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Medical Center District Hotels near San Antonio

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Nov 13 - Nov 15
Next weekend
Nov 20 - Nov 22

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Our top choices for Medical Center District hotels

A spacious lobby with multiple seating areas, a central coffee table, and a view of the upper floors.

1. Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1,533 reviews)
"Nice overnight stay."
United States
Sharon
The price is P5,674
P6,771 total
includes taxes & fees
Nov 15 - Nov 16
Drury Inn & Suites San Antonio Northwest Medical Center
A hotel dining area with multiple tables and chairs, a counter with a coffee machine, and a view of the outside through large windows.

2. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District
8.4 out of 10, Very good, (3,782 reviews)
"Great place to stay"
United States
Gilbert
The price is P5,599
P6,681 total
includes taxes & fees
Nov 10 - Nov 11
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
A modern living room with a fireplace, a flat-screen TV, and a stone accent wall.

3. Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
Medical Center District
9.0 out of 10, Wonderful, (1,113 reviews)
"The breakfast was good and staff was very helpful."
United States
Tina
The price is P5,927
P6,934 total
includes taxes & fees
Nov 15 - Nov 16
Fairfield Inn & Suites by Marriott San Antonio Medical Center
A spacious lobby with a central staircase, seating area, and large windows.

4. San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1,201 reviews)
"Room was clean, very friendly staff"
Canada
Hsiao Tung
The price is P5,876
P7,049 total
includes taxes & fees
Dec 10 - Dec 11
San Antonio Marriott Northwest Medical Center
A modern bar area with wooden bar counters, black bar stools, and pendant lighting.

5. Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1,003 reviews)
"Great property, nice rooms"
United States
Francisca
The price is P5,618
P6,704 total
includes taxes & fees
Nov 26 - Nov 27
Courtyard by Marriott Medical Center San Antonio
A modern kitchen with a large window, wooden counter, and two bar stools.

6. Park Inn by Radisson, Medical Center

Park Inn by Radisson, Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (1,002 reviews)
"Went with my partner, away from the bustle but still close to everything. Great little place."
United States
Jaime
The price is P3,912
P4,577 total
includes taxes & fees
Dec 1 - Dec 2
Park Inn by Radisson, Medical Center
A modern bedroom with a large bed, bedside tables, a desk, and a chair.

7. Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center
2.0 star property
Medical Center District
6.0 out of 10, (1,003 reviews)
"Inexpensive. Above expectations. Quiet, cool, staff friendly."
United States
robert
The price is P2,903
P3,717 total
includes taxes & fees
Nov 10 - Nov 11
Motel 6 San Antonio, TX - Northwest Medical Center
A hotel room with two beds, a desk, a chair, a mirror, and a bathroom.

8. Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (406 reviews)
"It was clean and cheap. I’d stay again but the mattress was old and you could hear and feel the springs sheets and room were clean."
United States
seth
The price is P3,215
P3,762 total
includes taxes & fees
Nov 22 - Nov 23
Studio 6 San Antonio, Tx - Northwest Medical Center
A gas station with a sign for 'Atria Inn & Suites' and a 'Clearance - 12' sign.

9. Atria Inn & Suites

Atria Inn & Suites
2.0 star property
Medical Center District
7.4 out of 10, Good, (321 reviews)
"It’s. Nice place to stay, it’s big and comfortable."
United States
Jose Rolando
The price is P4,369
P5,112 total
includes taxes & fees
Nov 10 - Nov 11
Atria Inn & Suites
A hotel room with two beds, a TV, a desk, and a kitchenette in the background.

10. Studio 6 Extended Stay - San Antonio, TX - Medical Center

Studio 6 Extended Stay - San Antonio, TX - Medical Center
2.0 star property
Medical Center District
6.8 out of 10, (1,001 reviews)
"Good for a short stay traveling through the SA area."
United States
Jerron
The price is P3,152
P3,887 total
includes taxes & fees
Nov 10 - Nov 11
Studio 6 Extended Stay - San Antonio, TX - Medical Center
A building entrance with a glass door, a Pepsi vending machine, and a yellow bollard.

11. OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio
2.0 star property
Medical Center District
7.4 out of 10, Good, (251 reviews)
"great place to stay close to the hospital. Would stay there again"
United States
Melanie
The price is P3,586
P4,554 total
includes taxes & fees
Nov 23 - Nov 24
OYO Inn & Suites Medical Center San Antonio
A bathroom with a granite countertop sink, a mirror, a shower with a glass door, and a toilet.

12. Flex Studios

Flex Studios
2.5 star property
Medical Center District
6.2 out of 10, (580 reviews)
"Extreme need of grab bars by tub. Tub is on an elevated platform. Very difficult to get out."
United States
David
The price is P2,774
P3,311 total
includes taxes & fees
Nov 10 - Nov 11
Flex Studios
A modern bar area with a central island, bar stools, and a kitchen counter with appliances.

13. Hyatt Place San Antonio-Northwest/Medical Center

Hyatt Place San Antonio-Northwest/Medical Center
3.0 star property
3.7 km from Medical Center District
8.4 out of 10, Very good, (1,086 reviews)
"Loved the room and how clean the property was. Would stay here again."
United States
Muri
The price is P5,901
P7,120 total
includes taxes & fees
Nov 26 - Nov 27
Hyatt Place San Antonio-Northwest/Medical Center
A modern lobby with a sofa, patterned chairs, a central ottoman, and a chandelier.

14. Drury Plaza Hotel San Antonio Airport

Drury Plaza Hotel San Antonio Airport
3.0 star property
9 km from Medical Center District
9.4 out of 10, Exceptional, (2,334 reviews)
"Great stay"
United States
garry
The price is P7,187
P8,577 total
includes taxes & fees
Nov 15 - Nov 16
Drury Plaza Hotel San Antonio Airport
A buffet with various food items, including omelets and other dishes, served in metal containers.

15. Holiday Inn Express San Antonio-Airport by IHG

Holiday Inn Express San Antonio-Airport by IHG
2.5 star property
8.9 km from Medical Center District
9.4 out of 10, Exceptional, (1,009 reviews)
"The rooms were very clean and beds were so comfortable."
United States
Lori
The price is P6,368
P7,599 total
includes taxes & fees
Nov 22 - Nov 23
Holiday Inn Express San Antonio-Airport by IHG
A modern hotel with a prominent sign reading "LA QUINTA".

16. La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB
3.0 star property
9 km from Medical Center District
9.2 out of 10, Wonderful, (1,172 reviews)
"Great stay for Lackland Air Force Base."
United States
Lakesha
The price is P6,557
P7,672 total
includes taxes & fees
Nov 29 - Nov 30
La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB
A modern lobby with seating areas, a stone accent wall, and a wooden ceiling.

17. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
2.5 star property
Uptown Central, 9.3 km from Medical Center District
9.0 out of 10, Wonderful, (2,395 reviews)
"Great location near the airport."
United States
Elsa
The price is P4,984
P5,948 total
includes taxes & fees
Nov 12 - Nov 13
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
A hotel with a modern design, featuring a covered parking area and multiple parking spaces.

18. Best Western Medical Center North Inn & Suites Near Six Flags

Best Western Medical Center North Inn & Suites Near Six Flags
2.5 star property
Northwest Side, 5.2 km from Medical Center District
8.2 out of 10, Very good, (1,616 reviews)
"Good budget business hotel."
United States
Vijay
The price is P4,193
P4,906 total
includes taxes & fees
Nov 15 - Nov 16
Best Western Medical Center North Inn & Suites Near Six Flags
A modern kitchen with a central island, built-in appliances, and a coffee station.

19. Wyndham Garden San Antonio Airport

Wyndham Garden San Antonio Airport
3.0 star property
Uptown Central, 9.2 km from Medical Center District
8.6 out of 10, Excellent, (2,056 reviews)
"Good place to stay by the airport."
United States
Antonio
The price is P5,145
P6,140 total
includes taxes & fees
Nov 22 - Nov 23
Wyndham Garden San Antonio Airport
A spacious dining area with multiple tables and chairs, a bar area, and a television mounted on the wall.

