East Prairie Hotels

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Our top choices for East Prairie hotels

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (616)
This Charleston motel offers complimentary on-the-go breakfast and WiFi for a hassle-free stay. Guests appreciate the helpful staff and free parking. Located within driving distance of Cape Girardeau Municipal Airport for easy regional access.

"Staff was great! Room was nice. "
United States
Lana
The price is P3,655
P4,056 total
includes taxes & fees
Jan 6 - Jan 7
Super 8 by Wyndham Charleston/Sikeston East MO

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1005)
Located just off the highway near Sikeston dining and shopping, this hotel offers both indoor and outdoor pools for year-round swimming. Guests praise the peaceful atmosphere, helpful staff, and complimentary breakfast, parking, and WiFi.

"Great place. Friendly staff clean"
United States
Jeff
The price is P5,297
P6,090 total
includes taxes & fees
Jan 11 - Jan 12
Drury Inn & Suites Sikeston, MO

Hospitality House Union City I 69 / US 51

Hospitality House Union City I 69 / US 51
2.5 star property
Union City
6.8 out of 10, (372)
Business travelers love this Union City hotel with a seasonal outdoor pool and on-site restaurant. Enjoy complimentary breakfast, WiFi, and parking. The helpful staff receives excellent reviews, and nearby County Market Place and Reelfoot Shopping Center offer local attractions.

"Very friendly staff. Upgraded my room to accommodate my first floor request. Room was clean and very comfortable. I would definitely stay here again. "
United States
Barb
The price is P3,203
P3,804 total
includes taxes & fees
Feb 3 - Feb 4
Hospitality House Union City I 69 / US 51

Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America
2.5 star property
Union City
9.2 out of 10, Wonderful, (327)
Located in Union City, this hotel offers convenient access to Discovery Park of America. Enjoy free breakfast, WiFi, and parking. Jump into the indoor pool or get active in the 24-hour fitness center, making your Tennessee adventure complete.

"The rooms are big and the property is spotless!"
United States
debbie
The price is P4,753
P5,644 total
includes taxes & fees
Feb 1 - Feb 2
Sleep Inn at Discovery Park of America

Quality Inn Union City US 51

Quality Inn Union City US 51
2.5 star property
Union City
8.4 out of 10, Very Good, (489)
Unwind at this Union City hotel offering a seasonal outdoor pool and hot tub for relaxation. Just a short distance from County Market Place and Reelfoot Shopping Center, guests enjoy free breakfast, WiFi, and parking.

"Nice room"
Mexico
José Ricardo
The price is P3,953
P4,694 total
includes taxes & fees
Feb 1 - Feb 2
Quality Inn Union City US 51

Holiday Inn Express & Suites Union City by IHG

Holiday Inn Express & Suites Union City by IHG
2.5 star property
Union City
9.4 out of 10, Exceptional, (310)
Experience comfort in the entertainment district of Union City at this welcoming hotel. Start your day with free breakfast before exploring nearby Discovery Park of America. After sightseeing, unwind in the indoor pool or maintain your routine at the 24-hour fitness center.

"Rooms were spotless and comfortable. The bathroom had all the amenities. Great view. Awesome buffet breakfast to wake up to. "
United States
Rickey Smith
The price is P6,181
P7,339 total
includes taxes & fees
Feb 1 - Feb 2
Holiday Inn Express & Suites Union City by IHG

Best Western Plus Sikeston

Best Western Plus Sikeston
2.5 star property
Sikeston
8.4 out of 10, Very Good, (1007)
Located in Sikeston, this hotel offers an indoor pool for relaxing swims after a day of exploring. Near Central Park and the Sikeston Depot Museum, guests praise the delicious free breakfast and attentive service.

"Great stay, everything was clean and comfortable. "
United States
Charles
The price is P4,652
P5,303 total
includes taxes & fees
Jan 9 - Jan 10
Best Western Plus Sikeston

Country Hearth Inn & Suites Union City

Country Hearth Inn & Suites Union City
2.5 star property
Union City
8.6 out of 10, Excellent, (550)
Discover convenience at this friendly Union City motel, where free breakfast and parking enhance every stay. Explore County Market Place and Reelfoot Shopping Center nearby. Guests consistently praise the clean rooms and helpful staff.

