A beach with waves, a boat, and a forested hill in the background.

Santa Clara Vacation Rentals

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Check prices for these dates

In two weeks
Oct 9 - Oct 11
In two months
Nov 20 - Nov 22
In three months
Dec 18 - Dec 20
In four months
Jan 15 - Jan 17

Our top choices for Santa Clara vacation rentals

An outdoor seating area with a table and chairs, surrounded by potted plants and umbrellas, in front of a building with the sign 'SEVA NEGRA'.

1. La Palma Experience

La Palma Experience
3.0 star property
Amador
8.8 out of 10, Excellent, (12 reviews)
"I would recommend this hotel. It has a great location and offers a very pleasant experience."
United States
Juan Luis Perez
The price is P4,920
P5,412 total
includes taxes & fees
Sep 28 - Sep 29
La Palma Experience
A beach with rocky terrain and a distant building.

2. Habitación con entrada Privada en Playa Dorada + Kitchenette y baño.

Habitación con entrada Privada en Playa Dorada + Kitchenette y baño.
3.0 star property
Vacamonte
8.4 out of 10, Very good, (5 reviews)
"Really recommended! Omar is a superhost, very helpfull and lovely! Good facilities and there is a swimmingpool and a nice little beach."
United States
Cynthia
The price is P1,215
P1,870 total
includes taxes & fees
Sep 28 - Sep 29
Habitación con entrada Privada en Playa Dorada + Kitchenette y baño.
A modern outdoor swimming pool with a clear view of a tall building in the background.

3. Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
4.0 star property
San Francisco
8.6 out of 10, Excellent, (35 reviews)
"Modern and clean, including a pool and gym with stunning view. Staff were wonderful. Basic but good breakfast included. Better than a hotel."
United States
David
The price is P9,566
P10,523 total
includes taxes & fees
Sep 28 - Sep 29
Dovle Residences by HMS-Preferred Member
An outdoor seating area with tables and chairs, a view of the beach, and string lights.

4. Refugio Frente al Mar Vista Venao

Refugio Frente al Mar Vista Venao
3.0 star property
Veracruz
7.4 out of 10, Good, (3 reviews)
"The staff was very welcoming, the room was very clean and had all the commodities needed for a great experience! I highly recommend it and I'll definitely pay a second visit!"
United States
Victor
The price is P3,655
P4,020 total
includes taxes & fees
Sep 28 - Sep 29
Refugio Frente al Mar Vista Venao
A spacious indoor courtyard with tiled flooring, multiple seating areas, and hanging plants.

5. La Isabela Suites

La Isabela Suites
3.5 star property
Casco Viejo
10.0 out of 10, Exceptional, (212 reviews)
"Location in old town, across from Plaza Simon Bolivar, is the perfect place to venture around old town and the new city. Great restaurants and shops within easy walking distance. I relied on recommendations from the staff for a couple of things and their selections exceeded my expectations. Highly recommend staying if visiting Panama City."
United States
David
The price is P9,840
P10,824 total
includes taxes & fees
Sep 28 - Sep 29
La Isabela Suites
A rooftop pool with a city view, lounge chairs, and a clear sky.

6. Corporate Stays Arcadia | Executive Furnished Apartments

Corporate Stays Arcadia | Executive Furnished Apartments
4.0 star property
Costa del Este
9.2 out of 10, Wonderful, (385 reviews)
"Nice place good location"
United States
Rame
The price is P6,481
P10,428 total
includes taxes & fees
Oct 3 - Oct 4
Corporate Stays Arcadia | Executive Furnished Apartments
A multi-story building with balconies, large windows, and a clear blue sky.

7. Las Clementinas

Las Clementinas
3.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (203 reviews)
"Great food and location"
United States
James
The price is P9,479
P11,676 total
includes taxes & fees
Oct 13 - Oct 14
Las Clementinas
A modern hotel entrance with a well-lit facade, a prominent sign, and a landscaped garden area.

8. Yoo Panamá by Boutique Apartments

Yoo Panamá by Boutique Apartments
3.5 star property
Bella Vista
8.2 out of 10, Very good, (135 reviews)
"Great location and very nice hotel. Great pool and restaurants."
Canada
Howard
The price is P3,139
P12,137 total
includes taxes & fees
Sep 28 - Sep 29
Yoo Panamá by Boutique Apartments
A modern hotel lobby with a marble staircase, seating areas, and a large mirror reflecting the space.

9. Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (582 reviews)
"Always my choice when staying in Panama City. Great location for a great hotel. Clean, comfortable and a great value."
United States
Fredrick
The price is P5,779
P6,357 total
includes taxes & fees
Sep 28 - Sep 29
Torres de Alba Hotel & Suites

10. San Francisco by Wynwood House

San Francisco by Wynwood House
3.0 star property
San Francisco
9.2 out of 10, Wonderful, (63 reviews)
"Wonderful location. The staff is very friendly. I highly recommend a Coffee Shop right at the entrance: "La Vasquita"."
United States
Georg
The price is P6,464
P8,828 total
includes taxes & fees
Sep 28 - Sep 29
San Francisco by Wynwood House
A rooftop pool with lounge chairs and a bar, overlooking a city skyline at dusk.

