East Prairie Hotels

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Tonight
Nov 18 - Nov 19
Tomorrow
Nov 19 - Nov 20
This weekend
Nov 21 - Nov 23
Next weekend
Nov 28 - Nov 30

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Top 10 trending East Prairie hotels

1 bedroom, desk, laptop workspace, blackout drapes
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2.0 star property
Sikeston
7.2 out of 10, Good, (1001)
"A great stay in every aspect. "
United States
Gertrude
The price is P3,706
P4,224 total
includes taxes & fees
Nov 23 - Nov 24
Days Inn and Suites by Wyndham Sikeston
Exterior
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 star property
Sikeston
9.0 out of 10, Wonderful, (426)
"Room was clean and cozy, the check in-out staff were really nice and asked about our stay as well and the breakfast was a nice variety."
United States
Doncheial
The price is P5,610
P6,352 total
includes taxes & fees
Nov 30 - Dec 1
Hampton Inn Sikeston
Exterior
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 star property
Sikeston
8.6 out of 10, Excellent, (439)
"Well maintained property. We’ll stop again should we need to."
United States
Janet DeJean
The price is P5,906
P6,687 total
includes taxes & fees
Dec 19 - Dec 20
Holiday Inn Express & Suites Sikeston Southwest by IHG
Free daily full breakfast
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 star property
Sikeston
8.4 out of 10, Very Good, (1003)
"Very convenient and great breakfast "
United States
Duwaine
The price is P4,958
P5,651 total
includes taxes & fees
Nov 23 - Nov 24
Best Western Plus Sikeston
Exterior
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 star property
Sikeston
8.4 out of 10, Very Good, (708)
"Stayed one night. Good rate for the Hotel "
United States
Paul
The price is P3,564
P4,063 total
includes taxes & fees
Nov 23 - Nov 24
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Lobby
Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America

2.5 star property
Union City
9.2 out of 10, Wonderful, (299)
"Awesome room wonderful breakfast great staff"
United States
Thomas
The price is P4,959
P5,888 total
includes taxes & fees
Dec 16 - Dec 17
Sleep Inn at Discovery Park of America
Front of property - evening/night
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
Charleston
6.6 out of 10, (607)
"Staff was great! Room was nice. "
United States
Lana
The price is P3,306
P3,668 total
includes taxes & fees
Nov 23 - Nov 24
Super 8 by Wyndham Charleston/Sikeston East MO
Lobby
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 star property
Sikeston
9.4 out of 10, Exceptional, (1002)
"Everything was clean, staff was friendly "
United States
Matthew
The price is P4,537
P5,215 total
includes taxes & fees
Dec 9 - Dec 10
Pear Tree Inn Sikeston
Desk, laptop workspace, blackout drapes, free WiFi
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

2.0 star property
Sikeston
6.6 out of 10, (559)
"The room was good a/c kept it cold "
United States
Mary
The price is P3,695
P4,211 total
includes taxes & fees
Dec 9 - Dec 10
Super 8 by Wyndham Sikeston/Miner Area
Seasonal outdoor pool
Hospitality House Union City I 69 / US 51

Hospitality House Union City I 69 / US 51

2.5 star property
Union City
6.8 out of 10, (358)
"Easy to check in.. Clean Room..Lots of food options near by.. "
United States
Pooran
The price is P3,206
P3,808 total
includes taxes & fees
Dec 17 - Dec 18
Hospitality House Union City I 69 / US 51
Exterior
Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55

2.5 star property
Sikeston
8.4 out of 10, Very Good, (277)
"Room was clean, breakfast was very good. "
United States
Connie
The price is P4,969
P5,664 total
includes taxes & fees
Dec 7 - Dec 8
Comfort Inn & Suites Sikeston I-55
Property amenity
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1005)
"Clean room, great location and friendly staff"
United States
Mark
The price is P5,656
P6,504 total
includes taxes & fees
Nov 22 - Nov 23
Drury Inn & Suites Sikeston, MO
Lobby
Quality Inn Union City US 51

Quality Inn Union City US 51

2.5 star property
Union City
8.4 out of 10, Very Good, (482)
"The Staff for sure is what keeps me coming back! Plus the rooms are very clean!"
United States
Walter
The price is P3,957
P4,699 total
includes taxes & fees
Dec 7 - Dec 8
Quality Inn Union City US 51
Bar (on property)
Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston

