Hotels near North Knoxville Medical Center

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Our top choices for North Knoxville Medical Center hotels

Comfort Inn Powell - Knoxville North

Comfort Inn Powell - Knoxville North
2.5 star property
0.4 km from North Knoxville Medical Center
8.8 out of 10, Excellent, (1004)
"Friendly staff, quiet, good breakfast. Really enjoyed our stay"
United States
antonio
The price is P5,840
P6,672 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Comfort Inn Powell - Knoxville North

Holiday Inn Express & Suites Knoxville-North-I-75 Exit 112 by IHG

Holiday Inn Express & Suites Knoxville-North-I-75 Exit 112 by IHG
2.5 star property
0.3 km from North Knoxville Medical Center
8.4 out of 10, Very Good, (905)
"Great customer service and rooms were good"
United States
Kristi
The price is P5,579
P6,374 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Express & Suites Knoxville-North-I-75 Exit 112 by IHG

La Quinta Inn & Suites by Wyndham Knoxville North I-75

La Quinta Inn & Suites by Wyndham Knoxville North I-75
3.0 star property
0.2 km from North Knoxville Medical Center
7.4 out of 10, Good, (1004)
"The price for my room was better than other places in the area, and I'd stayed at a La Quinta Inn before in Sierra Vista, AZ, so I was familiar with the level of quality, the cleanliness, and excellent service."
United States
Stephen
The price is P5,056
P5,776 total
includes taxes & fees
Dec 23 - Dec 24
La Quinta Inn & Suites by Wyndham Knoxville North I-75

Days Inn by Wyndham Knoxville North

Days Inn by Wyndham Knoxville North
2.5 star property
3 km from North Knoxville Medical Center
7.0 out of 10, Good, (521)
"Quiet stay. Comfortable bed."
United States
Chris
The price is P3,130
P3,701 total
includes taxes & fees
Dec 28 - Dec 29
Days Inn by Wyndham Knoxville North

Baymont by Wyndham Knoxville I-75

Baymont by Wyndham Knoxville I-75
2.5 star property
3.1 km from North Knoxville Medical Center
6.6 out of 10, (1003)
"Clean and quiet facilities."
United States
Rebecca
The price is P3,194
P3,778 total
includes taxes & fees
Dec 28 - Dec 29
Baymont by Wyndham Knoxville I-75

Super 8 by Wyndham Knoxville North/Powell

Super 8 by Wyndham Knoxville North/Powell
2.0 star property
0.7 km from North Knoxville Medical Center
6.4 out of 10, (715)
"Tesla supercharger a short drive way. "
United States
Ian
The price is P3,744
P4,277 total
includes taxes & fees
Dec 27 - Dec 28
Super 8 by Wyndham Knoxville North/Powell

Tru by Hilton Knoxville North I75

Tru by Hilton Knoxville North I75
2.5 star property
4.9 km from North Knoxville Medical Center
9.4 out of 10, Exceptional, (1003)
"Great hotel."
United States
Canay
The price is P5,537
P6,548 total
includes taxes & fees
Dec 28 - Dec 29
Tru by Hilton Knoxville North I75

Hampton Inn & Suites-Knoxville/North I-75

Hampton Inn & Suites-Knoxville/North I-75
2.5 star property
5 km from North Knoxville Medical Center
9.4 out of 10, Exceptional, (1002)
"Staff were very friendly! "
United States
Jennifer
The price is P6,220
P7,356 total
includes taxes & fees
Dec 28 - Dec 29
Hampton Inn & Suites-Knoxville/North I-75

Fairfield Inn & Suites by Marriott Knoxville Northwest

Fairfield Inn & Suites by Marriott Knoxville Northwest
2.5 star property
5.1 km from North Knoxville Medical Center
9.4 out of 10, Exceptional, (448)
"Clean room, Good breakfast options, friendly staff."
United States
Lolak
The price is P6,048
P7,152 total
includes taxes & fees
Dec 28 - Dec 29
Fairfield Inn & Suites by Marriott Knoxville Northwest

The Oliver Hotel

The Oliver Hotel
3.5 star property
12.1 km from North Knoxville Medical Center
9.8 out of 10, Exceptional, (674)
"Great location. "
United States
Dr. Jason C
The price is P8,826
P10,437 total
includes taxes & fees
Jan 4 - Jan 5, 2026
The Oliver Hotel

Hotel Cleo, Knoxville Downtown, a Tribute Portfolio Hotel

Hotel Cleo, Knoxville Downtown, a Tribute Portfolio Hotel
2.0 star property
12.1 km from North Knoxville Medical Center
9.8 out of 10, Exceptional, (117)
"Good balue"
United States
Patrick
The price is P14,739
P17,429 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Hotel Cleo, Knoxville Downtown, a Tribute Portfolio Hotel

