help you keep more cash in your pocket. Bundle your car rental, hotel and flight into one great-value price and enjoy significant savings. You'll usually land a better deal than booking each component individually. And you'll still enjoy the freedom to create a customized Santa Cruz vacation by choosing your preferred accommodation type, airline and car class.
When to book a vacation package to Santa Cruz?
If you're planning a spontaneous Santa Cruz trip, browse our last-minute deals that can be booked up to a week before you go. Don't want to leave things to the last minute? You can land incredible deals on your flights and hotels by booking ahead.
How to plan a trip to Santa Cruz?

  1. Choose your dates: The things you want to do in Santa Cruz and your favorite season can help you decide when to go.
  2. Set a budget: Consider expenses such as flights, food and transportation when calculating how much to put aside for your trip to Santa Cruz. Then, pick a hotel that matches your budget, whether that's an economical stay or a swankier retreat.
  3. Decide your trip length: Consider how much time you want to spend exploring Santa Cruz. Plan your itinerary so you can get to all the attractions and activities you're interested in without rushing.
  4. Combine your accommodations and airfare: Once you've nailed down your travel dates and duration, book the ideal Santa Cruz vacation package for you.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.