20. Hampton Inn & Suites San Antonio Northwest/Medical Center

Hampton Inn & Suites San Antonio Northwest/Medical Center
2.5 star property
Northwest Side, 4.7 km from Medical Center District
8.6 out of 10, Excellent, (1,014 reviews)
"Great place clean room good breakfast nice staff"
United States
Ioana
The price is P5,310
P6,456 total
includes taxes & fees
Nov 22 - Nov 23
Hampton Inn & Suites San Antonio Northwest/Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Medical Center District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A spacious lobby with multiple seating areas, a central coffee table, and a view of the upper floors.
Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
9.2
Wonderful
1,533 reviews
View
A modern living room with a fireplace, a flat-screen TV, and a stone accent wall.
Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
9.0
Wonderful
1,113 reviews
View
A modern bar area with wooden bar counters, black bar stools, and pendant lighting.
Courtyard by Marriott Medical Center San Antonio
3.0 star property
8.8
Excellent
1,003 reviews
View
A spacious lobby with a central staircase, seating area, and large windows.
San Antonio Marriott Northwest Medical Center
3.5 star property
8.6
Excellent
1,201 reviews
View
A hotel dining area with multiple tables and chairs, a counter with a coffee machine, and a view of the outside through large windows.
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
8.4
Very good
3,782 reviews
View

Hotels recommended for families in Medical Center District

A spacious lobby with multiple seating areas, a central coffee table, and a view of the upper floors.

Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1,533)
The price is P5,674
P6,771 total
includes taxes & fees
Nov 15 - Nov 16
Drury Inn & Suites San Antonio Northwest Medical Center

Where to stay in Medical Center District

Find the best Medical Center District areas and neighborhoods for the activities you enjoy most.
A boat tour on a canal with a bridge in the background.

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

A riverside walkway adorned with colorful umbrellas and festive lights.

Uptown Central

While visiting Uptown Central, you might make a stop by sights like Marion Koogler McNay Art Museum and Alamo Quarry Market.

A riverside walkway with colorful umbrellas, a stone bridge, and historic buildings.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

A historic stone building with a central arched doorway, a flagpole with a flag, and a paved courtyard.

Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Crystal Ice Palace.

A historic stone building with a large wooden door, arched windows, and ornate columns.

Stone Oak

Travelers come to Stone Oak for its abundant dining options, and you can see top attractions like Shops at Hardy Oak and Alta Vista at Stone Oak while you're in town.

Top Medical Center District Hotel Reviews

Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

8/10 Good
"The hotel is in a beautiful old bank and has retained all of the charm and elegance of the original building. The rooms are spacious and the pool & hot tub on the roof offer fabulous views. The location is perfect for the River Walk but is quite noisy as it is in town. The kick back is great but very busy. You can spend ages queuing for a drink! Breakfast is great too with a good selection of hot and cold food. We were very disappointed in the housekeeping service. On the first day we went to reception at 3pm to ask why our room hadn't been serviced, to be told that they clean vacated rooms first, then service the rest. The receptionist messaged the housekeeper to ensure we were on the list. So the second day we delayed going to reception and by 6pm, our room hadn't been serviced and we were told that it was too late and the housekeepers had left for the day. We left the following day. Overall I'm not sure we would return."
Ruth 3-night trip
Posted 1 hour ago
Drury Plaza Hotel San Antonio Riverwalk

Frequently asked questions

What is Medical Center District like?
Travelers are sure to enjoy a stay in San Antonio's Medical Center District neighborhood. Consider a visit to Cinemark San Antonio 16 as part of your Medical Center District travel plans.
What's a favorite place to stay in Medical Center District?
Based on our traveler data, La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW is one of the top choices for your stay in Medical Center District. This hotel offers free breakfast and an outdoor pool. Other good options for your stay in the area include Drury Inn & Suites San Antonio Northwest Medical Center and Courtyard by Marriott Medical Center San Antonio.
How many hotels will I be able to find in Medical Center District?
Expedia has 124 hotels and other accommodations in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?
Yes! You'll find that most hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view top deals in Medical Center District.
What can I see and do in this San Antonio neighborhood?
Cinemark San Antonio 16 is an attraction you might want to check out while you're in Medical Center District. Wonderland of the Americas Mall and Regal Huebner Oaks are also worth a visit when you're out sightseeing in San Antonio.

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