A red train on tracks, palm trees, and modern buildings.

Business Hotels in Central San Diego, San Diego

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Check availability on Central San Diego Business Hotels

Tonight
Sep 24 - Sep 25
Tomorrow
Sep 25 - Sep 26
This weekend
Sep 25 - Sep 27
Next weekend
Oct 2 - Oct 4

Our top choices for Central San Diego business-friendly hotels

A breakfast buffet area with a stone wall, a coffee station, and a fruit display.
A hotel lobby with leather armchairs, a sofa, and a reception desk.
A table with two gold-framed lamps and a vase of white flowers.
A modern hotel lobby with a fireplace, comfortable seating, and a large painting of a sunset.

1. Hampton Inn San Diego-Kearny Mesa

Hampton Inn San Diego-Kearny Mesa
Kearny Mesa
United States
Paola
P7,453
P8,552 total
includes taxes & fees
Oct 25 - Oct 26
Hampton Inn San Diego-Kearny Mesa
A modern bar area with wooden ceiling beams, bar stools, and a long counter.
A hotel with a swimming pool, outdoor seating, and a courtyard.
A hotel room with two beds, a desk, a chair, a TV, and a balcony with a view.
A multi-story hotel with a curved facade, balconies, and a central entrance with a glass door.

2. Courtyard by Marriott San Diego Central

Courtyard by Marriott San Diego Central
Kearny Mesa
United States
Johanna
P9,244
P10,626 total
includes taxes & fees
Oct 4 - Oct 5
Courtyard by Marriott San Diego Central
A modern lobby with a stone wall, blue sofas, a reception desk, and a staircase.
A restaurant with booths and tables, a counter, and a mural on the wall.
A lobby with a stone wall, blue sofa, purple chairs, and a patterned rug.
A hotel pool area with a circular pool, lounge chairs, umbrellas, and palm trees.

3. Kings Inn San Diego

Kings Inn San Diego
Mission Valley
United States
Armando
P4,322
P4,959 total
includes taxes & fees
Oct 25 - Oct 26
Kings Inn San Diego
A modern hotel with a glass entrance, outdoor seating, and palm trees.
A modern hotel lobby with a sofa, chairs, a coffee table, and a TV.
A modern living room with a fireplace, grey sofas, and a bookshelf.
A hotel room with two beds, a sofa, a desk, and a lamp.

4. Hilton Garden Inn San Diego Mission Valley Stadium

Hilton Garden Inn San Diego Mission Valley Stadium
Kearny Mesa
United States
KELLEY
P8,009
P9,206 total
includes taxes & fees
Sep 27 - Sep 28
Hilton Garden Inn San Diego Mission Valley Stadium
A hotel lobby with a 'Lobby' sign, palm trees, and a sunset sky.
A restaurant with a bar area, booths, and a view of the sunset through large windows.
A gym with treadmills, elliptical machines, and a stationary bike.
An outdoor patio area with tables and chairs, red umbrellas, and a view of palm trees and a building with a 'BLW' sign.

5. Best Western Seven Seas

Best Western Seven Seas
Mission Valley
United States
Benjamin
P5,299
P6,090 total
includes taxes & fees
Sep 27 - Sep 28
Best Western Seven Seas
An outdoor patio with wicker furniture, a stone fire pit, and blue umbrellas.
A spacious living area with a large sofa, a coffee table, and a staircase leading to an upper level.
A Hyatt House hotel entrance with a covered walkway, palm trees, and well-lit signage.
A bar area with wooden chairs and tables, a TV screen, and a variety of bottles and glasses on the shelves.

6. HYATT house San Diego/Sorrento Mesa

HYATT house San Diego/Sorrento Mesa
Sorrento Valley
United States
Balwinder
P10,585
P12,167 total
includes taxes & fees
Oct 1 - Oct 2
HYATT house San Diego/Sorrento Mesa
A modern kitchen with a central island, wooden chairs, and a flat-screen TV mounted on the wall.
A modern kitchen with wooden cabinets, stainless steel appliances, a white countertop, and a built-in bench with white cushions.
A laundry facility with multiple washing machines, a clock, and a wooden bench.
A hotel room with a bed, a sofa, a desk, and a view of the city.

