Santa Clara Hotels

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Our top choices for Santa Clara hotels

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
Tocumen
8.6 out of 10, Excellent, (1,864 reviews)
"Very nice staff and confortable stay"
United States
MARIA
The price is P7,251
P7,976 total
includes taxes & fees
Mar 15 - Mar 16
Riande Aeropuerto Hotel & Casino

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (664 reviews)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is P15,624
P17,187 total
includes taxes & fees
Mar 7 - Mar 8
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (212 reviews)
"Really loved this place"
United States
Alejandra
The price is P4,805
P7,966 total
includes taxes & fees
Mar 19 - Mar 20
Arcadia Condo Suites

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
San Antonio
8.8 out of 10, Excellent, (1,003 reviews)
"Staff was good rooms clean just a good experience "
United States
Adrian
The price is P6,116
P6,728 total
includes taxes & fees
Mar 6 - Mar 7
Courtyard by Marriott Panama Metromall

Hyatt Regency Panama City

Hyatt Regency Panama City
4.5 star property
Bella Vista
9.8 out of 10, Exceptional, (198 reviews)
"Very clean modern rooms, spacious hotel, delicious breakfast, very friendly staff!"
Canada
Sheldon
The price is P9,531
P10,484 total
includes taxes & fees
Mar 7 - Mar 8
Hyatt Regency Panama City

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (4,963 reviews)
"Great pool and restaurant."
Canada
Terri
The price is P7,981
P8,779 total
includes taxes & fees
Mar 3 - Mar 4
Hotel Riu Plaza Panama

The Westin Panama

The Westin Panama
4.0 star property
Costa del Este
9.0 out of 10, Wonderful, (318 reviews)
"Great hotel and services"
United States
Pedro
The price is P15,919
P17,511 total
includes taxes & fees
Feb 21 - Feb 22
The Westin Panama

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,015 reviews)
"Good locatiion"
United States
Caren
The price is P7,349
P8,084 total
includes taxes & fees
Mar 8 - Mar 9
Sheraton Grand Panama

Renaissance Panama City Hotel

Renaissance Panama City Hotel
5.0 star property
Bella Vista
8.8 out of 10, Excellent, (152 reviews)
"Very good hotel, well located. "
United States
Andrés
The price is P7,349
P8,084 total
includes taxes & fees
Feb 21 - Feb 22
Renaissance Panama City Hotel

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
Bella Vista
9.0 out of 10, Wonderful, (713 reviews)
"Great place to stay and friendly staff!"
United States
Leonardo
The price is P4,581
P6,315 total
includes taxes & fees
Mar 17 - Mar 18
Waymore Hotel Spa & Casino

MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel
3.5 star property
Amador
8.2 out of 10, Very Good, (229 reviews)
"Great rooms, pleasant staff, lovely location, lots of eats and drinks options"
United States
Rajiv Sachin
The price is P4,021
P4,423 total
includes taxes & fees
Feb 18 - Feb 19
MARINN Tropical Vibes Hotel

The Beach House

The Beach House
3.0 star property
Amador
8.4 out of 10, Very Good, (414 reviews)
"We loved the staff, room & view! "
United States
Jerome
The Beach House

Hotel San Felipe

Hotel San Felipe
4.0 star property
Casco Viejo
9.4 out of 10, Exceptional, (299 reviews)
"Great staff and Hotel."
United States
Joshua
Hotel San Felipe

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,004 reviews)
"Beautiful hotel, great service. Breakfast buffet is amazing. "
United States
Tamara
The price is P16,770
P18,447 total
includes taxes & fees
Mar 9 - Mar 10
JW Marriott Panama

W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,006 reviews)
"Second time staying and it was flawless."
United States
Anthony
The price is P10,631
P11,694 total
includes taxes & fees
Mar 7 - Mar 8
W Panama

La Concordia Boutique Hotel

La Concordia Boutique Hotel
4.0 star property
Casco Viejo
9.6 out of 10, Exceptional, (205 reviews)
"Great staff. Awesome rooms. The rooftop bar was INCREDIBLE! Highly recommend. "
United States
Eric
La Concordia Boutique Hotel

Aloft Panama

Aloft Panama
3.5 star property
San Francisco
8.6 out of 10, Excellent, (956 reviews)
"Perfect stay for a few days at Panama!"
United States
Maria
The price is P6,511
P7,162 total
includes taxes & fees
Feb 22 - Feb 23
Aloft Panama

Hotel Bardot Boutique

Hotel Bardot Boutique
3.0 star property
Casco Viejo
9.0 out of 10, Wonderful, (8 reviews)
"What a special place! Very reasonable rate for an amazing location. 2 level suite was sweet! Love the decor. The staff and restuarant/bar is magnificent in every way!"
United States
Nicholas
The price is P11,866
P13,053 total
includes taxes & fees
Mar 17 - Mar 18
Hotel Bardot Boutique

Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador
8.6 out of 10, Excellent, (1,005 reviews)
"Unbeatable location if your visit is all about the Panama Canal. "
United States
Vitaliy
The price is P4,909
P5,400 total
includes taxes & fees
Mar 13 - Mar 14
Radisson Hotel Panama Canal

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,141 reviews)
"Hotel was very clean, the staff was very helpful and the breakfast was very good!"
United States
Monty
The price is P6,264
P6,891 total
includes taxes & fees
Feb 20 - Feb 21
Plaza Paitilla Inn Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's the best place for a stay in Santa Clara?
Located 15.8 mi (25.5 km) from the heart of Santa Clara, Hotel Riu Plaza Panama is a top choice for your stay based on our traveler data. Two other choices for your stay in the area are Hotel El Panama by Faranda Grand, a member of Radisson Individuals and W Panama. See all available top hotels, or vacation rentals in Santa Clara.
If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable if cancelled before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Clara.
What is staying in Santa Clara like?
Visitors can enjoy all that Santa Clara has to offer including its monuments. Top sights around the area include Albrook Shopping Mall and Multiplaza Pacific Mall. There are 1518 hotels and other accommodations in the surrounding area. Find out more about Santa Clara.
What is there to see in Santa Clara?
A favorite place to visit is Culebra Cut. Additionally, you'll find Albrook Shopping Mall and Multiplaza Pacific Mall in the area. Check out what more to see and do in Expedia's Santa Clara guide.
What's the seasonal weather like in Santa Clara?
The hottest months are usually April and March with an average temp of 79°F, while the coldest months are January and February with an average of 78°F. The rainiest months in Santa Clara are July, August, November, and October, with each month seeing an average of 11 inches of rainfall.