"Roaches!"
United States
Teresa
Country Hearth Inn & Suites Union City

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (456)
Take a refreshing dip in the indoor pool or maintain your routine at the fitness center. Free breakfast, WiFi, and parking enhance your stay. Central Park and Sikeston Depot Museum are just moments away from this welcoming retreat.

"clean room, comfy bedding, nice staff, convenient location "
United States
Alexa
The price is P5,934
P6,719 total
includes taxes & fees
Jan 11 - Jan 12
Hampton Inn Sikeston

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (105)
Discover relaxation at this Charleston motel offering complimentary WiFi and parking. The onsite health club provides fitness options after exploring local attractions. Cape Girardeau Municipal Airport is just a 43-minute drive away.

"Middle of nowhere hotel was ok"
United States
David
The price is P3,561
P3,951 total
includes taxes & fees
Jan 6 - Jan 7
Eagle Inn Charleston

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very Good, (733)
This welcoming motel offers clean rooms praised by guests, plus convenient amenities including free WiFi and parking. The 24-hour front desk ensures assistance anytime during your stay in charming Portageville.

"Friendly sta"
United States
Melissa
New Orleans Inn Portageville

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.2 out of 10, Good, (1003)
This tranquil Sikeston hotel offers complimentary on-the-go breakfast and WiFi, plus convenient access to Central Park and Sikeston Depot Museum. Guests appreciate the helpful staff, clean rooms, and free parking, with a fitness center for morning workouts.

"A great stay in every aspect. "
United States
Gertrude
The price is P3,702
P4,220 total
includes taxes & fees
Jan 11 - Jan 12
Days Inn and Suites by Wyndham Sikeston

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
Sikeston
6.8 out of 10, (579)
Start your day with complimentary breakfast at this Sikeston hotel. Enjoy free WiFi and parking while staying minutes from Central Park and the Sikeston Depot Museum. Cape Girardeau Municipal Airport is just a 29-minute drive away.

"Great place"
United States
Misty
The price is P3,496
P3,986 total
includes taxes & fees
Jan 6 - Jan 7
Super 8 by Wyndham Sikeston/Miner Area

Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very Good, (283)
Experience refreshing comfort at this Sikeston hotel with an indoor swimming pool and fitness center. Near Central Park and Sikeston Depot Museum, travelers appreciate the helpful staff, complimentary WiFi, and free parking for a convenient, stress-free stay.

"The hotel was very clean, beds were comfortable, and staff was friendly and helpful."
United States
aileen
The price is P5,203
P5,931 total
includes taxes & fees
Jan 11 - Jan 12
Comfort Inn & Suites Sikeston I-55

MainStay Suites Union City, TN

MainStay Suites Union City, TN
2.5 star property
Union City
8.6 out of 10, Excellent, (42)
Hiking trails surround this welcoming hotel with free breakfast and parking. The 24-hour fitness center and health club keep exercise routines on track, while in-room refrigerators and microwaves add convenience for extended stays.

"Very clean room, friendly staff! I would highly recommend this place! "
United States
Lydia
MainStay Suites Union City, TN

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (445)
Discover comfort at this Sikeston hotel with an indoor pool and fitness center. Enjoy complimentary breakfast, WiFi, and parking while exploring nearby Central Park and Sikeston Depot Museum. Guests consistently praise the helpful staff and immaculate rooms.

"Stay was excellent "
United States
Kourtney
The price is P5,474
P6,198 total
includes taxes & fees
Jan 11 - Jan 12
Holiday Inn Express & Suites Sikeston Southwest by IHG

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very Good, (727)
Enjoy tranquil accommodations at this welcoming Sikeston hotel where helpful staff receive consistent praise. Located near Central Park and Sikeston Depot Museum, guests appreciate the quiet atmosphere, clean rooms, and daily continental breakfast.