2.5 star property
Sikeston
9.2 out of 10, Wonderful, (35)
"THE ROOM WAS SPOTLESS, CLEAN LOBBY, WARM AND LOT OF VARITY BREAKFAST, STAFF IS SO NICE."
United States
AHMAD
The price is P5,952
P6,739 total
includes taxes & fees
Nov 29 - Nov 30
Fairfield Inn & Suites by Marriott Sikeston
Reception
Country Hearth Inn & Suites Union City

Country Hearth Inn & Suites Union City

2.5 star property
Union City
8.6 out of 10, Excellent, (545)
"Fantastic "
United States
Michael
The price is P4,242
P5,038 total
includes taxes & fees
Nov 19 - Nov 20
Country Hearth Inn & Suites Union City
Terrace/patio
Hampton Inn Union City

Hampton Inn Union City

2.5 star property
Union City
9.4 out of 10, Exceptional, (160)
"Staff was very friendly, room was quiet, easy to get to. Room was clean and comfortable❤️"
United States
Diana
The price is P5,610
P6,662 total
includes taxes & fees
Nov 24 - Nov 25
Hampton Inn Union City
Lobby
Quality Inn Cairo I-57

Quality Inn Cairo I-57

2.5 star property
Cairo
6.6 out of 10, (272)
"Break fast was excellent "
United States
Uma
The price is P4,061
P4,506 total
includes taxes & fees
Nov 30 - Dec 1
Quality Inn Cairo I-57
Bar (on property)
TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston

3.0 star property
Sikeston
8.4 out of 10, Very Good, (5)
"Great hotel! Very clean, quiet, plenty of amenities, pool was clean, breakfast in the morning was good with lots of options. I would definitely stay here again. "
United States
Scott
The price is P7,130
P8,073 total
includes taxes & fees
Dec 18 - Dec 19
TownePlace Suites by Marriott Sikeston
Free daily buffet breakfast
Holiday Inn Express & Suites Union City by IHG

Holiday Inn Express & Suites Union City by IHG

2.5 star property
Union City
9.2 out of 10, Wonderful, (305)
"It was a great hotel! No complaints. Loved the front staff!"
United States
Felicia
The price is P5,669
P6,732 total
includes taxes & fees
Dec 19 - Dec 20
Holiday Inn Express & Suites Union City by IHG
Gazebo
Travel Inn

Travel Inn

2.5 star property
Marston
5.8 out of 10, (115)
"Had a great time loved it "
United States
Shyianne
Travel Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular East Prairie attractions

Big Oak Tree State Park

3.8/5 (8 reviews)
You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.
See properties

Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artifacts tell the story of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

See all hotels in East Prairie
Bridge over Mississippi River, New Orleans in background

Top East Prairie Hotel Reviews

Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

10/10 Excellent
"Grat as usual!"
Robert 1-night trip
Posted 7 days ago
Pear Tree Inn Sikeston

More cheap stays in East Prairie

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO
The price is P3,706 per night from Nov 23 to Nov 24
P3,706
P4,224 total
Nov 23 - Nov 24
includes taxes & fees
7.2/10 Good! (1,000 reviews)

Frequently asked questions

What's the best place for a stay in East Prairie?
Drury Inn & Suites Sikeston, MO, located 11.4 mi (18.4 km) from the heart of East Prairie, is a top choice for your stay based on our traveler data. Other good options for your visit to the area are Hampton Inn Sikeston and Sleep Inn at Discovery Park of America. See all available top hotels, or vacation rentals in East Prairie.
If I need to cancel my hotel reservation in East Prairie, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in East Prairie.
What's it like to stay in East Prairie?
Visitors are sure to enjoy all that East Prairie has to offer. There are 32 hotels and other accommodations in the surrounding area. Find out more about East Prairie.
What should I do while I'm visiting East Prairie?
The picturesque setting of Big Oak Tree State Park and Mississippi River exemplify the area's natural beauty. You'll also find Sikeston Depot Museum and New Madrid Historical Museum in the area. Check out what more to see and do in Expedia's East Prairie guide.
What's the weather like in East Prairie?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for East Prairie is 60 inches.

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