11. Yoo Panama Luxury Ocean View Apartment

Yoo Panama Luxury Ocean View Apartment
3.5 star property
Bella Vista
8.4 out of 10, Very good, (6 reviews)
"Good price for the location."
United States
Mark
The price is P7,743
P8,517 total
includes taxes & fees
Oct 15 - Oct 16
Yoo Panama Luxury Ocean View Apartment
A rooftop pool area with lounge chairs and a table, overlooking a cityscape with tall buildings.

12. Boutique Apartments Panama

Boutique Apartments Panama
3.5 star property
Bella Vista
8.0 out of 10, Very good, (374 reviews)
"Great stay!!!!"
United States
fitz
The price is P2,706
P9,812 total
includes taxes & fees
Sep 28 - Sep 29
Boutique Apartments Panama
A modern living room with a sofa, a TV, a small table, and a balcony with a view of the city.

13. Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
9.0 out of 10, Wonderful, (2 reviews)
"Perfect"
United States
Lorenz
The price is P2,648
P12,474 total
includes taxes & fees
Sep 30 - Oct 1
Living 73 Panamá by Boutique Apartments
A modern living room with a sofa, armchair, dining table, and kitchen area with a TV and appliances.

14. Modern Apartments at The Gray Prime Location

Modern Apartments at The Gray Prime Location
4.0 star property
Bella Vista
8.6 out of 10, Excellent, (16 reviews)
"I love the place and it was in walking distance to many places if you want a uber"
United States
Denise
The price is P5,112
P5,623 total
includes taxes & fees
Sep 28 - Sep 29
Modern Apartments at The Gray Prime Location

15. Cozy La Chorrera Villa With Private Patio & Nature Views

Cozy La Chorrera Villa With Private Patio & Nature Views
2.0 star property
La Chorrera
The price is P3,083
P3,391 total
includes taxes & fees
Sep 28 - Sep 29
Cozy La Chorrera Villa With Private Patio & Nature Views
A high-rise hotel with a modern design, featuring a prominent entrance and multiple balconies.

16. Modern Apartments at the Hub City views

Modern Apartments at the Hub City views
3.0 star property
San Francisco
10.0 out of 10, Exceptional, (1 review)
The price is P7,361
P8,097 total
includes taxes & fees
Sep 28 - Sep 29
Modern Apartments at the Hub City views
A modern building with a sign reading "LA RESIDENCE" and a car parked in front.

17. La Résidence Panamá

La Résidence Panamá
3.5 star property
Bella Vista
9.2 out of 10, Wonderful, (21 reviews)
"Excellent rooms and fantastic staff!"
United States
Mohamad
The price is P8,097
P8,906 total
includes taxes & fees
Sep 30 - Oct 1
La Résidence Panamá
A rooftop pool area with lounge chairs and tables, surrounded by a city skyline at dusk.

18. Yoo Apartamento

Yoo Apartamento
3.0 star property
Bella Vista
9.4 out of 10, Exceptional, (26 reviews)
"Clean, easy access to everything, lovely view, well worth what it cost"
United States
Kevin
Yoo Apartamento
An outdoor seating area with tables and chairs, a tree with pink blossoms, and a cityscape view.

19. Modern Design Apartments near Sortis

Modern Design Apartments near Sortis
4.0 star property
Bella Vista
9.0 out of 10, Wonderful, (11 reviews)
"This property was much more than I expected, room and property was clean, lots of restaurants around the area, easy to get around, will certainly be back at this property"
United States
Kareem
The price is P3,933
P4,327 total
includes taxes & fees
Sep 29 - Sep 30
Modern Design Apartments near Sortis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Clara Hotel Reviews

Megapolis Hotel Panamá

Megapolis Hotel Panamá

10/10 Excellent
"loved my family suite !!! very spacious and cute ! awesome views… the pool was such a vibe even on the days it did rain the bar was still open. great location in the city"
Brittany 4-night trip
Posted 4 hours ago
Megapolis Hotel Panamá

Find out more about Santa Clara

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Look no further and take a look at our great range of rental properties in Santa Clara!

Frequently asked questions

Can I find vacation rentals in Santa Clara?

Yes, there are vacation rentals close to popular attractions in Santa Clara, or you can choose a secluded option if you'd like a relaxing place to stay. Santa Clara is known for its monuments.

What can I see and do in Santa Clara?

While exploring the area, visit family-friendly sights like Summit Botanical Gardens & Zoo, or get outside and enjoy nature at Culebra Cut. In the larger area, you’ll find Albrook Shopping Mall and Gamboa Rainforest Resort.

What are vacation rentals like in Santa Clara?

Vacation rentals are privately owned properties you can book for several days or longer in Santa Clara. Vacation rentals offer extras such as hot tubs, fire pits, and patios so you'll be comfy for your stay. If you're concerned about cleanliness, a vacation rental can offer a sense of seclusion away from shared hotel elevators and busy reception areas while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which makes a vacation rental an attractive choice for families.