A bridge over a muddy river with green trees and hills in the background.

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Top Cities in Mississippi County

A sunset over a calm lake with tall trees reflected in the water.
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Charleston

Charleston
A tree-lined landscape with a river and fields.
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East Prairie

East Prairie

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Sep 18 - Sep 20
In two weeks
Sep 25 - Sep 27

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Our top choices for Mississippi County hotels

A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.

1. Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (666 reviews)
"Canceled"
United States
Crystal
The price is P3,722
P4,130 total
includes taxes & fees
Sep 14 - Sep 15
Super 8 by Wyndham Charleston/Sikeston East MO
A building with a fountain and flower beds in front.

2. The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (432 reviews)
"Everything was fine for a one night stay."
United States
Jay
The price is P4,159
P4,615 total
includes taxes & fees
Sep 14 - Sep 15
The Riverstone Hotel Charleston-Sikeston
A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.

3. Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (107 reviews)
"Great"
United States
Jackson
The price is P4,815
P5,344 total
includes taxes & fees
Sep 14 - Sep 15
Eagle Inn Charleston
A hotel lobby with a reception desk, seating area, and a large window.

4. Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.4 out of 10, (295 reviews)
"Good service,nice stuff and no complaints"
United States
Santiago
The price is P4,383
P4,864 total
includes taxes & fees
Oct 2 - Oct 3
Quality Inn Cairo I-57
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mississippi County Hotel Reviews

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

10/10 Excellent
"Canceled"
Crystal 4-night trip
Posted 1 day ago
Super 8 by Wyndham Charleston/Sikeston East MO