7. Element by Marriott San Diego Mission Valley

Element by Marriott San Diego Mission Valley
Mission Valley
United States
Famil
P10,084
P11,591 total
includes taxes & fees
Oct 25 - Oct 26
Element by Marriott San Diego Mission Valley
A multi-story hotel with a central entrance, palm trees, and a clear blue sky.
A swimming pool with lounge chairs and umbrellas, surrounded by trees and a building.
A restaurant with a bar area, multiple seating options including round tables and booths, and a visible menu board.
A hotel lobby with a stone wall, a fireplace, a sectional sofa, a coffee table, and a reception desk.

8. Country Inn & Suites by Radisson, San Diego North, CA

Country Inn & Suites by Radisson, San Diego North, CA
Sorrento Valley
United States
Peter
P9,529
P10,953 total
includes taxes & fees
Oct 18 - Oct 19
Country Inn & Suites by Radisson, San Diego North, CA
A spacious living area with a fireplace, seating, and a large red accent wall.
A hotel room with a large bed, a TV on a wooden cabinet, a desk with a chair, and a window with curtains.
A spacious lobby with a reception desk, seating area, and vending machines.
A hotel entrance with a covered walkway, palm trees, and a parking lot.

9. Ramada Suites by Wyndham San Diego/Hotel Circle Area

Ramada Suites by Wyndham San Diego/Hotel Circle Area
Mission Valley
United States
William
P4,525
P5,201 total
includes taxes & fees
Sep 29 - Sep 30
Ramada Suites by Wyndham San Diego/Hotel Circle Area
A pathway flanked by neatly trimmed hedges and a building with a balcony.
A courtyard with a small pond, palm trees, and a building with balconies.
A lobby with a mosaic fountain, seating area, and a book display.
A courtyard with a small water feature surrounded by rocks and greenery.

10. California Suites Hotel

California Suites Hotel
Clairemont
United States
Mathew
P5,580
P6,404 total
includes taxes & fees
Sep 27 - Sep 28
California Suites Hotel
View all properties

Top Central San Diego Hotel Reviews

Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG

10/10 Excellent
"I recommend everyone to stay here , absolutely friendly, clean , professional, friendly."
Rosalinda 1-night trip
Posted less than an hour ago
Crowne Plaza San Diego - Mission Valley by IHG
The Alcala Hotel Mission Valley/Seaworld

The Alcala Hotel Mission Valley/Seaworld

10/10 Excellent
"I stayed here years ago, and the property has definitely been upgraded. The staff is great too! Raul and Fermin, thanks for all of the help. The continental breakfast is a nice touch too."
Andrew 1-night trip
Posted 1 hour ago
The Alcala Hotel Mission Valley/Seaworld
Best Western Seven Seas

Best Western Seven Seas

10/10 Excellent
"m"
Ailyn 1-night trip
Posted 1 hour ago
Best Western Seven Seas
Kings Inn San Diego

Kings Inn San Diego

10/10 Excellent
"This place is just amazing. The rooms are near perfect."
Ernesto 1-night trip
Posted 1 hour ago
Kings Inn San Diego
Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

10/10 Excellent
"We came out for a quick weekend trip from Vegas . Weather was amazing ! Hotel was very clean , comfy beds , nice staff. Breakfast is the only thing o was disappointed in . The only good thing was the waffles , toast , and bagels . That’s carbs carbs on top of carbs. Eggs tastes like they came out of a box and the meat , smelled like dog food w a blend taste yuck . Potatoes were cold and tasted old , again maybe boxed . Definitely did not enjoy the “free breakfast “ so we made sure to go out to breakfast the next morning. We went found to pacific beach and ate at a burrito spot called Early Bird very highly recommended. Other than that . Yes I would stay here again ."
Carolina 2-night trip
Posted 3 hours ago
Hampton Inn San Diego/Mission Valley
The Atwood Hotel San Diego - SeaWorld/Zoo

The Atwood Hotel San Diego - SeaWorld/Zoo

8/10 Good
"The lobby was clean and the staff was nice. My unit was upstairs and it was clean and smelled really good too the only thing was the bathroom doesn’t have a working fan so I showered with the window open….you’re welcome."
Robert 1-night trip
Posted 2 days ago
The Atwood Hotel San Diego - SeaWorld/Zoo
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

10/10 Excellent
"Affordability and location can’t be beat. Staff is extremely helpful and attentive, and the amenities are great."
Karla 1-night trip
Posted 2 days ago
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

Frequently asked questions

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