"Clean room and easy access to room"
United States
Anne
The price is P3,266
P3,723 total
includes taxes & fees
Jan 6 - Jan 7
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Reelfoot Lake Inn

Reelfoot Lake Inn
2.0 star property
Tiptonville
7.0 out of 10, Good, (464)
"I had a decent stay near Reelfoot Lake — definitely about a 2-star hotel. I appreciated that the room had tile floors instead of carpet, though they weren’t very clean or well-kept. The door barely locked, which was a bit concerning, and there were dogs barking throughout the night, making it hard to rest. That said, I was thankful to find a place at the last minute, and it served its purpose for a quick overnight stay."
United States
Allison
The price is P3,591
P4,120 total
includes taxes & fees
Jan 31 - Feb 1
Reelfoot Lake Inn

Hampton Inn Union City

Hampton Inn Union City
2.5 star property
Union City
9.6 out of 10, Exceptional, (167)
Located near County Market Place and Reelfoot Shopping Center, this welcoming hotel offers a free breakfast and convenient parking. Take a morning swim in the indoor pool after enjoying the complimentary meal. The helpful staff earns consistent praise from guests.

"Clean room, nice breakfast"
United States
STUART
The price is P6,999
P8,311 total
includes taxes & fees
Feb 1 - Feb 2
Hampton Inn Union City

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
2.5 star property
Sikeston
9.2 out of 10, Wonderful, (47)
This business-friendly hotel offers an indoor pool, restaurant, and complimentary breakfast. Located near Sikeston Depot Museum, guests enjoy free WiFi and parking while exploring local attractions.

"THE ROOM WAS SPOTLESS, CLEAN LOBBY, WARM AND LOT OF VARITY BREAKFAST, STAFF IS SO NICE."
United States
AHMAD
The price is P6,454
P7,308 total
includes taxes & fees
Jan 11 - Jan 12
Fairfield Inn & Suites by Marriott Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular East Prairie attractions

Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artifacts tell the story of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

Bridge over Mississippi River, New Orleans in background

Top East Prairie Hotel Reviews

More cheap stays in East Prairie

Find out more about East Prairie

Top reasons to visit East Prairie

  • Scenic Trails: East Prairie boasts beautiful trails ideal for hiking and skiing, perfect for outdoor enthusiasts.
  • Rich Cultural Experience: Explore local history museums and enjoy the area's cultural heritage amidst stunning landscapes.
  • Charming Neighbourhoods: The welcoming atmosphere of family-friendly neighbourhoods makes for a delightful exploration.
  • Proximity to Sikeston: Enjoy nearby shopping and excursions just a short drive away in Sikeston.
  • Diverse Accommodation: East Prairie offers a range of hotels to cater to all travellers' needs.

Find great hotels near East Prairie

Discover a variety of hotel accommodation options in East Prairie, Missouri, catering to diverse travellers' needs. Whether you seek pet-friendly lodgings, family-friendly environments, or facilities for business travel, East Prairie offers a selection of hotels and motels to suit your preferences. With numerous reviews available, finding the best hotel for your stay has never been easier. Enjoy a comfortable and memorable experience in this charming town.

  • Days Inn and Suites by Wyndham Sikeston: This hotel is designed for the modern traveller seeking a pet-friendly and business-focused experience. Located 17.7km from East Prairie, it offers a welcoming atmosphere for both leisure and work. Guests appreciate the convenience of on-site amenities that cater to their furry companions, including a flexible pet policy. The property ensures a comfortable stay with essential business facilities, making it an ideal choice for those balancing work and relaxation.
  • Pear Tree Inn Sikeston: Perfect for families and business travellers alike, Pear Tree Inn Sikeston combines comfort with practicality. Situated 17.7km from East Prairie, this hotel features amenities specifically catered for children, including free cribs, allowing families to travel with ease. Its pet-friendly policy adds to its appeal, ensuring that guests can bring their beloved pets along. The welcoming environment and attentive service make it a popular choice for those seeking a home-like atmosphere during their stay.
  • Drury Inn & Suites Sikeston, MO: As a 3-star establishment, Drury Inn & Suites Sikeston, MO offers a blend of comfort and inclusivity, welcoming LGBTQIA travellers with open arms. Just 17.7km away from East Prairie, this hotel stands out for its commitment to providing an exceptional experience for all guests. With its pet-friendly policy and business amenities, it caters to a diverse clientele. Guests often highlight the friendly atmosphere and quality service, ensuring a memorable retreat for both business and leisure visitors.

