Santa Cruz Hotels

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Nov 21 - Nov 22
Tomorrow
Nov 22 - Nov 23
This weekend
Nov 21 - Nov 23
Next weekend
Nov 28 - Nov 30

Filter by

Guest rating
Guest rating
Star rating

Top 10 trending Santa Cruz hotels

Exterior
Hotel Dos Rios

Hotel Dos Rios

3.0 star property
Nueva California
8.6 out of 10, Excellent, (71)
"Best food in town. Im serious! Beautiful geounds and great sports bar."
United States
Peter
Hotel Dos Rios
Property grounds
Little Italy B&B

Little Italy B&B

3.0 star property
Tijeras
9.4 out of 10, Exceptional, (49)
"Quiet and clean. Very nice stay!"
United States
patrick
The price is P2,357
P2,593 total
includes taxes & fees
Nov 29 - Nov 30
Little Italy B&B
Restaurant
Los Quetzales Ecolodge & Spa

Los Quetzales Ecolodge & Spa

3.0 star property
Cerro Punta
8.8 out of 10, Excellent, (32)
"Rustic gem in Cerro Punta. If you want to have a true small town experience yet have all the comforts, this is the place. The restaurant and the attached common guest space is the highlight. The staff is super friendly and make you truly feel at home. "
United States
Biren
Los Quetzales Ecolodge & Spa
Property entrance
Hotel Las Canarias

Hotel Las Canarias

3.0 star property
Paso Canoas
The price is P2,678
P2,946 total
includes taxes & fees
Nov 22 - Nov 23
Hotel Las Canarias
Exterior
Hotel Finca Lerida

Hotel Finca Lerida

3.0 star property
Los Naranjos
8.8 out of 10, Excellent, (184)
"The property is beautifully located on a coffee farm. The rooms are nice and bright. The restaurant is beautiful with outdoor seating with views of the mountain tops. The weather is prefect and you do not need an air conditioner. The staff were wonderful especially Luis. "
United States
Rene
Hotel Finca Lerida
Spa
Hotel Bambito By Faranda Boutique, a member of Radisson Individuals

Hotel Bambito By Faranda Boutique, a member of Radisson Individuals

3.0 star property
Volcan
8.2 out of 10, Very Good, (235)
"Great hotel"
United States
Alex
The price is P5,156
P5,672 total
includes taxes & fees
Nov 23 - Nov 24
Hotel Bambito By Faranda Boutique, a member of Radisson Individuals
Premium bedding, blackout drapes, iron/ironing board, free WiFi
Luxury Canyon Suites

Luxury Canyon Suites

2.0 star property
Alto Boquete
7.6 out of 10, Good, (4)
"New place, still developing "
United States
Amanda
The price is P8,498
P9,348 total
includes taxes & fees
Nov 22 - Nov 23
Luxury Canyon Suites
Exterior
Linda Vista Cabins

Linda Vista Cabins

3.0 star property
Alto Boquete
9.2 out of 10, Wonderful, (17)
"Property was the best local accommodation I have had in Panama. The host was outstanding. "
United States
Don
The price is P2,768
P3,045 total
includes taxes & fees
Nov 25 - Nov 26
Linda Vista Cabins
1 bedroom, premium bedding, down comforters, in-room safe
Los Brezos Boutique Hotel

Los Brezos Boutique Hotel

3.5 star property
Volcan
9.4 out of 10, Exceptional, (23)
"Los Brezos is the best hotel in the area. The restaurant is amazing, the food at all times is delicious and high standard"
United States
Damaris
Los Brezos Boutique Hotel
Hypo-allergenic bedding, individually decorated, individually furnished
Hostal Victoria Volcán Chiriquí S. A.

Hostal Victoria Volcán Chiriquí S. A.

2.0 star property
Nueva California
8.8 out of 10, Excellent, (8)
"Hostal Victoria was a simple and down-to-earth Hostal. The entire staff were friendly, kind, and helpful. Good value for a budget place to stay. "
United States
John
Hostal Victoria Volcán Chiriquí S. A.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santa Cruz Hotel Reviews

Hotel Dos Rios

Hotel Dos Rios

10/10 Excellent
"Best food in town. Im serious! Beautiful geounds and great sports bar."
Peter 3-night trip
Posted 2 months ago
Hotel Dos Rios
Luxury Canyon Suites

Luxury Canyon Suites

8/10 Good
"New place, still developing "
Amanda 1-night trip
Posted 9 months ago
Luxury Canyon Suites

More cheap stays in Santa Cruz

Luxury Canyon Suites

Luxury Canyon Suites

La Tranca Alto Boquete Provincia de Chiriquí
The price is P8,498 per night from Nov 22 to Nov 23
P8,498
P9,348 total
Nov 22 - Nov 23
includes taxes & fees
7.6/10 Good! (4 reviews)

Frequently asked questions

Where is the best place to stay in Santa Cruz?
Located 12.3 mi (19.8 km) from the heart of Santa Cruz, Hotel Bambito By Faranda Boutique, a member of Radisson Individuals is a top choice for your stay based on our traveler data. Two other choices for your trip to the area are Hotel Finca Lerida and Casa Grande Bambito Resort. See all available top hotels, or vacation rentals in Santa Cruz.
What are some of the best vacation home rentals in Santa Cruz?
Casa Little Italy: This vacation home rental outside of Santa Cruz offers a balcony, a terrace, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a garden. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! Most room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
What's it like to stay in Santa Cruz?
Visitors to Santa Cruz are sure to find plenty to explore and enjoy. There are 51 hotels and other accommodations in the surrounding area. Find out more about Santa Cruz.
What is there to see in Santa Cruz?
Places to visit in the wider area include Barriles, Área Silvestre Protegida Lagunas de Volcán, and Las Cavernas de Corredores. You'll also find Paradise Tropical Garden and Canyon Macho de Monte in the area. Check out what more to see and do in Expedia's Santa Cruz guide.
What's the weather like in Santa Cruz?
The hottest months are usually March and February with an average temp of 78°F, while the coldest months are January and December with an average of 77°F. The rainiest months in Santa Cruz are October, November, August, and July, with each month seeing an average of 30 inches of rainfall.

Explore a world of travel with Expedia