Santa Cruz Hotels

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Our top choices for Santa Cruz hotels

Linda Vista Cabins

Linda Vista Cabins
3.0 star property
Alto Boquete
9.2 out of 10, Wonderful, (18 reviews)
"Property was the best local accommodation I have had in Panama. The host was outstanding. "
United States
Don
The price is P2,952
P3,247 total
includes taxes & fees
May 4 - May 5
Linda Vista Cabins

Luxury Canyon Suites

Luxury Canyon Suites
2.0 star property
Alto Boquete
7.0 out of 10, Good, (6 reviews)
"New place, still developing "
United States
Amanda
The price is P5,352
P5,887 total
includes taxes & fees
Apr 27 - Apr 28
Luxury Canyon Suites

Hotel Finca Lerida

Hotel Finca Lerida
3.0 star property
Los Naranjos
8.8 out of 10, Excellent, (198 reviews)
"Great place"
United States
Roberto
The price is P11,759
P12,935 total
includes taxes & fees
May 1 - May 2
Hotel Finca Lerida

Los Quetzales Ecolodge & Spa

Los Quetzales Ecolodge & Spa
3.0 star property
Cerro Punta
8.8 out of 10, Excellent, (36 reviews)
"Staff were friendly and helpful. Room was okay."
Australia
Michael
The price is P6,439
P7,082 total
includes taxes & fees
Apr 23 - Apr 24
Los Quetzales Ecolodge & Spa

Little Italy B&B

Little Italy B&B
3.0 star property
Tijeras
9.4 out of 10, Exceptional, (52 reviews)
"Quiet and clean. Very nice stay!"
United States
patrick
The price is P2,395
P2,635 total
includes taxes & fees
Apr 29 - Apr 30
Little Italy B&B

Casa Little Italy

Casa Little Italy
3.0 star property
Tijeras
6.0 out of 10, (1 review)
"Didn't accept credit card payment "
Mexico
ANGELO
The price is P4,132
P4,545 total
includes taxes & fees
Apr 22 - Apr 23
Casa Little Italy

Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals

Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals
3.0 star property
Volcan
8.2 out of 10, Very Good, (253 reviews)
"nice classy place. with beautiful grounds.."
Canada
Gordon J
The price is P6,542
P7,196 total
includes taxes & fees
Apr 28 - Apr 29
Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals

Los Brezos Boutique Hotel

Los Brezos Boutique Hotel
3.5 star property
Volcan
9.4 out of 10, Exceptional, (30 reviews)
"Los Brezos is the best hotel in the area. The restaurant is amazing, the food at all times is delicious and high standard"
United States
Damaris
The price is P7,140
P7,854 total
includes taxes & fees
Apr 24 - Apr 25
Los Brezos Boutique Hotel

Hostal Victoria Volcán Chiriquí S. A.

Hostal Victoria Volcán Chiriquí S. A.
2.0 star property
Nueva California
9.0 out of 10, Wonderful, (10 reviews)
"Hostal Victoria was a simple and down-to-earth Hostal. The entire staff were friendly, kind, and helpful. Good value for a budget place to stay. "
United States
John
The price is P2,705
P2,975 total
includes taxes & fees
Apr 27 - Apr 28
Hostal Victoria Volcán Chiriquí S. A.

Hotel Dos Rios

Hotel Dos Rios
3.0 star property
Nueva California
8.6 out of 10, Excellent, (80 reviews)
"Beautiful garden "
Canada
Kevin
The price is P5,139
P5,653 total
includes taxes & fees
May 3 - May 4
Hotel Dos Rios

Hotel Las Canarias

Hotel Las Canarias
3.0 star property
Paso Canoas
The price is P2,732
P3,005 total
includes taxes & fees
Apr 18 - Apr 19
Hotel Las Canarias
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

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Frequently asked questions

Where is the best place to stay in Santa Cruz?
Located 12.3 mi (19.8 km) from the heart of Santa Cruz, Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals is a top choice for your stay based on our traveler data. Two other choices for your trip to the area are Hotel Finca Lerida and Los Quetzales Ecolodge & Spa. See all available top hotels, or vacation rentals in Santa Cruz.
What are some of the best vacation home rentals in Santa Cruz?
Casa Little Italy: This vacation home rental outside Santa Cruz offers a balcony, a terrace, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a garden. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! Most room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
What's it like to stay in Santa Cruz?
Visitors to Santa Cruz are sure to find plenty to explore and enjoy. There are 54 hotels and other accommodations in the surrounding area. Find out more about Santa Cruz.
What is there to see in Santa Cruz?
Places to visit in the wider area include Las Cavernas de Corredores, Barriles, and Paradise Tropical Garden. You'll also find Área Silvestre Protegida Lagunas de Volcán and Canyon Macho de Monte in the area. Check out what more to see and do in Expedia's Santa Cruz guide.
What's the weather like in Santa Cruz?
The hottest months are usually March and February with an average temp of 78°F, while the coldest months are January and December with an average of 77°F. The rainiest months in Santa Cruz are October, November, August, and July, with each month seeing an average of 30 inches of rainfall.