Comfort Suites Knoxville North

Comfort Suites Knoxville North
2.5 star property
5 km from North Knoxville Medical Center
9.0 out of 10, Wonderful, (1005)
"Was so happy to stay here- the staff just was as nice as could be"
United States
Billy
The price is P5,449
P6,444 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Comfort Suites Knoxville North

THE TENNESSEAN Hotel

THE TENNESSEAN Hotel
4.0 star property
12.2 km from North Knoxville Medical Center
9.6 out of 10, Exceptional, (1000)
"Check in staff was friendly and we were quickly checked in."
United States
LINDSAY
The price is P11,046
P14,345 total
includes taxes & fees
Jan 4 - Jan 5, 2026
THE TENNESSEAN Hotel

Residence Inn by Marriott Knoxville Downtown

Residence Inn by Marriott Knoxville Downtown
3.0 star property
12.4 km from North Knoxville Medical Center
9.6 out of 10, Exceptional, (147)
"The rain was spotless and lovely and the staff for to delightful. Room was very very nice. One of the nicest places I’ve stayed in a long time."
United States
Paige
The price is P7,458
P8,819 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Residence Inn by Marriott Knoxville Downtown

Spark by Hilton Knoxville North I-75

Spark by Hilton Knoxville North I-75
2.5 star property
5.2 km from North Knoxville Medical Center
8.8 out of 10, Excellent, (118)
"Fantastic stay! Room was very clean and the staff were so attentive and friendly. Would recommend staying here."
United States
rachel
The price is P4,286
P5,068 total
includes taxes & fees
Dec 28 - Dec 29
Spark by Hilton Knoxville North I-75

Holiday Inn Knoxville N - Merchant Drive by IHG

Holiday Inn Knoxville N - Merchant Drive by IHG
3.0 star property
5 km from North Knoxville Medical Center
8.8 out of 10, Excellent, (1002)
"Great place to stay"
United States
Charles
The price is P6,166
P7,291 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Knoxville N - Merchant Drive by IHG

Hyatt Place Knoxville Downtown

Hyatt Place Knoxville Downtown
3.0 star property
12.3 km from North Knoxville Medical Center
9.4 out of 10, Exceptional, (1006)
"We enjoyed our stay. The breakfast was superb, room very clean and comfortable."
United States
Michelle
The price is P6,988
P8,263 total
includes taxes & fees
Dec 30 - Dec 31
Hyatt Place Knoxville Downtown

Embassy Suites by Hilton Knoxville Downtown

Embassy Suites by Hilton Knoxville Downtown
4.0 star property
12.2 km from North Knoxville Medical Center
9.4 out of 10, Exceptional, (770)
"Clean room, wide array & delicious breakfast, & overall gorgeous hotel! "
United States
Amanda
The price is P11,098
P13,124 total
includes taxes & fees
Dec 22 - Dec 23
Embassy Suites by Hilton Knoxville Downtown

Courtyard by Marriott Knoxville Downtown

Courtyard by Marriott Knoxville Downtown
3.0 star property
12.4 km from North Knoxville Medical Center
9.4 out of 10, Exceptional, (594)
"Comfortable bed, great location, nice staff, bistro food was freshly prepared. "
United Kingdom
Alan
The price is P6,694
P7,916 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Courtyard by Marriott Knoxville Downtown

Hampton Inn & Suites Knoxville Papermill Drive

Hampton Inn & Suites Knoxville Papermill Drive
2.5 star property
13.1 km from North Knoxville Medical Center
9.4 out of 10, Exceptional, (1002)
"Friendly staff and fresh accommodations "
United States
Marnie
The price is P6,934
P8,199 total
includes taxes & fees
Dec 28 - Dec 29
Hampton Inn & Suites Knoxville Papermill Drive
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top North Knoxville Medical Center Hotel Reviews

Hotels near other North Knoxville Medical Center attractions

Frequently asked questions

What's the area like around North Knoxville Medical Center?
North Knoxville Medical Center is located in Powell. Travelers like this family-friendly area for its restaurants. If you're looking for a convenient place to stay, check out the 7 hotels and other accommodations you'll find within a mile.
What's the best place to stay near North Knoxville Medical Center?
Adjacent to North Knoxville Medical Center, Comfort Inn Powell - Knoxville North is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. Other good options within a short distance include Holiday Inn Express & Suites Knoxville-North-I-75 Exit 112 by IHG and La Quinta Inn & Suites by Wyndham Knoxville North I-75.
How many hotels will I be able to find close to North Knoxville Medical Center?
Expedia has 7 hotels and other accommodations within a mile from North Knoxville Medical Center.
If I need to cancel the hotel reservation for my stay near North Knoxville Medical Center, will I receive a refund?
Yes! Most hotel room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If your reservation is non-refundable, you might be able to cancel it and be given a refund within 24 hours of booking. Add dates, click "Search", then you can use the "fully refundable" filter to review the top deals on offer near North Knoxville Medical Center.