Where to stay near East Prairie

Discover the charm of East Prairie, Missouri, where outdoor enthusiasts and romantics alike can revel in picturesque scenery. Enjoy leisurely strolls in nearby parks or explore the welcoming atmosphere of family-friendly neighbourhoods. Just a short drive from downtown Sikeston, you'll find delightful shopping options and relaxing excursions that showcase the region's friendly spirit. Experience the perfect blend of adventure and tranquillity in this hidden gem of the Midwest.

  • Sikeston: Located 20.9km from East Prairie, Sikeston is a vibrant city offering a delightful mix of outdoor activities, family-friendly attractions, and romantic spots. With a steady influx of visitors, especially during the summer months, you can explore its charming recreational areas and shopping centres. Notable local landmarks include a picturesque lake and an event conference venue, making Sikeston an excellent base for both relaxation and adventure.
  • Anniston: Just 8.0km away from East Prairie, Anniston is a welcoming city perfect for families and outdoor enthusiasts. The visitor numbers remain relatively stable throughout the year, with a peak in the summer. Here, you can enjoy a variety of educational experiences and indulge in shopping at local centres and malls. Highlights include serene urban parks and a stadium, offering a lively atmosphere for both relaxation and entertainment.
  • Charleston: Situated 16.1km from East Prairie, Charleston is a city that captivates with its stunning scenery and adventurous spirit. The travel experience here is enhanced by its beautiful national state park and rich historical sites. Visitors flock to Charleston in spring and summer for its outdoor offerings and recreational facilities. The blend of adventure and exploration makes it a must-visit destination for those seeking both natural beauty and cultural experiences.

Things to do near East Prairie

East Prairie, Missouri, is an ideal destination for outdoor enthusiasts and those seeking a romantic getaway. Visitors can enjoy scenic trails and recreational areas, perfect for hiking and skiing. This charming locale offers a taste of prairie tourism, with major attractions that highlight its natural beauty and tranquil surroundings, making it a delightful spot for relaxation and exploration.

Shopping

The nearest shopping experience in East Prairie is at County Market Place, a vibrant shopping centre located 49.9km away. If you're up for a drive, you'll enjoy a mix of family-friendly stores and unique local businesses, perfect for finding gifts and souvenirs.

Recreation

Experience tranquillity at the East Prairie Wellness Centre, offering yoga classes and holistic therapies in a peaceful setting. For outdoor relaxation, visit the nearby Lake County Park, where you can enjoy walking trails, birdwatching, and picnicking amidst beautiful natural surroundings.

Adventure

The nearby Mississippi River offers thrilling opportunities for fishing, kayaking, and exploring its scenic shores. For a taste of local wildlife, visit the nearby wildlife refuges, where you can hike trails and enjoy birdwatching amidst stunning natural beauty.

Nightlife

Experience the charm of the Union City Masquerade Theatre, a delightful venue located 49.9km from East Prairie. Immerse yourself in an atmosphere rich with romance and culture, enjoying captivating performances that promise a memorable night out.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for East Prairie

For a budget-friendly visit to East Prairie, plan your trip between December and February when accommodation prices are lower, particularly on Sundays. Use Expedia's search tool to compare hotel rates and filter for eco-certified options. Consider booking a package that combines your hotel, flights, and activities for additional savings. Look for free local attractions, and utilise public transport to explore the area economically. By being strategic with your travel dates and using online resources, you can enjoy a memorable trip without overspending.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in East Prairie are December to February, where the prices are slightly lower. This is in comparison to April, June and August, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in East Prairie is Sunday. The most expensive day to stay in East Prairie is Saturday.
  • Find cheap hotels on Expedia: Expedia’s search tool enables you to specify your budget, desired location, and other preferences. You can arrange your search results to display prices from lowest to highest, making it easy to find the most affordable hotels first. Additionally, you have the option to refine your choices by hotel type; for instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly hotels that are available for booking.
  • Consider bundling your trip: You can save money by combining your East Prairie hotel reservation with your flights and activities through an Expedia package.

