Uptown - Upper Duval

Key West

Key West Butterfly and Nature Conservatory featuring flowers, animals and zoo animals
Key West Butterfly and Nature Conservatory showing animals, zoo animals and flowers
South Beach featuring a coastal town and a beach as well as a large group of people
South Beach featuring a luxury hotel or resort, swimming and a sandy beach
Key West Butterfly and Nature Conservatory featuring signage

Top hotels in Uptown - Upper Duval

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street, Key West, FL
The price is P9,854 per night from Oct 29 to Oct 30
P9,854
P15,010 total
Oct 29 - Oct 30
includes taxes & fees
Stay at this 4-star beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the bar in our reviews. ...
8.6/10 Excellent! (2,772 reviews)
"Southernmost resort was wonderful! On the quiet end of duval street but all the action is just a short walk away. The food and drinks at the beach cafe were delicious as well. We ordered the nachos multiple times. You have it all there beach pool dining etc. we will be back."

Reviewed on Sep 23, 2025

Southernmost Beach Resort and Guesthouses
The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton

4 out of 5
1435 Simonton Street, Key West, FL
The price is P11,838 per night from Oct 5 to Oct 6
P11,838
P16,806 total
Oct 5 - Oct 6
includes taxes & fees
Stay at this 4-star beach resort in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.4/10 Very Good! (1,013 reviews)
"Great staff, view and food!"

Reviewed on Sep 24, 2025

The Reach Key West, Curio Collection by Hilton
Southwinds Motel

Southwinds Motel

2 out of 5
1321 Simonton Street, Key West, FL
The price is P7,276 per night from Sep 29 to Sep 30
P7,276
P9,821 total
Sep 29 - Sep 30
includes taxes & fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and a 24-hour front desk. Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,186 reviews)
"The room was nice, & the area was fairly good. Near the Southernmost Point marker. Only downside was the water pressure was pretty weak."

Reviewed on Sep 22, 2025

Southwinds Motel
The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only

3 out of 5
525 United Street, Key West, FL
The price is P5,175 per night from Sep 29 to Sep 30
P5,175
P8,438 total
Sep 29 - Sep 30
includes taxes & fees
Stay at this 3-star hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.2/10 Very Good! (1,176 reviews)
"Handy for popular local area"

Reviewed on Sep 20, 2025

The Southernmost Inn - Adults Only
Santa Maria Suites

Santa Maria Suites

4 out of 5
1401 Simonton St, Key West, FL
The price is P14,307 per night from Sep 29 to Sep 30
P14,307
P18,712 total
Sep 29 - Sep 30
includes taxes & fees
Stay at this 4-star resort in Key West. Enjoy free WiFi, 2 outdoor pools, and a fitness center. Our guests praise the pool and the helpful staff in our reviews. ...
9.6/10 Exceptional! (1,007 reviews)
"The suite we stayed in was just like the pictures. I would stay there again the next time I go to the keys. Karen"

Reviewed on Sep 21, 2025

Santa Maria Suites
Kona Kai Oasis

Kona Kai Oasis

3 out of 5
630 South Street, Key West, FL
Stay at this 3-star guesthouse in Key West. Enjoy free WiFi, free parking, and a garden. Our guests praise the helpful staff in our reviews. Popular attractions ...
8/10 Very Good! (556 reviews)
"Not many towels and the fridge was dirty"

Reviewed on Sep 6, 2025

Get rates
Kona Kai Oasis
See all 2,798 properties in Uptown - Upper Duval
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Uptown - Upper Duval

Default Image

Old Town Key West

If you're spending some time in Old Town Key West, Duval Street and Saint Mary Star of the Sea are top sights worth seeing.

Old Town Key West
Default Image

Downtown Key West

If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.

Downtown Key West
Harry S. Truman Little White House showing a house and cycling

Bahama Village

Bahama Village is noteworthy for its historic sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.

Bahama Village
Default Image

Casa Marina

While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Key West AIDS Memorial.

Casa Marina
Default Image

Key West Historic District

Travelers to Key West Historic District praise its fantastic nightlife. If you've got some more time to explore, be sure to make a stop by Duval Street and Saint Mary Star of the Sea.

Key West Historic District
Default Image

White Street Gallery District

When in White Street Gallery District, you can plan a visit to Duval Street and Saint Mary Star of the Sea, some noteworthy sights in the nearby area.

White Street Gallery District

Uptown - Upper Duval