Visit Otay Mesa West
Popular places to visit
San Diego Zoo
One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
San Diego Convention Center
During your trip, find out what's happening at San Diego Convention Center, a top convention center in San Diego. Experience the area's acclaimed art scene and entertainment choices.
SeaWorld
A fun family favourite, where you can get up close to the local marine life, enjoy fun rides and be wowed by the performances.
Balboa Park
One of America’s largest urban green spaces, Balboa Park is an exciting spot packed with art, culture, and a world-renowned zoo.
Petco Park
Purchase a hot dog and watch the San Diego Padres, California’s southernmost Major League Baseball team, play on their home field.
Things to do
San Diego Whale Watching & Dolphin Cruise
San Diego Old Town Trolley Hop-On Hop-Off Tour
San Diego Sunset Cruise from Mission Bay
San Diego Whale Watching Cruise
City Cruises San Diego: Premier Dinner Cruise
Haunted San Diego: The Only Ghost Tour with Exclusive Entry
Top hotels in Otay Mesa West
Hilton San Diego Mission Valley
After initially giving me a room that had not yet been cleaned, the second room was perfectly nice. Front desk staff was super friendly and helpful. Decent location, especially if you have a room facing away from the highway.
Reviewed on Nov 9, 2025
Hampton Inn & Suites by Hilton San Diego SeaWorld
From check-in to check-out everything was amazing. My children and I felt safe and comfortable. Staff was attentive and helpful. Rooms were clean and housekeeping was sweet, they organized my daughter's toys, thank you! Great breakfast selection, staff was very welcoming. Will be staying here in ...
Reviewed on Nov 6, 2025
Pendry San Diego
Clean rooms and friendly staff
Reviewed on Nov 8, 2025
Hard Rock Hotel San Diego
Great staff
Reviewed on Nov 9, 2025
Courtyard by Marriott San Diego Downtown Little Italy
Great stay and centrally located yet away from heavy foot taffic. Older building so parking structure is tight. Well appointed. Restaurant and bar is amazing. Must try. Friendly staff.
Reviewed on Nov 9, 2025
Legacy Resort Hotel & Spa
Nice
Reviewed on Nov 10, 2025
Other neighbourhoods around Otay Mesa West
Gaslamp Quarter
Fantastic nightlife and popular shops are a few of the things travelers enjoy most about Gaslamp Quarter. A visit to Gaslamp Museum at the Davis-Horton House or Harlem of the West Sites is also recommended, and you can jump aboard the metro at Gaslamp Quarter Station to get around town.
Downtown San Diego
Petco Park and Port of San Diego are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.
Little Italy
Little Italy is popular for its captivating waterfront views. Explore top sights like Maritime Museum of San Diego and San Diego Bay, and you can get around town on the metro at County Center - Little Italy Station.
North Park
North Park is well-liked for its restaurants. You can also take some time to explore sights in the surrounding area like San Diego Zoo and San Diego Natural History Museum.
Mid-City
If you're spending time in Mid-City, check out sights like Cal Coast Credit Union Open Air Theater or Viejas Arena and hop on the metro to see more the city at SDSU Transit Center Station or Alvarado Station.
Hillcrest
Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.