Find the best attractions in and around East Prairie

East Prairie, Missouri, is a charming destination perfect for outdoor enthusiasts and those seeking a romantic getaway. Visitors can explore a variety of attractions, including national and state parks, history museums, and event venues. The area offers a rich cultural experience amidst picturesque scenery, making it ideal for travellers interested in nature and history. Additionally, nearby attractions enhance the experience, providing ample opportunities for exploration and enjoyment.

  • Big Oak Tree State Park: Experience the grandeur of nature at Big Oak Tree State Park, known for its stunning scenery and adventure-filled outdoor activities. Wander through lush trails and witness some of the largest oak trees in the United States, creating a serene escape for nature enthusiasts.
  • City of Miner Convention Center: Located 17.7km from East Prairie, the City of Miner Convention Center is a hub for business events and conferences. Its modern facilities and professional atmosphere make it an ideal venue for networking and industry gatherings.
  • Central Park: Situated 20.9km away, Central Park offers a vibrant urban oasis perfect for family outings. Enjoy leisurely strolls, picnics, and recreational activities in a lively environment that captures the essence of city life.

Best time to go to East Prairie

The best time to visit East Prairie is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are moderately high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are moderately high and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January36.3°F (2.4°C)Light RainMostly SunnyModerately HighSlightly Low
February39.4°F (4.1°C)Light RainMostly SunnyAverageSlightly Low
March49.5°F (9.7°C)Light RainMostly SunnyAverageAverage
April58.5°F (14.7°C)Light RainMostly SunnyAverageSlightly High
May68.2°F (20.1°C)Light RainMostly SunnyAverageAverage
June77.0°F (25.0°C)Light RainMostly SunnyModerately HighSlightly High
July79.5°F (26.4°C)Light RainMostly SunnyModerately HighAverage
August77.5°F (25.3°C)Light RainMostly SunnyAverageSlightly High
September72.1°F (22.3°C)Light RainMostly SunnyAverageAverage
October60.8°F (16.0°C)Light RainMostly SunnyModerately LowAverage
November48.6°F (9.2°C)Light RainMostly SunnyModerately LowAverage
December41.2°F (5.1°C)Light RainMostly SunnyModerately LowSlightly Low

The nearest major airports for your trip to East Prairie

Accessing East Prairie, Missouri, is convenient via several nearby airports. Paducah, KY (PAH-Barkley Regional) is 62.8km away, with notable hotels such as The Respite Bed and Breakfast, Harrah's Metropolis Hotel & Casino, and Drury Inn Paducah, all within 14.5km of the airport. Cape Girardeau, MO (CGI-Cape Girardeau Municipal), located 51.5km away, offers options like Drury Plaza Hotel Cape Girardeau Conference Center and Pear Tree Inn, both within 9.7km. Cairo, IL (CIR-Cairo Regional) is the closest at 33.8km, with Quality Inn Cairo I-57 just 3.2km away, providing a comfortable stay for travellers.

Frequently asked questions

What's the best place for a stay in East Prairie?
Drury Inn & Suites Sikeston, MO, located 11.4 mi (18.4 km) from the heart of East Prairie, is a top choice for your stay based on our traveler data. Other good options for your visit to the area are Hampton Inn Sikeston and Best Western Plus Sikeston. See all available top hotels, or vacation rentals in East Prairie.
If I need to cancel my hotel reservation in East Prairie, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in East Prairie.
What's it like to stay in East Prairie?
Visitors are sure to enjoy all that East Prairie has to offer. There are 33 hotels and other accommodations in the surrounding area. Find out more about East Prairie.
What should I do while I'm visiting East Prairie?
The picturesque setting of Big Oak Tree State Park and Mississippi River exemplify the area's natural beauty. You'll also find Sikeston Depot Museum and New Madrid Historical Museum in the area. Check out what more to see and do in Expedia's East Prairie guide.
What's the weather like in East Prairie?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for East Prairie is 60 inches.

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