East Side Pioneers Hotels near Rochester

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Dec 22 - Dec 23
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Dec 26 - Dec 28
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Our top choices for East Side Pioneers hotels

Exterior
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
East Side Pioneers
8.8 out of 10, Excellent, (892)
"Room was clean and comfortable Staff courteous Comfortable beds Great restaurant"
United States
Matney
The price is P4,698
P5,408 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Lobby
Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
3.5 star property
East Side Pioneers
9.6 out of 10, Exceptional, (546)
"Very courteous staff, loved the valet guy!"
United States
Jean
The price is P10,064
P11,586 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Hilton Rochester Mayo Clinic Area
Fridge, microwave, oven, stovetop
Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham
3.0 star property
East Side Pioneers
9.2 out of 10, Wonderful, (167)
"Great staff, clean room, spacious kitchen and living room."
United States
silvia
The price is P9,095
P10,470 total
includes taxes & fees
Dec 28 - Dec 29
Broadway Plaza, Trademark Collection by Wyndham
Terrace/patio
Hampton Inn Rochester-South

Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.5 star property
3.3 km from East Side Pioneers
9.0 out of 10, Wonderful, (1011)
"We had a wonderful stay!"
United States
Sarah
The price is P4,831
P5,561 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Hampton Inn Rochester-South
Exterior
Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 star property
6.9 km from East Side Pioneers
8.8 out of 10, Excellent, (1004)
"Clean rooms, very friendly staff and just all around homey "
United States
Kathy
The price is P4,287
P4,935 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Express Rochester South - Mayo Area by IHG
Terrace/patio
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
3.0 star property
Downtown Rochester, 1.3 km from East Side Pioneers
9.2 out of 10, Wonderful, (1005)
"Quick and easy check-in, walkable area and nice breakfast and accomodations. Would stay again!"
United States
Elizabeth
The price is P7,575
P8,721 total
includes taxes & fees
Dec 23 - Dec 24
Hyatt House Rochester/Mayo Clinic Area
Front of property - evening/night
Kahler Grand Hotel

Kahler Grand Hotel

Kahler Grand Hotel
3.0 star property
Downtown Rochester, 1.3 km from East Side Pioneers
8.4 out of 10, Very Good, (1839)
"It was just perfect!"
United States
Shannon
The price is P7,875
P9,066 total
includes taxes & fees
Dec 24 - Dec 25
Kahler Grand Hotel
Courtyard
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
4.0 star property
Kutzky Park, 2.3 km from East Side Pioneers
9.4 out of 10, Exceptional, (963)
"Rooms are comfortable and staff was was so professional and helpful."
United States
William
The price is P6,401
P7,486 total
includes taxes & fees
Dec 26 - Dec 27
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Indoor pool, open 7:00 AM to 11:00 PM, sun loungers
AmericInn by Wyndham Rochester

AmericInn by Wyndham Rochester

AmericInn by Wyndham Rochester
2.0 star property
12.2 km from East Side Pioneers
8.8 out of 10, Excellent, (1002)
"Enjoyed our stay, rated breakfast as a erage as we did not try it."
United States
jeanne
The price is P4,442
P5,114 total
includes taxes & fees
Dec 27 - Dec 28
AmericInn by Wyndham Rochester
Breakfast served
Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN
3.0 star property
Downtown Rochester, 1.1 km from East Side Pioneers
8.8 out of 10, Excellent, (853)
"Everything was wonderful! Helpful, friendly staff, great location, nice amenities."
United States
kristi
The price is P6,285
P7,236 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Hilton Garden Inn Rochester Downtown, MN
Serves lunch, dinner, and happy hour
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
3 km from East Side Pioneers
8.2 out of 10, Very Good, (1146)
"Good price, room clean, descent breakfast. I have stayed here several time"
United States
Amy M
The price is P4,286
P4,934 total
includes taxes & fees
Dec 26 - Dec 27
AmericInn by Wyndham Rochester Near Mayo Clinic
Front of property
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
7.3 km from East Side Pioneers
7.2 out of 10, Good, (1025)
"Staff was courteous and breakfast was well stocked."
United States
Doug
The price is P4,122
P4,746 total
includes taxes & fees
Dec 25 - Dec 26
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Property amenity
TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
Downtown Rochester, 1.7 km from East Side Pioneers
9.6 out of 10, Exceptional, (481)
"Room was large, clean, beds were comfortable. Downstairs cafe and seating areas were very comfortable."
United States
Ann
The price is P7,458
P8,586 total
includes taxes & fees
Dec 27 - Dec 28
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Exterior
Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North
2.5 star property
8.2 km from East Side Pioneers
9.2 out of 10, Wonderful, (1004)
"Pool was nice "
Canada
Jesse
The price is P5,249
P6,042 total
includes taxes & fees
Dec 29 - Dec 30
Hampton Inn & Suites Rochester-North
Exterior
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
2.5 star property
Kutzky Park, 2.9 km from East Side Pioneers
8.8 out of 10, Excellent, (765)
"Clean room, friendly staff. The only minus is the lighting in the bathroom, way too dim. "
United States
Stacy
The price is P5,109
P5,882 total
includes taxes & fees
Dec 25 - Dec 26
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Free daily full breakfast
Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
2.0 star property
3.4 km from East Side Pioneers
9.0 out of 10, Wonderful, (898)
"Good breakfast..shuttle service is excellent..super nice staff.."
United States
DALE K
The price is P3,968
P4,569 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Econo Lodge Mayo Clinic Area
Exterior
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
Kutzky Park, 2.7 km from East Side Pioneers
9.2 out of 10, Wonderful, (771)
"Clean room and housekeeping service was excellent"
United States
Dawn
The price is P4,933
P5,679 total
includes taxes & fees
Dec 24 - Dec 25
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Desk, iron/ironing board, free WiFi, bed sheets
Brentwood Inn & Suites

