Otay Mesa West

San Diego

A marina with boats docked, a city skyline with high-rise buildings, and a sunset with pink and orange clouds.

Things to do


Top hotels in Otay Mesa West

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
The price is P9,517 per night from Oct 25 to Oct 26
P9,517
P13,212 total
Oct 25 - Oct 26
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,356 reviews)
"Very nice place and location. However it is dated and needs to be upgraded."

Reviewed on Oct 5, 2026

Wyndham San Diego Bayside
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
The price is P12,985 per night from Oct 30 to Oct 31
P12,985
P18,236 total
Oct 30 - Oct 31
includes taxes & fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (2,916 reviews)
"Gorgeous location, dated facilities in places. Pricy for average rooms, 49 dollars a day to park and 3 bucks for a banana. Maybe comp me a banana with all that and my $8 coffee and I'd feel a bit better. Overall."

Reviewed on Oct 5, 2026

Paradise Point Resort & Spa
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
The price is P6,455 per night from Oct 6 to Oct 7
P6,455
P7,420 total
Oct 6 - Oct 7
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...
8.4/10 Very Good! (2,974 reviews)
"One of the worst hotel experiences I’ve ever had. Absolutely disgusting and nowhere near worth the price. The room smelled terrible, the bathtub/shower wouldn’t drain, and there wasn’t even any shower gel. I reported the clogged drain to the front desk and specifically asked for the bathroom to be ..."

Reviewed on Oct 5, 2026

Handlery Hotel
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
The price is P8,695 per night from Oct 25 to Oct 26
P8,695
P13,158 total
Oct 25 - Oct 26
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Sheraton San Diego Resort
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
The price is P9,514 per night from Nov 4 to Nov 5
P9,514
P10,936 total
Nov 4 - Nov 5
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in ...
9.2/10 Wonderful! (3,975 reviews)
"Clean Roomy"

Reviewed on Oct 5, 2026

Bay Club Hotel & Marina
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
The price is P10,281 per night from Nov 3 to Nov 4
P10,281
P14,941 total
Nov 3 - Nov 4
includes taxes & fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
9/10 Wonderful! (4,485 reviews)
"The staff was very friendly and helpful. Anything we asked for, someone was right there to take care if it. Everything was very clean and well kept up."

Reviewed on Oct 5, 2026

Hard Rock Hotel San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa West

Find the best Otay Mesa West areas and neighborhoods for the activities you enjoy most.

Downtown San Diego

Petco Park and Port of San Diego are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Gaslamp Quarter

Fantastic nightlife and popular shops are a few of the things travelers enjoy most about Gaslamp Quarter. A visit to Gaslamp Museum at the Davis-Horton House or Nova SD is also recommended, and you can jump aboard the metro at Gaslamp Quarter Station to get around town.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.



Otay Mesa West