Uptown - Upper Duval
Key West
Visit Uptown - Upper Duval
Popular places to visit
Southernmost Point
Snap a memorable photograph from the edge of North America at this monumental landmark.
South Beach
The southernmost beach in the continental United States is a convenient sandy enclave, just minutes from the center of town.
Key West Butterfly and Nature Conservatory
With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.
Things to do
Key West Afternoon At The Reef Snorkeling Adventure with Open Bar!
Sunset Sail in Key West with Beverages Included
Half-Day Key West's Ultimate Sandbar Adventure with Mangrove Kayak Tour
Key West Half-Day Fishing Charter
Key West Sandbar Safari & Dolphin Playground Experience With Food & Drinks
Top hotels in Uptown - Upper Duval
Southernmost Beach Resort and Guesthouses
It was a nice place we've stayed at before. Rooms this time were cleaned very late 4 to 5 pm when your trying to get ready for dinner. Ice machine didn't work right outside our door, very loud every 20 minutes trying to drop ice, wake you right out of a sleep. Bar staff amazing and most cleaning ...
Reviewed on Feb 7, 2026
The Reach Key West, Curio Collection by Hilton
Hotel was very nice in all respects, but its location on the beach was the best.
Reviewed on Feb 4, 2026
The Southernmost Inn - Adults Only
Everything was good until I forgot I did not book a Friday night. Staff was over the top obnoxious and rushed so hard I left a new sweatshirt in the closet. My fault but completely uncalled for.
Reviewed on Feb 3, 2026
Southwinds Motel
Rooms were clean. The bed need replaced. The area was great.
Reviewed on Feb 4, 2026
Douglas House
Unique. Cozy. Great staff. Great location. Clean enough.
Reviewed on Feb 5, 2026
Santa Maria Suites
The staff was very helpful and courteous Amenities was good. One guest slept on the sofa. There was no closet space downstairs. She shared the closet on the second floor which was not always convenient
Reviewed on Feb 11, 2026
Check Uptown - Upper Duval hotel availability
Other neighbourhoods around Uptown - Upper Duval
Old Town Key West
If you're spending some time in Old Town Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.
Bahama Village
Bahama Village is noteworthy for its historic sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.
Downtown Key West
If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.
Key West Historic District
Travelers to Key West Historic District praise its fantastic nightlife. If you've got some more time to explore, be sure to make a stop by Duval Street and Ernest Hemingway Home and Museum.
Casa Marina
While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches.
White Street Gallery District
When in White Street Gallery District, you can plan a visit to Duval Street and Clarence S. Higgs Memorial Beach Park, some noteworthy sights in the nearby area.
