Hotels near Roper St. Francis Mount Pleasant Hospital

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 24 - Dec 25
Tomorrow
Dec 25 - Dec 26
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Roper St. Francis Mount Pleasant Hospital hotels

Exterior
Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG

Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG

Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG
2.5 star property
6.7 km from Roper St. Francis Mount Pleasant Hospital
9.0 out of 10, Wonderful, (1000)
"Everything about my stay here has been a delight, clean room, professional & friendly staff "
United States
John
The price is P5,461
P6,171 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG
Lobby
Tru by Hilton Mt Pleasant Charleston

Tru by Hilton Mt Pleasant Charleston

Tru by Hilton Mt Pleasant Charleston
2.5 star property
9.4 km from Roper St. Francis Mount Pleasant Hospital
9.2 out of 10, Wonderful, (1461)
"It was a great hotel!"
United States
Alashia
The price is P5,249
P6,048 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Tru by Hilton Mt Pleasant Charleston
Restaurant
Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms

Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms

Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms
2.5 star property
7.3 km from Roper St. Francis Mount Pleasant Hospital
9.0 out of 10, Wonderful, (1000)
"Great place to stay!!!"
United States
Fredrick
The price is P5,353
P6,174 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms
Dinner served, American cuisine
Cambria Hotel Mount Pleasant – Charleston

Cambria Hotel Mount Pleasant – Charleston

Cambria Hotel Mount Pleasant – Charleston
3.0 star property
9.8 km from Roper St. Francis Mount Pleasant Hospital
9.4 out of 10, Exceptional, (1820)
"Beautiful room, good staff"
United States
Queen
The price is P5,441
P6,276 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Cambria Hotel Mount Pleasant – Charleston
Exterior
Comfort Suites at Isle Of Palms Connector

Comfort Suites at Isle Of Palms Connector

Comfort Suites at Isle Of Palms Connector
2.5 star property
7.4 km from Roper St. Francis Mount Pleasant Hospital
8.2 out of 10, Very Good, (1003)
"The staff was friendly and the room was exceptionally clean. "
United States
RAYMOND
The price is P4,479
P5,348 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Comfort Suites at Isle Of Palms Connector
Exterior
Home2 Suites By Hilton Mt Pleasant Charleston

Home2 Suites By Hilton Mt Pleasant Charleston

Home2 Suites By Hilton Mt Pleasant Charleston
3.0 star property
8.1 km from Roper St. Francis Mount Pleasant Hospital
8.8 out of 10, Excellent, (1001)
"Variety of breakfast options - hotel and room felt clean overall - lots of dining options nearby "
United States
Sarah
The price is P5,730
P6,475 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Home2 Suites By Hilton Mt Pleasant Charleston
Bar (on property)
Hyatt House Charleston / Mount Pleasant

Hyatt House Charleston / Mount Pleasant

Hyatt House Charleston / Mount Pleasant
3.5 star property
9.8 km from Roper St. Francis Mount Pleasant Hospital
9.2 out of 10, Wonderful, (1001)
"Good value and great location."
United States
Howard
The price is P6,518
P7,498 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Hyatt House Charleston / Mount Pleasant
Free daily full breakfast
Residence Inn by Marriott Charleston Mount Pleasant

Residence Inn by Marriott Charleston Mount Pleasant

Residence Inn by Marriott Charleston Mount Pleasant
3.0 star property
7.2 km from Roper St. Francis Mount Pleasant Hospital
8.8 out of 10, Excellent, (183)
"Property was quiet and clean. It was convenient to dining and shopping options. Pool was very well maintained and breakfast was well-stocked and excellent each morning. "
United States
Holly
The price is P6,929
P7,830 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Residence Inn by Marriott Charleston Mount Pleasant
Lobby lounge
Courtyard by Marriott Charleston Mount Pleasant