Brentwood Inn & Suites

Brentwood Inn & Suites
2.5 star property
Downtown Rochester, 1.5 km from East Side Pioneers
8.8 out of 10, Excellent, (1007)
"Convenient, clean location and friendly staff"
United States
Kaushika
The price is P6,606
P7,605 total
includes taxes & fees
Dec 23 - Dec 24
Brentwood Inn & Suites
Exterior
Spark by Hilton Rochester South

Spark by Hilton Rochester South

Spark by Hilton Rochester South
3.0 star property
7 km from East Side Pioneers
9.4 out of 10, Exceptional, (326)
"Great place"
United States
Abidemi
The price is P4,141
P4,767 total
includes taxes & fees
Dec 28 - Dec 29
Spark by Hilton Rochester South
Desk, blackout drapes, iron/ironing board, free cribs/infant beds
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area
3.5 star property
Downtown Rochester, 1.4 km from East Side Pioneers
8.0 out of 10, Very Good, (1522)
"Clean room, good room service and good breakfast."
United States
Donald
The price is P7,458
P8,586 total
includes taxes & fees
Dec 29 - Dec 30
Kahler Inn and Suites - Mayo Clinic Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in East Side Pioneers

Find the best East Side Pioneers areas and neighborhoods for the activities you enjoy most.
Rochester showing a city and skyline
Photo by Howard Lower Photography
Open Photo by Howard Lower Photography

Downtown Rochester

If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Civic Theater are top sights worth seeing.

Kutzky Park

While there might not be top attractions in Kutzky Park, you can explore the larger area and discover places like Soldiers Field Veterans Memorial and Mayo Civic Center.

Rochester which includes forests and a river or creek
Photo by Chad Johnson
Open Photo by Chad Johnson

Historic Southwest

While visiting Historic Southwest, you might make a stop by sights like Soldiers Field Veterans Memorial and Plummer House.

Slatterly Park

Slatterly Park might not have many top sights, but Rochester Art Center and Soldiers Field Veterans Memorial are two attractions nearby that you can check out.

Folwell

While there might not be top attractions in Folwell, you can explore the larger area and discover places like Soldiers Field Veterans Memorial and Apache Mall.

Top East Side Pioneers Hotel Reviews

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

10/10 Excellent
"Clean hotel! "
Marissa 1-night trip
Posted 21 hours ago
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Frequently asked questions

What's it like in East Side Pioneers?
Travelers are sure to enjoy a stay in Rochester's East Side Pioneers neighborhood. Are you looking for East Side Pioneers travel tips? Be sure to check out Rochester Art Center and Rochester Civic Theater while you're in the neighborhood.
What's a favorite place to stay in East Side Pioneers?
Based on Expedia customer reviews, Hilton Rochester Mayo Clinic Area is the highest ranked property in East Side Pioneers. This hotel is a short 6-minute walk from Mayo Clinic, and it offers a full-service spa and 2 restaurants. Another favorite option in the neighborhood is Hotel Indigo Rochester – Mayo Clinic Area by IHG.
How many hotels will I be able to find in East Side Pioneers?
If you're searching for places to stay in Rochester, choose from one of Expedia's 17 hotels and other accommodations in East Side Pioneers.
If I need to cancel my hotel reservation in East Side Pioneers, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to review top deals in East Side Pioneers.
What can I see and do in this Rochester neighborhood?
Spend some time exploring the natural setting of East Side Pioneers with a visit to Silver Lake Park and Mayo Park. You could also plan a visit to Rochester Art Center or Rochester Civic Theater while you're in the neighborhood. A few places to visit in the area around East Side Pioneers include Mayo Civic Center, Rochester Public Library, and Shops University Square. While you're out sightseeing, Plummer Building and Soldiers Field Veterans Memorial are a couple of additional sights to visit in Rochester.

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