Uptown - Upper Duval

Key West

Key West Butterfly and Nature Conservatory featuring flowers, animals and zoo animals
Key West Butterfly and Nature Conservatory showing animals, zoo animals and flowers
South Beach featuring a coastal town and a beach as well as a large group of people
South Beach featuring a luxury hotel or resort, swimming and a sandy beach
Key West Butterfly and Nature Conservatory featuring signage

Popular places to visit

Things to do


Top hotels in Uptown - Upper Duval

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
The price is P17,346 per night from Jan 13 to Jan 14
P17,346
P23,810 total
Jan 13 - Jan 14, 2026
includes taxes & fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.6/10 Excellent! (2,935 reviews)
The property is wonderful. Clean, convenient to everything and right on the beach. Cant wait to go back

Reviewed on Dec 22, 2025

Southernmost Beach Resort and Guesthouses
The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton

4 out of 5
1435 Simonton Street Key West FL
The price is P19,221 per night from Jan 13 to Jan 14
P19,221
P25,148 total
Jan 13 - Jan 14, 2026
includes taxes & fees
Book a stay at this beach resort in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.4/10 Very Good! (1,009 reviews)
Clean room Concierge staff was excellent

Reviewed on Dec 22, 2025

The Reach Key West, Curio Collection by Hilton
The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only

3 out of 5
525 United Street Key West FL
The price is P15,711 per night from Jan 5 to Jan 6
P15,711
P20,318 total
Jan 5 - Jan 6, 2026
includes taxes & fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.2/10 Very Good! (1,217 reviews)
Great breakfast especially the Starbucks machine for fresh coffee. Great pools and hot tub. Loved the quaint rooms in the original building.

Reviewed on Dec 24, 2025

The Southernmost Inn - Adults Only
Southwinds Motel

Southwinds Motel

2 out of 5
1321 Simonton Street Key West FL
The price is P14,759 per night from Jan 5 to Jan 6
P14,759
P18,587 total
Jan 5 - Jan 6, 2026
includes taxes & fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,241 reviews)
Did not eat breakfast there

Reviewed on Dec 22, 2025

Southwinds Motel
Douglas House

Douglas House

3 out of 5
419 Amelia St Key West FL
The price is P14,357 per night from Jan 13 to Jan 14
P14,357
P17,767 total
Jan 13 - Jan 14, 2026
includes taxes & fees
Stay at this 3-star guesthouse in Key West. Enjoy free WiFi, free parking, and daily housekeeping. Popular attractions Duval Street and Ernest Hemingway Home ...
9.6/10 Exceptional! (236 reviews)
This property was located close to Duvall street yet was quiet.

Reviewed on Dec 25, 2025

Douglas House
Kona Kai Oasis

Kona Kai Oasis

3 out of 5
630 South Street Key West FL
Stay at this guesthouse in Key West. Enjoy free WiFi, free parking, and a garden. Our guests praise the helpful staff in our reviews. Popular attractions Duval ...
8/10 Very Good! (595 reviews)
Love staying at Mona Kai, peaceful, on the quiet end of Duval St

Reviewed on Dec 11, 2025

Kona Kai Oasis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Uptown - Upper Duval

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Old Town Key West

If you're spending some time in Old Town Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.

Old Town Key West
Harry S. Truman Little White House showing a house and cycling

Bahama Village

Bahama Village is noteworthy for its historic sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.

Bahama Village
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Downtown Key West

If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.

Downtown Key West
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Key West Historic District

Travelers to Key West Historic District praise its fantastic nightlife. If you've got some more time to explore, be sure to make a stop by Duval Street and Key West Cemetery.

Key West Historic District
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Casa Marina

While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches.

Casa Marina
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White Street Gallery District

When in White Street Gallery District, you can plan a visit to Duval Street and Clarence S. Higgs Memorial Beach Park, some noteworthy sights in the nearby area.

White Street Gallery District


Uptown - Upper Duval