Visit Otay Mesa West
Popular places to visit
San Diego Zoo
One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.
San Diego Convention Center
During your trip, find out what's happening at San Diego Convention Center, a top convention center in San Diego. Experience the area's acclaimed art scene and entertainment choices.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
SeaWorld
A fun family favourite, where you can get up close to the local marine life, enjoy fun rides and be wowed by the performances.
Balboa Park
One of America’s largest urban green spaces, Balboa Park is an exciting spot packed with art, culture, and a world-renowned zoo.
Port of San Diego
Explore the waterfront in San Diego with a trip to Port of San Diego. Wander the seaside and beautiful beaches in the area.
Things to do
San Diego Old Town Trolley Hop-On Hop-Off Tour
San Diego Whale Watching & Dolphin Cruise
Sunset Sail Along the San Diego Skyline
San Diego: 3 Hour Whale Watching Cruise
San Diego: Luggage Storage in Marina
City Cruises San Diego: Premier Dinner Cruise
Top hotels in Otay Mesa West
Sheraton San Diego Resort
We did not have a coffee maker in our room. We called and requested one. It was brought to our room fifteen minutes later. Once we figured out which outlet worked, we had coffee and tea on our balcony. Super! Perhaps you might check the electrical in room 554?
Reviewed on Dec 22, 2025
Bay Club Hotel & Marina
Very accommodating and friendly staff - at check-in, waiter staff and concierge Room was well kept. Spacious and comfortable, in a great location
Reviewed on Dec 21, 2025
The DEXTRO Little Italy, BW Premier Collection
would stay again and recommend
Reviewed on Dec 21, 2025
Courtyard by Marriott San Diego Downtown Little Italy
Cleanliness and staff were exceptional!
Reviewed on Dec 22, 2025
Legacy Resort Hotel & Spa
Overall- the staff, property and room were great
Reviewed on Dec 17, 2025
Hard Rock Hotel San Diego
Amazing hotel and staff. Easy check in process and clean room
Reviewed on Dec 21, 2025
Other neighbourhoods around Otay Mesa West
East Village
Travelers choose East Village for its lively bars. Hop aboard the metro at City College Trolley Station or Park and Market Trolley Station and check out top sights like Petco Park.
Gaslamp Quarter
Fantastic nightlife and popular shops are a few of the things travelers enjoy most about Gaslamp Quarter. A visit to Gaslamp Museum at the Davis-Horton House or Lyceum Theatre is also recommended, and you can jump aboard the metro at Gaslamp Quarter Station to get around town.
Downtown San Diego
Petco Park and Port of San Diego are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.
Marina District
Known for its fantastic nightlife and captivating waterfront views, there's plenty to explore in Marina District. Check out top attractions like Seaport Village and The Rady Shell at Jacobs Park, and jump on the metro at Seaport Village Station or Convention Center Station to see more of the city.
Little Italy
Little Italy is popular for its captivating waterfront views. Explore top sights like Maritime Museum of San Diego and San Diego Bay, and you can get around town on the metro at County Center - Little Italy Station.
North Park
North Park is well-liked for its restaurants. You can also take some time to explore sights in the surrounding area like San Diego Zoo and San Diego Natural History Museum.