Courtyard by Marriott Charleston Mount Pleasant

Courtyard by Marriott Charleston Mount Pleasant
3.0 star property
9.4 km from Roper St. Francis Mount Pleasant Hospital
8.8 out of 10, Excellent, (1000)
"We had a very restful stay. The lady that checked us in was very nice. The room was very clean and the beds were comfortable. "
United States
Kathryn
The price is P5,931
P6,702 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Courtyard by Marriott Charleston Mount Pleasant
Restaurant
Homewood Suites by Hilton Charleston - Mt Pleasant

Homewood Suites by Hilton Charleston - Mt Pleasant

Homewood Suites by Hilton Charleston - Mt Pleasant
3.0 star property
7.5 km from Roper St. Francis Mount Pleasant Hospital
8.4 out of 10, Very Good, (1001)
"Courteous staff and great location"
United States
Loushon
The price is P6,516
P7,481 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Homewood Suites by Hilton Charleston - Mt Pleasant
Dining
DoubleTree by Hilton Charleston Mount Pleasant

DoubleTree by Hilton Charleston Mount Pleasant

DoubleTree by Hilton Charleston Mount Pleasant
4.0 star property
10.7 km from Roper St. Francis Mount Pleasant Hospital
9.2 out of 10, Wonderful, (1001)
"Front desk personnel were very nice and professional "
United States
Viviane
The price is P5,489
P6,320 total
includes taxes & fees
Jan 8 - Jan 9, 2026
DoubleTree by Hilton Charleston Mount Pleasant
5 outdoor pools, open 7:00 AM to 10:00 PM, cabanas (surcharge)
Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn
4.0 star property
8.6 km from Roper St. Francis Mount Pleasant Hospital
8.8 out of 10, Excellent, (1003)
"Clean room, excellent facility, perfect location "
United States
Jim
The price is P12,214
P16,420 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn
Private kitchen
TownePlace Suites Charleston Mt. Pleasant

TownePlace Suites Charleston Mt. Pleasant

TownePlace Suites Charleston Mt. Pleasant
3.0 star property
10.7 km from Roper St. Francis Mount Pleasant Hospital
9.0 out of 10, Wonderful, (523)
"Great place to stay. Dog friendly. "
United States
Gabriela
The price is P6,459
P7,299 total
includes taxes & fees
Dec 31 - Jan 1, 2026
TownePlace Suites Charleston Mt. Pleasant
In-room safe, desk, laptop workspace, blackout drapes
The Palms Oceanfront Hotel

The Palms Oceanfront Hotel

The Palms Oceanfront Hotel
3.5 star property
10.4 km from Roper St. Francis Mount Pleasant Hospital
8.2 out of 10, Very Good, (1063)
"Very clean and location was great!! "
United States
Clarisa
The Palms Oceanfront Hotel
Desk, laptop workspace, blackout drapes, free WiFi
Red Roof Inn PLUS+ Mt Pleasant - Patriots Point

Red Roof Inn PLUS+ Mt Pleasant - Patriots Point

Red Roof Inn PLUS+ Mt Pleasant - Patriots Point
2.5 star property
14.4 km from Roper St. Francis Mount Pleasant Hospital
6.8 out of 10, (1003)
"Staff were kind, room was clean."
United States
Mizetta
The price is P3,911
P4,419 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Red Roof Inn PLUS+ Mt Pleasant - Patriots Point
Terrace/patio
Home2 Suites by Hilton Charleston Daniel Island

Home2 Suites by Hilton Charleston Daniel Island

Home2 Suites by Hilton Charleston Daniel Island
3.0 star property
13.5 km from Roper St. Francis Mount Pleasant Hospital
9.4 out of 10, Exceptional, (502)
"So clean, great amenities and excellent breakfast. "
United States
Susan
The price is P7,175
P8,179 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Home2 Suites by Hilton Charleston Daniel Island
Lobby
Hampton Inn Charleston - Daniel Island

