Otay Mesa West
San Diego
Visit Otay Mesa West
Popular places to visit
San Diego Zoo
One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.
San Diego Convention Center
During your trip, find out what's happening at San Diego Convention Center, a top convention center in San Diego. Experience the area's fascinating museums and acclaimed art scene.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
Petco Park
Purchase a hot dog and watch the San Diego Padres, California’s southernmost Major League Baseball team, play on their home field.
USS Midway Museum
A popular San Diego attraction where you can get on board the USS Midway and learn more about the realities of Navy life.
SeaWorld
A fun family favourite, where you can get up close to the local marine life, enjoy fun rides and be wowed by the performances.
Things to do
San Diego SEAL Tour by Land & Sea
USS Midway Museum with Direct-to-Gate
San Diego's City Harbor Sightseeing Cruise
Oceanside Whale and Dolphin Watching Adventures
Top hotels in Otay Mesa West
Hard Rock Hotel San Diego
Love it
Reviewed on May 8, 2026
The Sofia Hotel
Location
Reviewed on May 9, 2026
Paradise Point Resort & Spa
Room was cl
Reviewed on May 8, 2026
The DEXTRO Little Italy, BW Premier Collection
Great stay and friendly staff
Reviewed on May 9, 2026
Wyndham San Diego Bayside
Super close to cruise ports. Disney ship picks up right across the street
Reviewed on May 9, 2026
Best Western Seven Seas
The pool was great. The restaurant was the definition of fine, not great, not bad. The prices were pretty ridiculous. $5 for a tea or coffee is insane. Staff was attentive and responsive.
Reviewed on May 9, 2026
Other neighbourhoods around Otay Mesa West
Gaslamp Quarter
Fantastic nightlife and popular shops are a few of the things travelers enjoy most about Gaslamp Quarter. A visit to Gaslamp Museum at the Davis-Horton House or Lyceum Theatre is also recommended, and you can jump aboard the metro at Gaslamp Quarter Station to get around town.
Downtown San Diego
Petco Park and Port of San Diego are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.
Little Italy
Little Italy is popular for its captivating waterfront views. Explore top sights like Maritime Museum of San Diego and San Diego Bay, and you can get around town on the metro at County Center - Little Italy Station.
North Park
North Park is well-liked for its restaurants. You can also take some time to explore sights in the surrounding area like San Diego Zoo and San Diego Natural History Museum.
Hillcrest
Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.
Point Loma
The stunning beaches and island views are just a few highlights of Point Loma. Make a stop by Shelter Island or Humphreys Concerts by the Bay while you're exploring the area.
