Santa Cruz Hotels

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Top 10 trending Santa Cruz hotels

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (342)
"Accommodating staff, comfortable rooms, wonderful pool"
Canada
Jay
The price is P7,736
P7,736 total
Dec 12 - Dec 13
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Ibis Santa Cruz DE LA Sierra

3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (69)
"Great Spot"
United States
Jose
The price is P2,083
P2,083 total
Dec 5 - Dec 6
Ibis Santa Cruz DE LA Sierra

Sun Hotel

3.5 star property
Santa Cruz
8.4 out of 10, Very Good, (327)
"Staff spoke English. Airport pickup beat any US hotel. Rooms nice. Restaurant was ok"
United States
Peter
The price is P5,294
P5,294 total
Nov 28 - Nov 29
Sun Hotel

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (253)
"Nice hotel "
United States
Narciso Lorenzo
The price is P3,771
P3,771 total
Nov 28 - Nov 29
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hotel Cortez

3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (120)
"The staff and property are second to none! "
United States
Cynthia
The price is P7,255
P7,255 total
Dec 5 - Dec 6
Hotel Cortez

Marriott Santa Cruz de la Sierra Hotel

5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (206)
"Great hotel, food and location albeit a little expensive "
United States
Reinaldo
The price is P6,553
P6,553 total
Dec 5 - Dec 6
Marriott Santa Cruz de la Sierra Hotel

Delfines Collection Hotel By Mercure

3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (71)
"Clean comfortable rooms "
United States
mary
The price is P2,745
P2,745 total
Nov 28 - Nov 29
Delfines Collection Hotel By Mercure

Camino Real Hotel

4.5 star property
Santa Cruz
8.8 out of 10, Excellent, (406)
"The parrots. Unique"
United States
Juan P
The price is P7,441
P7,441 total
Dec 10 - Dec 11
Camino Real Hotel

HOTEL OSHO

3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (28)
"Staff is great and place is comfortable "
United States
DITMAR
The price is P3,455
P3,455 total
Dec 21 - Dec 22
HOTEL OSHO

Apart Hotel Premium Suites Santa Cruz

3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (93)
"Come and go easily, intellectual and kind owners who are working hard to make the property improvements that will bring this hotel up to the next level. A family friendly environment with easy walking distance to everything you need. Bed was not the best, but I know they are upgrading so I appreciate the ongoing process. For a few nights stay, the deals are very fair prices. "
United States
Andrew
Apart Hotel Premium Suites Santa Cruz

Lido Hotel

3.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (29)
"Very helpful and nice staff. Quiet location. near the central plaza. Great value "
United Kingdom
David
The price is P2,705
P2,705 total
Nov 26 - Nov 27
Lido Hotel

Novotel Santa Cruz De La Sierra

5.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (103)
"Great location and very clean hotel. Will stay again soon."
United States
William
The price is P6,201
P6,201 total
Dec 5 - Dec 6
Novotel Santa Cruz De La Sierra

Hotel Las Américas

3.0 star property
Santa Cruz
6.0 out of 10, (1)
"O chuveiro foi impossível tomar um.banho de qualidade "
Brazil
Jean
The price is P2,269
P2,269 total
Nov 22 - Nov 23
Hotel Las Américas

TRYP by Wyndham Santa Cruz

4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (142)
"Nice stay with good service "
United States
Jianyuan
The price is P4,092
P4,092 total
Dec 1 - Dec 2
TRYP by Wyndham Santa Cruz

Hotel LP Santa Cruz Centro

3.0 star property
Santa Cruz
8.0 out of 10, Very Good, (280)
"Clean, friendly staff"
United States
Giovanna
Hotel LP Santa Cruz Centro

Chairú Eco Hotel

3.5 star property
Santa Cruz
9.6 out of 10, Exceptional, (44)
"Nice property. Would definitely stay there again and again. Only negative was on our last night there was a really noisy party next door that lasted until 2am. "
United States
Andrew
Chairú Eco Hotel

Premium Suites Deluxe Aparthotel Equipetrol

3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (78)
"Good price, great hotel!"
United States
James
The price is P2,303
P2,303 total
Nov 23 - Nov 24
Premium Suites Deluxe Aparthotel Equipetrol

Hotel G

3.5 star property
Santa Cruz
7.8 out of 10, Good, (104)
"Excelente Hotel "
Mexico
JACOB
Hotel G

Hotel LP Equipetrol

3.5 star property
Santa Cruz
8.2 out of 10, Very Good, (201)
"Nice place to stay"
United States
Ricardo
Hotel LP Equipetrol

Swissôtel Santa Cruz De La Sierra

4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (79)
"Beautiful hotel"
Australia
Joanna
The price is P6,118
P6,118 total
Dec 6 - Dec 7
Swissôtel Santa Cruz De La Sierra
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Showing deals for:Nov 28 - Nov 30
Save an average of 15% on thousands of hotels when you're signed in

Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most.

