East Prairie Hotels
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Go beyond your typical stay in East Prairie
Family friendly
Check prices for these dates
Top 10 trending East Prairie hotels

Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
7.2 out of 10, Good, (1002)
The price is P4,202
P4,790 total
includes taxes & fees
Aug 5 - Aug 6

Hampton Inn Sikeston
Hampton Inn Sikeston
8.8 out of 10, Excellent, (369)
The price is P6,296
P7,129 total
includes taxes & fees
Aug 24 - Aug 25

Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHG
8.6 out of 10, Excellent, (420)
The price is P6,514
P7,376 total
includes taxes & fees
Sep 1 - Sep 2

Best Western Plus Sikeston
Best Western Plus Sikeston
8.4 out of 10, Very Good, (1003)
The price is P5,125
P5,841 total
includes taxes & fees
Aug 10 - Aug 11

Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Sikeston/Miner Area
6.6 out of 10, (545)
The price is P3,868
P4,408 total
includes taxes & fees
Aug 10 - Aug 11

Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MO
6.6 out of 10, (577)
The price is P3,520
P3,907 total
includes taxes & fees
Aug 3 - Aug 4
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Learn more about East Prairie
Explore attractions like Big Oak Tree State Park and Mississippi River as you discover things to see and do in East Prairie.
Top East Prairie Hotel Reviews

New Orleans Inn Portageville
10/10 Excellent
More cheap stays in East Prairie
More cheap stays in East Prairie

Best Western Plus Sikeston
120 S Interstate Drive, Sikeston, MO
The price is P5,125 per night from Aug 10 to Aug 11
P5,125
P5,841 total
Aug 10 - Aug 11
includes taxes & fees
8.2/10 Very Good! (1,015 reviews)
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Hotels Near East Prairie, Missouri
- Sikeston Hotels
- Southern Illinois Hotels
- Union City Hotels
- Southeastern United States Hotels
- Charleston Hotels
- Cairo Hotels
- Tiptonville Hotels
- Marston Hotels
- Western Kentucky Hotels
- Hornbeak Hotels
- Portageville Hotels
- Western Tennessee Hotels
- Fulton Hotels
- Southeast Missouri Hotels
- Miner Hotels
- Central United States Hotels
- New Madrid Hotels
- Wickliffe Hotels
- Samburg Hotels
- Benton Hotels
More ways to book
Expedia's Latest Trends
Hotels
- Hotels with shuttle in Tinley Park
- Hotels with smoking rooms in Evansville
- Hotels in Ithaca
- Hotels with smoking rooms in Columbia
- Hotels in Antioch
- Hotels with free parking in Honolulu
- Hotels in Escondido
- Hotels with smoking rooms in White Plains
- Hotels with smoking rooms in Dubuque
- Hotels with smoking rooms in Joplin
- Hotels in Honolulu