A sunny street lined with historic buildings, a 'ONE WAY' sign, and a flagpole with flags.

Luxury Hotels in Key West, Florida

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Key West Luxury Hotels

Tonight
Sep 27 - Sep 28
Tomorrow
Sep 28 - Sep 29
Next weekend
Oct 2 - Oct 4
In two weeks
Oct 9 - Oct 11

Our top choices for Key West luxury hotels

A hotel with a covered entrance, multiple balconies, and palm trees.
A restaurant interior with wooden beams, a bar area, and a colorful ceiling mural.
A covered balcony with white Adirondack chairs and a small table with flowers, overlooking a turquoise sea and distant shoreline.
A waterfront hotel with multiple balconies, a dock, and boats.

1. Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West
Old Town Key West
P16,181
P20,664 total
includes taxes & fees
Sep 29 - Sep 30
Opal Key Resort & Marina, Key West
A pool area with lounge chairs and a cabana.
A balcony with a table set for breakfast, overlooking the sea.
A hotel room with a bed, a sofa, a desk with a computer, a chair, and a view of the sea through large windows.
A dining area with a glass table, clear glass bottles, a bowl of fruit, and a wicker chair.

2. Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort
Key West Historic District
P12,136
P18,503 total
includes taxes & fees
Sep 29 - Sep 30
Ocean Key Resort - A Noble House Resort
A wooden deck with wicker furniture and a glass balustrade overlooking a beach.
A beachside spa with two massage tables under a canopy, overlooking the sea and a pier.
A resort with a pool leading to a beach, surrounded by palm trees and white buildings.
A spacious lobby with green sofas, a coffee table, and a dining area.

3. Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton
Old Town Key West
  • Beachfront luxury graces historic Key West resort with private shore access and spa treatments.
P14,619
P20,664 total
includes taxes & fees
Sep 29 - Sep 30
Casa Marina Key West, Curio Collection by Hilton
A beachfront hotel with a covered patio, palm trees, and a boat on the sand.
A balcony with a view of the ocean, a sofa, and a massage table.
A pool area with lounge chairs and umbrellas, surrounded by palm trees and a building with balconies.
A view through a white-framed window with a decorative white fence, leading to a tiled patio area with a round table.

4. Pier House Resort & Spa

Pier House Resort & Spa
Key West Historic District
P12,856
P18,821 total
includes taxes & fees
Oct 4 - Oct 5
Pier House Resort & Spa
A hotel with a swimming pool, balconies, and a view of the sea.
A beach wedding setup with white chairs, a wooden arch, and lanterns.
A balcony with a view of the ocean, a table, chairs, and a railing.
A marina with jet skis docked in front of a hotel with a dock and a boat in the background.

5. Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa
Key West Historic District
P14,557
P20,734 total
includes taxes & fees
Oct 4 - Oct 5
Hyatt Centric Key West Resort and Spa
A large, white, two-story building with a balcony and a sign reading "The Marker Resort."
A covered outdoor area with a pool, palm trees, and lounge chairs.
A resort with a swimming pool, lounge chairs, umbrellas, and palm trees.
A tropical setting with palm trees and a building with a white facade and dark roof.

6. The Marker Key West Harbor Resort

The Marker Key West Harbor Resort
Key West Historic District
  • Key West resort features 3 pools, poolside bar, and private balconies near the harbor.
P12,268
P17,738 total
includes taxes & fees
Oct 5 - Oct 6
The Marker Key West Harbor Resort
A pool area with lounge chairs and palm trees.
A modern outdoor seating area with a sofa, chairs, and a small table, surrounded by glass doors and a view of greenery.
A reception area with a modern design, featuring a reception desk, a sofa, and a potted plant.
A hotel named "Santa Maria" with a prominent illuminated sign, a glass entrance, and a view of the ocean.

7. Santa Maria Suites

Santa Maria Suites
Old Town Key West
  • Lavish Key West retreat features luxury suites, designer touches, 2 pools, and vibrant bar scene.
P15,556
P21,718 total
includes taxes & fees
Sep 29 - Sep 30
Santa Maria Suites
A garden pathway leading to a white gazebo with pink flowers, surrounded by lush greenery and a white fence.
A bedroom with a large bed, a television on a dresser, and a view of the outdoors through a sliding door.
A colonial-style building with a porch, surrounded by lush tropical vegetation.
A bar area with a counter, chairs, and a clock.

