East Prairie Hotels

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Top 10 trending East Prairie hotels

Sleep Inn at Discovery Park of America

2.5 star property
9.0 out of 10, Wonderful, (259)
"The staff was super respectful and kind, especially in conflict situations! we appreciate them very much. "
The price is P4,912
P5,833 total
includes taxes & fees
Sep 7 - Sep 8
Sleep Inn at Discovery Park of America

Holiday Inn Express & Suites Union City by IHG

2.5 star property
9.2 out of 10, Wonderful, (284)
"This hotel was directly across from the Discovery Park of America. Definitely recommend staying there!"
The price is P6,621
P7,862 total
includes taxes & fees
Aug 31 - Sep 1
Holiday Inn Express & Suites Union City by IHG

Hospitality House Union City I 69 / US 51

2.5 star property
6.8 out of 10, (323)
"Filthy "
The price is P3,106
P3,688 total
includes taxes & fees
Sep 16 - Sep 17
Hospitality House Union City I 69 / US 51

Country Hearth Inn & Suites Union City

2.5 star property
8.6 out of 10, Excellent, (530)
"Very good!"
The price is P4,109
P4,880 total
includes taxes & fees
Aug 19 - Aug 20
Country Hearth Inn & Suites Union City

Hampton Inn Union City

2.5 star property
9.4 out of 10, Exceptional, (148)
"It was peaceful and quiet"
The price is P6,404
P7,605 total
includes taxes & fees
Aug 31 - Sep 1
Hampton Inn Union City

Quality Inn Union City US 51

2.5 star property
8.4 out of 10, Very Good, (462)
"Nice place. Everything went as should and no hidden fees. "
The price is P3,833
P4,551 total
includes taxes & fees
Aug 31 - Sep 1
Quality Inn Union City US 51

Quality Inn Cairo I-57

2.5 star property
6.6 out of 10, (264)
"The hotel is in need of some serious upkeep and cleaning. It is in fairly poor condition, but it the only hotel in town."
The price is P3,948
P4,382 total
includes taxes & fees
Sep 8 - Sep 9
Quality Inn Cairo I-57

Eagle Inn Charleston

2.0 star property
6.8 out of 10, (100)
"Comfortable bed, easy access to room"
The price is P3,641
P4,041 total
includes taxes & fees
Sep 1 - Sep 2
Eagle Inn Charleston

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
6.6 out of 10, (582)
"Rooms was clean "
The price is P3,348
P3,715 total
includes taxes & fees
Sep 8 - Sep 9
Super 8 by Wyndham Charleston/Sikeston East MO

Quality Inn Charleston - Sikeston

2.5 star property
6.8 out of 10, (397)
"I consistently choose to stay there due to positive past encounters."
The price is P3,840
P4,262 total
includes taxes & fees
Sep 8 - Sep 9
Quality Inn Charleston - Sikeston

Reelfoot Lake Inn

2.0 star property
7.2 out of 10, Good, (446)
"Staff was amazing and available anytime. Other than incredible bug problem my only real issue is the pet fee is $20 not $10 and having a pet forces you in a smoking room which had i known certainly would have changed my plans. Location though is perfect"
The price is P4,052
P4,790 total
includes taxes & fees
Aug 19 - Aug 20
Reelfoot Lake Inn

Country Yard Inn and Suite

2.0 star property
6.8 out of 10, (106)
"The property was well kept but lacked convenience of food and computer."
The price is P3,104
P3,693 total
includes taxes & fees
Aug 19 - Aug 20
Country Yard Inn and Suite

Days Inn and Suites by Wyndham Sikeston

2.0 star property
7.2 out of 10, Good, (1002)
"The room was awesome and the building had a historical thing about it."
The price is P3,785
P4,314 total
includes taxes & fees
Aug 20 - Aug 21
Days Inn and Suites by Wyndham Sikeston

Best Western Plus Sikeston

2.5 star property
8.4 out of 10, Very Good, (1004)
"We enjoyed our stay and the breakfast was good!"
The price is P5,029
P5,732 total
includes taxes & fees
Aug 24 - Aug 25
Best Western Plus Sikeston

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1004)
"Great location "
The price is P5,136
P5,905 total
includes taxes & fees
Aug 24 - Aug 25
Drury Inn & Suites Sikeston, MO

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 star property
8.4 out of 10, Very Good, (669)
"Everything was nice"
The price is P3,453
P3,935 total
includes taxes & fees
Aug 19 - Aug 20
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Comfort Inn & Suites Sikeston I-55

2.5 star property
8.4 out of 10, Very Good, (271)
"The facility was very nice. "
The price is P4,803
P5,474 total
includes taxes & fees
Aug 24 - Aug 25
Comfort Inn & Suites Sikeston I-55

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1009)
"Very nice property Friendly helpful staff"
The price is P4,566
P5,249 total
includes taxes & fees
Aug 22 - Aug 23
Pear Tree Inn Sikeston

Super 8 by Wyndham Sikeston/Miner Area

2.0 star property
6.6 out of 10, (551)
"I enjoyed our stay"
The price is P3,596
P4,099 total
includes taxes & fees
Aug 19 - Aug 20
Super 8 by Wyndham Sikeston/Miner Area

Hampton Inn Sikeston

2.5 star property
8.8 out of 10, Excellent, (374)
"Great location and clean room. Plenty of food and shopping nearby."
The price is P6,064
P6,866 total
includes taxes & fees
Sep 7 - Sep 8
Hampton Inn Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artifacts tell the story of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

Top East Prairie Hotel Reviews

Frequently asked questions

What's the best place for a stay in East Prairie?

Best Western Plus Sikeston, located 11.1 mi (17.9 km) from the heart of East Prairie, is a top choice for your stay based on our traveler data. Other good options for your visit to the area are Drury Inn & Suites Sikeston, MO and Days Inn and Suites by Wyndham Sikeston. See all available top hotels, or vacation rentals in East Prairie.

If I need to cancel my hotel reservation in East Prairie, will I receive a refund?

Yes! The majority of hotel room reservations are fully refundable if you cancel before the hotel’s cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in East Prairie.

Where can I learn more about changing or cancelling my trip to East Prairie?

To access more information about rescheduling or cancelling your trip to East Prairie, click here.

What's the best hotel for staying near Cape Girardeau Municipal Airport (CGI)?

Candlewood Suites Cape Girardeau is one of the top choices for your stay and is a popular hotel, featuring an indoor pool and free WiFi. It's located 4.4 mi (7 km) from Cape Girardeau Municipal Airport.

What's it like to stay in East Prairie?

Visitors are sure to enjoy all that East Prairie has to offer. There are 30 hotels and other accommodations in the surrounding area. Find out more about East Prairie.

What should I do while I'm visiting East Prairie?

The picturesque setting of Big Oak Tree State Park and Mississippi River exemplify the area's natural beauty. You'll also find Sikeston Depot Museum and New Madrid Historical Museum in the area. Check out what more to see and do in Expedia's East Prairie guide.

What's the weather like in East Prairie?

The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for East Prairie is 60 inches.