Uptown - Upper Duval
Key West
Visit Uptown - Upper Duval
Popular places to visit
Southernmost Point
Snap a memorable photograph from the edge of North America at this monumental landmark.
South Beach
The southernmost beach in the continental United States is a convenient sandy enclave, just minutes from the center of town.
Key West Butterfly and Nature Conservatory
With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.
Things to do
Shark and Wildlife Viewing Adventure in Key West
Key West Sunset Cruise & Glass Bottom Eco Tour
Ultimate 90 minute Sea Doo Jet Ski Tour of Key West -Additional Rider Free!
Top hotels in Uptown - Upper Duval
Southernmost Beach Resort and Guesthouses
Air conditioning was very loud which prevented a higher rating
Reviewed on Nov 10, 2025
The Reach Key West, Curio Collection by Hilton
Yes the room was spotless and staff went out of their way to make sure we were taken care of.
Reviewed on Nov 7, 2025
The Southernmost Inn - Adults Only
I stopped by the office around 1:00 pm; Tamika got me checked in and set up my parking pass early, so all I had to do was pick up my room key when my room was ready at 4:00 pm. Room was pleasant, clean and comfortable; A/C worked very well. Also, very impressed with the Starbucks coffee machine!
Reviewed on Nov 12, 2025
Southwinds Motel
Keep in mind it’s a motel! Staff were very friendly and the place was clean, as was the bathroom. Never entertained the two pools they have but people seemed to enjoy them. I think my only don’t is the property owns a bar next door and if your room is next to it - it can be quite noisy. Otherwise ...
Reviewed on Nov 9, 2025
Orchid Key Inn - Adults Only
Was clean, convenient, great friendly staff, located in a perfect place, just what we needed :)
Reviewed on Nov 11, 2025
Southernmost House
Cozy Hotel ☺️
Reviewed on Nov 4, 2025
Check Uptown - Upper Duval hotel availability
Other neighbourhoods around Uptown - Upper Duval
Old Town Key West
If you're spending some time in Old Town Key West, Duval Street and Saint Mary Star of the Sea are top sights worth seeing.
Downtown Key West
If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.
Bahama Village
Bahama Village is noteworthy for its historic sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.
Casa Marina
While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches.
Key West Historic District
Travelers to Key West Historic District praise its fantastic nightlife. If you've got some more time to explore, be sure to make a stop by Duval Street and Saint Mary Star of the Sea.
White Street Gallery District
When in White Street Gallery District, you can plan a visit to Duval Street and Saint Mary Star of the Sea, some noteworthy sights in the nearby area.