8. The Gardens Hotel

The Gardens Hotel
Old Town Key West
P15,170
P17,066 total
includes taxes & fees
Sep 30 - Oct 1
The Gardens Hotel
A deck with sun loungers and a railing overlooking the sea.
A poolside area with lounge chairs and umbrellas, palm trees, and a view of the sea.
A beach scene with two people relaxing under a white umbrella, a palm tree, and a clear blue sky.
A beachside hotel with rows of blue lounge chairs and white umbrellas, palm trees, and a clear blue sky.

9. Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses
Old Town Key West
  • Coastal elegance meets beachfront luxury at this Key West retreat with 3 pools, spa, and oceanview dining.
P10,262
P16,113 total
includes taxes & fees
Sep 29 - Sep 30
Southernmost Beach Resort and Guesthouses
A beach with a wooden pier, palm trees, and beach umbrellas.
A modern bar area with a central island, white bar stools, and a view of the ocean.
A resort with a pool, lounge chairs, umbrellas, palm trees, and a view of the ocean.
An outdoor dining area with tables set for guests, overlooking a calm sea and a pier.

10. The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton
Old Town Key West
P12,426
P18,197 total
includes taxes & fees
Oct 4 - Oct 5
The Reach Key West, Curio Collection by Hilton
View all properties

Top Key West Hotel Reviews

Fairfield by Marriott Inn & Suites Key West at The Keys Collection

Fairfield by Marriott Inn & Suites Key West at The Keys Collection

10/10 Excellent
"Great stay! The breakfast was excellent, and the staff was very friendly and attentive. The room was clean and comfortable. Everything was very nice overall."
Fan 2-night trip
Posted 2 hours ago
Fairfield by Marriott Inn & Suites Key West at The Keys Collection
Beachside Resort & Residences

Beachside Resort & Residences

8/10 Good
"Property was clean, situated nicely, and had plenty of amenities. Our biggest issue with the property was the lack of attention to items. Our shower head was clogged and had little to no water moving through it, random lights were out in our room, the hot tub didn't heat up nor did the jets turn on, but they kept water in it anyway, several, about 1/4, of the lounge chairs were either ripped or completely unusable. Other than that, everything else was great. Our room was huge with everything you could or would need."
Johnathan David 4-night trip
Posted 3 hours ago
Beachside Resort & Residences
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

8/10 Good
"All good"
Ankur 1-night trip
Posted 3 hours ago
Blue Flamingo Resort Key West
Pier House Resort & Spa

Pier House Resort & Spa

10/10 Excellent
"Great location and superb private beach"
Stian 3-night trip
Posted 3 hours ago
Pier House Resort & Spa
Southwinds Motel

Southwinds Motel

10/10 Excellent
"Wonderful"
Hossein 2-night trip
Posted 5 hours ago
Southwinds Motel
Parrot Key Hotel & Villas

Parrot Key Hotel & Villas

10/10 Excellent
"Excellent getaway spot for families or big groups. We loved it. Had a great time celebrating my bday! ✨"
Angelica 2-night trip
Posted 9 hours ago
Parrot Key Hotel & Villas
La Concha Key West, Autograph Collection

La Concha Key West, Autograph Collection

10/10 Excellent
"Great location"
Mary 5-night trip
Posted 1 day ago
La Concha Key West, Autograph Collection
Winslow's Bungalows - Key West Historic Inns

Winslow's Bungalows - Key West Historic Inns

10/10 Excellent
"From before we arrived we already knew we chose the right place to stay! We had questions about parking our motorcycle on property and there was no hesitation to share information and also connect with us. The staff is great. We are recommending this location and properties to friends and family. Next time we’re in town, 100% this will be the place we stay. Location is great and the property is fun to explore. Thank you all for making our stay memorable!"
Rebecca 2-night trip
Posted 3 days ago
Winslow's Bungalows - Key West Historic Inns

Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Key West?
Known for its ocean views and sunsets, Key West also has some interesting things to see and do including Duval Street and Florida Keys Beaches, so you may want to take in the local sights during your visit.
What's the best luxury place to stay in Key West?
Hilton Key West Resort & Marina is a luxury hotel with 6 outdoor pools and a marina, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale option for your vacation is The Porch on Frances Inn.
When can I expect good weather in Key West?
Planning for the weather is a good way to make your trip to Key West relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July with an average temp of 84°F, while the coldest months are January and February with an average of 73°F. Average annual precipitation for Key West is 38 inches.
What's there to see and do in Key West?
Experience Key West with a stop at Duval Street, Florida Keys Beaches, and Ernest Hemingway Home and Museum. If you have spare time during your trip, you might want to make a stop at Key West Lighthouse and Keeper's Quarters Museum and Harry S. Truman Little White House.

Explore a world of travel with Expedia