Santa Clara Hotels

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Clara hotels

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
Tocumen
8.4 out of 10, Very Good, (1,833 reviews)
"This hotel is very clean and the Staff are very friendly."
United States
Doreen
The price is P6,750
P7,425 total
includes taxes & fees
Jun 10 - Jun 11
Riande Aeropuerto Hotel & Casino

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
San Antonio
9.0 out of 10, Wonderful, (1,008 reviews)
"Great service, very comfortable beds, truly excellent breakfast manager and staff. "
United States
Elizabeth
The price is P6,730
P7,403 total
includes taxes & fees
May 23 - May 24
Courtyard by Marriott Panama Metromall

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.2 out of 10, Wonderful, (291 reviews)
"Very good place to stay and safe place..!"
United States
Somnueg
The price is P7,408
P8,556 total
includes taxes & fees
May 21 - May 22
Arcadia Condo Suites

Panama Canal Inn

Panama Canal Inn
3.0 star property
Panama City
8.2 out of 10, Very Good, (21 reviews)
"Excellent hotel, good location, nice stay and great service."
United States
Rocio Hernandez
The price is P2,778
P3,673 total
includes taxes & fees
May 21 - May 22
Panama Canal Inn

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (694 reviews)
"Breakfast was exceptional, everything you could think of was available. The spa was great and the staff 10/10"
United States
Aeon
The price is P14,306
P15,737 total
includes taxes & fees
Jun 5 - Jun 6
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Beach House

The Beach House
3.0 star property
Amador
8.4 out of 10, Very Good, (432 reviews)
"Everting was clean and good nice place to stay "
United States
Kristine
The price is P4,592
P5,052 total
includes taxes & fees
May 21 - May 22
The Beach House

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
Bella Vista
8.8 out of 10, Excellent, (927 reviews)
"Great location and a decent breakfast for the price also the pool was nice."
United States
Mureen
The price is P3,611
P6,349 total
includes taxes & fees
May 21 - May 22
Waymore Hotel Spa & Casino

Serenade Lodging Rooms

Serenade Lodging Rooms
3.0 star property
San Francisco
8.4 out of 10, Very Good, (25 reviews)
"Nice affordable place. "
United States
Sandor
The price is P3,284
P3,613 total
includes taxes & fees
May 23 - May 24
Serenade Lodging Rooms

Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador
8.6 out of 10, Excellent, (1,023 reviews)
"Excellent location, good parking."
United States
Mark
The price is P5,571
P6,129 total
includes taxes & fees
Jun 4 - Jun 5
Radisson Hotel Panama Canal

MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel
3.5 star property
Amador
8.0 out of 10, Very Good, (253 reviews)
"The breakfast was good and lots of parking in a safe place "
United States
Tessa
The price is P4,792
P5,271 total
includes taxes & fees
May 24 - May 25
MARINN Tropical Vibes Hotel

The Executive Hotel

The Executive Hotel
3.5 star property
Bella Vista
9.2 out of 10, Wonderful, (1,115 reviews)
"It was a nice stay and breakfast is delicious"
United States
Susana
The price is P5,185
P5,704 total
includes taxes & fees
Jun 9 - Jun 10
The Executive Hotel

Renaissance Panama City Hotel

Renaissance Panama City Hotel
5.0 star property
Bella Vista
8.8 out of 10, Excellent, (216 reviews)
"Breakfast was very good, staff are very helpful and friendly "
United States
Farah
The price is P7,840
P8,624 total
includes taxes & fees
May 31 - Jun 1
Renaissance Panama City Hotel

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,002 reviews)
"The staff were excellent!"
United States
James
The price is P8,278
P9,106 total
includes taxes & fees
May 30 - May 31
Sheraton Grand Panama

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (5,460 reviews)
"Great food, excellent service, overall beautiful hotel."
United States
derinique
The price is P8,731
P9,604 total
includes taxes & fees
Jun 4 - Jun 5
Hotel Riu Plaza Panama

Albrook Inn

Albrook Inn
3.0 star property
Panama City
7.8 out of 10, Good, (607 reviews)
"great place. nature is amazing."
United States
Linda
The price is P3,940
P4,334 total
includes taxes & fees
May 22 - May 23
Albrook Inn

Hyatt Regency Panama City

Hyatt Regency Panama City
5.0 star property
Bella Vista
9.6 out of 10, Exceptional, (308 reviews)
"Loved the room, the restaurant and the Gym was very well equipped"
United States
Jennifer Irene
The price is P10,788
P11,866 total
includes taxes & fees
May 31 - Jun 1
Hyatt Regency Panama City

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,154 reviews)
"great breakfast, great staff"
United States
Eduardo
The price is P6,710
P7,381 total
includes taxes & fees
Jun 13 - Jun 14
Plaza Paitilla Inn Hotel

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.4 out of 10, Very Good, (1,530 reviews)
"Nice stay"
United States
Diego
Megapolis Hotel Panamá

Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals

Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals
2.5 star property
Calidonia
7.6 out of 10, Good, (282 reviews)
"The room was very clean and the staff is very friendly and help full breakfast was excellent perfect location ."
United States
Stacey
The price is P4,334
P4,767 total
includes taxes & fees
Jun 4 - Jun 5
Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,206 reviews)
"Clean room, very helpful staff and great breakfast."
United States
Emmanuela
The price is P6,402
P7,042 total
includes taxes & fees
Jun 3 - Jun 4
Ramada Plaza by Wyndham Panama Punta Pacifica
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Santa Clara attractions

Learn more about Santa Clara

Santa Clara awaits: its natural setting, monuments, history, and more!

Adobe

Top Santa Clara Hotel Reviews

More cheap stays in Santa Clara

Frequently asked questions

What's the best place for a stay in Santa Clara?
Located 15.8 mi (25.5 km) from the heart of Santa Clara, Hotel Riu Plaza Panama is a top choice for your stay based on our traveler data. Two other choices for your stay in the area are The Executive Hotel and Principe Hotel and Suites. See all available top hotels, or vacation rentals in Santa Clara.
If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable if cancelled before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Clara.
What is staying in Santa Clara like?
Visitors can enjoy all that Santa Clara has to offer including its monuments. A top sight in the area is Albrook Shopping Mall. There are 1730 hotels and other accommodations in the surrounding area. Find out more about Santa Clara.
What is there to see in Santa Clara?
A favorite place to visit is Culebra Cut. Additionally, you'll find Albrook Shopping Mall in the area. Check out what more to see and do in Expedia's Santa Clara guide.
What's the seasonal weather like in Santa Clara?
The hottest months are usually April and March with an average temp of 79°F, while the coldest months are January and February with an average of 78°F. The rainiest months in Santa Clara are July, August, November, and October, with each month seeing an average of 11 inches of rainfall.