Panama City Guest Houses

A city skyline with tall buildings and palm trees along a waterfront.

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Our top choices for Panama City guest houses

A hotel room with a bed, a desk, and a chair. There is a window with a view of palm trees and tall buildings.

1. Casa Orquídea

San Francisco

SANTIAGO

P3,934 total

includes taxes & fees

Nov 29 - Nov 30

2. Room-sofa Bed Stay Rooftop Pool & Gym, A

Santa Ana

Cristian Camilo Betancur

P6,722 total

includes taxes & fees

Nov 16 - Nov 17

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Top Panama City Hotel Reviews

Megapolis Hotel Panamá

10/10 Excellent

"The property is beautiful, the breakfast 9.8/10. The staff very friendly. Room was super clean! I'm already planning my trip there for next year."

Novotel Panama City

10/10 Excellent

"We stayed at Novotel Panama for one night during a layover - I remember seeing Novotel a few times when I was in Panama before but I never stayed there... big mistake! The hotel itself is great - feels new, modern, nicely decorated and very comfortable. But really it was the service from the staff that made a difference - we arrived quite late at night and they still made sure to keep the kitchen open long enough for us to get a bite (which was delicious, BTW). The receptionist was really helpful and FAST which, on a layover, makes a big difference. The rooms were great, bed was big and comfortable, the shower had nice pressure and the amenities in the room had few of those "little things" that just make the overnight and layover so much more "stress-free". I'm definitely staying again!!!"

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