Otay Mesa West
San Diego
Visit Otay Mesa West
Popular places to visit
San Diego Zoo
One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.
San Diego Convention Center
During your trip, find out what's happening at San Diego Convention Center, a top convention center in San Diego. Experience the area's entertainment choices and fascinating museums.
SeaWorld
A fun family favourite, where you can get up close to the local marine life, enjoy fun rides and be wowed by the performances.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
Mission Beach
A seaside village and a popular spot for holiday-makers for over a century, which today still retains its antique charm.
Port of San Diego
Explore the waterfront in San Diego with a trip to Port of San Diego. Wander the seaside and beautiful beaches in the area.
Things to do
San Diego Old Town Trolley Hop-On Hop-Off Tour
San Diego Whale Watching & Dolphin Cruise
Sunset Sail Along the San Diego Skyline
San Diego: 3 Hour Whale Watching Cruise
San Diego Whale Watching Cruise
San Diego: Luggage Storage in Marina
Top hotels in Otay Mesa West
Hard Rock Hotel San Diego
Room was very clean and luxurious
Reviewed on Feb 5, 2026
Paradise Point Resort & Spa
All around great experience. Rooms were awesome! Parking was awesome! Workers were awesome! Pools were awesome! Food was awesome! Gym was awesome!
Reviewed on Feb 2, 2026
The DEXTRO Little Italy, BW Premier Collection
Totally better than i expected!!
Reviewed on Feb 6, 2026
The Sofia Hotel
Rooms were clean, the beds were soo comfy, and staff was nice.
Reviewed on Feb 3, 2026
The Dana on Mission Bay
We had such a great time. Everything was good, and the hotel is close to every popular landmarks. Gated parking, gym, room service.
Reviewed on Feb 6, 2026
Hampton Inn & Suites by Hilton San Diego SeaWorld
Staff was awesome facility and rooms were very very clean and breakfast was good. Quiet location.
Reviewed on Feb 3, 2026
Other neighbourhoods around Otay Mesa West
East Village
Travelers choose East Village for its lively bars. Hop aboard the metro at City College Trolley Station or Park and Market Trolley Station and check out top sights like Petco Park.
Gaslamp Quarter
Fantastic nightlife and popular shops are a few of the things travelers enjoy most about Gaslamp Quarter. A visit to Gaslamp Museum at the Davis-Horton House or Lyceum Theatre is also recommended, and you can jump aboard the metro at Gaslamp Quarter Station to get around town.
Downtown San Diego
Petco Park and Port of San Diego are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.
Little Italy
Little Italy is popular for its captivating waterfront views. Explore top sights like Maritime Museum of San Diego and San Diego Bay, and you can get around town on the metro at County Center - Little Italy Station.
North Park
North Park is well-liked for its restaurants. You can also take some time to explore sights in the surrounding area like San Diego Zoo and San Diego Natural History Museum.
Hillcrest
Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.