Hamacas

While Hamacas isn't home to many top sights, Santa Cruz Zoo and Las Brisas Shopping Center are some notable places to visit nearby.

Stay near popular Santa Cruz attractions

Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

San Lorenzo Cathedral showing a park

Top Santa Cruz Hotel Reviews

More cheap stays in Santa Cruz

Frequently asked questions

What's the best place for a stay in Santa Cruz?
Chairú Eco Hotel is a favorite with Expedia customers. This hotel offers 2 restaurants and a bar. Reviews from our site also recommend Alfonsina Hotel Boutique by Inboccaluppo and Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel as top options for your trip. See all available top hotels, or vacation rentals in Santa Cruz.
What's the top vacation rental that Santa Cruz has to offer?
Casa Vida: Visitors give good reviews to this Santa Cruz vacation home rental, which is located in a rural location and has an outdoor pool, a patio, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a full-sized fridge, a stovetop, and a microwave, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a private yard and a selection of games. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! Most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
What's the best budget-friendly accommodation in Santa Cruz?
Based on our traveler reviews, residencial francia - Hostel is a top choice for a less expensive stay. Other choices for your budget-friendly stay include Residencial Ikandire II and Nomad Hostel. View all budget hotels in Santa Cruz.
What's the best accommodation for a family trip to Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a hotel with an outdoor pool and a restaurant, and it's a top choice on Expedia for families. Other choices for your stay with the kids include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Camino Real Hotel. Attractions like Santa Cruz Zoo and Play Land Amusement Park are also fun for kids of all ages. Find more child-friendly accommodations in Santa Cruz.
What is the top LGBTQ-friendly accommodation in Santa Cruz?
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Swissôtel Santa Cruz De La Sierra and Radisson Hotel Santa Cruz are other good choices for your trip. See all available hotels listed as LGBTQ-friendly in Santa Cruz.
What's the best pet-friendly hotel in Santa Cruz?
Ibis Santa Cruz DE LA Sierra is a top hotel for people traveling with their pets, and offers a restaurant and free WiFi for its human guests. Other good options for you and your pet's trip include Hotel LP Equipetrol and Hotel LP Santa Cruz Centro. See more pet-friendly hotel accommodations in Santa Cruz.
What's the best luxury accommodation in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Camino Real Hotel and Novotel Santa Cruz De La Sierra are other upscale choices for your vacation. Find more luxury hotels in Santa Cruz.
What are some accommodations with pools in Santa Cruz?
Sun Hotel is a top hotel with a children's pool, an outdoor pool, and free buffet breakfast. A couple of other options that offer an onsite pool include Yotau All Suites Hotel and Buganvillas Hotel Suites & Spa. View all hotels with pools in Santa Cruz.
What is the best spa hotel in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a top luxury spa hotel featuring a rooftop terrace, a fitness center, tennis courts, and a bar. Spend an afternoon at Hotel Spa where you'll find massage treatments. Other popular spa hotels in Santa Cruz include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Camino Real Hotel. See all spa hotels in Santa Cruz.
How is it to stay in Santa Cruz?
Visitors to Santa Cruz are sure to enjoy the shopping. Tourists can also enjoy the city's cafes, zoo, and cathedral. In Santa Cruz, there are 274 hotels and other accommodations to choose from. Find out more about Santa Cruz.
What should I do while I'm visiting Santa Cruz?
Cultural venues include Ethno-folkloric Museum, Cine Center, and Sacred Art Museum. Landmarks like San Lorenzo Cathedral, Plaza 24 de Septiembre, and Blacutt Square might be worth a visit. Natural beauty is on display at Guembe Biocenter, Lomas de Arena Regional Park, and Arenal Park. Check out what more to see and do in Expedia's Santa Cruz guide.
How should I get around Santa Cruz?
To see more of the larger area, ride aboard one of the trains from Santa Cruz de la Sierra Station. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.
What's the weather like in Santa Cruz?
The hottest months are usually October and November with an average temp of 79°F, while the coldest months are June and July with an average of 70°F. Average annual precipitation for Santa Cruz is 48 inches.

Explore a world of travel with Expedia