East Prairie Hotels

Days Inn and Suites by Wyndham Sikeston, located 11 mi (17.7 km) from the heart of East Prairie, is a top choice for your stay based on our traveler data. Other good options for your visit to the area are Drury Inn & Suites Sikeston, MO and Pear Tree Inn Sikeston. See all available top hotels, or vacation rentals in East Prairie.

Yes! The majority of hotel room reservations are fully refundable if you cancel before the hotel’s cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in East Prairie.

To access more information about rescheduling or cancelling your trip to East Prairie, click here.

Best Western Plus Sikeston: Features free full breakfast, a pool, and free parking. Pear Tree Inn Sikeston and Drury Inn & Suites Sikeston, MO are a couple of other choices that offer an onsite pool. View all hotels with pools in East Prairie.

Candlewood Suites Cape Girardeau is one of the top choices for your stay and is a popular hotel, featuring an indoor pool and free WiFi. It's located 4.4 mi (7 km) from Cape Girardeau Municipal Airport.

Visitors are sure to enjoy all that East Prairie has to offer. There are 30 hotels and other accommodations in the surrounding area. Find out more about East Prairie.

Places to visit in the wider area include Big Oak Tree State Park, Columbus-Belmont State Park, and The Book Bug. You'll also find River Ridge Winery and New Madrid Historical Museum in the area. Check out what more to see and do in Expedia's East Prairie guide.

The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for East Prairie is 60 inches.