Hampton Inn Charleston - Daniel Island

Hampton Inn Charleston - Daniel Island
2.5 star property
13.7 km from Roper St. Francis Mount Pleasant Hospital
9.0 out of 10, Wonderful, (1001)
"The room was clean, the staff was very friendly, breakfast was very good. Will stay here again "
United States
Fernando
The price is P5,730
P6,532 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Hampton Inn Charleston - Daniel Island
Terrace/patio
Holiday Inn Express & Suites Mt. Pleasant by IHG

Holiday Inn Express & Suites Mt. Pleasant by IHG

Holiday Inn Express & Suites Mt. Pleasant by IHG
3.5 star property
14.2 km from Roper St. Francis Mount Pleasant Hospital
9.2 out of 10, Wonderful, (1009)
"Great room layout and wonderful breakfast. "
United States
Clara
The price is P5,050
P5,841 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Express & Suites Mt. Pleasant by IHG
Ballroom
Staybridge Suites Charleston - Mount Pleasant by IHG

Staybridge Suites Charleston - Mount Pleasant by IHG

Staybridge Suites Charleston - Mount Pleasant by IHG
3.0 star property
14.6 km from Roper St. Francis Mount Pleasant Hospital
9.4 out of 10, Exceptional, (1000)
"Great location and very friendly staff"
United States
Malav
The price is P6,518
P7,494 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Staybridge Suites Charleston - Mount Pleasant by IHG
Hallway
Seaside Inn Oceanfront

Seaside Inn Oceanfront

Seaside Inn Oceanfront
2.5 star property
10.5 km from Roper St. Francis Mount Pleasant Hospital
7.6 out of 10, Good, (1001)
"Great place to stay!!! "
United States
Stephanie
Seaside Inn Oceanfront
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Roper St. Francis Mount Pleasant Hospital Hotel Reviews

Comfort Suites at Isle Of Palms Connector

Comfort Suites at Isle Of Palms Connector

10/10 Excellent
"Staff was wonderful. They accommodated an early check-in."
Stephanie 3-night trip
Posted 4 days ago
Comfort Suites at Isle Of Palms Connector

Hotels near other Roper St. Francis Mount Pleasant Hospital attractions

Boone Hall Plantation and Gardens

4.6/5 (518 reviews)
Find out about the history of Mount Pleasant when you take a trip to Boone Hall Plantation and Gardens. Stroll along the area's waterfront, or simply savor its top-notch restaurants.
See properties

Charleston National Golf Club

5.0/5 (1 review)
Enjoy a round of golf in Mount Pleasant at Charleston National Golf Club. Check out the top-notch restaurants or lively bars in this walkable area.
See properties

Frequently asked questions

What's the area like around Roper St. Francis Mount Pleasant Hospital?
Roper St. Francis Mount Pleasant Hospital is located in Mount Pleasant. This historic area is known for its beautiful river views and array of dining options. You'll find 65 hotels and other accommodations within a few miles for a convenient home base.
What's the best place to stay near Roper St. Francis Mount Pleasant Hospital?
Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located 4.1 mi (6.7 km) from Roper St. Francis Mount Pleasant Hospital. Other good options within a few miles include Comfort Suites at Isle Of Palms Connector and Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms.
How many hotels will I find near Roper St. Francis Mount Pleasant Hospital?
Expedia has 65 hotels and other accommodations a few miles from Roper St. Francis Mount Pleasant Hospital.
If I need to cancel the hotel reservation for my stay near Roper St. Francis Mount Pleasant Hospital, will I receive a refund?
Yes! You'll find that most hotel room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and be given a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review the best options available near Roper St. Francis Mount Pleasant Hospital.
What can I see and do near Roper St. Francis Mount Pleasant Hospital?
You can enjoy nature at Goat Island, Dewees Island Beach, or Palmetto Islands County Park. Dunes West Golf and River Club, Charleston National Golf Club, or Snee Farm Country Club are some local sights worth checking out. If you want to see more of the surrounding area, you can plan a visit to Mount Pleasant Towne Centre and Shipyard Park.